Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol

Biochemical and Biophysical Research Communications

Volumn 377, Issue 1, 2008, Pages 23-28

  Murayama, Kazutaka ^a,b   Kato Murayama, Miyuki ^b   Mishima, Chiemi ^b   Akasaka, Ryogo ^b   Shirouzu, Mikako ^b   Fukui, Yasuhisa ^c   Yokoyama, Shigeyuki ^b,d  

^a TOHOKU UNIVERSITY   (Japan)

^b RIKEN YOKOHAMA INSTITUTE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

Author keywords

Complex structure; Dimerization; Membrane targeting; Phosphatidylinositol; Pleckstrin homology domain

Indexed keywords

BRUTON TYROSINE KINASE; DIACYLGLYCEROL; DIBUTYLYLPHOSPHATIDYLINOSITOL 3,4,5 TRIPHOSPHATE; PHOSPHATIDYLINOSITOL; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DIMERIZATION; HYDROGEN BOND; MOLECULAR RECOGNITION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

AMINO ACID SEQUENCE; BLOOD PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHATIDYLINOSITOL PHOSPHATES; PHOSPHOPROTEINS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-TYROSINE KINASES;

EID: 54449091168     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2008.09.055     Document Type: Article

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