SAR study of a novel triene-ansamycin group compound, quinotrierixin, and related compounds, as inhibitors of ER stress-induced XBP1 activation II. Structure elucidation

Journal of Antibiotics

Volumn 61, Issue 5, 2008, Pages 312-317

  Kawamura, Tatsuro ^a   Tashiro, Etsu ^a   Shindo, Kazutoshi ^b   Imoto, Masaya ^a  

^a KEIO UNIVERSITY   (Japan)

^b JAPAN WOMEN'S UNIVERSITY   (Japan)

Author keywords

ER stress; Triene ansamycin; XBP1

Indexed keywords

ANSAMYCIN DERIVATIVE; MACROCYCLIC LACTAM; NORTRIENOMYCIN A; NORTRIENOMYCIN B; NORTRIENOMYCINOL; QUINOTRIERIXIN; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ANTIINFECTIVE AGENT; DNA BINDING PROTEIN; DRUG DERIVATIVE; RIFABUTIN; TRANSCRIPTION FACTOR; TRE BINDING PROTEIN; TRE-BINDING PROTEIN;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRESS; DRUG ISOLATION; ENDOPLASMIC RETICULUM; INFRARED SPECTROSCOPY; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; STREPTOMYCES; STRUCTURE ACTIVITY RELATION; ULTRAVIOLET SPECTROSCOPY; CHEMISTRY; CONFORMATION; HUMAN; INFRARED SPECTROPHOTOMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OPTICAL ROTATION; PHYSICAL CHEMISTRY; STRESS; ULTRAVIOLET SPECTROPHOTOMETRY;

STREPTOMYCES SP.;

ANTI-BACTERIAL AGENTS; CHEMISTRY, PHYSICAL; DNA-BINDING PROTEINS; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR CONFORMATION; OPTICAL ROTATION; RIFABUTIN; SPECTROPHOTOMETRY, INFRARED; SPECTROPHOTOMETRY, ULTRAVIOLET; STREPTOMYCES; STRESS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS;

EID: 54049108108     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.1038/ja.2008.44     Document Type: Article

References (9)

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