Pig peripheral blood mononuclear leucocyte subsets are heritable and genetically correlated with performance

Animal

Volumn 2, Issue 11, 2008, Pages 1575-1584

  Clapperton, M ^a   Glass, E J ^a   Bishop, S C ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Heritability; Innate immunity; NK cells; Performance; Pigs

Indexed keywords

SUIDAE;

EID: 54349125963     PISSN: 17517311     EISSN: 1751732X     Source Type: Journal    
DOI: 10.1017/S1751731108002929     Document Type: Article

References (55)

1. + lymphocyte populations? Genes and Immunity 2, 381-387.
2. Cheeseman JH, Kaiser MG and Lamont SJ 2004. Genetic line effect on peripheral blood leucocyte cell surface marker expression in chickens. Poultry Science 83, 911-916.
3. Chen J and Harrison DE 2002. Quantitative trait loci regulating relative lymphocyte proportions in mouse peripheral blood. Blood 99, 561-566.
4. Clapperton M, Bishop SC, Cameron ND and Glass EJ 2005a. Associations of weight gain and food intake with leucocyte sub-sets in Large White pigs. Livestock Production Science 96, 249-260.
5. Clapperton M, Bishop SC, Cameron ND and Glass EJ 2005b. Associations of acute phase protein levels with growth performance and with selection for growth performance in Large White pigs. Animal Science 81, 213-220.
6. Clapperton M, Bishop SC and Glass EJ 2006. Selection for lean growth and food intake leads to correlated changes in innate immune traits in Large White pigs. Animal Science 82, 867-876.
7. Davis WC, Haverson K, Saalmuller A, Yang H, Lunney JK, Hamilton MJ and Pescovitz MD 2001. Analysis of monoclonal antibodies with molecules expressed on gamma delta cells. Veterinary Immunology and Immunopathology 80, 53-62.
8. de Haan G, Bystrykh LV, Weersing E, Dontje B, Geiger H, Ivanova N, Lemischka IR, Vellenga E and Van Zant G 2002. A genetic and genomic analysis identifies a cluster of genes associated with hematopoietic cell turnover. Blood 100, 2056-2062.
9. Denham S, Zwart R, Whitall JTD, Pampusch M, Corteyn AH, Bianchi ATJ, Murtaugh MP, Parkhouse RME, Tlaksova H, Sinkora J, Sinkora M and Rehakova Z 1998. Monoclonal antibodies putatively recognising porcine B cells. Veterinary Immunology and Immunopathology 60, 317-328.
10. Denyer MS, Wileman TE, Stirling CMA, Zuber B and Takamatsu HH 2006. Perforin expression can define CD8 positive lymphocyte subsets in pigs allowing phenotypic and functional analysis in natural killer, cytotoxic T, natural killer T and MHC un-restricted cytotoxic T-cells. Veterinary Immunology and Immunopathology 110, 279-292.
11. Duarte N and Penta-Goncalves C 2001. The MHC locus controls size variations in the CD4 compartment of the mouse thymus. Immunogenetics 53, 662-668.
12. Edfors-Lilja I, Wattrang E, Magnussen U and Fossum C 1994. Genetic variation in parameters reflecting immune competence of swine. Veterinary Immunology and Immunopathology 40, 1-16.
13. Edfors-Lilja I, Wattrang E, Marklund L, Moller M, Andersson-Eklund L, Andersson L and Fossum C 1998. Mapping quantitative trait loci for immune capacity in the pig. Journal of Immunology 161, 829-835.
14. Eurell TE, Bane DP, Hall WF and Schaeffer DJ 1992. Serum haptoglobin concentration as an indicator of weight gain in pigs. Canadian Journal of Veterinary Research 56, 6-9.
15. Evans DM, Frazer IH and Martin NG 1999. Genetic and environmental causes of variation in basal level of blood cells. Twin Research 2, 250-257.
16. Galina-Pantoja L, Mellencamp MA, Bastiaansen J, Cabrera R, Solano-Aguilar G and Lunney JK 2006. Relationship between immune cell phenotypes and pig growth in a commercial farm. Animal Biotechnology 17, 81-98.
17. Gheorgiou M, Mouton D, Lecoeur H, Lagranderie M, Mevel JC and Biozzi G 1985. Resistance of high and low antibody responder lines of mice to the growth of avirulent (BCG) and virulent (H37Rv) strains of mycobacteria. Clinical and Experimental Immunology 59, 177-184.
18. Gilmour AR, Cullis BR, Welham SJ and Thompson R 2004. ASREML: program user manual. VSN International Ltd, Hemel Hempstead, UK.
19. Grellner GF, Fangman TJ, Carroll JA and Wiedmeyer CE 2002. Using serology in combination with acute phase proteins and cortisol to determine stress and immune function of early-weaned pigs. Journal of Swine Health and Production 10, 199-204.
20. Hall MA, Ahmadi KR, Norman P, Snieder H, MacGregor AJ, Vaughan RW, Spector TD and Lanchbury JS 2000. Genetic influence on peripheral blood T lymphocyte levels. Genes and Immunity 1, 423-427.
21. Hall MA, Norman PJ, Thiel B, Tiwari H, Peiffer A, Vaughan RW, Prescott S, Leppert M, Schork NJ and Lanchbury JS 2002. Quantitative trait loci on chromosomes 1, 2, 3, 4, 8, 9, 11, 12 and 18 control variation in levels of T and B lymphocyte sub-populations. American Journal of Human Genetics 70, 1172-1182.
22. Haverson K, Bailey M, Stokes CR, Simon A, LeFlufy L, Banfield G, Chen Z, Hollemweguer E and Ledbetter JA 2001. Monoclonal antibodies raised to human cells - specificity for pig leucocytes. Veterinary Immunology and Immunopathology 80, 175-186.
23. Henryon M, Berg P, Jensen J and Andersen S 2001. Genetic variation for resistance to clinical and sub-clinical diseases exists in growing pigs. Animal Science 73, 375-387.
24. Henryon M, Heegaard PMH, Nielsen J, Berg P and Juul-Madsen HR 2006a. Immunological traits have the potential to improve selection of pigs for resistance to clinical and sub-clinical disease. Animal Science 82, 597-606.
25. Henryon M, Sørenson P, Heegaard PMH, Nielsen J, Berg P and Juul-Madsen HR 2006b. Limited evidence that baseline levels of immunological traits provide useful selection criteria for resistance to clinical and sub-clinical disease in pigs. Proceedings of the 8th World Congress on Genetics Applied to Livestock Production, Communication 15-09.
26. Jayagopala Reddy NR, Wilkie BN, Borgs P and Mallard BA 2000. Cytokines in Mycoplasma hyorhinis-induced arthritis in pigs bred for high and low immune responses. Infection and Immunity 68, 1150-1155.
27. Joling P, Mok KS, de Vries Relingh G, Wever PJ, Cornelis RS, Oskam JP and Henken AM 1993. An evaluation of immune competence in different swine breeds. Veterinary Quarterly 15, 9-15.
28. Lawes Agricultural Trust 1983. GENSTAT. A general statistical program. Numerical Algorithms Group. VSN International Ltd, Hemel Hempstead, UK.
29. + double positive T cells in cynomolgus monkeys. Experimental Animals 52, 309-316.
30. Lodoen MB and Lanier LL 2006. Natural killer cells as an initial defense against pathogens. Current Opinions in Immunology 18, 391-398.
31. Loeffen WLA, Kamp EM, Stockhofe-Zurwieden N, van-Neiuwsadt APKMI, Bongers JH, Hunneman WA, Elbers WRW, Baars J, Nell T and van Zijderveld FG 1999. Survey of infectious agents involved in acute respiratory disease in finishing pigs. Veterinary Record 145, 123-129.
32. + T cells. European Journal of Immunology 27, 189-193.
33. Lyons DT, Freeman AE and Kuck AL 1991. Genetics of health traits in Holstein cattle. Journal of Dairy Science 74, 1092-1100.
34. Mallard BA, Wilkie BN and Kennedy BW 1989. Genetics and other effects on antibody and cell-mediated immune response in swine leucocyte antigen (SLA)-defined miniature pigs. Animal Genetics 20, 167-178.
35. Mallard BA, Wilkie BN, Kennedy BW, Gibson JP and Quinton MJ 1998. Immune responsiveness in swine, eight generations of selection for high and low immune response in Yorkshire pigs. Proceedings of the 6th World Congress on Genetics Applied to Livestock Production, vol. 27, pp. 257-264.
36. Morrison SJ, Qian D, Jerabek L, Thiel BA, Park IK, Ford PS, Kiel MJ, Schork NJ, Weissman IJ and Clarke MF 2002. A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. Journal of Immunology 168, 635-642.
37. Myrick C, DiGuisto R, DeWolfe J, Bowen E, Kappler J, Marrack P and Wakeland EK 2002. Linkage analysis of variations in CD4, CD8 T cell sub-sets between C57BL/6 and DBA/2. Genes and Immunity 3, 144-150.
38. + memory T-helper cells in swine. Journal of Virology 72, 4866-4873.
39. O'Connor GM, Hart OM and Gardiner CM 2005. Putting the natural killer cell in its place. Immunology 117, 1-10.
40. Pallarés FJ, Gómez S, Ramis G, Seva J and Muñoz A 2000. Vaccination against swine enzootic pneumonia in field conditions: effect on clinical, pathological, zoo technical and economic parameters. Veterinary Research 31, 573-582.
41. Parra MD, Fuentes P, Tecles F, Martínez-Subiela S, Martínez JS, Muñoz A and Cerón JJ 2006. Porcine acute phase concentrations in different diseases in field conditions. Journal of Veterinary Medicine Series B 53, 488-493.
42. Pedrini SCB, Acorci MJ, Pinto JGG, Silveira LVA and Oliveira SL 2005. Immune response to the Rhodococcus equi infection in high and low antibody-producing mice (selection IV-A). Microbiology and Immunology 49, 915-923.
43. Petersen HH, Ersboll AK, Jensen CS and Nielsen JP 2002. Serum haptoglobin concentration in Danish slaughter pigs of different health status. Preventive Veterinary Medicine 54, 325-335.
44. Poppe C, Smart N, Khakhria R, Johnson W, Spika J and Prescott J 1998. Salmonella typhimurium DT104: a virulent and drug-resistant pathogen. Canadian Veterinary Journal 39, 559-565.
45. Regula G, Lichtensteiger CA, Mateus-Pinilla NE, Scherba G, Miller GY and Weigel RM 2000. Comparison of serologic testing and slaughter evaluation for assessing the effects of sub-clinical infection on growth in pigs. Journal of American Veterinary Medical Association 217, 888-895.
46. Roberts A, Foote S, Alexander WS, Scott C, Robb L and Metcalf D 1997. Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor. Blood 89, 2736-2744.
47. Saalmuller A, Kuebart G, Hollemweguer E, Chen Z, Neilsen J, Zuckermanm F and Haverson K 2001. Summary of workshop findings for porcine T-lymphocyte-specific monoclonal antibodies. Veterinary Immunology and Immunopathology 80, 35-52.
48. Segalés J, Rosell C and Domingo M 2004. Pathological findings associated with naturally acquired porcine circovirus type 2 associated disease. Veterinary Microbiology 98, 137-149.
49. Snowder GD, Van Vleck LD, Cundiff LV and Bennett GL 2006. Bovine respiratory disease in feedlot cattle: environmental, genetic, and economic factors. Journal of Animal Science 84, 1999-2008.
50. Spurlock ME 1997. Regulation of metabolism and growth during immune challenge, an overview of cytokine function. Journal of Animal Science 75, 1773-1783.
51. Tecles F, Fuentes P, Martínez-Subiela S, Parra MD, Muñoz A and Cerón JJ 2007. Analytical validation of commercially available methods for acute phase protein quantification in pigs. Research in Veterinary Science 83, 133-139.
52. Thacker E, Summerfield A, McCullough K, Dominguez J, Alonso F, Lunney J, Sinkora J and Haverson K 2001. Summary of workshop findings for porcine myelomonocytic markers. Veterinary Immunology and Immunopathology 80, 93-109.
53. Wonigeit K, Washington D and Hundrieser J 1998. Lessons from rat models on the genetic basis of inter-individual differences in lymphocyte phenotype. Transplantation Proceedings 30, 2341-2343.
54. Yang H and Parkhouse RME 1996. Phenotypic classification of porcine lymphocyte populations in blood and lymphoid tissues. Immunology 89, 76-83.
55. Zuckermann FA 1999. Extrathymic CD4/CD8 double positive T cells. Veterinary Immunology and Immunopathology 72, 55-66.