Preneoplastic lesion growth driven by the death of adjacent normal stem cells

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 39, 2008, Pages 15034-15039

  Chao, Dennis L ^a   Thomas Eck, J ^b   Brash, Douglas E ^c   Maley, Carlo C ^d   Georg Luebeck, E ^a  

^a Fred Hutchinson Cancer Research Center   (United States)

^b RUTGERS UNIVERSITY   (United States)

^c YALE CANCER CENTER   (United States)

^d WISTAR INSTITUTE   (United States)

Author keywords

Clonal expansion; Computer simulation; Skin cancer; TP53; UVB

Indexed keywords

PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL DIVISION; CELL GROWTH; CELL KILLING; COMPUTER SIMULATION; CONTROLLED STUDY; EPIDERMIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STEM CELL; ULTRAVIOLET B RADIATION; ANIMAL; BIOLOGICAL MODEL; CELL CLONE; GENETICS; PATHOLOGY; PRECANCER; RADIATION EXPOSURE; SKIN TUMOR; ULTRAVIOLET RADIATION;

ANIMALS; APOPTOSIS; CLONE CELLS; COMPUTER SIMULATION; EPIDERMIS; MICE; MODELS, BIOLOGICAL; PRECANCEROUS CONDITIONS; SKIN NEOPLASMS; STEM CELLS; TUMOR SUPPRESSOR PROTEIN P53; ULTRAVIOLET RAYS;

EID: 54449090902     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0802211105     Document Type: Article

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