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Volumn 68, Issue 20, 2008, Pages 8369-8376

Early therapy evaluation of combined anti-death receptor 5 antibody and gemcitabine in orthotopic pancreatic tumor xenograftsby diffusion-weighted magnetic resonance imaging

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; GEMCITABINE; SODIUM CHLORIDE; TRA 8; UNCLASSIFIED DRUG;

EID: 54249116378     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-1771     Document Type: Article
Times cited : (44)

References (38)
  • 1
    • 8244254377 scopus 로고    scopus 로고
    • Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: A randomized trial
    • Burris HA III, Moore MJ, Andersen J, et al. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-13.
    • (1997) J Clin Oncol , vol.15 , pp. 2403-2413
    • Burris III, H.A.1    Moore, M.J.2    Andersen, J.3
  • 2
    • 0036682041 scopus 로고    scopus 로고
    • Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297
    • Berlin JD, Catalano P, Thomas JP, Kugler JW, Haller DG, Benson AB III. Phase III study of gemcitabine in combination with fluorouracil versus gemcitabine alone in patients with advanced pancreatic carcinoma: Eastern Cooperative Oncology Group Trial E2297. J Clin Oncol 2002;20:3270-5.
    • (2002) J Clin Oncol , vol.20 , pp. 3270-3275
    • Berlin, J.D.1    Catalano, P.2    Thomas, J.P.3    Kugler, J.W.4    Haller, D.G.5    Benson III, A.B.6
  • 3
    • 4644327989 scopus 로고    scopus 로고
    • Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate
    • Rocha Lima CM, Green MR, Rotche R, et al. Irinotecan plus gemcitabine results in no survival advantage compared with gemcitabine monotherapy in patients with locally advanced or metastatic pancreatic cancer despite increased tumor response rate. J Clin Oncol 2004;22:3776-83.
    • (2004) J Clin Oncol , vol.22 , pp. 3776-3783
    • Rocha Lima, C.M.1    Green, M.R.2    Rotche, R.3
  • 4
    • 23644437797 scopus 로고    scopus 로고
    • Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: A randomised phase II trial of the Italian oncology group for clinical research (GOIRC)
    • Di Costanzo F, Carlini P, Doni L, et al. Gemcitabine with or without continuous infusion 5-FU in advanced pancreatic cancer: a randomised phase II trial of the Italian oncology group for clinical research (GOIRC). Br J Cancer 2005;93:185-9.
    • (2005) Br J Cancer , vol.93 , pp. 185-189
    • Di Costanzo, F.1    Carlini, P.2    Doni, L.3
  • 5
    • 20644464360 scopus 로고    scopus 로고
    • Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: Results of a GERCOR and GISCAD phase III trial
    • Louvet C, Labianca R, Hammel P, et al. Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer: results of a GERCOR and GISCAD phase III trial. J Clin Oncol 2005;23:3509-16.
    • (2005) J Clin Oncol , vol.23 , pp. 3509-3516
    • Louvet, C.1    Labianca, R.2    Hammel, P.3
  • 6
    • 0034956807 scopus 로고    scopus 로고
    • Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death
    • Ibrahim SM, Ringel J, Schmidt C, et al. Pancreatic adenocarcinoma cell lines show variable susceptibility to TRAIL-mediated cell death. Pancreas 2001;23:72-9.
    • (2001) Pancreas , vol.23 , pp. 72-79
    • Ibrahim, S.M.1    Ringel, J.2    Schmidt, C.3
  • 7
    • 0035835494 scopus 로고    scopus 로고
    • Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer
    • Ozawa F, Friess H, Kleeff J, et al. Effects and expression of TRAIL and its apoptosis-promoting receptors in human pancreatic cancer. Cancer Lett 2001;163:71-81.
    • (2001) Cancer Lett , vol.163 , pp. 71-81
    • Ozawa, F.1    Friess, H.2    Kleeff, J.3
  • 8
    • 0030792712 scopus 로고    scopus 로고
    • Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors
    • Sheridan JP, Marsters SA, Pitti RM, et al. Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors. Science 1997;277:818-21.
    • (1997) Science , vol.277 , pp. 818-821
    • Sheridan, J.P.1    Marsters, S.A.2    Pitti, R.M.3
  • 9
    • 0032929520 scopus 로고    scopus 로고
    • Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo
    • Walczak H, Miller RE, Ariail K, et al. Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo. Nat Med 1999;5:157-63.
    • (1999) Nat Med , vol.5 , pp. 157-163
    • Walczak, H.1    Miller, R.E.2    Ariail, K.3
  • 10
    • 0032713075 scopus 로고    scopus 로고
    • Safety and antitumor activity of recombinant soluble Apo2 ligand
    • Ashkenazi A, Pai RC, Fong S, et al. Safety and antitumor activity of recombinant soluble Apo2 ligand. J Clin Invest 1999;104:155-62.
    • (1999) J Clin Invest , vol.104 , pp. 155-162
    • Ashkenazi, A.1    Pai, R.C.2    Fong, S.3
  • 11
    • 0034652156 scopus 로고    scopus 로고
    • Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy
    • Chinnaiyan AM, Prasad U, Shankar S, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci U S A 2000;97:1754-9.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 1754-1759
    • Chinnaiyan, A.M.1    Prasad, U.2    Shankar, S.3
  • 12
    • 0030996297 scopus 로고    scopus 로고
    • The receptor for the cytotoxic ligand TRAIL
    • Pan G, O'Rourke K, Chinnaiyan AM, et al. The receptor for the cytotoxic ligand TRAIL. Science 1997;276:111-3.
    • (1997) Science , vol.276 , pp. 111-113
    • Pan, G.1    O'Rourke, K.2    Chinnaiyan, A.M.3
  • 13
    • 0030880548 scopus 로고    scopus 로고
    • TRAIL-R2: A novel apoptosis-mediating receptor for TRAIL
    • Walczak H, Degli-Esposti MA, Johnson RS, et al. TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL. EMBO J 1997;16:5386-97.
    • (1997) EMBO J , vol.16 , pp. 5386-5397
    • Walczak, H.1    Degli-Esposti, M.A.2    Johnson, R.S.3
  • 14
    • 0031406386 scopus 로고    scopus 로고
    • Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway
    • Chaudhary PM, Eby M, Jasmin A, Bookwalter A, Murray J, Hood L. Death receptor 5, a new member of the TNFR family, and DR4 induce FADD-dependent apoptosis and activate the NF-κB pathway. Immunity 1997;7:821-30.
    • (1997) Immunity , vol.7 , pp. 821-830
    • Chaudhary, P.M.1    Eby, M.2    Jasmin, A.3    Bookwalter, A.4    Murray, J.5    Hood, L.6
  • 15
    • 0031405585 scopus 로고    scopus 로고
    • TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB
    • Schneider P, Thome M, Burns K, et al. TRAIL receptors 1 (DR4) and 2 (DR5) signal FADD-dependent apoptosis and activate NF-κB. Immunity 1997;7:831-6.
    • (1997) Immunity , vol.7 , pp. 831-836
    • Schneider, P.1    Thome, M.2    Burns, K.3
  • 16
    • 0034022160 scopus 로고    scopus 로고
    • Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand
    • Jo M, Kim TH, Seol DW, et al. Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand. Nat Med 2000;6:564-7.
    • (2000) Nat Med , vol.6 , pp. 564-567
    • Jo, M.1    Kim, T.H.2    Seol, D.W.3
  • 17
    • 0030762815 scopus 로고    scopus 로고
    • An antagonist decoy receptor and a death domain-containing receptor for TRAIL
    • Pan G, Ni J, Wei YF, Yu G, Gentz R, Dixit VM. An antagonist decoy receptor and a death domain-containing receptor for TRAIL. Science 1997;277:815-8.
    • (1997) Science , vol.277 , pp. 815-818
    • Pan, G.1    Ni, J.2    Wei, Y.F.3    Yu, G.4    Gentz, R.5    Dixit, V.M.6
  • 18
    • 0031414749 scopus 로고    scopus 로고
    • The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain
    • Degli-Esposti MA, Dougall WC, Smolak PJ, Waugh JY, Smith CA, Goodwin RG. The novel receptor TRAIL-R4 induces NF-κB and protects against TRAIL-mediated apoptosis, yet retains an incomplete death domain. Immunity 1997;7:813-20.
    • (1997) Immunity , vol.7 , pp. 813-820
    • Degli-Esposti, M.A.1    Dougall, W.C.2    Smolak, P.J.3    Waugh, J.Y.4    Smith, C.A.5    Goodwin, R.G.6
  • 19
    • 0030869432 scopus 로고    scopus 로고
    • Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family
    • Degli-Esposti MA, Smolak PJ, Walczak H, et al. Cloning and characterization of TRAIL-R3, a novel member of the emerging TRAIL receptor family. J Exp Med 1997;186:1165-70.
    • (1997) J Exp Med , vol.186 , pp. 1165-1170
    • Degli-Esposti, M.A.1    Smolak, P.J.2    Walczak, H.3
  • 20
    • 7344233085 scopus 로고    scopus 로고
    • Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL
    • Emery JG, McDonnell P, Burke MB, et al. Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL. J Biol Chem 1998;273:14363-7.
    • (1998) J Biol Chem , vol.273 , pp. 14363-14367
    • Emery, J.G.1    McDonnell, P.2    Burke, M.B.3
  • 21
    • 17944376030 scopus 로고    scopus 로고
    • Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity
    • Ichikawa K, Liu W, Zhao L, et al. Tumoricidal activity of a novel anti-human DR5 monoclonal antibody without hepatocyte cytotoxicity. Nat Med 2001;7:954-60.
    • (2001) Nat Med , vol.7 , pp. 954-960
    • Ichikawa, K.1    Liu, W.2    Zhao, L.3
  • 22
    • 37549019355 scopus 로고    scopus 로고
    • TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth
    • Derosier LC, Vickers SM, Zinn KR, et al. TRA-8 anti-DR5 monoclonal antibody and gemcitabine induce apoptosis and inhibit radiologically validated orthotopic pancreatic tumor growth. Mol Cancer Ther 2007;6:3198-207.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3198-3207
    • Derosier, L.C.1    Vickers, S.M.2    Zinn, K.R.3
  • 23
    • 0033580926 scopus 로고    scopus 로고
    • Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation
    • Saleh A, Srinivasula SM, Acharya S, Fishel R, Alnemri ES. Cytochrome c and dATP-mediated oligomerization of Apaf-1 is a prerequisite for procaspase-9 activation. J Biol Chem 1999;274:17941-5.
    • (1999) J Biol Chem , vol.274 , pp. 17941-17945
    • Saleh, A.1    Srinivasula, S.M.2    Acharya, S.3    Fishel, R.4    Alnemri, E.S.5
  • 24
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade
    • Li P, Nijhawan D, Budihardjo I, et al. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade. Cell 1997;91:479-89.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3
  • 25
    • 33646404891 scopus 로고    scopus 로고
    • The functional diffusion map: An imaging biomarker for the early prediction of cancer treatment outcome
    • Moffat BA, Chenevert TL, Meyer CR, et al. The functional diffusion map: an imaging biomarker for the early prediction of cancer treatment outcome. Neoplasia 2006;8:259-67.
    • (2006) Neoplasia , vol.8 , pp. 259-267
    • Moffat, B.A.1    Chenevert, T.L.2    Meyer, C.R.3
  • 26
    • 0033140111 scopus 로고    scopus 로고
    • Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging
    • Galons JP, Altbach MI, Paine-Murrieta GD, Taylor CW, Gillies RJ. Early increases in breast tumor xenograft water mobility in response to paclitaxel therapy detected by non-invasive diffusion magnetic resonance imaging. Neoplasia 1999;1:113-7.
    • (1999) Neoplasia , vol.1 , pp. 113-117
    • Galons, J.P.1    Altbach, M.I.2    Paine-Murrieta, G.D.3    Taylor, C.W.4    Gillies, R.J.5
  • 27
    • 33947654364 scopus 로고    scopus 로고
    • Predicting response of colorectal hepatic metastasis: Value of pretreatment apparent diffusion coefficients
    • Koh DM, Scurr E, Collins D, et al. Predicting response of colorectal hepatic metastasis: value of pretreatment apparent diffusion coefficients. AJR Am J Roentgenol 2007;188:1001-8.
    • (2007) AJR Am J Roentgenol , vol.188 , pp. 1001-1008
    • Koh, D.M.1    Scurr, E.2    Collins, D.3
  • 28
    • 0034694661 scopus 로고    scopus 로고
    • Diffusion magnetic resonance imaging: An early surrogate marker of therapeutic efficacy in brain tumors
    • Chenevert TL, Stegman LD, Taylor JM, et al. Diffusion magnetic resonance imaging: an early surrogate marker of therapeutic efficacy in brain tumors. J Natl Cancer Inst 2000;92:2029-36.
    • (2000) J Natl Cancer Inst , vol.92 , pp. 2029-2036
    • Chenevert, T.L.1    Stegman, L.D.2    Taylor, J.M.3
  • 29
    • 0025602549 scopus 로고
    • Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats
    • Abrams MJ, Juweid M, tenKate CI, et al. Technetium-99m-human polyclonal IgG radiolabeled via the hydrazino nicotinamide derivative for imaging focal sites of infection in rats. J Nucl Med 1990;31:2022-8.
    • (1990) J Nucl Med , vol.31 , pp. 2022-2028
    • Abrams, M.J.1    Juweid, M.2    tenKate, C.I.3
  • 30
    • 0029364632 scopus 로고
    • 99mTc]Tricine: A useful precursor complex for the radiolabeling of hydrazinonicotinate protein conjugates
    • 99mTc]Tricine: a useful precursor complex for the radiolabeling of hydrazinonicotinate protein conjugates. Bioconjug Chem 1995;6:635-8.
    • (1995) Bioconjug Chem , vol.6 , pp. 635-638
    • Larsen, S.K.1    Solomon, H.F.2    Caldwell, G.3    Abrams, M.J.4
  • 31
    • 71849104860 scopus 로고
    • Protein measurement with the folin phenol reagent
    • Lowry O, Rosebrough N, Farr L, Randall R. Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-75.
    • (1951) J Biol Chem , vol.193 , pp. 265-275
    • Lowry, O.1    Rosebrough, N.2    Farr, L.3    Randall, R.4
  • 32
    • 0347600474 scopus 로고    scopus 로고
    • Magnetic resonance elastography and diffusion-weighted imaging of the sol/gel phase transition in agarose
    • Sack I, Gedat E, Bernarding J, Buntkowsky G, Braun J. Magnetic resonance elastography and diffusion-weighted imaging of the sol/gel phase transition in agarose. J Magn Reson 2004;166:252-61.
    • (2004) J Magn Reson , vol.166 , pp. 252-261
    • Sack, I.1    Gedat, E.2    Bernarding, J.3    Buntkowsky, G.4    Braun, J.5
  • 34
    • 0020588514 scopus 로고
    • Biomedical image processing
    • Sternberg SR. Biomedical image processing. IEEE Comput 1983;16:22-34.
    • (1983) IEEE Comput , vol.16 , pp. 22-34
    • Sternberg, S.R.1
  • 36
    • 34848912648 scopus 로고    scopus 로고
    • Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer
    • s
    • Derosier LC, Buchsbaum DJ, Oliver PG, et al. Combination treatment with TRA-8 anti death receptor 5 antibody and CPT-11 induces tumor regression in an orthotopic model of pancreatic cancer. Clin Cancer Res 2007;13:5535-43s.
    • (2007) Clin Cancer Res , vol.13 , pp. 5535-5543
    • Derosier, L.C.1    Buchsbaum, D.J.2    Oliver, P.G.3
  • 37
    • 42549143998 scopus 로고    scopus 로고
    • Single-photon emission computed tomography imaging with a humanized, apoptosis-inducing antibody targeting human death receptor 5 in pancreas and breast tumor xenografts
    • Kim H, Chaudhuri TR, Buchsbaum DJ, Wang D, Zinn KR. Single-photon emission computed tomography imaging with a humanized, apoptosis-inducing antibody targeting human death receptor 5 in pancreas and breast tumor xenografts. Cancer Biol Ther 2007;6:1396-402.
    • (2007) Cancer Biol Ther , vol.6 , pp. 1396-1402
    • Kim, H.1    Chaudhuri, T.R.2    Buchsbaum, D.J.3    Wang, D.4    Zinn, K.R.5
  • 38
    • 34147136700 scopus 로고    scopus 로고
    • High-resolution single-photon emission computed tomography and X-ray computed tomography imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts
    • Kim H, Chaudhuri TR, Buchsbaum DJ, Wang D, Zinn KR. High-resolution single-photon emission computed tomography and X-ray computed tomography imaging of Tc-99m-labeled anti-DR5 antibody in breast tumor xenografts. Mol Cancer Ther 2007;6:866-75.
    • (2007) Mol Cancer Ther , vol.6 , pp. 866-875
    • Kim, H.1    Chaudhuri, T.R.2    Buchsbaum, D.J.3    Wang, D.4    Zinn, K.R.5


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