Formation of α-hydroxy-β-diketones through hydroxylation of isoxazolium salts: Stereoselective approach to angular cis-diols in polycyclic systems

Angewandte Chemie - International Edition

Volumn 47, Issue 39, 2008, Pages 7446-7449

  Takikawa, Hiroshi ^a   Takada, Akiomi ^a   Hikita, Katsuyoshi ^a   Suzuki, Keisuke ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Alkylation; Asymmetric synthesis; Hydroxylation; Isoxazoles; Polyketides

Indexed keywords

CHEMICAL REACTIONS; KETONES; RAW MATERIALS;

ALKYLATION; ASYMMETRIC SYNTHESIS; HYDROXYLATION; ISOXAZOLES; POLYKETIDES;

POLYMERS;

INORGANIC SALT; ISOXAZOLE DERIVATIVE; KETONE;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; HYDROXYLATION; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HYDROXYLATION; ISOXAZOLES; KETONES; MODELS, MOLECULAR; MOLECULAR STRUCTURE; SALTS; STEREOISOMERISM;

EID: 54749116930     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200801586     Document Type: Article

References (52)

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49. 2O.
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51. The position of chlorination was confirmed by X-ray analysis of the chlorinated product. See the Supporting Information.
52. Other solvents (THF, DMF, acetone)for the hydrolysis gave mixtures of 8e and unidentified byproducts.