A novel human multidrug resistance gene MDR1 variant G571A (G191R) modulates cancer drug resistance and efflux transport

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 2, 2008, Pages 474-481

  Yang, Ziping ^a   Wu, Daniel ^a   Bui, Tot ^a   Ho, Rodney J Y ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DAUNORUBICIN; DOXORUBICIN; ETOPOSIDE; GLYCINE; MULTIDRUG RESISTANCE PROTEIN 1; PACLITAXEL; VINBLASTINE SULFATE; VINCRISTINE SULFATE;

ADULT; AGED; ARTICLE; CANCER RESISTANCE; CONTROLLED STUDY; DNA POLYMORPHISM; DRUG SENSITIVITY; G1199A GENE; G1199T GENE; G571A GENE; GENE; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; LEUKEMIA; MDR1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

ACRIDINES; AGED; AGED, 80 AND OVER; BIOLOGICAL TRANSPORT; CELLS, CULTURED; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; GENOTYPE; HAPLOTYPES; HUMANS; LEUKEMIA; MIDDLE AGED; P-GLYCOPROTEIN; PACLITAXEL; POLYMORPHISM, SINGLE NUCLEOTIDE; TETRAHYDROISOQUINOLINES; VINBLASTINE;

EID: 54349091311     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.138313     Document Type: Article

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