Synthesis and biological evaluation of diversely substituted indolin-2-ones

European Journal of Medicinal Chemistry

Volumn 43, Issue 11, 2008, Pages 2316-2322

  Bouchikhi, Fadoua ^a   Rossignol, Emilie ^a   Sancelme, Martine ^a   Aboab, Bettina ^a   Anizon, Fabrice ^a   Fabbro, Doriano ^b   Prudhomme, Michelle ^a   Moreau, Pascale ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

Antimicrobial agents; Indolin 2 ones; Kinases' inhibitors

Indexed keywords

2 AMINO 5 [[(2 OXOINDOLIN 3 YLIDENE)METHYL]AMINO]PENTANOIC ACID; 2 AMINO 5 [[(5 BROMO 2 OXOINDOLIN 3 YLIDENE)METHYL]AMINO]PENTANOIC ACID; 2 AMINO 6 [[(2 OXOINDOLIN 3 YLIDENE)METHYL]AMINO]HEXANOIC ACID; 5 BROMO 3 ETHOXYMETHYLENEINDOLIN 2 ONE; ABELSON KINASE; ANTIINFECTIVE AGENT; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIN DEPENDENT KINASE 2; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN RET; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; SCATTER FACTOR RECEPTOR; SOMATOMEDIN BINDING PROTEIN 1; STEROID RECEPTOR COACTIVATOR 1; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR 2;

ANTIBACTERIAL ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; BACILLUS CEREUS; CANDIDA ALBICANS; DRUG SYNTHESIS; ENZYME INHIBITION; ESCHERICHIA COLI; NONHUMAN; STREPTOMYCES;

ANTI-BACTERIAL AGENTS; BIOLOGICAL PHENOMENA; COMPUTER SIMULATION; INDOLES; ISOMERISM; MICROBIAL VIABILITY; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PROTEIN KINASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 54049157514     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.01.010     Document Type: Article

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