A detailed methodology of partial hepatectomy in the mouse

Lab Animal

Volumn 37, Issue 11, 2008, Pages 529-532

  Boyce, Stephen ^a   Harrison, David ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; ANIMAL DISEASE; ARTICLE; DISEASE MODEL; EXPERIMENTAL ANIMAL; LIVER; LIVER RESECTION; METHODOLOGY; MOUSE;

ANIMALS; ANIMALS, LABORATORY; DISEASE MODELS, ANIMAL; HEPATECTOMY; LIVER; MICE;

MURINAE; MUS;

EID: 54549118155     PISSN: 00937355     EISSN: 15484475     Source Type: Journal    
DOI: 10.1038/laban1108-529     Document Type: Article

References (11)

1. Higgins, G. & Anderson, R.M. Experimental pathology of the liver. I. Restoration of the liver of the white rat following surgical removal. Arch. Pathol. 12, 186-206 (1931).
2. Greene, A.K. & Puder, M. Partial hepatectomy in the mouse: technique and perioperative management. J. Invest. Surg. 16, 99-102 (2003).
3. Martins, P.N., Theruvath, T.P. & Neuhaus, P. Rodent models of partial hepatectomies. Liver Int. 28, 3-11 (2008).
4. Martins, P.N. & Neuhaus, P. Hepatic lobectomy and segmentectomy models using microsurgical techniques. Microsurgery 28, 187-191 (2008).
5. Koniaris, L.G., McKillop, I.H., Schwartz, S.I. & Zimmers, T.A. Liver regeneration. J. Am. Coll. Surg. 197, 634-659 (2003).
6. Martins, P.N. & Neuhaus, P. Surgical anatomy of the liver, hepatic vasculature and bile ducts in the rat. Liver Int. 27, 384-392 (2007).
7. Bucher, N.L. & Swaffield, M.N. The rate of incorporation of labeled thymidine into the deoxyribonucleic acid of regenerating rat liver in relation to the amount of liver excised. Cancer Res. 24, 1611-1625 (1964).
8. Desbarats, J. & Newell, M.K. Fas engagement accelerates liver regeneration after partial hepatectomy. Nat. Med. 6, 920-923 (2000).
9. Albrecht, J.H., Meyer, A.H. & Hu, M.Y. Regulation of cyclin-dependent kinase inhibitor p21(WAF1/Cip1/Sdi1) gene expression in hepatic regeneration. Hepatology 25, 557-563 (1997).
10. Jaime, M. et al. The p21(Cip1) protein, a cyclin inhibitor, regulates the levels and the intracellular localization of CDC25A in mice regenerating livers. Hepatology 35, 1063-1071 (2002).
11. Waynforth, H.B. & Flecknell, P.A. Experimental and Surgical Technique in the Rat 241 (Academic, San Diego, 1992).