Nucleophilic difluoromethylation and difluoromethylenation of aldehydes and ketones using diethyl difluoromethylphosphonate

Tetrahedron

Volumn 64, Issue 49, 2008, Pages 10977-10985

  Beier, Petr ^a   Alexandrova, Anastasia V ^a   Zibinsky, Mikhail ^b   Surya Prakash, G K ^b  

^a INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Difluoromethylation; Difluoromethylenation; Nucleophilic addition; Phosphonate

Indexed keywords

ALDEHYDE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 2 (NAPHTHALEN 1 YL)ETHYLPHOSPHONATE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 2 PHENYLETHYL PHOSPHONATE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 2 PHENYLPROPYL PHOSPHANATE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 2,2 DIPHENYLETHYL PHOSPHANATE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 4 PHENYLBUT 3 ENYLPHOSPHANONATE; DIETHYL 1,1 DIFLUORO 2 HYDROXY 4 PHENYLBUTYL PHOSPHANATE; DIETHYL 1,1DIFLUORO 2 HYDROXY 2 METHYLPROPYL PHOSPHANATE; DIETHYL 2 (4 CHLOROPHENYL) 1,1 DIFLUORO 2 HYDROXYETHYLPHOSPHONATE; DIETHYL 2 (4(DIMETHYLAMINO)PHENYL) 1,1 DIFLUORO 2 HYDROXYETHYLPHOSPHONATE; DIETHYL DIFLUORO(1 HYDROXYCYCLOHEXYL) METHYL PHOSPHONATE; DIETHYL DIFLUOROMETHYL PHOSPHONATE; KETONE; PHOSPHONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; FLUORINATION; FLUORINE NUCLEAR MAGNETIC RESONANCE; METHANOLYSIS; METHYLATION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; QUANTUM YIELD; STEREOCHEMISTRY;

EID: 54549108722     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2008.10.006     Document Type: Article

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