Adenylic dinucleotides produced by CD38 are negative endogenous modulators of platelet aggregation

Journal of Biological Chemistry

Volumn 283, Issue 36, 2008, Pages 24460-24468

  Magnone, Mirko ^a   Basile, Giovanna ^a   Bruzzese, Debora ^a   Guida, Lucrezia ^a,b   Signorello, Maria Grazia ^a   Chothi, Madhu Parakkottil ^a   Bruzzone, Santina ^a,b   Millo, Enrico ^a   Qi, Ai Dong ^c   Nicholas, Robert A ^c   Kassack, Matthias U ^d   Leoncini, Giuliana ^a   Zocchi, Elena ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b ADVANCED BIOTECHNOLOGY CENTER   (Italy)

^c UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^d HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; BLOOD SUBSTITUTES; BODY FLUIDS; CALCIUM; CALCIUM ALLOYS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; FETAL MONITORING; ISOMERS; LIQUID CHROMATOGRAPHY; MAMMALS; NITRIC OXIDE; PLATELETS;

CYCLASE; DINUCLEOTIDES; DIPHOSPHATE; INTRACELLULAR CALCIUM CONCENTRATIONS; INTRACELLULAR CALCIUMS; MAMMALIAN CELLS; PHYSIOLOGICAL AGONISTS; PLATELET ACTIVATIONS; PLATELET AGGREGATIONS; PURINERGIC RECEPTORS; RETENTION TIMES; SYNTHESIS OF;

HIGH PRESSURE LIQUID CHROMATOGRAPHY;

ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE; CALCIUM; CD38 ANTIGEN; COLLAGEN; CYCLIC AMP; DIADENOSINE 5',5''' P1,P2 DIPHOSPHATE; DINUCLEOTIDE; INOSITOL 1,4,5 TRISPHOSPHATE; NITRIC OXIDE; PURINERGIC P2Y1 RECEPTOR; PURINERGIC P2Y11 RECEPTOR; PURINERGIC P2Y12 RECEPTOR; THROMBIN; UNCLASSIFIED DRUG; ANTITHROMBOCYTIC AGENT; CD38 PROTEIN, HUMAN; DIADENOSINE PYROPHOSPHATE; DINUCLEOSIDE PHOSPHATE; HEMOSTATIC AGENT; MEMBRANE PROTEIN;

ARTICLE; CALCIUM CELL LEVEL; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; ISOMER; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTOPOIESIS; ANIMAL; CALCIUM SIGNALING; CELL PROLIFERATION; CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; GENETICS; HELA CELL; METABOLISM; MUSCLE CELL; SECRETORY VESICLE; STEREOISOMERISM; THROMBOCYTE;

MAMMALIA;

ADENOSINE DIPHOSPHATE; ANIMALS; ANTIGENS, CD38; BLOOD PLATELETS; CALCIUM; CALCIUM SIGNALING; CELL PROLIFERATION; COLLAGEN; DINUCLEOSIDE PHOSPHATES; DOSE-RESPONSE RELATIONSHIP, DRUG; HELA CELLS; HEMOSTATICS; HUMANS; MEMBRANE GLYCOPROTEINS; MUSCLE CELLS; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; SECRETORY VESICLES; STEREOISOMERISM; THROMBIN;

EID: 54049114726     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710568200     Document Type: Article

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