Attentional demands for demonstrating deficits following intrabasalis infusions of 192 IgG-saporin

Behavioural Brain Research

Volumn 195, Issue 2, 2008, Pages 231-238

  Burk, Joshua A ^a   Lowder, Matthew W ^a   Altemose, Kathleen E ^a  

^a The College of William and Mary   (United States)

Author keywords

192 IgG saporin; Acetylcholine; Attention; Basal forebrain; Prefrontal cortex; Vigilance

Indexed keywords

192 IMMUNOGLOBULIN G SAPORIN; IMMUNOTOXIN; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSOCIATION; ATTENTION DISTURBANCE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; DISCRIMINATIVE STIMULUS; HISTOPATHOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASK PERFORMANCE; TRAINING; VISUAL DISCRIMINATION; VISUAL STIMULATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIBODIES, MONOCLONAL; ATTENTION; BASAL NUCLEUS OF MEYNERT; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; CHOLINE O-ACETYLTRANSFERASE; CUES; DISCRIMINATION LEARNING; IMMUNOTOXINS; MALE; MICROINJECTIONS; PATTERN RECOGNITION, VISUAL; PSYCHOMOTOR PERFORMANCE; RATS; RATS, LONG-EVANS; REACTION TIME; RIBOSOME INACTIVATING PROTEINS, TYPE 1; VISUAL PERCEPTION;

EID: 54249142651     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbr.2008.09.006     Document Type: Article

References (38)

1. Arnold H.M., Burk J.A., Hodgson E.M., Sarter M., and Bruno J.P. Differential cortical acetylcholine release in rats performing a sustained attention task versus behavioral control tasks that do not explicitly tax attention. Neuroscience 114 (2002) 451-460
2. Burk J.A. Introduction of a retention interval in a sustained attention task in rats: effects of presenting a visual distracter and increasing the inter-trial interval. Behav Process 67 (2004) 521-531
3. Burk J.A., and Sarter M. Dissociation between the attentional functions mediated via basal forebrain cholinergic and GABAergic neurons. Neuroscience 105 (2001) 899-909
4. Bushnell P.J., Kelly K.L., and Crofton K.M. Effects of toluene inhalation on detection of auditory signals in rats. Neurotoxicol Teratol 16 (1994) 149-160
5. Bushnell P.J. Detection of visual signals by rats: effects of signal intensity, event rate and task type. Behav Process 46 (1999) 141-150
6. Chudasama Y., and Muir J.L. Visual attention in the rat: a role for the prelimbic cortex and thalamic nuclei?. Behav Neurosci 115 (2001) 417-428
7. Dalley J.W., McGaughy J., O'Connell M.T., Cardinal R.N., Levita L., and Robbins T.W. Distinct changes in cortical acetylcholine and noradrenaline efflux during contingent and noncontingent performance of a visual attentional task. J Neurosci 21 (2001) 4908-4914
8. Dalley J.W., Theobald D.E., Bouger P., Chudasama Y., Cardinal R.N., and Robbins T.W. Cortical cholinergic function and deficits in visual attentional performance in rats following 192IgG-saporin-induced lesions of the medial prefrontal cortex. Cereb Cortex 14 (2004) 922-932
9. Echevarria D.J., Brewer A., Burk J.A., Brown S.N., Manuzon H., and Robinson J.K. Construct validity of an operant signal detection task for rats. Behav Brain Res 157 (2005) 283-290
10. Everitt B.J., and Robbins T.W. Central cholinergic systems and cognition. Annu Rev Psychol 48 (1997) 649-684
11. Himmelheber A.M., Sarter M., and Bruno J.P. The effects of manipulations of attentional demand on cortical acetylcholine release. Brain Res Cogn Brain Res 12 (2001) 353-370
12. Koelega H.S., Brinkman J.A., Zwep B., and Verbaten M.N. Dynamic vs static stimuli and their effect on visual vigilance performance. Percept Mot Skills 70 (1990) 823-831
13. McGaughy J., Dalley J.W., Morrison C.H., Everitt B.J., and Robbins T.W. Selective behavioral and neurochemical effects of cholinergic lesions produced by intrabasalis infusions of 192 IgG-saporin on attentional performance in a five-choice serial reaction time task. J Neurosci 22 (2002) 1905-1913
14. McGaughy J., Decker M.W., and Sarter M. Enhancement of sustained attention performance by the nicotinic acetylcholine receptor agonist ABT-418 in intact but not basal forebrain-lesioned rats. Psychopharmacology 144 (1999) 175-182
15. McGaughy J., Everitt B.J., Robbins T.W., and Sarter M. The role of cortical cholinergic afferent projections in cognition: impact of new selective immunotoxins. Behav Brain Res 115 (2000) 251-263
16. McGaughy J., Kaiser T., and Sarter M. Behavioral vigilance following infusions of [192] IgG-saporin into the basal forebrain: selectivity of the behavioral impairment and relation to cortical AChE-positive fiber density. Behav Neurosci 110 (1996) 247-265
17. McGaughy J., and Sarter M. Behavioral vigilance in rats: task validation and effects of age, amphetamine, and benzodiazepine receptor ligands. Psychopharmacology 117 (1995) 340-357
18. McGaughy J., and Sarter M. Sustained attention performance in rats with intracortical infusions of 192 IgG-saporin-induced cortical cholinergic deafferentation: effects of physostigmine and FG 7142. Behav Neurosci 112 (1998) 1519-1525
19. McGaughy J., and Sarter M. Effects of ovariectomy, 192 IgG-saporin-induced cortical cholinergic deafferentation, and administration of estradiol on sustained attention performance in rats. Behav Neurosci 113 (1999) 1216-1232
20. Mesulam M.-M., Mufson E.J., Wainer B.H., and Levey A.I. Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6). Neuroscience 10 (1983) 1185-1201
21. Miner L.A., Ostrander M., and Sarter M. Effects of ibotenic acid-induced loss of neurons in the medial prefrontal cortex of rats on behavioral vigilance: evidence for executive dysfunction. J Psychopharmacol 11 (1997) 169-178
22. Muir J.L., Everitt B.J., and Robbins T.W. AMPA-induced excitotoxic lesions of the basal forebrain: a significant role for the cortical cholinergic system in attentional function. J Neurosci 14 (1994) 2313-2326
23. Newman L.A., and McGaughy J. Cholinergic deafferentation of prefrontal cortex increases sensitivity to cross-modal distractors during a sustained attention task. J Neurosci 28 (2008) 2642-2650
24. Parasuraman R., and Giambra L. Skill development in vigilance: effects of event rate and age. Psychol Aging 6 (1991) 155-169
25. Parasuraman R., and Mouloua M. Interaction of signal discriminability and task type in vigilance decrement. Percept Psychophys 41 (1987) 17-22
26. Parasuraman R., Warm J.S., and Dember W.N. Vigilance: taxonomy and utility. In: Mark L.S., Warm J.S., and Huston R.L. (Eds). Ergonomics and human factors (1987), Springer-Verlag, New York 11-32
27. Parikh V., Kozak R., Martinez V., and Sarter M. Prefrontal acetylcholine release controls cue detection on multiple timescales. Neuron 56 (2007) 141-154
28. Passetti F., Dalley J.W., O'Connell M.T., Everitt B.J., and Robbins T.W. Increased acetylcholine release in the rat medial prefrontal cortex during performance of a visual attentional task. Eur J Neurosci 12 (2000) 3051-3058
29. Robbins T.W. The 5-choice serial reaction time task: behavioural pharmacology and functional neurochemistry. Psychopharmacology 163 (2002) 362-380
30. Robbins T.W., Everitt B.J., Marston H.M., Wilkinson J., Jones G.H., and Page K.J. Comparative effects of ibotenic acid- and quisqualic acid-induced lesions of the substantia innominata on attentional function in the rat: Further implications for the role of the cholinergic neurons of the nucleus basalis in cognitive processes. Behav Brain Res 35 (1989) 221-240
31. Sarter M., and Bruno J.P. Cognitive functions of cortical acetylcholine: toward a unifying hypothesis. Brain Res Brain Res Rev 23 (1997) 28-46
32. Sarter M., Gehring W.J., and Kozak R. More attention must be paid: the neurobiology of attentional effort. Brain Res Rev 51 (2006) 145-160
33. Sarter M., Givens B., and Bruno J.P. The cognitive neuroscience of sustained attention: where top-down meets bottom-up. Brain Res Brain Res Rev 35 (2001) 146-160
34. Sarter M., Hasselmo M.E., Bruno J.P., and Givens B. Unraveling the attentional functions of cortical cholinergic inputs: interactions between signal-driven and cognitive modulation of signal detection. Brain Res Brain Res Rev 48 (2005) 98-111
35. Stichel C.C., and Singer W. Quantitative analysis of the choline acetyltransferase-immunoreactive axonal network in the cat primary visual cortex. J Comp Neurol 258 (1987) 91-98
36. Tago H., Kimura H., and Maeda T. Visualization of detailed acetylcholinesterase fiber and neuron staining in rat brain by a sensitive histochemical procedure. J Histochem Cytochem 34 (1986) 1431-1438
37. Wiley R.G. Neural lesioning with ribosome-inactivating proteins: suicide transport and immunolesioning. Trends Neurosci 15 (1992) 285-290
38. Zar J.H. Biostatistical analysis (1974), Prentice Hall, Englewood Cliffs, NJ