Mycophenolate Mofetil for the Treatment of Uveitis

American Journal of Ophthalmology

Volumn 146, Issue 5, 2008, Pages

  Teoh, Stephen C ^a   Hogan, Aideen C ^a   Dick, Andrew D ^a   Lee, Richard W J ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; AZATHIOPRINE; CYCLOSPORIN; METHOTREXATE; METHYLPREDNISOLONE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISONE; TACROLIMUS;

ABNORMAL LABORATORY RESULT; ADOLESCENT; ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANEMIA; ARTICLE; BILIRUBIN BLOOD LEVEL; CHILD; DRUG DOSE REDUCTION; DRUG EFFICACY; DRUG HYPERSENSITIVITY; DRUG SAFETY; DRUG TOLERANCE; DRUG WITHDRAWAL; EYE INFLAMMATION; FATIGUE; FEMALE; GASTROINTESTINAL SYMPTOM; HEADACHE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; LIVER FUNCTION TEST; LYMPHOCYTOPENIA; LYMPHOMA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETINITIS; SEPSIS; SIDE EFFECT; UVEITIS;

EID: 54449094449     PISSN: 00029394     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ajo.2008.03.004     Document Type: Article

References (28)

1. Jabs D.A., Rosenbaum J.T., Foster C.S., et al. Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel. Am J Ophthalmol 130 (2000) 492-513
2. Imrie F.R., and Dick A.D. Nonsteroidal drugs for the treatment of noninfectious posterior and intermediate uveitis. Curr Opin Ophthalmol 18 (2007) 212-219
3. Okada A.A. Noninfectious uveitis: a scarcity of randomized clinical trials. Arch Ophthalmol 123 (2005) 682-683
4. Standardization of Uveitis Nomenclature (SUN) Working Group. Standardization of uveitis nomenclature for reporting clinical data: results of the first international workshop. Am J Ophthalmol 140 (2005) 509-516
5. McCune W.J. Mycophenolate mofetil for lupus nephritis. N Engl J Med 353 (2005) 2282-2284
6. Ekberg H., Tedesco-Silva H., Demirbas A., et al. Reduced exposure to calcineurin inhibitors in renal transplantation. N Engl J Med 357 (2007) 2562-2575
7. Allison A.C. Mechanisms of action of mycophenolate mofetil. Lupus 14 (2005) S2-S8
8. Chanaud N.P., Vistica B.P., Eugui E., Nussenblatt R.B., Allison A.C., and Gery I. Inhibition of experimental autoimmune uveoretinitis by mycophenolate mofetil, an inhibitor of purine metabolism. Exp Eye Res 61 (1995) 429-434
9. Dick A.D., Kreutzer B., Laliotou B., and Forrester J.V. Effects of mycophenolate mofetil on nasal mucosal tolerance induction. Invest Ophthalmol Vis Sci 39 (1998) 835-840
10. Kilmartin D.J., Forrester J.V., and Dick A.D. Rescue therapy with mycophenolate mofetil in refractory uveitis. Lancet 352 (1998) 35-36
11. Larkin G., and Lightman S. Mycophenolate mofetil: A useful immunosuppressive in inflammatory eye disease. Ophthalmology 106 (1999) 370-374
12. Zierhut M., Stubiger N., Aboalchamat W., Landenberger H., Bialasiewicz A.A., and Engelmann K. [Immunosuppressive therapy with mycophenolate mofetil (CellCept) in treatment of uveitis]. Ophthalmologe 98 (2001) 647-651
13. Greiner K., Varikkara M., Santiago C., and Forrester J.V. [Efficiency of mycophenolate mofetil in the treatment of intermediate and posterior uveitis]. Ophthalmologe 99 (2002) 691-694
14. Lau C.H., Comer M., and Lightman S. Long-term efficacy of mycophenolate mofetil in the control of severe intraocular inflammation. Clin Experiment Ophthalmol 31 (2003) 487-491
15. Baltatzis S., Tufail F., Yu E.N., Vredeveld C.M., and Foster C.S. Mycophenolate mofetil as an immunomodulatory agent in the treatment of chronic ocular inflammatory disorders. Ophthalmology 110 (2003) 1061-1065
16. Llinares-Tello F., Hernandez-Prats C., Munoz-Ruiz C., Selva-Otaolaurruchi J., and Ordovas-Baines J.P. Monitoring trough plasma concentrations of mycophenolate mofetil in patients with uveitis. J Clin Pharm Ther 29 (2004) 53-58
17. Thorne J.E., Jabs D.A., Qazi F.A., Nguyen Q.D., Kempen J.H., and Dunn J.P. Mycophenolate mofetil therapy for inflammatory eye disease. Ophthalmology 112 (2005) 1472-1477
18. Siepmann K., Huber M., Stubiger N., Deuter C., and Zierhut M. Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis. Graefes Arch Clin Exp Ophthalmol 244 (2006) 788-794
19. Choudhary A., Harding S.P., Bucknall R.C., and Pearce I.A. Mycophenolate mofetil as an immunosuppressive agent in refractory inflammatory eye disease. J Ocul Pharmacol Ther 22 (2006) 168-175
20. Doycheva D., Deuter C., Stuebiger N., Biester S., and Zierhut M. Mycophenolate mofetil in the treatment of uveitis in children. Br J Ophthalmol 91 (2007) 180-184
21. Jabs D.A. Improving the reporting of clinical case series. Am J Ophthalmol 139 (2005) 900-905
22. Bach M. Author Response: Numerical imputation for low vision states [electronic letter]. Invest Ophthalmol Vis Sci 26 July 2007 (2008). http://www.iovs.org/cgi/eletters/47/3/1236 Accessed: January 13
23. Kaplan E., and Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 53 (1958) 457-481
24. Hogan A.C., McAvoy C.E., Dick A.D., and Lee R.W. Long-term efficacy and tolerance of tacrolimus for the treatment of uveitis. Ophthalmology 114 (2007) 1000-1006
25. BenEzra D., Forrester J.V., Nussenblatt R.B., et al. Uveitis scoring system (1991), Springer-Verlag, Berlin, Germany
26. Rosenbaum J.T. Biologics and Behcet's: disease diversity and trial design. Ocul Immunol Inflamm 15 (2007) 61-62
27. Dick A.D. Immune mechanisms of uveitis: insights into disease pathogenesis and treatment. Int Ophthalmol Clin 40 (2000) 1-18
28. Zwerner J., and Fiorentino D. Mycophenolate mofetil. Dermatol Ther 20 (2007) 229-238