Mitochondria damage checkpoint in apoptosis and genome stability

FEMS Yeast Research

Volumn 5, Issue 2, 2004, Pages 127-132

  Singh, Keshav K ^a  

^a Rm 247 Roswell Pk Cancer I ^*  (United States)

Author keywords

Apoptosis; ATP; DNA damage; DNA repair; Genomic instability; Mitochondrial damage; Oxidative damage; Oxidative stress

Indexed keywords

APOPTOSIS; BIOLOGICAL MONITORING; CELL DAMAGE; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; CORRELATION ANALYSIS; DNA METABOLISM; DNA RECOMBINATION; DNA REPAIR; FUNGAL GENE; GENE MUTATION; GENE OVEREXPRESSION; MITOCHONDRIAL RESPIRATION; MOLECULAR GENETICS; MOLECULAR INTERACTION; MOLECULAR MECHANICS; NONHUMAN; SACCHAROMYCES CEREVISIAE; SHORT SURVEY; SIGNAL TRANSDUCTION;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; DNA REPAIR; DNA REPLICATION; DNA, MITOCHONDRIAL; GENES, CDC; GENOME, FUNGAL; HUMANS; MITOCHONDRIA; OXIDATIVE STRESS; SACCHAROMYCES CEREVISIAE;

MAMMALIA;

EID: 5444260157     PISSN: 15671356     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.femsyr.2004.04.008     Document Type: Short Survey

References (37)

1. Singh K.K. Mitochondrial DNA Mutations in Aging, Disease, and Cancer. 1998;Springer, New York, NY
2. Ravagnan L., Roumier T., Kroemer G. Mitochondria, the killer organelles and their weapons. J. Cell. Physiol. 192:2002;131-137
3. Williamson D. The curious history of yeast mitochondrial DNA. Nat. Rev. Genet. 3:2002;475-481
4. Sickmann A., Reinders J., Wagner Y., Joppich C., Zahedi R., Meyer H.E., Schonfisch B., Perschil I., Chacinska A., Guiard B., Rehling P., Pfanner N., Meisinger C. The proteome of Saccharomyces cerevisiae mitochondria. Proc. Natl. Acad. Sci. USA. 100:2003;13207-13212
5. Singh K.K. Mitochondrial me and the Mitochondrion journal. Mitochondrion. 1:2000;1-2
6. Naviaux R., Singh K.K. Manipulations of the mitochondrial germ line must be openly debated and followed up. Nature. 413:2001;347
7. Singh K.K., Luccy B.M., Zullo S.J. Mitochondria, oxidative stress and mitochondrial diseases. Oxidative Stress and Aging: Advances in Basic Science, Diagnostics, and Intervention. 2003;452-466 World Scientific Publishing Company, New York, NY
8. Kim G., Sikder H., Singh K.K. A colorimetric method identifies the vulnerability of mitochondria to oxidative damage. Mutagenesis. 17:2002;375-381
9. Delsite R.D., Kachhap S., Anbazhagan R., Gabrielson E., Singh K.K. Nuclear genes involved in mitochondria-to-nucleus communication in breast cancer cells. Mol. Cancer. 1:2002;6-15
10. Richter C. Do mitochondrial DNA fragments promote cancer and aging? FEBS Lett. 241:1988;1-5
11. Yakes F.M., Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc. Natl. Acad. Sci. USA. 94(2):1997;514-519
12. Jaruga P., Dizdaroglu M. Repair of products of oxidative DNA base damage in human cells. Nucleic Acid Res. 24:1996;1389-1394
13. Rassmussen L., Singh K.K. Genetic integrity of mitochondrial genome. Mitochondrial DNA Mutations in Aging, Disease, and Cancer. 1998;Springer, New York, NY
14. Rasmussen A.K., Chatterjee A., Rasmussen L.R., Singh K.K. Mitochondria-mediated-mutator phenotype in Saccharomyces cerevisiae. Nucleic Acid Res. 31:2003;3909-3917
15. Samper E., Nicholls D.G., Melov S. Mitochondrial oxidative stress causes chromosomal instability of mouse embryonic fibroblasts. Aging Cell. 2:2003;277-285
16. Liu L., Trimarchi J.R., Smith P.J., Keefe D.L. Mitochondrial dysfunction leads to telomere attrition and genomic instability. Aging Cell. 1:2002;40-46
17. Traut T.W. Physiological concentrations of purines and pyrimidines. Mol. Cell Biochem. 140:1994;1-22
18. Loffler M., Jockel J., Schuster G., Becker C. Dihydroorotat-ubiquinone oxidoreductase links mitochondria in the biosynthesis of pyrimidine nucleotides. Mol. Cell Biochem. 174:1997;125-129
19. Song S., Wheeler L.J., Mathews C.K. Deoxyribonucleotide pool imbalance stimulates deletions in HeLa cell mitochondrial DNA. J. Biol. Chem. 278:2003;43893-43896
20. Popescu N.C. Sister chromatid exchange formation in mammalian cells is modulated by deoxyribonucleotide pool imbalance. Somat. Cell Mol. Genet. 25:1999;101-108
21. Gangi-Peterson L., Sorscher D.H., Reynolds J.W., Kepler T.B., Mitchell B.S. Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination. J. Clin. Invest. 103:1999;833-841
22. Melnyk S., Pogribna M., Miller B.J., Basnakian A.G., Pogribny I.P., James S.J. Uracil misincorporation, DNA strand breaks, and gene amplification are associated with tumorigenic cell transformation in folate deficient/repleted Chinese hamster ovary cells. Cancer Lett. 146:1999;35-44
23. 0-ATP synthase dimeric complex does not require the ATPase inhibitor protein, Inh1. J. Biol. Chem. 277:2002;39289-39295
24. Hong S., Pedersen P.L. ATP synthase of yeast: structural insight into the different inhibitory potencies of two regulatory peptides and identification of a new potential regulator. Arch. Biochem. Biophys. 405:2002;38-43
25. Weinert T. DNA damage and checkpoint pathways: molecular anatomy and interactions with repair. Cell. 94:1998;555-558
26. Sweet S., Singh G. Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpoints. Cancer Res. 55:1995;5164-5167
27. Sekito T., Thornton J., Butow R.A. Mitochondria-to-nuclear signaling is regulated by the subcellular localization of the transcription factors Rtg1p and Rtg3p. Mol. Biol. Cell. 11:2000;2103-2115
28. Ruprich-Robert G., Zickler D., Berteaux-Lecellier V., Velot C., Picard M. Lack of mitochondrial citrate synthase discloses a new meiotic checkpoint in a strict aerobe. EMBO J. 21:2002;6440-6451
29. Lefai E., Fernandez-Moreno M.A., Alahari A., Kaguni L.S., Garesse R. Differential regulation of the catalytic and accessory subunit genes of Drosophila mitochondrial DNA polymerase. J. Biol. Chem. 275:2000;33123-33133
30. Yokomori K. SMC protein complexes and the maintenance of chromosome integrity. Curr. Top. Microbiol. Immunol. 274:2003;79-112
31. Park S.Y., Chang I., Kang S.W., Park S.H., Singh K.K., Lee M.S. Resistance of mitochondrial DNA-depleted cells against cell death: Role of mitochondrial superoxide dismutase. J. Biol. Chem. 279:2004;7512-7520
32. Delsite R.L., Rasmussen L.J., Rasmussen A.K., Kalen A., Goswami P.C., Singh K.K. Mitochondrial impairment is accompanied by impaired DNA repair in the nucleus. Mutagenesis. 18:2003;497-503
33. Jin C., Reed J.C. Yeast and apoptosis. Nat. Rev. Mol. Cell. Biol. 3:2002;453-459
34. Madeo F., Engelhardt S., Herker E., Lehmann N., Maldener C., Proksch A., Wissing S., Fröhlich K.U. Apoptosis in yeast: a new model system with applications in cell biology and medicine. Curr. Genet. 41:2002;208-216
35. Ludovico P., Rodrigues F., Almeida A., Silva M.T., Barrientos A., Côrte-Real M. Cytochrome. c release and mitochondria involvement in programmed cell death induced by acetic acid in Saccharomyces cerevisiae Mol. Biol. Cell. 13:2002;2598-2606
36. Singh K.K., Rasmussen A.K., Rasmussen L.J. Genome wide analysis of signal transducers and regulators of mitochondrial dysfunction in Saccharomyces cerevisiae. Ann. New York Acad. Sci. 1011:2004;284-298
37. Hartwill L.H., Weinert T.A. Checkpoints: control that ensure the order of cell cycle events. Science. 246:1989;629-634