Changes in corticosteroid sensitivity of peripheral blood lymphocytes after strenuous exercise in humans

Journal of Clinical Endocrinology and Metabolism

Volumn 81, Issue 1, 1996, Pages 228-235

  Derijk, R H ^a   Petrides, J ^b   Deuster, P ^b   Gold, P W ^a   Sternberg, E M ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CORTICOSTEROID; CORTICOTROPIN; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; HYDROCORTISONE; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MIFEPRISTONE;

ADULT; ARTICLE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; EXERCISE; HORMONE SENSITIVITY; HUMAN; HUMAN EXPERIMENT; HYDROCORTISONE BLOOD LEVEL; IMMUNOMODULATION; MALE; NORMAL HUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

ADRENOCORTICOTROPIC HORMONE; ADULT; DEXAMETHASONE; DOSE-RESPONSE RELATIONSHIP, DRUG; EXERCISE; HUMANS; HYDROCORTISONE; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; LYMPHOCYTES; MALE; MIFEPRISTONE;

EID: 0030027253     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.81.1.228     Document Type: Article

References (34)

1. Chrousos GP, Gold PW. 1992 The concepts of stress and stress system disorders: overview of physical and behavioral homeostasis. JAMA. 267:1244-1252.
2. Haynes JRC, Muraad F. 1985 Adrenocorticotropin hormone: adrenocortical steroids and their synthetic analogs; inhibitors of adrenocortical steroid biosynthesis. In: Gilman AG, ed. Goodman and Gillman's the pharmacological basis of therapeutics. New York, Toronto: MacMillan: 1459-1489.
3. Barber AE, Coyle SM, Marano MA, et al. 1943 Glucocorticoid therapy alters hormonal and cytokine responses to endotoxin in man. J Immunol. 150:1999-2006.
4. Dentener MA, Brazil V, Von Asmuth EJU, Ceska M, Buurman WA. 1993 Involvement of CD14 in lipopolysaccharide-induced tumor necrosis factor-a, IL-6 and IL-8 release by human monocytes and alveolar macrophages. J Immunol. 150:2885-2891.
5. Heinrich PC, Castell JV, Andus T. 1990 Interleukin-6 and the acute phase response. Biochem J. 265:621-636.
6. Barrera P, Boermans AMTh, Janssen EM, et al. 1993 Circulating soluble tumor necrosis factor receptors, interleukin-2 receptors, tumor necrosis factor a, and interleukin-6 levels in rheumatoid arthritis. Arthritis Rheum. 36:1070-1079.
7. Damas P, Ledoux D, Nys M, et al. 1992 Cytokine serum level during severe sepsis in human IL-6 as a marker of severity. Ann Surg. 215:356-362.
8. Linden M, Brattsand R. 1994 Effects of a corticosteroids, budesonide, on alveolar macrophage and blood monocyte secretion of cytokines: differential sensitivity of GM-CSF, IL-1b and IL-6. Pul Pharmacol. 7:43-47.
9. Uehara A, Kohda H, Sekiya C, Takasugi Y, Namika M. 1989 Inhibition of interleukin-1 beta release from cultured human peripheral blood mononuclear cells by prednisolone. Experienta, 45:166-167.
10. Finch-Arietta MB, Cochran FR. 1991 Cytokine production in whole blood ex vivo. Agents Actions. 34:49-52.
11. Luger A, Deuster PA, Kyle SB, et al. 1987 Acute hypothalamic-pituitary-adrenal responses to the stress of treadmill exercise. N Engl J Med. 316:1309-1315.
12. Carbon KI, Marker JC, Arnall DA, et al. 1985 Epinephrine is unessential for stimulation of liver glycogenolysis during exercise. J Appl Physiol. 58:544-548.
13. Maccari S, Mormede P, Piazza PV, Simon H, Angelucci L, Le Moal M. 1992 Hippocampal type I and type II corticosteroid receptors are modulated by central noradrenergic systems. Psychoneuroendocrinology. 17:103-112.
14. Rosewicz S, McDonald AR, Maddux BA, Goldfine ID, Miesfeld RL, Logsdon CD. 1988 Mechanism of glucocorticoid receptor down-regulation by glucocorticoids. J Biol Chem. 263:2581-2584.
15. Paciotti G, Barron D, Licinio J, Tamarkin L. 1992 Novel immunoassays for the detection of cytokines interleukin-1alpha and interleukin-2 in the circulation of normal subjects. Prog Neuroendocrinimunol. 5:21-30,
16. Kyle SB, Smoak BL, Douglass LW, Deuster PA. 1989 Variability of responses across training levels to maximal treadmill exercise. J Appl Physiol. 67:160-165.
17. Nerad JL, Griffiths JK, Van der Meer JWM, et al. 1992 Interleukin-1 beta (IL-1beta), IL-1 receptor antagonist, and TNF alpha production in whole blood. J Leukoc Biol. 52:687-692.
18. Jones TH, Daniels M, James RA, et al. 1994 Production of bioactive and immunoreactive interleukin-6 (IL-6) and expression of IL-6 messenger ribonucleic acid by human pituitary adenomas. J Clin Endocrinol Metab. 78:180-187.
19. de Kloet ER. 1991 Brain corticosteroid receptor balance and homeostatic control. Front Neuroendocrinol. 12:95-164.
20. Armanini D, Strasser T, Weber PC. 1985 Characterization of aldosterone binding sites in circulating human mononuclear lymphocytes. Am J Physiol. 248:E388-E390.
21. Deuster PA, Curiale AM, Cowan ML, Finkelman FD. 1988 Exercise-induced changes in populations of peripheral blood mononuclear cells. Med Sci Sports Exerc. 20:276-280.
22. Deuster PA, Chrousos GP, Luger A, et al. 1989 Hormonal and metabolic responses of untrained, moderately trained and highly trained men to three exercise intensities. Metabolism. 38:141-148.
23. Schobitz B, Sutanto W, Carey MP, Holsboer F, de Kloet ER. 1994 Endotoxin and interleukin-1 decrease the affinity of hippocampal mineralocorticoid (type I) receptor in parallel to activation of the hypothalamic-pituitary-adrenal axis. Neuroendocrinology. 60:124-133.
24. Kam JC, Szefler SJ, Surs W, Sher W, Leung DYM. 1993 Combination IL-2 and IL-4 reduces glucocorticoid receptor-binding affinity and T cell response to glucocorticoids. J Immunol. 151:3460-3466.
25. Sprenger H, Jacobs C, Nain M, et al. 1992 Enhanced release of cytokines, interleukin-2 receptors, and neopterin after long-distance running. Clin Immunol Immunopathol. 63:108-195.
26. Dhabhar FS, Miller AH, Stein M, McEwen BS, Spencer RL. 1994 Diurnal and acute stress-induced changes in distribution of peripheral blood leukocyte subpopulation. Brain Behav Immunol. 8:66-79.
27. Manfredini R, Salmi R, Gallerani M, et al. 1994 Haematological profile in cancer patients: analysis of circadian pattern. J Intern Med Res. 22:343-349.
28. Dhabhar FS, Miller AH, McEwen BS, Spencer RL. 1995 Effects of stress on immune cell distribution. Dynamics and hormonal mechanisms. J Immunol. 154:5511-5527.
29. Tanaka H, Akama H, Ichikawa Y, Makino I, Homina M. 1992 Glucocorticoid receptor in patients with lupus nephritis: relationship between receptor levels in mononuclear leukocytes and effect of glucocorticoid therapy. J Rhematol. 19:878-883.
30. Stratakis C, Karl M, Schulte HM, Chrousos GP. 1994 Glucocorticoid resistance in humans. Ann NY Acad Sci. 746:362-373.
31. Norbiato G, Bevilacqua M, Vago T, et al. 1992 Cortisol resistance in acquired immunodeficiency syndrome. J Clin Endocrinol Metab. 74:608-613.
32. DeRijk RH, Sternberg EM. 1994 Corticosteroid action and neuroendocrine-immune interactions. Ann NY Acad Sci. 746:33-41
33. Smith CC, Omeljaniuk RJ, Whitfield HJ, et al. 1954 Differential mineralocorticoid (type 1) and glucocorticoid (type II) receptor expression in Lewis and Fisher rats. Neuroimmunomodulation. 1:66-73.
34. Eldridge JC, Fleenor DG, Kerr DS, Landfield PW. 1989 Impaired upregulation of type II corticosteroid receptors in hippocampus or aged rats. Brain Res. 478:248-256.