-
1
-
-
72849159485
-
Chromosome studies on normal and leukemic human leukocytes
-
abstract available
-
Nowell PC, Hungerford DA. Chromosome studies on normal and leukemic human leukocytes. J Natl Cancer Inst 1960;25:85-109. No abstract available.
-
(1960)
J Natl Cancer Inst
, vol.25
, Issue.85 -109.
-
-
Nowell, P.C.1
Hungerford, D.A.2
-
2
-
-
0015926591
-
Letter: Deletions of chromosome 7 in haematological disorders. Lancet
-
No abstract available
-
Rowley JD. Letter: Deletions of chromosome 7 in haematological disorders. Lancet. 1973 Dec 15;2:1385-6. No abstract available.
-
(1973)
Dec 15;2
, pp. 1385-1386
-
-
Rowley, J.D.1
-
3
-
-
0021346853
-
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
-
Groffen J, Stephenson JR, Heisterkamp N, de Klein A, Bartram CR, Grosveld G. Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22. Cell 1984;36:93-9.
-
(1984)
Cell
, vol.36
, pp. 93-99
-
-
Groffen, J.1
Stephenson, J.R.2
Heisterkamp, N.3
de Klein, A.4
Bartram, C.R.5
Grosveld, G.6
-
4
-
-
0023483175
-
Molecular lesion in chronic granulocytic leukemia is highly conserved despite ethnic and geographical variation
-
Chan LC, Chen PM, Powles R, Saragas E, Wiedemann LM, Groffen J, Greaves MF. Molecular lesion in chronic granulocytic leukemia is highly conserved despite ethnic and geographical variation. Leukemia 1987;1:486-90.
-
(1987)
Leukemia
, vol.1
, pp. 486-490
-
-
Chan, L.C.1
Chen, P.M.2
Powles, R.3
Saragas, E.4
Wiedemann, L.M.5
Groffen, J.6
Greaves, M.F.7
-
5
-
-
0023133732
-
Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL
-
Clark SS, McLaughlin J, Crist WM, Champlin R, Witte ON. Unique forms of the abl tyrosine kinase distinguish Ph1-positive CML from Ph1-positive ALL. Science 1987;235:85-8.
-
(1987)
Science
, vol.235
, pp. 85-88
-
-
Clark, S.S.1
McLaughlin, J.2
Crist, W.M.3
Champlin, R.4
Witte, O.N.5
-
6
-
-
2542441665
-
The BCR-ABL story: Bench to bed-side and back
-
Review
-
Wong S, Witte ON. The BCR-ABL story: bench to bed-side and back. Annu Rev Immunol 2004;22:247-306. Review.
-
(2004)
Annu Rev Immunol
, vol.22
, pp. 247-306
-
-
Wong, S.1
Witte, O.N.2
-
7
-
-
2542500611
-
-
Calabretta B, Perrotti D. The biology of CML blast crisis. Blood. 2004 Jun 1;103(11):4010-22. Epub 2004 Feb 24. Review.
-
Calabretta B, Perrotti D. The biology of CML blast crisis. Blood. 2004 Jun 1;103(11):4010-22. Epub 2004 Feb 24. Review.
-
-
-
-
8
-
-
0034611661
-
Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia
-
Aricò M, Valsecchi MG, Camitta B, Schrappe M, Chessells J, Baruchel A, et al. Outcome of treatment in children with Philadelphia chromosome-positive acute lymphoblastic leukemia. New Engl J Med 2000;342:998-1006.
-
(2000)
New Engl J Med
, vol.342
, pp. 998-1006
-
-
Aricò, M.1
Valsecchi, M.G.2
Camitta, B.3
Schrappe, M.4
Chessells, J.5
Baruchel, A.6
-
9
-
-
0036493694
-
German Multicenter Trials of Adult Acute Lymphoblastic Leukemia Study Group. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: A prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis
-
Gleissner B, Gökbuget N, Bartram CR, Janssen B, Rieder H, Janssen JW, et al. German Multicenter Trials of Adult Acute Lymphoblastic Leukemia Study Group. Leading prognostic relevance of the BCR-ABL translocation in adult acute B-lineage lymphoblastic leukemia: a prospective study of the German Multicenter Trial Group and confirmed polymerase chain reaction analysis. Blood 2002;99:1536-43.
-
(2002)
Blood
, vol.99
, pp. 1536-1543
-
-
Gleissner, B.1
Gökbuget, N.2
Bartram, C.R.3
Janssen, B.4
Rieder, H.5
Janssen, J.W.6
-
11
-
-
33747154547
-
-
Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F, et al. European LeukemiaNet. Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European Leukemia Net. Blood 2006;108:1809-20. Epub 2006 May 18. Review.
-
Baccarani M, Saglio G, Goldman J, Hochhaus A, Simonsson B, Appelbaum F, et al. European LeukemiaNet. Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European Leukemia Net. Blood 2006;108:1809-20. Epub 2006 May 18. Review.
-
-
-
-
12
-
-
33744463354
-
-
Press RD, Love Z, Tronnes AA, Yang R, Tran T, Mongoue-Tchokote S, et al. BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML. Blood 2006;107:4250-6. Epub 2006 Feb 7.
-
Press RD, Love Z, Tronnes AA, Yang R, Tran T, Mongoue-Tchokote S, et al. BCR-ABL mRNA levels at and after the time of a complete cytogenetic response (CCR) predict the duration of CCR in imatinib mesylate-treated patients with CML. Blood 2006;107:4250-6. Epub 2006 Feb 7.
-
-
-
-
13
-
-
33846228789
-
GIMEMA Working Party on Chronic Myeloid Leukemia. Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: By the GIMEMA Working Party on Chronic Myeloid Leukemia
-
Soverini S, Colarossi S, Gnani A, Rosti G, Castagnetti F, Poerio A, et al. GIMEMA Working Party on Chronic Myeloid Leukemia. Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia. Clin Cancer Res 2006;12:7374-9.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 7374-7379
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
Rosti, G.4
Castagnetti, F.5
Poerio, A.6
-
14
-
-
0001686739
-
Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia
-
Shah NP, Nicoll JM, Nagar B, Gorre ME, Paquette RL, Kuriyan J, et al. Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia. Cancer Cell 2002;2:117-25.
-
(2002)
Cancer Cell
, vol.2
, pp. 117-125
-
-
Shah, N.P.1
Nicoll, J.M.2
Nagar, B.3
Gorre, M.E.4
Paquette, R.L.5
Kuriyan, J.6
-
15
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
Kantarjian H, Giles F, Wunderle L, Bhalla K, O'Brien S, Wassmann B, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 2006;354:2542-51.
-
(2006)
N Engl J Med
, vol.354
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
Bhalla, K.4
O'Brien, S.5
Wassmann, B.6
-
16
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, Donato N, Nicoll J, Paquette R, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354:2531-41.
-
(2006)
N Engl J Med
, vol.354
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
Donato, N.4
Nicoll, J.5
Paquette, R.6
-
17
-
-
38549167019
-
Dasatinib for the treatment of Philadelphia chromosome-positive chronic myelogenous leukaemia after imatinib failure
-
Review
-
Hochhaus A. Dasatinib for the treatment of Philadelphia chromosome-positive chronic myelogenous leukaemia after imatinib failure. Expert Opin Pharmacother 2007;8:3257-64. Review.
-
(2007)
Expert Opin Pharmacother
, vol.8
, pp. 3257-3264
-
-
Hochhaus, A.1
-
18
-
-
54249151670
-
Bosutinib is safe and active in patients (pts) with chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to imatinib and other tyrosine kinase inhibitors
-
May 20 suppl; abstr 7001
-
Bruemmendorf TH, Cervantes F, Kim D, Chandy M, Fischer T, Hochhaus A, et al. Bosutinib is safe and active in patients (pts) with chronic phase (CP) chronic myeloid leukemia (CML) with resistance or intolerance to imatinib and other tyrosine kinase inhibitors. J Clin Oncol 2008:26 (May 20 suppl; abstr 7001)
-
(2008)
J Clin Oncol
, pp. 26
-
-
Bruemmendorf, T.H.1
Cervantes, F.2
Kim, D.3
Chandy, M.4
Fischer, T.5
Hochhaus, A.6
-
19
-
-
30444455167
-
-
Vitale A, Guarini A, Ariola C, Mancini M, Mecucci C, Cuneo A, et al. Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol. Blood 2006;107:473-9. Epub 2005 Sep 22.
-
Vitale A, Guarini A, Ariola C, Mancini M, Mecucci C, Cuneo A, et al. Adult T-cell acute lymphoblastic leukemia: biologic profile at presentation and correlation with response to induction treatment in patients enrolled in the GIMEMA LAL 0496 protocol. Blood 2006;107:473-9. Epub 2005 Sep 22.
-
-
-
-
22
-
-
41349083561
-
Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606
-
Konig H, Holyoake TL, Bhatia R. Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606. Blood 2008;111:2329-38.
-
(2008)
Blood
, vol.111
, pp. 2329-2338
-
-
Konig, H.1
Holyoake, T.L.2
Bhatia, R.3
-
23
-
-
42749085070
-
Tailoring tyrosine kinase inhibitor therapy to tackle specific BCR-ABL1 mutant clones
-
Epub Feb 1
-
Quintás-Cardama A, Cortes J. Tailoring tyrosine kinase inhibitor therapy to tackle specific BCR-ABL1 mutant clones. Leuk Res 2008;32:1313-6. Epub 2008 Feb 1.
-
(2008)
Leuk Res 2008
, vol.32
, pp. 1313-1316
-
-
Quintás-Cardama, A.1
Cortes, J.2
-
24
-
-
0037439689
-
SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice
-
Golas JM, Arndt K, Etienne C, Lucas J, Nardin D, Gibbons J, et al. SKI-606, a 4-anilino-3-quinolinecarbonitrile dual inhibitor of Src and Abl kinases, is a potent antiproliferative agent against chronic myelogenous leukemia cells in culture and causes regression of K562 xenografts in nude mice. Cancer Res 2003:15;63:375-81.
-
(2003)
Cancer Res
, vol.15
, Issue.63
, pp. 375-381
-
-
Golas, J.M.1
Arndt, K.2
Etienne, C.3
Lucas, J.4
Nardin, D.5
Gibbons, J.6
-
25
-
-
20144361879
-
Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles
-
Boschelli DH, Wu B, Barrios Sosa AC, Durutlic H, Chen JJ, Wang Y, et al. Synthesis and Src kinase inhibitory activity of 2-phenyl- and 2-thienyl-7-phenylaminothieno[3,2-b]pyridine-6-carbonitriles. J Med Chem 2005;48:3891-902.
-
(2005)
J Med Chem
, vol.48
, pp. 3891-3902
-
-
Boschelli, D.H.1
Wu, B.2
Barrios Sosa, A.C.3
Durutlic, H.4
Chen, J.J.5
Wang, Y.6
-
26
-
-
20444500171
-
SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models
-
Golas JM, Lucas J, Etienne C, Golas J, Discafani C, Sridharan L, et al. SKI-606, a Src/Abl inhibitor with in vivo activity in colon tumor xenograft models. Cancer Res 2005;65:5358-64.
-
(2005)
Cancer Res
, vol.65
, pp. 5358-5364
-
-
Golas, J.M.1
Lucas, J.2
Etienne, C.3
Golas, J.4
Discafani, C.5
Sridharan, L.6
-
27
-
-
24944489151
-
4-Anilino-7,8-dialkoxybenzo [g]quinoline-3-carbonitriles as potent Src kinase inhibitors
-
Berger DM, Dutia M, Birnberg G, Powell D, Boschelli DH, Wang YD, et al. 4-Anilino-7,8-dialkoxybenzo [g]quinoline-3-carbonitriles as potent Src kinase inhibitors. J Med Chem 2005;48:5909-20.
-
(2005)
J Med Chem
, vol.48
, pp. 5909-5920
-
-
Berger, D.M.1
Dutia, M.2
Birnberg, G.3
Powell, D.4
Boschelli, D.H.5
Wang, Y.D.6
-
28
-
-
33845806858
-
-
Puttini M, Coluccia AM, Boschelli F, Cleris L, Marchesi E, Donella- Deana, Aet al. In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells. Cancer Res 2006;66:11314-22. Epub 2006 Nov 17.
-
Puttini M, Coluccia AM, Boschelli F, Cleris L, Marchesi E, Donella- Deana, Aet al. In vitro and in vivo activity of SKI-606, a novel Src-Abl inhibitor, against imatinib-resistant Bcr-Abl+ neoplastic cells. Cancer Res 2006;66:11314-22. Epub 2006 Nov 17.
-
-
-
|