Role of the lateral hypothalamus in modulating responses of parabrachial gustatory neurons in the rat

Brain Research Bulletin

Volumn 77, Issue 4, 2008, Pages 165-171

  Lei, Qi ^a,b   Yan, Jianqun ^a   Huang, Tao ^a   Shi, Jinghong ^a   Yang, Xuejuan ^a   Lv, Bo ^a   Li, Qiang ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b SHAANXI PROVINCIAL PEOPLE S HOSPITAL   (China)

Author keywords

Electrical stimulation; Electrolytic lesion; Lateral hypothalamus; Parabrachial nucleus; Taste

Indexed keywords

HYDROCHLORIC ACID; QUININE; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROLYSIS; ELECTROSTIMULATION; GUSTATORY NERVOUS SYSTEM; LATERAL HYPOTHALAMUS; MICROPHOTOGRAPHY; NERVE STIMULATION; NERVOUS SYSTEM FUNCTION; NEUROMODULATION; NONHUMAN; PARABRACHIAL NUCLEUS; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; TASTE;

ACTION POTENTIALS; ANIMALS; DIETARY SUCROSE; ELECTRIC STIMULATION; EVOKED POTENTIALS, SOMATOSENSORY; HYDROCHLORIC ACID; HYPOTHALAMUS; MALE; MICROELECTRODES; NEURAL INHIBITION; NEURONS; PHYSICAL STIMULATION; PONS; QUININE; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHLORIDE; TASTE PERCEPTION;

EID: 54549113378     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2008.05.006     Document Type: Article

References (32)

1. Bäckberg M., Ultenius C., Fritschy J.M., and Meister B. Cellular localization of GABA receptor alpha subunit immunoreactivity in the rat hypothalamus: relationship with neurones containing orexigenic or anorexigenic peptides. J. Neuroendocrinol. 16 (2004) 589-604
2. Cho Y.K., Li C.S., and Smith D.V. Taste responses of neurons of the hamster solitary nucleus are enhanced by lateral hypothalamic stimulation. J. Neurophysiol. 87 (2002) 1981-1992
3. Cho Y.K., Li C.S., and Smith D.V. Descending influences from the lateral hypothalamus and amygdala converge onto medullary taste neurons. Chem. Senses 28 (2003) 155-171
4. Di Lorenzo P.M., and Monroe S. Taste responses in the parabrachial pons of male, female and pregnant rats. Brain Res. Bull. 23 (1989) 219-227
5. Di Lorenzo P.M., and Monroe S. Corticofugal input to taste-responsive units in the parabrachial pons. Brain Res. Bull. 29 (1992) 925-930
6. Halsell C.B., and Frank M.E. Organization of parabrachial nucleus efferents to the thalamus and amygdala in the golden hamster. J. Comp. Neurol. 317 (1992) 57-78
7. Hosoya Y., and Matsushita M. Brainstem projections from the lateral hypothalamic area in the rat, as studied with autoradiography. Neurosci. Lett. 24 (1981) 111-116
8. Huang T., Yan J.Q., and Kang Y. Role of the central amygdaloid nucleus in shaping the discharge of gustatory neurons in the rat parabrachial nucleus. Brain Res. Bull. 61 (2003) 443-452
9. Kang Y., Yan J.Q., and Huang T. Microinjection of bicuculline into the central nucleus of the amygdala alters gustatory responses of the rat parabrachial nucleus. Brain Res. 1028 (2004) 39-47
10. Kang Y., Yan J.Q., and Huang T. Involvement of AMPA receptors in mediation of the central amygdaloid nucleus modulating the parabrachial nucleus taste response in rats. Acta Physiol. Sin. 56 (2004) 671-677
11. Kathryn G.C., Lee-Ming K., Teresa A.M., and Donald W.P. In the ventromedial nucleus of the rat hypothalamus, GABA-immunolabeled neurons are abundant and are innervated by both enkephalin- and GABA-immunolabeled axon terminals. Brain Res. 816 (1999) 58-67
12. Li C.S., and Smith D.V. Glutamate receptor antagonists block gustatory afferent input to the nucleus of the solitary tract. J. Neurophysiol. 77 (1997) 1514-1525
13. Li C.S., Cho Y.K., and Smith D.V. Taste responses of neurons in the hamster solitary nucleus are modulated by the central nucleus of the amygdala. J. Neurophysiol. 88 (2002) 2979-2992
14. Li C.S., Cho Y.K., and Smith D.V. Modulation of parabrachial taste neurons by electrical and chemical stimulation of the lateral hypothalamus and amygdala. J. Neurophysiol. 93 (2005) 1183-1196
15. Lundy R.F., and Norgren R. Activity in the hypothalamus, amygdala, and cortex generates bilateral and convergent modulation of pontine gustatory neurons. J. Neurophysiol. 91 (2004) 1143-1157
16. Meister B. Neurotransmitters in key neurons of the hypothalamus that regulate feeding behavior and body weight. Physiol. Behav. 92 (2007) 263-271
17. Moga M.M., Herbert H., Hurley K.M., Yasui Y., Gray T.S., and Saper C.B. Organization of cortical, basal forebrain, and hypothalamic afferents to the parabrachial nucleus in the rat. J. Comp. Neurol. 295 (1990) 624-661
18. Norgren R., and Pfaffmann C. The pontine taste area in the rat. Brain Res. 91 (1975) 99-117
19. Norgren R. Taste pathways to hypothalamus and amygdala. J. Comp. Neurol. 166 (1976) 17-30
20. Otawa S., Takagi K., and Ogawa H. NMDA and non-NMDA receptors mediate taste afferent inputs to cortical taste neurons in rats. Exp. Brain Res. 106 (1995) 391-402
21. Paxinos G., and Watson C. The Rat Brain in Stereotaxic Coordinates. 2nd ed. (1986), Academic Press, Sydney
22. Reilly S., and Trifunovic R. Lateral parabrachial nucleus lesions in the rat: aversive and appetitive gustatory conditioning. Brain Res. Bull. 52 (2000) 269-278
23. Ruch S., Grigson P.S., and Norgren R. The role of lateral hypothalamic neurons in conditioned taste aversion and sodium appetite. Soc. Neurosci. Abstr. 23 (1997) 1349
24. Sano H., and Yokoi M. Striatal medium spiny neurons terminate in a distinct region in the lateral hypothalamic area and do not directly innervate orexin/hypocretin- or melanin-concentrating hormone-containing neurons. J. Neurosci. 27 (2007) 6948-6955
25. Scott T.R., and Verhagen J.V. Taste as a factor in the management of nutrition. Nutrition 16 (2000) 874-885
26. Shiraishi T. Noradrenergic neurons modulate lateral hypothalamic chemical and electrical stimulation-induced feeding by sated rats. Brain Res. Bull. 27 (1991) 347-351
27. Smith D.V., and Travers J.B. A metric for the breadth of tuning of gustatory neurons. Chem. Senses Flavor 4 (1979) 215-229
28. Smith D.V., and Li C.S. GABA-mediated corticofugal inhibition of taste-responsive neurons in the nucleus of the solitary tract. Brain Res. 858 (2000) 408-415
29. Touzani K., and Velley L. Ibotenic acid lesion of the lateral hypothalamus increases preference and aversion thresholds for saccharin and alters the morphine modulation of taste. Pharmacol. Biochem. Behav. 36 (1990) 585-591
30. Touzani K., Taghzouti K., and Velley L. Cellular organization of lateral hypothalamic efferents to the central amygdaloid nucleus of the rat. Neuro Rep. 7 (1996) 517-520
31. Vasudev R., Gentil C.G., and Covian M.R. Effect of electrical and chemical stimulation of the lateral hypothalamus on taste preferences. Braz. J. Med. Biol. Res. 18 (1985) 3-14
32. Voshart K., and Der Kooy D.V. The organization of the efferent projections of the parabrachial nucleus to the forebrain in the rat: a retrograde fluorescent double-labeling study. Brain Res. 212 (1981) 271-286