Hip fracture risk and different gene polymorphisms in the Turkish population

Clinics

Volumn 63, Issue 5, 2008, Pages 645-650

  Dinçel, Ercan ^a   Sepici Dinçel, Aylin ^b   Sepici, Vesile ^b   Özsoy, Hakan ^a   Sepici, Behçet ^a  

^a ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b GAZI UNIVERSITY   (Turkey)

Author keywords

Gene polymorphism; Hip fractures risk; Osteoporosis

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE I, ALPHA 1 CHAIN; ESR1 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA; INTERLEUKIN 6; OSTEOPROTEGERIN;

AGED; ARTICLE; BONE DENSITY; CASE CONTROL STUDY; FALLING; FEMALE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HIP FRACTURE; HUMAN; MALE; METHODOLOGY; OSTEOPOROSIS; PHOTON ABSORPTIOMETRY; POLYMERASE CHAIN REACTION; RADIOGRAPHY; RISK ASSESSMENT; TURKEY (REPUBLIC);

ABSORPTIOMETRY, PHOTON; ACCIDENTAL FALLS; AGED; BONE DENSITY; CASE-CONTROL STUDIES; COLLAGEN TYPE I; ESTROGEN RECEPTOR ALPHA; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HIP FRACTURES; HUMANS; INTERLEUKIN-6; MALE; OSTEOPOROSIS; OSTEOPROTEGERIN; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RISK ASSESSMENT; TURKEY;

EID: 54349111650     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.1590/S1807-59322008000500013     Document Type: Article

References (39)

1. Kanis JA, Borgstrom F, De Laet C, Johansson H, Johnell O, Jonsson B, et al. Assessment of fracture risk. Osteoprosis Int. 2005;16:581-89.
2. Taylor BC, Schreiner PJ, Stone KL, Fink HA, Cummings SR, Nevitt MC et al. Long-Term Prediction of Incident Hip Fracture Risk in Elderly White Women: Study of Osteoporotic Fractures. J Am Geriatr Soc. 2004;52:1479-86.
3. Cheng XG, Lowet G, Bonen S, Nicholson HF, Brys P, Nijs J, et al. Assessment of the Strength of Proximal Femur In Vitro: Relationship to Femoral Bone Mineral Density and Femoral Geometry. Bone. 1997;20:213-18.
4. Bergot C, Bousson V, Meunier A, Laval-Jeantet M, Laredo JD. Hip fracture risk and proximal femur geometry from DXA scans. Osteoporos Int. 2002;13:542-50.
5. Kaptoge S, Dalzell N, Loveridge N, Beck TJ, Khaw K, Reeve J. Effects of gender, anthropometric variables, and aging on the evolution of hip strength in men and women aged over 65. Bone. 2003;32:561-70.
6. Zmuda JM, Cauley JA, Ferrell RE. Recent progress in understanding the genetic susceptibility to osteoporosis. Genet Epidemiol. 1999;16:356-67.
7. Ongphiphadhanakul B. Osteoporosis: the role of genetics and the environment. Forum Nutr. 2007;60:158-67.
8. Huang QY, Recker RR, Deng HW. Searching for osteoporosis genes in the post-genome era: progress and challenges. Osteoporos Int. 2003;14:701-5.
9. Roux S. The genetics of osteoporosis. Joint Bone Spine. 2001;68:482-86.
10. McGuigan FE, Armbrecht G, Smith R, Felsenberg D, Reid DM, Ralston SH. Prediction of osteoporotic fractures by bone densitometry and COLIA1 genotyping:a prospective, population-based study in men and women. Osteoporos. Int. 2001;12:91-6.
11. Mann V, Hobson EE, Li B, Stewart TL, Grant SF, Robins SP, et al. A COL1A1 Sp1 binding site polymorphism predisposes to osteoporotic fracture by affecting bone density and quality. J Clin Invest. 2001;107:899-907.
12. Alvarez L, Oriola J, Jo J, Ferró T, Pons F, Peris P, et al. Collagen type I alpha1 gene Sp1 polymorphism in premenopausal women with primary osteoporosis: improved detection of Sp1 binding site poly-morphism in the collagen type 1 gene. Clin Chem. 1999;45:904-06.
13. Keen RW, Woodford-Richens KL, Grant SFA, Ralston SH, Lanchbury JS, Spector TD. Association of polymorphism at the type I collagen (COL1A1) locus with reduced bone mineral density, increased fracture risk, and increased collagen turnover. Arthritis Rheum. 1999;42:285-90.
14. Gennari L, Merlotti D, De Paola V, Calabrò, Becherini L, Martini G, Nuti R, Estrogen Receptor Gene Polymorphisms and the Genetics of Osteoporosis: A HuGE Review. Am. J. Epidemiol. 2005;161:307-20.
15. Shu-Feng Lei, Yan-Bo Wang, Man-Yuan Liu, Xiao-Yang Mo, Hong-Wen Deng. The VDR, COL1A1, PTH, and PTHR1 gene polymorphisms are not associated with bone size and height in Chinese nuclear families. J Bone Miner Metab. 2005;23:501-05.
16. Hofbauer LC, Heufelder AE. Role of receptor activator of nuclear factor-kappaB ligand and osteoprotegerin in bone cell biology. J Mol Med. 2001;79:243-53.
17. Morinaga T, Nakagawa N, Yasuda H, Tsuda E, Higashio K. Cloning and characterization of the gene encoding human osteoprotegerin/osteoclastogenesis inhibitory factor. Eur J Biochem. 1998;254:685-91.
18. Arko B, Prezelj J, Komel R, Kocijancic A, Hudler P, Marc J. Sequence variations in the osteoprotegerin gene promoter in patients with postmenopausal osteoporosis. J Clin Endocrinol Metab. 2002;87:4080-4.
19. Jorgensen HL, Kusk P, Madsen B, Fenger M, Lauritzen JB. Serum osteoprotegerin (OPG) and the A163G polymorphism in the OPG promoter region are related to peripheral measures of bone mass and fracture odds ratios. J Bone Miner Metab. 2004;22:132-8.
20. Langdahl BL, Carstens M, Stenkjaer L, Eriksen EF. Polymorphisms in the osteoprotegerin gene are associated with osteoporotic fractures. J Bone Miner Res. 2002;17:1245-55.
21. Efstathiadou Z, Tsatsoulis A, Ioannidis JP. Association of collagen I alpha 1 Sp1 polymorphism with the risk of prevalent fractures: a metaanalysis. J Bone Miner Res. 2001;16:1586-92.
22. Mann V, Ralston SH. Meta-analysis of COL1A1 Sp1 polymorphism in relation to bone mineral density and osteoporotic fracture. Bone. 2003;32:711-17.
23. Simsek M, Cetin Z, Bilgen T, Taksin O, Luleci G, Keser I. Effects of hormone replacement therapy on bone mineral density in Turkish patients with or without COL1A1 Sp1 binding site polymorphism. J. Obstet. Gynaecol. Res. 2008;34:73-7.
24. Ioannidis JPA, Stavro I, Trikalinos TA, Zois C, Brandi ML, Gennari L, et al. Association of polymorphisms of the estrogen receptor alpha gene with bone mineral density and fracture risk in women: a meta-analysis. J Bone Miner Res. 2002;17:2048-60.
25. Yilmaz A, Menevse S, Erkan FA, Ergun MA, Ilhan NM, Cengel A, Yalcin R. The Relationship of the ESR1 gene polymor hisms with the Presence of coronary artery disease determined by coronary angiography. Genetic Testing. 2007;11:367-71.
26. Duman BS, Tanakol R, Erensoy N, Ozturk M, Yilmazer S. Vitamin D receptor alleles, bone mineral density and turnover in postmenopausal osteoporotic and healthy women. Med Princ Pract. 2004;13:260-6
27. Kahraman H, Duman BS, Alagol F, Tanakol R, Yilmazer S. Lack of association between vitamin D receptor gene polymorphism (BsmI) and osteomalacia. J Bone Miner Metab. 2004;22:39-43.
28. Akcay A, Ozdemir FN, Sezer S, Micozkadioglu H, Arat Z, Atac FB, et al. Association of vitamin D receptor gene polymorphisms with hypercalcemia in peritoneal dialysis patients. Perit Dial Int. 2005;3:52-5.
29. Buyru N, Tezol A, Yosunkaya-Fenerci E, Dalay N. Vitamin D receptor gene polymorphisms in breast cancer. Exp Mol Med. 2003;35:550-5.
30. Kaya TI, Erdal ME, Tursen U, Camdeviren H, Gunduz O, Soylemez F, et al. Association between vitamin D receptor gene polymorphism and psoriasis among the Turkish population. Arch Dermatol Res. 2002;294:286-9.
31. Gunes S, Bilen CY, Kara N, Asci R, Bagci H, Yilmaz AF. Vitamin D receptor gene polymorphisms in patients with urolithiasis. Urol Res.2006;34:47-2.
32. Hansen TS, Abrahamsen B, Henriksen FL, Hermann AP, Jensen LB, Hørder M, et al. Vitamin D receptor alleles do not predict bone mineral density or bone loss in Danish perimenopausal women. Bone. 1998;22:571-75.
33. Marc J, Prezelj J, Komel R, Kocijancic A. Association of vitamin D receptor gene polymorphism with bone mineral density in Slovenian postmenopausal women. Gynecol Endocrinol. 2000;14:60-4.
34. Hauache OM, Lazaretti-Castro M, Andreoni S, Gimeno SG, Brandão C, Ramalho AC, et al. Vitamin D receptor gene polymorphism: correlation with bone mineral density in a Brazilian population with insulin-dependent diabetes mellitus. Osteoporos Int. 1998;8:204-10.
35. Gennari L, Becherini L, Masi L, Mansani R, Gonnelli S, Cepollaro C, Martini S, Montagnani A, Lentini G, Becorpi AM, Brandi ML.Vitamin D and estrogen receptor allelic variants in Italian postmenopausal women: evidence of multiple gene contribution to bone mineral density. J Clin Endocrinol Metab. 1998;83:939-44.
36. Budak F, Goral G, Heper Y, Yilmaz E, Aymak F, Basturk B, Tore O, Ener B, Oral HB. IL-10 and IL-6 gene polymorphisms as potential host susceptibility factors in Brucellosis Cytokine 2007;38:32-36.
37. Moffett SP, Zmuda MJ, Cauley AJ, Stone LK, Nevitt CM, Ensrud EK, Hillier AT, Hochberg CM, Joslyn G, Morin P, Cummings RS for the SOF Research Group. Association of the G-174C Variant in the Interleukin-6 Promoter Region With Bone Loss and Fracture Risk in Older Women. J Bone Miner Res.2004;19:1612-18.
38. Feng D, Ishibashi H, Yamamoto S, Hosoi T, Orimo H, Machida T, et al. Association between bone loss and promoter polymorphism in the IL-6 gene in elderly Japanese women with hip fracture. J Bone Miner Metab. 2003;21:225-8.
39. Ohmori H, Makita Y, Funamizu M, Hirooka K, Hosoi T, Orimo H, et al. Linkage and association analyses of the osteoprotegrin gene locus with human osteoporosis. J Hum Genet. 2002;47:400-6.