Does Preoperative Statin Therapy Improve Outcomes in Patients Undergoing Isolated Cardiac Valve Surgery?

American Journal of Cardiology

Volumn 102, Issue 9, 2008, Pages 1235-1239

  Virani, Salim S ^a,b   Nambi, Vijay ^a,c   Lee, Vei Vei ^b   Elayda, MacArthur ^a,b   Reul, Ross M ^b   Wilson, James M ^a,b   Ballantyne, Christie M ^a,c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b ST LUKE S EPISCOPAL HOSPITAL   (United States)

^c HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ATORVASTATIN; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CERIVASTATIN; FLUINDOSTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; MEVINOLIN; PRAVASTATIN; ROSUVASTATIN; SIMVASTATIN;

AGED; AGING; ARTICLE; CARDIOPULMONARY BYPASS; COHORT ANALYSIS; COMORBIDITY; CONGESTIVE HEART FAILURE; FEMALE; HEART INFARCTION; HEART VALVE REPLACEMENT; HEART VALVE SURGERY; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; OPERATION DURATION; OUTCOME ASSESSMENT; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; STROKE; SURGICAL MORTALITY; TREATMENT OUTCOME;

CARDIAC SURGICAL PROCEDURES; FEMALE; HEART VALVES; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; MALE; MIDDLE AGED; PREOPERATIVE CARE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 54549116125     PISSN: 00029149     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjcard.2008.06.055     Document Type: Article

References (21)

1. Hoda M.R., El-Achkar H., Schmitz E., Scheffold T., Vetter H.O., and De Simone R. Systemic stress hormone response in patients undergoing open heart surgery with or without cardiopulmonary bypass. Ann Thorac Surg 82 (2006) 2179-2186
2. Elahi M.M., Khan J.S., and Matata B.M. Deleterious effects of cardiopulmonary bypass in coronary artery surgery and scientific interpretation of off-pump's logic. Acute Card Care 8 (2006) 196-209
3. Gravlee G.P. Update on cardiopulmonary bypass. Curr Opin Anaesthesiol 14 (2001) 11-16
4. de Mendonca-Filho H.T., Pereira K.C., Fontes M., Vieira D.A., de Mendonca M.L., Campos L.A., and Castro-Faria-Neto H.C. Circulating inflammatory mediators and organ dysfunction after cardiovascular surgery with cardiopulmonary bypass: a prospective observational study. Crit Care 10 (2006) R46
5. Ramlawi B., Rudolph J.L., Mieno S., Feng J., Boodhwani M., Khabbaz K., Levkoff S.E., Marcantonio E.R., Bianchi C., and Sellke F.W. C-reactive protein and inflammatory response associated to neurocognitive decline following cardiac surgery. Surgery 140 (2006) 221-226
6. Liakopoulos O.J., Dorge H., Schmitto J.D., Nagorsnik U., Grabedunkel J., and Schoendube F.A. Effects of preoperative statin therapy on cytokines after cardiac surgery. Thorac Cardiovasc Surg 54 (2006) 250-254
7. Chello M., Patti G., Candura D., Mastrobuoni S., Di Sciascio G., Agro F., Carassiti M., and Covino E. Effects of atorvastatin on systemic inflammatory response after coronary bypass surgery. Crit Care Med 34 (2006) 660-667
8. Lefer A.M., Campbell B., Shin Y.K., Scalia R., Hayward R., and Lefer D.J. Simvastatin preserves the ischemic-reperfused myocardium in normocholesterolemic rat hearts. Circulation 100 (1999) 178-184
9. Chen J., Nagasawa Y., Zhu B.M., Ohmori M., Harada K., Fujimura A., and Hashimoto K. Pravastatin prevents arrhythmias induced by coronary artery ischemia/reperfusion in anesthetized normocholesterolemic rats. J Pharmacol Sci 93 (2003) 87-94
10. Naidu B.V., Woolley S.M., Farivar A.S., Thomas R., Fraga C., and Mulligan M.S. Simvastatin ameliorates injury in an experimental model of lung ischemia-reperfusion. J Thorac Cardiovasc Surg 126 (2003) 482-489
11. Wan M.X., Schramm R., Klintman D., Welzenbach K., Weitz-Schmidt G., and Thorlacius H. A statin-based inhibitor of lymphocyte function antigen-1 protects against ischemia/reperfusion-induced leukocyte adhesion in the colon. Br J Pharmacol 140 (2003) 395-401
12. Lazar H.L., Bao Y., Zhang Y., and Bernard S.A. Pretreatment with statins enhances myocardial protection during coronary revascularization. J Thorac Cardiovasc Surg 125 (2003) 1037-1042
13. Pan W., Pintar T., Anton J., Lee V.V., Vaughn W.K., and Collard C.D. Statins are associated with a reduced incidence of perioperative mortality after coronary artery bypass graft surgery. Circulation 110 suppl (2004) II45-II49
14. Dotani M.I., Elnicki D.M., Jain A.C., and Gibson C.M. Effect of preoperative statin therapy and cardiac outcomes after coronary artery bypass grafting. Am J Cardiol 86 (2000) 1128-1130
15. Bell R.M., and Yellon D.M. Atorvastatin, administered at the onset of reperfusion, and independent of lipid lowering, protects the myocardium by up-regulating a pro-survival pathway. J Am Coll Cardiol 41 (2003) 508-515
16. Chello M., Goffredo C., Patti G., Candura D., Melfi R., Mastrobuoni S., Di Sciascio G., and Covino E. Effects of atorvastatin on arterial endothelial function in coronary bypass surgery. Eur J Cardiothorac Surg 28 (2005) 805-810
17. Patti G., Chello M., Candura D., Pasceri V., D'Ambrosio A., Covino E., and Di Sciascio G. Randomized trial of atorvastatin for reduction of postoperative atrial fibrillation in patients undergoing cardiac surgery: results of the ARMYDA-3 (Atorvastatin for Reduction of MYocardial Dysrhythmia After cardiac surgery) study. Circulation 114 (2006) 1455-1461
18. Virani S.S., Nambi V., Razavi M., Lee V.-V., Elayda M., Wilson J.M., and Ballantyne C.M. Preoperative statin therapy is not associated with a decrease in the incidence of postoperative atrial fibrillation in patients undergoing cardiac surgery. Am Heart J 155 (2008) 541-546
19. Clark L.L., Ikonomidis J.S., Crawford Jr. F.A., Crumbley III A., Kratz J.M., Stroud M.R., Woolson R.F., Bruce J.J., Nicholas J.S., Lackland D.T., Zile M.R., and Spinale F.G. Preoperative statin treatment is associated with reduced postoperative mortality and morbidity in patients undergoing cardiac surgery: an 8-year retrospective cohort study. J Thorac Cardiovasc Surg 131 (2006) 679-685
20. Ali I.S., and Buth K.J. Preoperative statin use and in-hospital outcomes following heart surgery in patients with unstable angina. Eur J Cardiothorac Surg 27 (2005) 1051-1056
21. Kjekshus J., Apetrei E., Barrios V., Bohm M., Cleland J.G., Cornel J.H., Dunselman P., Fonseca C., Goudev A., Grande P., et al., CORONA Group. Rosuvastatin in older patients with systolic heart failure. N Engl J Med 357 (2007) 2248-2261