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Volumn 144, Issue 5, 2008, Pages 721-724

The phosphatidylinositol 3-kinase/akt signaling pathway in medullary thyroid cancer

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CHROMOGRANIN A; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN RET;

EID: 54549114194     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.surg.2008.06.028     Document Type: Review
Times cited : (27)

References (10)
  • 1
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    • Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid cancer
    • Drosten M., Hilken G., Böckmann M., Rödicker F., Mise N., Cranston A.N., et al. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid cancer. J NCI 96 (2004) 1231-1239
    • (2004) J NCI , vol.96 , pp. 1231-1239
    • Drosten, M.1    Hilken, G.2    Böckmann, M.3    Rödicker, F.4    Mise, N.5    Cranston, A.N.6
  • 2
    • 3242687685 scopus 로고    scopus 로고
    • Antiproliferative effects of Src inhibition on medullary thyroid cancer
    • Liu Z., Falola J., Zhu X., Gu Y., Kim L.T., Sarosi G.A., et al. Antiproliferative effects of Src inhibition on medullary thyroid cancer. J Clin Endocrinology 89 (2004) 3503-3509
    • (2004) J Clin Endocrinology , vol.89 , pp. 3503-3509
    • Liu, Z.1    Falola, J.2    Zhu, X.3    Gu, Y.4    Kim, L.T.5    Sarosi, G.A.6
  • 3
    • 33845626635 scopus 로고    scopus 로고
    • Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002
    • Kunnimalaiyaan M., Ndiaye M., and Chen H. Apoptosis-mediated medullary thyroid cancer growth suppression by the PI3K inhibitor LY294002. Surgery 140 (2006) 1009-1015
    • (2006) Surgery , vol.140 , pp. 1009-1015
    • Kunnimalaiyaan, M.1    Ndiaye, M.2    Chen, H.3
  • 4
    • 0346887056 scopus 로고    scopus 로고
    • The role of human achaete-scute homolog-1 in medullary thyroid cancer cells
    • Sippel R.S., Carpenter J.E., Kunnimalaiyaan M., and Chen H. The role of human achaete-scute homolog-1 in medullary thyroid cancer cells. Surgery 134 (2003) 866-871
    • (2003) Surgery , vol.134 , pp. 866-871
    • Sippel, R.S.1    Carpenter, J.E.2    Kunnimalaiyaan, M.3    Chen, H.4
  • 5
    • 33748132208 scopus 로고    scopus 로고
    • In-vivo activation of Raf-1 inhibits tumor growth and development in a xenograft model of human medullary thyroid cancer
    • Vaccaro A., Chen H., and Kunimalaiyaan M. In-vivo activation of Raf-1 inhibits tumor growth and development in a xenograft model of human medullary thyroid cancer. Anticancer Drugs 17 (2006) 849-853
    • (2006) Anticancer Drugs , vol.17 , pp. 849-853
    • Vaccaro, A.1    Chen, H.2    Kunimalaiyaan, M.3
  • 6
    • 33845987566 scopus 로고    scopus 로고
    • Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells
    • Kunnimalaiyaan M., Vaccaro A.M., Ndiaye M.A., and Chen H. Overexpression of the NOTCH1 intracellular domain inhibits cell proliferation and alters the neuroendocrine phenotype of medullary thyroid cancer cells. J Biol Chem 281 (2006) 39819-39830
    • (2006) J Biol Chem , vol.281 , pp. 39819-39830
    • Kunnimalaiyaan, M.1    Vaccaro, A.M.2    Ndiaye, M.A.3    Chen, H.4
  • 7
    • 34147168760 scopus 로고    scopus 로고
    • Inactivation of glycogen synthase-3β, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells
    • Kunnimalaiyaan M., Vaccaro A.M., Ndiaye M.A., and Chen H. Inactivation of glycogen synthase-3β, a downstream target of the raf-1 pathway, is associated with growth suppression in medullary thyroid cancer cells. Mol Cancer Ther 6 (2007) 1151-1158
    • (2007) Mol Cancer Ther , vol.6 , pp. 1151-1158
    • Kunnimalaiyaan, M.1    Vaccaro, A.M.2    Ndiaye, M.A.3    Chen, H.4
  • 8
    • 0142227019 scopus 로고    scopus 로고
    • Targeting the PI3K-Akt pathway in human cancer: rationale and promise
    • Luo J., Manning B.D., and Cantley L.C. Targeting the PI3K-Akt pathway in human cancer: rationale and promise. Cancer Cell 4 (2003) 257-262
    • (2003) Cancer Cell , vol.4 , pp. 257-262
    • Luo, J.1    Manning, B.D.2    Cantley, L.C.3
  • 9
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    • Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/Akt signaling pathway
    • Segouffin-Cariou C., and Billaud M. Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/Akt signaling pathway. J Biol Chem 275 (2000) 3568-3576
    • (2000) J Biol Chem , vol.275 , pp. 3568-3576
    • Segouffin-Cariou, C.1    Billaud, M.2
  • 10
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    • Increased in vivo phosphorylation of Ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B
    • Salvatore D., Melillo R.M., Monaco C., Visconti R., Gianfranco F., Vecchio G., et al. Increased in vivo phosphorylation of Ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B. Cancer Res 16 (2001) 1426-1431
    • (2001) Cancer Res , vol.16 , pp. 1426-1431
    • Salvatore, D.1    Melillo, R.M.2    Monaco, C.3    Visconti, R.4    Gianfranco, F.5    Vecchio, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.