The role of human achaete-scute homolog-1 in medullary thyroid cancer cells

Surgery

Volumn 134, Issue 6, 2003, Pages 866-871

  Sippel, Rebecca S ^a   Carpenter, Jennifer E ^a   Kunnimalaiyaan, Muthusamy ^a   Chen, Herbert ^a,b   Nwariaku, Fiemu ^c   Carling, Tobias ^c   Olson, John E ^c   Zeiger, Martha A ^c  

^a UNIVERSITY OF WISCONSIN   (United States)

^b UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CALCITONIN; CHROMOGRANIN A; ESTRADIOL; MITOGEN ACTIVATED PROTEIN KINASE 1; RAF PROTEIN; RAF1 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR MASH1; UNCLASSIFIED DRUG;

CONFERENCE PAPER; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; HORMONAL REGULATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; THYROID MEDULLARY CARCINOMA; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

EID: 0346887056     PISSN: 00396060     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6060(03)00418-5     Document Type: Conference Paper

References (16)

1. Chen H, Roberts JR, Ball DW, Eisele DW, Baylin SB, Udelsman R, et al. Effective long-term palliation of symptomatic, incurable metastatic medullary thyroid cancer by operative resection. Ann Surg 1998;227:887-95.
2. Udelsman R, Chen H. The current management of thyroid cancer. Adv Surg 1999;33:1-27.
3. Moley JF, Lairmore TC, Phay JE. Hereditary endocrinopathies. Curr Probl Surg 1999;36:653-762.
4. Guillemot F, Joyner AL. Dynamic expression of the murine achaete-scute homologue mash-1 in the developing nervous system. Mech Dev 1993;42:171-85.
5. Ball DW, Azzoli CG, Baylin SB, Chi D, Dou S, Donis-Keller H, et al. Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors. Proc Natl Acad Sci USA 1993;90:5648-52.
6. Chen H, Udelsman R, Zeiger MA, Ball DW. Human achaete-scute homolog-1 is highly expressed in a subset of neuroendocrine tumors. Oncol Rep 1997;4:775-8.
7. Borges M, Linnoila RI, van de Velde HJ, Chen H, Nelkin BD, Mabry M, et al. An achaete-scute homologue essential for neuroendocrine differentiation in the lung. Nature 1997;386:852-5.
8. Lanigan TM, DeRaad SK, Russo AF. Requirement of the MASH-1 transcription factor for neuroendocrine differentiation of thyroid C cells. J Neurobiol 1998;34:126-34.
9. Chen H, Carson-Walter EB, Baylin SB, Nelkin BD, Ball DW. Differentiation of medullary thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1. Surgery 1996;120:168-72.
10. Carson-Walter EB, Smith DP, Ponder BA, Baylin SB, Nelkin BD. Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells. Oncogene 1998;17:367-76.
11. Sippel RS, Chen H. Activation of the ras/raf-1 signal transduction pathway in carcinoid tumor cells results in morphologic transdifferentiation. Surgery 2002;132:1035-9.
12. Sippel RS, Carpenter JE, Kunnimalaiyaan M, Lagerholm S, Chen H. Raf-1 activation suppresses neuroendocrine marker and hormone levels in human gastrointestinal carcinoid cells. Am J Physiol Gastrointest Liver Physiol 2003;285: G245-54.
13. Sippel RS, Chen H. Update on carcinoid tumors. Probl Gen Surg [In press].
14. Chen H, Thiagalingam A, Chopra H, Borges MW, Feder JN, Nelkin BD, et al. Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression. Proc Natl Acad Sci U S A 1997;94:5355-60.
15. Chen H, Biel MA, Borges MW, Thiagalingam A, Nelkin BD, Baylin SB, et al. Tissue-specific expression of human achaete-scute homologue-1 in neuroendocrine tumors: transcriptional regulation by dual inhibitory regions. Cell Growth Differ 1997;8:677-86.
16. Park JI, Strock CJ, Ball DW, Nelkin BD. The Ras/Raf/MEK/ extracellular signal-regulated kinase pathway induces autocrine-paracrine growth inhibition via the leukemia inhibitory factor/JAK/STAT pathway. Mol Cell Biol 2003;23:543-54.