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Volumn 6, Issue 3, 2004, Pages 303-311

Stem cell therapy for Parkinson's disease

Author keywords

Differentiation; Dopamine; Embryonic stem cell; Neural progenitor; Neurogenesis; Ventral mesencephalon

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; 4 AMINOBUTYRIC ACID; BRAIN DERIVED NEUROTROPHIC FACTOR; CYTOKINE; EPIDERMAL GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; FIBROBLAST GROWTH FACTOR 8; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; INTERLEUKIN 1; INTERLEUKIN 11; LEUKEMIA INHIBITORY FACTOR; LEVODOPA; RETINOIC ACID; SONIC HEDGEHOG PROTEIN; TRANSFORMING GROWTH FACTOR ALPHA;

EID: 5444238034     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (4)

References (113)
  • 1
    • 0023835638 scopus 로고
    • Transplantation of fetal substantia nigra and adrenal medulla to the caudate putamen in two patients with Parkinson's disease
    • Madrazo I, Leon V, Torres C, et al. Transplantation of fetal substantia nigra and adrenal medulla to the caudate putamen in two patients with Parkinson's disease. N Engl J Med. 1988;318:51.
    • (1988) N Engl J Med , vol.318 , pp. 51
    • Madrazo, I.1    Leon, V.2    Torres, C.3
  • 2
    • 0021988433 scopus 로고
    • Transplantation of adrenal medullary tissue to striatum in parkinsonism
    • Backlund E, Granberg P, Hamberger B, et al. Transplantation of adrenal medullary tissue to striatum in parkinsonism. J Neurosurg. 1985;62:169-173.
    • (1985) J Neurosurg , vol.62 , pp. 169-173
    • Backlund, E.1    Granberg, P.2    Hamberger, B.3
  • 3
    • 0019855957 scopus 로고
    • Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour
    • Freed WJ, Molikisa JM, Spool E, et al. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour. Nature. 1981;292:351-352.
    • (1981) Nature , vol.292 , pp. 351-352
    • Freed, W.J.1    Molikisa, J.M.2    Spool, E.3
  • 4
    • 0018695489 scopus 로고
    • Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants
    • Bjorklund A, Stenevi U. Reconstruction of the nigrostriatal dopamine pathway by intracerebral nigral transplants. Brain Res. 1979;177:555-560.
    • (1979) Brain Res , vol.177 , pp. 555-560
    • Bjorklund, A.1    Stenevi, U.2
  • 5
    • 0018778418 scopus 로고
    • Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system
    • Perlow MJ, Freed WJ, Hoffer BJ, et al. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science. 1979;204:643-647.
    • (1979) Science , vol.204 , pp. 643-647
    • Perlow, M.J.1    Freed, W.J.2    Hoffer, B.J.3
  • 6
    • 0003057732 scopus 로고
    • Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum
    • Dunnett S, Bjorklund A, eds. New York, NY: Raven Press
    • Brundin P, Duan W, Sauer H. Functional effects of mesencephalic dopamine neurons and adrenal chromaffin cells grafted to the rodent striatum. In: Dunnett S, Bjorklund A, eds. Functional Neural Transplantation. Vol 2. New York, NY: Raven Press; 1994:9-46.
    • (1994) Functional Neural Transplantation , vol.2 , pp. 9-46
    • Brundin, P.1    Duan, W.2    Sauer, H.3
  • 7
    • 0028220186 scopus 로고
    • Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway
    • Annett LE, Martel FL, Rogers DC, et al. Behavioral assessment of the effects of embryonic nigral grafts in marmosets with unilateral 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol. 1994;125:228-246.
    • (1994) Exp Neurol , vol.125 , pp. 228-246
    • Annett, L.E.1    Martel, F.L.2    Rogers, D.C.3
  • 8
    • 0018825573 scopus 로고
    • Reinnervation of the denervated striatum by substantia nigra transplants: Functional consequences as revealed by pharmacological and sensorimotor testing
    • Bjorklund A, Dunnett SB, Stenevi V, Lewis ME, Iversen SD. Reinnervation of the denervated striatum by substantia nigra transplants: functional consequences as revealed by pharmacological and sensorimotor testing. Brain Res. 1980;199:307-333.
    • (1980) Brain Res , vol.199 , pp. 307-333
    • Bjorklund, A.1    Dunnett, S.B.2    Stenevi, V.3    Lewis, M.E.4    Iversen, S.D.5
  • 9
    • 0023716805 scopus 로고
    • Behavioral and anatomical correlates of immunologically induced rejection of nigral xenografts
    • Carder RK, Snyder-Keller AM, Lund RD. Behavioral and anatomical correlates of immunologically induced rejection of nigral xenografts. J Comp Neurol. 1988;277:391-402.
    • (1988) J Comp Neurol , vol.277 , pp. 391-402
    • Carder, R.K.1    Snyder-Keller, A.M.2    Lund, R.D.3
  • 10
    • 0023813332 scopus 로고
    • Graft-derived recovery from 6-OHDA lesions: Specificity of ventral mesencephalic graft tissue
    • Dunnett SB, Hernandez TD, Summerfield A, Jones GH, Arbuthnott G. Graft-derived recovery from 6-OHDA lesions: specificity of ventral mesencephalic graft tissue. Exp Brain Res. 1988;71:411-424.
    • (1988) Exp Brain Res , vol.71 , pp. 411-424
    • Dunnett, S.B.1    Hernandez, T.D.2    Summerfield, A.3    Jones, G.H.4    Arbuthnott, G.5
  • 11
    • 0031890991 scopus 로고    scopus 로고
    • In vivo PET imaging in rat of dopamine terminals reveals functional neural transplants
    • Brownell AL, Livni E, Galpern W, Isacson O. In vivo PET imaging in rat of dopamine terminals reveals functional neural transplants. Ann Neurol. 1998;43:387-390.
    • (1998) Ann Neurol , vol.43 , pp. 387-390
    • Brownell, A.L.1    Livni, E.2    Galpern, W.3    Isacson, O.4
  • 12
    • 0025261943 scopus 로고
    • Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year
    • Freed CR, Breeze RE, Rosenberg NL, et al. Transplantation of human fetal dopamine cells for Parkinson's disease. Results at 1 year. Arch Neurol. 1990;47:505-512.
    • (1990) Arch Neurol , vol.47 , pp. 505-512
    • Freed, C.R.1    Breeze, R.E.2    Rosenberg, N.L.3
  • 13
    • 0024241136 scopus 로고
    • Fetal dopamine-rich mesencephalic grafts in Parkinson's disease
    • Lindvall O, Rehncrona S, Gustavii B, et al. Fetal dopamine-rich mesencephalic grafts in Parkinson's disease. Lancet. 1988;2:1483-1484.
    • (1988) Lancet , vol.2 , pp. 1483-1484
    • Lindvall, O.1    Rehncrona, S.2    Gustavii, B.3
  • 14
    • 18344417278 scopus 로고    scopus 로고
    • Neural transplantation for the treatment of Parkinson's disease
    • Bjorklund A, Dunnett SB, Brundin P, et al. Neural transplantation for the treatment of Parkinson's disease. Lancet Neurol. 2003;2:437-445.
    • (2003) Lancet Neurol , vol.2 , pp. 437-445
    • Bjorklund, A.1    Dunnett, S.B.2    Brundin, P.3
  • 15
    • 0036307190 scopus 로고    scopus 로고
    • Dyskinesias following neural transplantation in Parkinson's disease
    • Hagell P, Piccini P, Bjorklund A, et al. Dyskinesias following neural transplantation in Parkinson's disease. Nat Neurosci. 2002;5:627-628.
    • (2002) Nat Neurosci , vol.5 , pp. 627-628
    • Hagell, P.1    Piccini, P.2    Bjorklund, A.3
  • 16
    • 0033767269 scopus 로고    scopus 로고
    • Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts
    • Piccini P, Lindvall O, Bjorklund A, et al. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Ann Neurol. 2000;48:689-695.
    • (2000) Ann Neurol , vol.48 , pp. 689-695
    • Piccini, P.1    Lindvall, O.2    Bjorklund, A.3
  • 17
    • 0033934144 scopus 로고    scopus 로고
    • Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease
    • Brundin P, Pogarell O, Hagell P, et al. Bilateral caudate and putamen grafts of embryonic mesencephalic tissue treated with lazaroids in Parkinson's disease. Brain. 2000;123(Pt 7):1380-1390.
    • (2000) Brain , vol.123 , Issue.PART 7 , pp. 1380-1390
    • Brundin, P.1    Pogarell, O.2    Hagell, P.3
  • 18
    • 0033491121 scopus 로고    scopus 로고
    • Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient
    • Piccini P, Brooks DJ, Bjorklund A, et al. Dopamine release from nigral transplants visualized in vivo in a Parkinson's patient. Nat Neurosci. 1999;2:1137-1140.
    • (1999) Nat Neurosci , vol.2 , pp. 1137-1140
    • Piccini, P.1    Brooks, D.J.2    Bjorklund, A.3
  • 19
    • 0032692348 scopus 로고    scopus 로고
    • Sequential bilateral transplantation in Parkinson's disease: Effects of the second graft
    • Hagell P, Schrag A, Piccini P, et al. Sequential bilateral transplantation in Parkinson's disease: effects of the second graft. Brain. 1999;122(Pt 6):1121-1132.
    • (1999) Brain , vol.122 , Issue.PART 6 , pp. 1121-1132
    • Hagell, P.1    Schrag, A.2    Piccini, P.3
  • 20
    • 0030834093 scopus 로고    scopus 로고
    • Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease
    • Wenning GK, Odin P, Morrish P, et al. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Ann Neurol. 1997;42:95-107.
    • (1997) Ann Neurol , vol.42 , pp. 95-107
    • Wenning, G.K.1    Odin, P.2    Morrish, P.3
  • 21
    • 0027356279 scopus 로고
    • Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism
    • Widner H, Tertrud J, Rehncrona S, et al. Fifteen months' follow-up on bilateral embryonic mesencephalic grafts in two cases of severe MPTP-induced parkinsonism. Adv Neurol. 1993;60:729-733.
    • (1993) Adv Neurol , vol.60 , pp. 729-733
    • Widner, H.1    Tertrud, J.2    Rehncrona, S.3
  • 22
    • 0026458624 scopus 로고
    • Bilateral fetal mesencephalic grafting in two patients with severe parkinsonism induced by MPTP
    • Widner H, Tertrud J, Rehncrona S, et al. Bilateral fetal mesencephalic grafting in two patients with severe parkinsonism induced by MPTP. N Engl J Med. 1992;327:1556-1563.
    • (1992) N Engl J Med , vol.327 , pp. 1556-1563
    • Widner, H.1    Tertrud, J.2    Rehncrona, S.3
  • 23
    • 0026533881 scopus 로고
    • 18F]-6-L-fluorodopa studies in two patients with putamina implants
    • 18F]-6-L-fluorodopa studies in two patients with putamina implants. Ann Neurol. 1992;31:166-173.
    • (1992) Ann Neurol , vol.31 , pp. 166-173
    • Sawle, G.V.1    Bloomfield, P.M.2    Bjorklund, A.3
  • 24
    • 0026584525 scopus 로고
    • Transplantation of fetal dopamine neurons in Parkinson's disease: 1-Year clinical and neurophysiological observations in two patients with putaminal implants
    • Lindvall O, Widner H, Rehncrona S, et al. Transplantation of fetal dopamine neurons in Parkinson's disease: 1-year clinical and neurophysiological observations in two patients with putaminal implants. Ann Neurol. 1992;31:155-165.
    • (1992) Ann Neurol , vol.31 , pp. 155-165
    • Lindvall, O.1    Widner, H.2    Rehncrona, S.3
  • 25
    • 0025058215 scopus 로고
    • Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease
    • Lindvall O, Brundin P, Widner H, et al. Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease. Science. 1990;247:574-577.
    • (1990) Science , vol.247 , pp. 574-577
    • Lindvall, O.1    Brundin, P.2    Widner, H.3
  • 26
    • 0025180670 scopus 로고
    • Neural transplantation in Parkinson's disease: The Swedish experience
    • Lindvall O, Rehncrona S, Brundin P, et al. Neural transplantation in Parkinson's disease: the Swedish experience. Prog Brain Res. 1990;82:729-734.
    • (1990) Prog Brain Res , vol.82 , pp. 729-734
    • Lindvall, O.1    Rehncrona, S.2    Brundin, P.3
  • 27
    • 0024362054 scopus 로고
    • Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease: A detailed account of methodology and a 6-month follow-up
    • Lindvall O, Brundin P, Rehncrona S, et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease: a detailed account of methodology and a 6-month follow-up. Arch Neurol. 1989;46:615-631.
    • (1989) Arch Neurol , vol.46 , pp. 615-631
    • Lindvall, O.1    Brundin, P.2    Rehncrona, S.3
  • 28
    • 0028941084 scopus 로고
    • Implantation of fetal tissue for the management of Parkinson's disease: A technical note
    • Discussion. 1995;36:1047-1048
    • Breeze RE, Wells TH Jr, Freed CR. Implantation of fetal tissue for the management of Parkinson's disease: a technical note. Neurosurgery. 1995;36:1044-1047. Discussion. 1995;36:1047-1048.
    • (1995) Neurosurgery , vol.36 , pp. 1044-1047
    • Breeze, R.E.1    Wells Jr., T.H.2    Freed, C.R.3
  • 29
    • 0026443974 scopus 로고
    • Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease
    • Freed CR, Breeze RE, Rosenberg NL, et al. Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease. N Engl J Med. 1992;327:1549-1555.
    • (1992) N Engl J Med , vol.327 , pp. 1549-1555
    • Freed, C.R.1    Breeze, R.E.2    Rosenberg, N.L.3
  • 30
    • 0026560671 scopus 로고
    • Improved drug responsiveness following fetal tissue implant for Parkinson's disease
    • Freed CR, Rosenberg NL, Schneck SA, Breeze RE. Improved drug responsiveness following fetal tissue implant for Parkinson's disease. Neurochem Int. 1992;20(suppl):321S-327S.
    • (1992) Neurochem Int , vol.20 , Issue.SUPPL.
    • Freed, C.R.1    Rosenberg, N.L.2    Schneck, S.A.3    Breeze, R.E.4
  • 31
    • 0035826089 scopus 로고    scopus 로고
    • Transplantation of embryonic dopamine neurons for severe Parkinson's disease
    • Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. N Engl J Med. 2001;344:710-719.
    • (2001) N Engl J Med , vol.344 , pp. 710-719
    • Freed, C.R.1    Greene, P.E.2    Breeze, R.E.3
  • 32
    • 0042837887 scopus 로고    scopus 로고
    • A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease
    • Olanow CW, Goetz CG, Koldower JH, et al. A double-blind controlled trial of bilateral fetal nigral transplantation in Parkinson's disease. Ann Neurol. 2003;54:403-414.
    • (2003) Ann Neurol , vol.54 , pp. 403-414
    • Olanow, C.W.1    Goetz, C.G.2    Koldower, J.H.3
  • 33
    • 0037133311 scopus 로고    scopus 로고
    • Will embryonic stem cells be a useful source of dopamine neurons for transplant into patients with Parkinson's disease?
    • Freed CR. Will embryonic stem cells be a useful source of dopamine neurons for transplant into patients with Parkinson's disease? Proc Natl Acad Sci USA. 2002;99:1755-1757.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 1755-1757
    • Freed, C.R.1
  • 34
    • 0036096908 scopus 로고    scopus 로고
    • Stem cells in the treatment of Parkinson's disease
    • Arenas E. Stem cells in the treatment of Parkinson's disease. Brain Res Bull. 2002;57:795-808.
    • (2002) Brain Res Bull , vol.57 , pp. 795-808
    • Arenas, E.1
  • 35
    • 0038049538 scopus 로고    scopus 로고
    • The production and use of cells as therapeutic agents in neurodegenerative diseases
    • Isacson O. The production and use of cells as therapeutic agents in neurodegenerative diseases. Lancet Neurol. 2003;2:417-424.
    • (2003) Lancet Neurol , vol.2 , pp. 417-424
    • Isacson, O.1
  • 36
    • 0019826665 scopus 로고
    • Establishment in culture of pluripotential cells from mouse embryos
    • Evans MJ, Kaufman MH. Establishment in culture of pluripotential cells from mouse embryos. Nature. 1981;292:154-156.
    • (1981) Nature , vol.292 , pp. 154-156
    • Evans, M.J.1    Kaufman, M.H.2
  • 37
    • 0001007610 scopus 로고
    • Isolation of a pleuripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells
    • Martin GR. Isolation of a pleuripotent cell line from early mouse embryos cultured in medium conditioned by teratocarcinoma stem cells. Proc Natl Acad Sci U S A. 1981;78:7634-7638.
    • (1981) Proc Natl Acad Sci U S A , vol.78 , pp. 7634-7638
    • Martin, G.R.1
  • 38
    • 0033110102 scopus 로고    scopus 로고
    • Embryonic stem cells for medicine
    • Pederson RA. Embryonic stem cells for medicine. Sci Am. 1999;April:68-73.
    • (1999) Sci Am , vol.APRIL , pp. 68-73
    • Pederson, R.A.1
  • 39
    • 0017330056 scopus 로고
    • Histologic analyses of experimental tumors from mouse blastocyst-derived cell lines
    • Sherman MI, Miller RA, Richter CB. Histologic analyses of experimental tumors from mouse blastocyst-derived cell lines. J Natl Cancer Inst. 1977;58:993-1002.
    • (1977) J Natl Cancer Inst , vol.58 , pp. 993-1002
    • Sherman, M.I.1    Miller, R.A.2    Richter, C.B.3
  • 41
    • 10744229091 scopus 로고    scopus 로고
    • Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice
    • Barberi T, Klivenyi P, Calingasan NY, et al. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol. 2003;21:1200-1207.
    • (2003) Nat Biotechnol , vol.21 , pp. 1200-1207
    • Barberi, T.1    Klivenyi, P.2    Calingasan, N.Y.3
  • 42
    • 0035025619 scopus 로고    scopus 로고
    • Direct neural fate specification from embryonic stem cells. A primitive mammalian neural stem cell stage acquired through a default mechanism
    • Tropepe V, Hitoshi S, Sirard C, et al. Direct neural fate specification from embryonic stem cells. A primitive mammalian neural stem cell stage acquired through a default mechanism. Neuron. 2001;30:65-78.
    • (2001) Neuron , vol.30 , pp. 65-78
    • Tropepe, V.1    Hitoshi, S.2    Sirard, C.3
  • 43
    • 0036546980 scopus 로고    scopus 로고
    • Neural induction, the default model and embryonic stem cells
    • Munoz-Sanjuan I, Brivanlou AH. Neural induction, the default model and embryonic stem cells. Nat Rev Neurosci. 2002;3:271-280.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 271-280
    • Munoz-Sanjuan, I.1    Brivanlou, A.H.2
  • 44
    • 0031936039 scopus 로고    scopus 로고
    • Blastula-derived stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation
    • Deacon T, Dinsmou J, Costantini LC, Ratliff J, Isacson O. Blastula-derived stem cells can differentiate into dopaminergic and serotonergic neurons after transplantation. Exp Neurol. 1998;149:28-41.
    • (1998) Exp Neurol , vol.149 , pp. 28-41
    • Deacon, T.1    Dinsmou, J.2    Costantini, L.C.3    Ratliff, J.4    Isacson, O.5
  • 45
    • 0037133163 scopus 로고    scopus 로고
    • Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model
    • Bjorklund LM, Sanchez-Pernaute R, Chung S, et al. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci U S A. 2002;99:2344-2349.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 2344-2349
    • Bjorklund, L.M.1    Sanchez-Pernaute, R.2    Chung, S.3
  • 46
    • 0034044317 scopus 로고    scopus 로고
    • Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells
    • Lee SH, Lumelsky N, Studer L, Averback JM, McKay RD. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol. 2000;18:675-679.
    • (2000) Nat Biotechnol , vol.18 , pp. 675-679
    • Lee, S.H.1    Lumelsky, N.2    Studer, L.3    Averback, J.M.4    McKay, R.D.5
  • 47
    • 0036835342 scopus 로고    scopus 로고
    • Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons
    • Chung S, Sonntag KC, Andersson T, et al. Genetic engineering of mouse embryonic stem cells by Nurr1 enhances differentiation and maturation into dopaminergic neurons. Eur J Neurosci. 2002;16:1829-1838.
    • (2002) Eur J Neurosci , vol.16 , pp. 1829-1838
    • Chung, S.1    Sonntag, K.C.2    Andersson, T.3
  • 48
    • 0037019332 scopus 로고    scopus 로고
    • Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease
    • Kim JH, Averback JM, Rodriguez-Gomez JA, et al. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature. 2002;418:50-56.
    • (2002) Nature , vol.418 , pp. 50-56
    • Kim, J.H.1    Averback, J.M.2    Rodriguez-Gomez, J.A.3
  • 49
    • 0037226224 scopus 로고    scopus 로고
    • Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: Improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells
    • Nishimura F, Yoshikawa M, Kanda S, et al. Potential use of embryonic stem cells for the treatment of mouse parkinsonian models: improved behavior by transplantation of in vitro differentiated dopaminergic neurons from embryonic stem cells. Stem Cells. 2003;21:171-180.
    • (2003) Stem Cells , vol.21 , pp. 171-180
    • Nishimura, F.1    Yoshikawa, M.2    Kanda, S.3
  • 50
    • 0033638174 scopus 로고    scopus 로고
    • Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity
    • Kawasaki H, Mizuseki K, Nishikawa S, et al. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron. 2000;28:31-40.
    • (2000) Neuron , vol.28 , pp. 31-40
    • Kawasaki, H.1    Mizuseki, K.2    Nishikawa, S.3
  • 51
    • 0035957754 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer
    • Wakayama T, Tabar V, Rodriguez I, et al. Differentiation of embryonic stem cell lines generated from adult somatic cells by nuclear transfer. Science. 2001;292:740-743.
    • (2001) Science , vol.292 , pp. 740-743
    • Wakayama, T.1    Tabar, V.2    Rodriguez, I.3
  • 52
    • 0037313844 scopus 로고    scopus 로고
    • Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture
    • Ying QL, Stavridis M, Griffiths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol. 2003;21:183-186.
    • (2003) Nat Biotechnol , vol.21 , pp. 183-186
    • Ying, Q.L.1    Stavridis, M.2    Griffiths, D.3    Li, M.4    Smith, A.5
  • 54
    • 0029776359 scopus 로고    scopus 로고
    • Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts
    • Thomson JA, Kalishman J, Golos TG, et al. Pluripotent cell lines derived from common marmoset (Callithrix jacchus) blastocysts. Biol Reprod. 1996;55:254-259.
    • (1996) Biol Reprod , vol.55 , pp. 254-259
    • Thomson, J.A.1    Kalishman, J.2    Golos, T.G.3
  • 55
    • 0032491416 scopus 로고    scopus 로고
    • Embryonic stem cells derived from human blastocysts
    • Thomson JA, Itskovitz-Eldor J, Shapiro SS, et al. Embryonic stem cells derived from human blastocysts. Science. 1998;282:1145-1147.
    • (1998) Science , vol.282 , pp. 1145-1147
    • Thomson, J.A.1    Itskovitz-Eldor, J.2    Shapiro, S.S.3
  • 56
    • 0037022299 scopus 로고    scopus 로고
    • Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity
    • Kawasaki H, Suemori H, Mizuseki K, et al. Generation of dopaminergic neurons and pigmented epithelia from primate ES cells by stromal cell-derived inducing activity. Proc Natl Acad Sci U S A. 2002;99:1580-1585.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 1580-1585
    • Kawasaki, H.1    Suemori, H.2    Mizuseki, K.3
  • 57
    • 0141483048 scopus 로고    scopus 로고
    • Nonhuman primate parthenogenetic stem cells
    • Vrana KE, Hipp JD, Goss AM, et al. Nonhuman primate parthenogenetic stem cells. Proc Natl Acad Sci USA. 2003;100(suppl 1):11911-11916.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.SUPPL. 1 , pp. 11911-11916
    • Vrana, K.E.1    Hipp, J.D.2    Goss, A.M.3
  • 58
    • 0035200623 scopus 로고    scopus 로고
    • In vitro differentiation of transplantable neural precursors from human embryonic stem cells
    • Zhang SC, Wernig M, Duncan ID, Brustle O, Thomson JA. In vitro differentiation of transplantable neural precursors from human embryonic stem cells. Nat Biotechnol. 2001;19:1129-1133.
    • (2001) Nat Biotechnol , vol.19 , pp. 1129-1133
    • Zhang, S.C.1    Wernig, M.2    Duncan, I.D.3    Brustle, O.4    Thomson, J.A.5
  • 59
    • 0035690493 scopus 로고    scopus 로고
    • Enrichment of neurons and neural precursors from human embryonic stem cells
    • Carpenter MK, Inokuma MS, Denham J, et al. Enrichment of neurons and neural precursors from human embryonic stem cells. Exp Neurol. 2001;172:383-397.
    • (2001) Exp Neurol , vol.172 , pp. 383-397
    • Carpenter, M.K.1    Inokuma, M.S.2    Denham, J.3
  • 60
    • 0035203881 scopus 로고    scopus 로고
    • Neural progenitors from human embryonic stem cells
    • Reubinoff BE, Itsykson P, Turetsky T, et al. Neural progenitors from human embryonic stem cells. Nat Biotechnol. 2001;19:1134-1140.
    • (2001) Nat Biotechnol , vol.19 , pp. 1134-1140
    • Reubinoff, B.E.1    Itsykson, P.2    Turetsky, T.3
  • 61
    • 0026699762 scopus 로고
    • Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture
    • Matsui Y, Zsebo K, Hogan BL. Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture. Cell. 1992;70:841-847.
    • (1992) Cell , vol.70 , pp. 841-847
    • Matsui, Y.1    Zsebo, K.2    Hogan, B.L.3
  • 62
    • 0032506231 scopus 로고    scopus 로고
    • Derivation of pluripotent stem cells from cultured human primordial germ cells
    • Shamblott MJ, Axelman J, Wang S, et al. Derivation of pluripotent stem cells from cultured human primordial germ cells. Proc Natl Acad Sci USA. 1998;95:13726-13731.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 13726-13731
    • Shamblott, M.J.1    Axelman, J.2    Wang, S.3
  • 63
    • 0038236733 scopus 로고    scopus 로고
    • Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury
    • Kerr DA, Llado J, Shamblott MJ, et al. Human embryonic germ cell derivatives facilitate motor recovery of rats with diffuse motor neuron injury. J Neurosci. 2003;23:5131-5140.
    • (2003) J Neurosci , vol.23 , pp. 5131-5140
    • Kerr, D.A.1    Llado, J.2    Shamblott, M.J.3
  • 64
    • 0030448423 scopus 로고    scopus 로고
    • Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons
    • Johe KK, Hazel TG, Muller T, Dugish-Diordjevic MM, McKay RD. Single factors direct the differentiation of stem cells from the fetal and adult central nervous system. Functions of basic fibroblast growth factor and neurotrophins in the differentiation of hippocampal neurons. Genes Dev. 1996;10:3129-3140.
    • (1996) Genes Dev , vol.10 , pp. 3129-3140
    • Johe, K.K.1    Hazel, T.G.2    Muller, T.3    Dugish-Diordjevic, M.M.4    McKay, R.D.5
  • 65
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds BA, Weiss S. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science. 1992;255:1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 66
    • 0033152408 scopus 로고    scopus 로고
    • Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain
    • Daadi MM, Weiss S. Generation of tyrosine hydroxylase-producing neurons from precursors of the embryonic and adult forebrain. J Neurosci. 1999;19:4484-4497.
    • (1999) J Neurosci , vol.19 , pp. 4484-4497
    • Daadi, M.M.1    Weiss, S.2
  • 67
    • 0032837298 scopus 로고    scopus 로고
    • In vitro expansion of a multipotent population of human neural progenitor cells
    • Carpenter MK, Cui X, Hu ZY, et al. In vitro expansion of a multipotent population of human neural progenitor cells. Exp Neurol. 1999;158:265-278.
    • (1999) Exp Neurol , vol.158 , pp. 265-278
    • Carpenter, M.K.1    Cui, X.2    Hu, Z.Y.3
  • 68
    • 0031265935 scopus 로고    scopus 로고
    • Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease
    • Svendsen CN, Caldwell MA, Shen J, et al. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Exp Neurol. 1997;148:135-146.
    • (1997) Exp Neurol , vol.148 , pp. 135-146
    • Svendsen, C.N.1    Caldwell, M.A.2    Shen, J.3
  • 69
    • 0036434257 scopus 로고    scopus 로고
    • Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat
    • Yang M, Stull ND, Berk MA, Snyder EY, Iacovitti L. Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat. Exp Neurol. 2002;177:50-60.
    • (2002) Exp Neurol , vol.177 , pp. 50-60
    • Yang, M.1    Stull, N.D.2    Berk, M.A.3    Snyder, E.Y.4    Iacovitti, L.5
  • 70
    • 0036844019 scopus 로고    scopus 로고
    • Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons
    • Ourednik J, Ourednik V, Lynch WP, Schachner M, Snyder EY. Neural stem cells display an inherent mechanism for rescuing dysfunctional neurons. Nat Biotechnol. 2002;20:1103-10.
    • (2002) Nat Biotechnol , vol.20 , pp. 1103-1110
    • Ourednik, J.1    Ourednik, V.2    Lynch, W.P.3    Schachner, M.4    Snyder, E.Y.5
  • 71
    • 0031002024 scopus 로고    scopus 로고
    • Dopamine neuron agenesis in Nurr1-deficient mice
    • Zetterstrom RH, Solomin L, Jansson L, et al. Dopamine neuron agenesis in Nurr1-deficient mice. Science. 1997;276:248-250.
    • (1997) Science , vol.276 , pp. 248-250
    • Zetterstrom, R.H.1    Solomin, L.2    Jansson, L.3
  • 72
    • 0032980340 scopus 로고    scopus 로고
    • Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes
    • Wagner J, Akerud P, Castro DS, et al. Induction of a midbrain dopaminergic phenotype in Nurr1-overexpressing neural stem cells by type 1 astrocytes. Nat Biotechnol. 1999;17:653-659.
    • (1999) Nat Biotechnol , vol.17 , pp. 653-659
    • Wagner, J.1    Akerud, P.2    Castro, D.S.3
  • 73
    • 0022636849 scopus 로고
    • Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins
    • Lee VMY, Andrews PW. Differentiation of NTERA-2 clonal human embryonal carcinoma cells into neurons involves the induction of all three neurofilament proteins. J Neurosci. 1986;6:514-521.
    • (1986) J Neurosci , vol.6 , pp. 514-521
    • Lee, V.M.Y.1    Andrews, P.W.2
  • 74
    • 0031005327 scopus 로고    scopus 로고
    • Expression of tyrosine hydroxylase in newly differentiated neurons from a human cell line (hNT)
    • Iacovitti L, Stull ND. Expression of tyrosine hydroxylase in newly differentiated neurons from a human cell line (hNT). Neuroreport. 1997;8:1471-1474.
    • (1997) Neuroreport , vol.8 , pp. 1471-1474
    • Iacovitti, L.1    Stull, N.D.2
  • 76
    • 0033669223 scopus 로고    scopus 로고
    • In vitro and in vivo characterization of hNT neuron neurotransmitter phenotypes
    • Saporta S, Willing AE, Colina LO, et al. In vitro and in vivo characterization of hNT neuron neurotransmitter phenotypes. Brain Res Bull. 2000;53:263-268.
    • (2000) Brain Res Bull , vol.53 , pp. 263-268
    • Saporta, S.1    Willing, A.E.2    Colina, L.O.3
  • 77
    • 0034051525 scopus 로고    scopus 로고
    • Intrastriatal and intranigral grafting of hNT neurons in the 6-OHDA rat model of Parkinson's disease
    • Baker KA, Hong M, Sadi D, Mendez I. Intrastriatal and intranigral grafting of hNT neurons in the 6-OHDA rat model of Parkinson's disease. Exp Neurol. 2000;162:350-360.
    • (2000) Exp Neurol , vol.162 , pp. 350-360
    • Baker, K.A.1    Hong, M.2    Sadi, D.3    Mendez, I.4
  • 78
    • 0033928986 scopus 로고    scopus 로고
    • Improved survival of embryonic porcine dopaminergic neurons in coculture with a conditionally immortalized GDNF-producing hippocampal cell line
    • Meyer M, Johansen J, Gramsbergen JB, Johansen TE, Zimmer J. Improved survival of embryonic porcine dopaminergic neurons in coculture with a conditionally immortalized GDNF-producing hippocampal cell line. Exp Neurol. 2000;164:82-93.
    • (2000) Exp Neurol , vol.164 , pp. 82-93
    • Meyer, M.1    Johansen, J.2    Gramsbergen, J.B.3    Johansen, T.E.4    Zimmer, J.5
  • 79
    • 0037106092 scopus 로고    scopus 로고
    • Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons
    • Ostenfeld T, Tai YT, Martin P, et al. Neurospheres modified to produce glial cell line-derived neurotrophic factor increase the survival of transplanted dopamine neurons. J Neurosci Res. 2002;69:955-965.
    • (2002) J Neurosci Res , vol.69 , pp. 955-965
    • Ostenfeld, T.1    Tai, Y.T.2    Martin, P.3
  • 80
    • 0035887595 scopus 로고    scopus 로고
    • Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease
    • Akerud P, CAnals JM, Snyder EY, Arenas E. Neuroprotection through delivery of glial cell line-derived neurotrophic factor by neural stem cells in a mouse model of Parkinson's disease. J Neurosci. 2001;21:8108-8118.
    • (2001) J Neurosci , vol.21 , pp. 8108-8118
    • Akerud, P.1    Canals, J.M.2    Snyder, E.Y.3    Arenas, E.4
  • 81
    • 0036432028 scopus 로고    scopus 로고
    • Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease
    • Akerud P, HOm PC, Castelo-Branco G, et al. Persephin-overexpressing neural stem cells regulate the function of nigral dopaminergic neurons and prevent their degeneration in a model of Parkinson's disease. Mol Cell Neurosci. 2002;21:205-222.
    • (2002) Mol Cell Neurosci , vol.21 , pp. 205-222
    • Akerud, P.1    Hom, P.C.2    Castelo-Branco, G.3
  • 82
    • 0038249170 scopus 로고    scopus 로고
    • Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease
    • Gill SS, Patel NK, Hotton GR, et al. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nat Med. 2003;9:589-595.
    • (2003) Nat Med , vol.9 , pp. 589-595
    • Gill, S.S.1    Patel, N.K.2    Hotton, G.R.3
  • 83
    • 33644684826 scopus 로고    scopus 로고
    • Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats
    • Studer L, Tabar V, McKay RD. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci. 1998;1:290-295.
    • (1998) Nat Neurosci , vol.1 , pp. 290-295
    • Studer, L.1    Tabar, V.2    McKay, R.D.3
  • 84
    • 0034307725 scopus 로고    scopus 로고
    • Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen
    • Studer L, Csete M, Lee SH, et al. Enhanced proliferation, survival, and dopaminergic differentiation of CNS precursors in lowered oxygen. J Neurosci. 2000;20:7377-7383.
    • (2000) J Neurosci , vol.20 , pp. 7377-7383
    • Studer, L.1    Csete, M.2    Lee, S.H.3
  • 85
    • 0035172717 scopus 로고    scopus 로고
    • Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors
    • Yan J, Studer L, McKay RD. Ascorbic acid increases the yield of dopaminergic neurons derived from basic fibroblast growth factor expanded mesencephalic precursors. J Neurochem. 2001;76:307-311.
    • (2001) J Neurochem , vol.76 , pp. 307-311
    • Yan, J.1    Studer, L.2    McKay, R.D.3
  • 87
    • 0032196206 scopus 로고    scopus 로고
    • Survival of expanded dopaminergic precursors is critical for clinical trials
    • Brundin P, Bjorklund A. Survival of expanded dopaminergic precursors is critical for clinical trials. Nat Neurosci. 1998;1:537.
    • (1998) Nat Neurosci , vol.1 , pp. 537
    • Brundin, P.1    Bjorklund, A.2
  • 88
    • 0032007097 scopus 로고    scopus 로고
    • Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines
    • Ling ZD, Potter ED, Lipton JW, Carvey PM. Differentiation of mesencephalic progenitor cells into dopaminergic neurons by cytokines. Exp Neurol. 1998;149:411-423.
    • (1998) Exp Neurol , vol.149 , pp. 411-423
    • Ling, Z.D.1    Potter, E.D.2    Lipton, J.W.3    Carvey, P.M.4
  • 89
    • 0032918328 scopus 로고    scopus 로고
    • Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons
    • Potter ED, Ling ZD, Carvey PM. Cytokine-induced conversion of mesencephalic-derived progenitor cells into dopamine neurons. Cell Tiss Res. 1999;296:235-246.
    • (1999) Cell Tiss Res , vol.296 , pp. 235-246
    • Potter, E.D.1    Ling, Z.D.2    Carvey, P.M.3
  • 90
    • 0034845508 scopus 로고    scopus 로고
    • A clonal line of mesencephalic progenitor cells converted to dopamine neurons by hematopoietic cytokines: A source of cells for transplantation in Parkinson's disease
    • Carvey PM, Ling ZD, Sortwell CE, et al. A clonal line of mesencephalic progenitor cells converted to dopamine neurons by hematopoietic cytokines: a source of cells for transplantation in Parkinson's disease. Exp Neurol. 2001;171:98-108.
    • (2001) Exp Neurol , vol.171 , pp. 98-108
    • Carvey, P.M.1    Ling, Z.D.2    Sortwell, C.E.3
  • 91
    • 0034871846 scopus 로고    scopus 로고
    • Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells
    • Storch A, Paul G, Csete M, et al. Long-term proliferation and dopaminergic differentiation of human mesencephalic neural precursor cells. Exp Neurol. 2001;170:317-325.
    • (2001) Exp Neurol , vol.170 , pp. 317-325
    • Storch, A.1    Paul, G.2    Csete, M.3
  • 92
    • 0037198603 scopus 로고    scopus 로고
    • The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro
    • Riaz SS, Jauniaux E, Stern GM, Bradford HF. The controlled conversion of human neural progenitor cells derived from foetal ventral mesencephalon into dopaminergic neurons in vitro. Brain Res Dev Brain Res. 2002;136:27-34.
    • (2002) Brain Res Dev Brain Res , vol.136 , pp. 27-34
    • Riaz, S.S.1    Jauniaux, E.2    Stern, G.M.3    Bradford, H.F.4
  • 93
    • 0001159822 scopus 로고
    • Are new neurons formed in the brains of adult mammals?
    • Altman J. Are new neurons formed in the brains of adult mammals? Science. 1962;135:1127-1128.
    • (1962) Science , vol.135 , pp. 1127-1128
    • Altman, J.1
  • 95
    • 0029610078 scopus 로고
    • Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain
    • Gage FH, Coates PW, PAlmer TD. Survival and differentiation of adult neuronal progenitor cells transplanted to the adult brain Proc Natl Acad Sci USA. 1995;92:11679-11883.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 11679-11883
    • Gage, F.H.1    Coates, P.W.2    Palmer, T.D.3
  • 96
    • 0030438734 scopus 로고    scopus 로고
    • The adult rat hippocampus contains primordial neural stem cells
    • Palmer TD, Takahashi J, Gage FH. The adult rat hippocampus contains primordial neural stem cells. Mol Cell Neurosci. 1997;8:389-404.
    • (1997) Mol Cell Neurosci , vol.8 , pp. 389-404
    • Palmer, T.D.1    Takahashi, J.2    Gage, F.H.3
  • 98
    • 14344274193 scopus 로고    scopus 로고
    • In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain
    • Fallon J, reid S, Kinyamu R, et al. In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain. Proc Natl Acad Sci U S A. 2000;97:14686-14691.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 14686-14691
    • Fallon, J.1    Reid, S.2    Kinyamu, R.3
  • 99
    • 0038037721 scopus 로고    scopus 로고
    • Evidence for neurogenesis in the adult mammalian substantia nigra
    • Zhao M, Momma S, Delfani K, et al. Evidence for neurogenesis in the adult mammalian substantia nigra. Proc Natl Acad Sci U S A. 2003;100:7925-7930.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 7925-7930
    • Zhao, M.1    Momma, S.2    Delfani, K.3
  • 100
    • 0036703488 scopus 로고    scopus 로고
    • The adult substantia nigra contains progenitor cells with neurogenic potential
    • Lie DC, Dziewczapolski G, Willhoite AR, et al. The adult substantia nigra contains progenitor cells with neurogenic potential. J Neurosci. 2002;22:6639-6649.
    • (2002) J Neurosci , vol.22 , pp. 6639-6649
    • Lie, D.C.1    Dziewczapolski, G.2    Willhoite, A.R.3
  • 101
    • 0025358695 scopus 로고
    • Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases
    • Iacopino AM, Christakos S. Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases. Proc Natl Acad Sci U S A. 1990;87:4078-4082.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 4078-4082
    • Iacopino, A.M.1    Christakos, S.2
  • 102
    • 0025196543 scopus 로고
    • Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K
    • Yamada T, McGeer PL, Baimbridge KG, McGeer EG. Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K. Brain Res. 1990;526:303-307.
    • (1990) Brain Res , vol.526 , pp. 303-307
    • Yamada, T.1    McGeer, P.L.2    Baimbridge, K.G.3    McGeer, E.G.4
  • 103
    • 0026616873 scopus 로고
    • Calbindin-D28k in the basal ganglia of patients with parkinsonism
    • Ito H, Goto S, Sakamoto S, Hirano A. Calbindin-D28k in the basal ganglia of patients with parkinsonism. Ann Neurol. 1992;32:543-550.
    • (1992) Ann Neurol , vol.32 , pp. 543-550
    • Ito, H.1    Goto, S.2    Sakamoto, S.3    Hirano, A.4
  • 104
    • 0026638825 scopus 로고
    • Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease
    • Gibb WR. Melanin, tyrosine hydroxylase, calbindin and substance P in the human midbrain and substantia nigra in relation to nigrostriatal projections and differential neuronal susceptibility in Parkinson's disease. Brain Res. 1992;581:283-291.
    • (1992) Brain Res , vol.581 , pp. 283-291
    • Gibb, W.R.1
  • 105
    • 0013774096 scopus 로고
    • Localization of monoamines in the lower brain stem
    • Dahlstrom A, Fuxe K. Localization of monoamines in the lower brain stem. Experientia. 1964;20:398-399.
    • (1964) Experientia , vol.20 , pp. 398-399
    • Dahlstrom, A.1    Fuxe, K.2
  • 106
    • 0023481972 scopus 로고
    • The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems
    • Gerfen CR, Herkenham M, Thibault J. The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems. J Neurosci. 1987;7:3915-3934.
    • (1987) J Neurosci , vol.7 , pp. 3915-3934
    • Gerfen, C.R.1    Herkenham, M.2    Thibault, J.3
  • 107
    • 0032865590 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry
    • Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry [see comments]. Brain. 1999;122(Pt 8):1421-1436.
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1421-1436
    • Damier, P.1    Hirsch, E.C.2    Agid, Y.3    Graybiel, A.M.4
  • 108
    • 0030839090 scopus 로고    scopus 로고
    • Medial fetal ventral mesencephalon: A preferred source for dopamine neuron grafts
    • Costantini LC, Lin L, Isacson O. Medial fetal ventral mesencephalon: a preferred source for dopamine neuron grafts. Neuroreport. 1997;8:2253-2257.
    • (1997) Neuroreport , vol.8 , pp. 2253-2257
    • Costantini, L.C.1    Lin, L.2    Isacson, O.3
  • 109
    • 0030924631 scopus 로고    scopus 로고
    • Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA-lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons
    • Haque N, LeBlanc C, Isacson O. Differential dissection of the rat E16 ventral mesencephalon and survival and reinnervation of the 6-OHDA-lesioned striatum by a subset of aldehyde dehydrogenase-positive TH neurons. Cell Transplant. 1997;6:239-248.
    • (1997) Cell Transplant , vol.6 , pp. 239-248
    • Haque, N.1    LeBlanc, C.2    Isacson, O.3
  • 110
    • 0033638456 scopus 로고    scopus 로고
    • Cell and synaptic replacement therapy for Parkinson's disease: Current status and future directions
    • Bjorklund L, Herlihy D, Isacson O. Cell and synaptic replacement therapy for Parkinson's disease: current status and future directions. Neurosci News. 2000;3:6-12.
    • (2000) Neurosci News , vol.3 , pp. 6-12
    • Bjorklund, L.1    Herlihy, D.2    Isacson, O.3
  • 111
    • 0036454341 scopus 로고    scopus 로고
    • Regulation of dopamine cell type and transmitter function in fetal and stem cell transplantation for Parkinson's disease
    • Bjorklund LM, Isacson O. Regulation of dopamine cell type and transmitter function in fetal and stem cell transplantation for Parkinson's disease. Prog Brain Res. 2002;138:411-420.
    • (2002) Prog Brain Res , vol.138 , pp. 411-420
    • Bjorklund, L.M.1    Isacson, O.2
  • 112
    • 0037378784 scopus 로고    scopus 로고
    • Toward full restoration of synaptic and terminal function of the dopaminergic system in Parkinson's disease by stem cells
    • Isacson O, Bjorklund LM, Schumacher JM. Toward full restoration of synaptic and terminal function of the dopaminergic system in Parkinson's disease by stem cells. Ann Neurol. 2003;53(3 suppl 1):S135-S148.
    • (2003) Ann Neurol , vol.53 , Issue.3 SUPPL. 1
    • Isacson, O.1    Bjorklund, L.M.2    Schumacher, J.M.3
  • 113
    • 0036394712 scopus 로고    scopus 로고
    • A multiple target neural transplantation strategy for Parkinson's disease
    • Ramachandran AC, Bartlett LE, Mendez IM. A multiple target neural transplantation strategy for Parkinson's disease. Rev Neurosci. 2002;13:243-256.
    • (2002) Rev Neurosci , vol.13 , pp. 243-256
    • Ramachandran, A.C.1    Bartlett, L.E.2    Mendez, I.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.