Impact of prolonged physical training on the pituitary glucocorticoid sensitivity determined by very low dose intravenous dexamethasone suppression test

Hormone and Metabolic Research

Volumn 40, Issue 10, 2008, Pages 718-721

  Silva, T S ^a   Longui, C A ^a,d   Faria, C D C ^a   Rocha, M N ^a   Melo, M R ^a   Faria, T G ^b   De Souza E Almeida, J A ^b   Hayashi, L F ^c   Kater, C E ^c  

^a FACULDADE DE CIÊNCIAS MÉDICAS DA SANTA CASA DE SÃO PAULO   (Brazil)

^b Brazilian Air Force   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^d NONE   (Brazil)

Author keywords

Bioelectrical impedance; Exercise; Glucocorticoid action; HPA axis; Negative feedback

Indexed keywords

DEXAMETHASONE; GLUCOCORTICOID;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG SENSITIVITY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPOPHYSIS; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; MALE; PRIORITY JOURNAL; TRAINING;

ADOLESCENT; ADULT; ANTHROPOMETRY; BODY COMPOSITION; BRAZIL; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC IMPEDANCE; EXERCISE; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; INJECTIONS, INTRAVENOUS; MALE; MILITARY PERSONNEL; PITUITARY GLAND;

EID: 54049128152     PISSN: 00185043     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1078727     Document Type: Article

References (36)

1. Hjemdahl P. Stress and the metabolic syndrome: an interesting but enigmatic association. Circulation 2002; 106: 2634-2636
2. Kyrou I, Tsigos C. Stress mechanisms and metabolic complications. Horm Metab Res 2007; 39: 430-438
3. Laugero KD. Reinterpretation of basal glucocorticoid feedback: implications to behavioral and metabolic disease. Vitam Horm 2004; 69: 1-29
4. Charmandari E, Kino T, Chrousos GP. Glucocorticoids and their actions: an introduction. Ann N Y Acad Sci 2004; 1024: 1-8
5. Singh A, Petrides JS, Gold PW, Chrousos GP, Deuster PA. Differential hypothalamic-pituitary-adrenal axis reactivity to psychological and physical stress. J Clin Endocrinol Metab 1999; 84: 1944-1948
6. Maresh CM, Whittlesey MJ, Armstrong LE, Yamamoto LM, Judelson DA, Fish KE, Casa DJ, Kavouras SA, Castracane VD. Effect of hydration state on testosterone and cortisol responses to training-intensity exercise in collegiate runners. Int J Sports Med 2006; 27: 765-770
7. Park E, Chan O, Li Q, Kiraly M, Matthews SG, Vranic M, Riddell MC. Changes in basal hypothalamo-pituitary-adrenal activity during exercise training are centrally mediated. Am J Physiol Regul Integr Comp Physiol 2005; 289: R1360-R1371
8. Pervanidou P, Chrousos GP. Post-traumatic stress disorder in children and adolescents: from Sigmund Freud's "Trauma" to psychopathology and the (dys)metabolic syndrome. Horm Metab Res 2007; 39: 413-419
9. Hackney AC. Exercise as a stressor to the human neuroendocrine system. Medicina (Kaunas) 2006; 42: 788-797
10. MacMurray RG, Hackney AC. Interactions of metabolic hormones, adipose tissue and exercise. Sports Med 2005; 35: 393-412
11. Duclos M, Gouarne C, Bonnemaison D. Acute and chronic effects of exercise on tissue sensitivity to glucocorticoids. J Appl Physiol 2003; 94: 869-875
12. Kargotich S, Keast D, Goodman C, Bhagat CI, Joske DJL, Dawson B, Morton AR. Monitoring 6 weeks of progressive endurance training with plasma glutamine. Int J Sports Med 2007; 28: 211-216
13. Faria CD, Longui CA. Molecular aspects of glucocorticoid sensitivity. Arq Bras Endocrinol Metabol 2006; 50: 983-995
14. Bamberger CM, Schulte HM, Chrousos GP. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr Rev 1996; 17: 245-261
15. Miller AH, Spencer RL, Stein M, MacEwen BS. Adrenal steroid receptor binding in spleen and thymus after stress or dexamethasone. Am J Physiol 1990; 259: E405-E412
16. Colli LM, do Amaral FC, Torres N, Castro M de. Interindividual glucocorticoid sensitivity in young healthy subjects: the role of glucocorticoid receptor α and β isoforms ratio. Horm Metab Res 2007; 39: 425-429
17. Charmandari E, Kino T. Novel causes of generalized glucocorticoid resistance. Horm Metab Res 2007; 39: 445-450
18. Longui CA, Giusti MM, Calliari LE, Katiki T, Kochi C, Monte O. Partial glucocorticoid resistance in obese children detected by very low dose dexamethasone suppression test. J Pediatr Endocrinol Metab 2003; 16: 1277-1282
19. Faria CDC, Cobra JF, Sousa e Silva T, Meto MR, Rocha MN, Hayashi LS, Faria TG, Souza e Almeda JA de, Kater CE, Longui CA. A very low dose intravenous dexamethasone suppression test as an index of glucocorticoid sensitivity. Horm Res 2008; 69: 357-362
20. Nieman DC, Henson DA, Davis JM, Dumke CL, Utter AC, Murphy EA, Pearce S, Gojanovich G, MacAnulty SR, MacAnulty LS. Blood leukocyte mRNA expression for IL-10, IL-1Ra, and IL-8, but not IL-6, increases after exercise. J Interferon Cytokine Res 2006; 26: 668-674
21. Petersen AM, Pedersen BK. The role of IL-6 in mediating the anti-inflammatory effects of exercise. J Physiol Pharmacol 2006; 57 (Suppl 10): 43-51
22. Starkie RL, Hargreaves M, Rolland J, Febbraio MA. Heat stress, cytokines, and the immune response to exercise. Brain Behav Immun 2005; 19: 404-412
23. Arnsworth BE, Haskell WL, Leon AS et al. Based on the compendium of physical activities. Med Sci Sport Exerc 1993; 25: 71-80
24. Petrides JS, Mueller GP, Kalogeras KT, Chrousos GP, Gold PW, Deuster PA. Exercise-induced activation of the hypothalamic-pituitary-adrenal axis: marked differences in the sensitivity to glucocorticoid suppression. J Clin Endocrinol Metab 1994; 79: 377-383
25. DeRijk RH, Petrides J, Deuster P, Gold PW, Sternberg EM. Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans. J Clin Endocrinol Metab 1996; 81: 228-235
26. Jürimäe J, Purge P, Jürimäe T. Effect of prolonged training period on plasma adiponectin in elite male rowers. Horm Metab Res 2007; 39: 519-523
27. Duclos M, Minkhar M, Sarrieau A, Bonnemaison D, Manier G, Mormede P. Reversibility of endurance training-induced changes on glucocorticoid sensitivity of monocytes by an acute exercise. Clin Endocrinol (Oxf) 1999; 51: 749-756
28. Wajchenberg BL. Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome. Endocr Rev 2000; 21: 697-738
29. Laclaustra M, Corella D, Ordovas JM. Metabolic syndrome pathophysiology: the role of adipose tissue. Nutr Metab Cardiovasc Dis 2007; 17: 125-139
30. Meerarani P, Badimon JJ, Zias E, Fuster V, Moreno PR. Metabolic syndrome and diabetic atherothrombosis: implications in vascular complications. Curr Mol Med 2006; 6: 501-514
31. Pasquali R, Vicennati V, Cacciari M, Pagotto U. The hypothalamic-pituitary-adrenal axis activity in obesity and the metabolic syndrome. Ann N Y Acad Sci 2006; 1083: 111-128
32. Duclos M, Marquez PP, Barat P, Gatta B, Roger P. Increased cortisol bioavailability, abdominal obesity, and the metabolic syndrome in obese women. Obes Res 2005; 13: 1157-1166
33. Whorwood CB, Donovan SJ, Flanagan D, Phillips DI, Byrne CD. Increased glucocorticoid receptor expression in human skeletal muscle cells may contribute to the pathogenesis of the metabolic syndrome. Diabetes 2002; 51: 1066-1075
34. Rebuffe-Scrive M, Walsh UA, MacEwen B, Rodin J. Effect of chronic stress and exogenous glucocorticoids on regional fat distribution and metabolism. Physiol Behav 1992; 52: 583-590
35. Ebrecht M, Buske-Kirschbaum A, Hellhammer D, Kern S, Rohleder N, Walker B, Kirschbaum C. Tissue specificity of glucocorticoid sensitivity in healthy adults. J Clin Endocrinol Metab 2000; 85: 3733-3739
36. Lamounier-Zepter V, Ehrhart-Bornstein M, Bornstein SR. Metabolic syndrome and the endocrine stress system. Horm Metab Res 2006; 38: 437-441