Structural analysis of the contacts anchoring moenomycin to peptidoglycan glycosyltransferases and implications for antibiotic design

ACS Chemical Biology

Volumn 3, Issue 7, 2008, Pages 429-436

  Yuan, Yanqiu ^a   Fuse, Shinichiro ^b   Ostash, Bohdan ^a,c   Sliz, Piotr ^a   Kahne, Daniel ^b   Walker, Suzanne ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b HARVARD UNIVERSITY   (United States)

^c IVAN FRANKO NATIONAL UNIVERSITY OF LVIV   (Ukraine)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; BAMBERMYCIN; MUTANT PROTEIN; PAROMOMYCIN; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; PROTEIN PBP1A; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; OLIGOSACCHARIDE;

ANTIMICROBIAL ACTIVITY; AQUIFEX AEOLICUS; ARTICLE; DRUG DESIGN; DRUG STRUCTURE; ENZYME ACTIVITY; INFORMATION PROCESSING; MUTATIONAL ANALYSIS; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN DOMAIN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; PROTEIN TERTIARY STRUCTURE; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

AQUIFEX AEOLICUS; BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS;

ANTI-BACTERIAL AGENTS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; OLIGOSACCHARIDES; PEPTIDOGLYCAN GLYCOSYLTRANSFERASE; PROTEIN STRUCTURE, TERTIARY; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 54749100874     PISSN: 15548929     EISSN: None     Source Type: Journal    
DOI: 10.1021/cb800078a     Document Type: Article

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