TMC-135A and B, new triene-ansamycins, produced by Streptomyces sp

Journal of Antibiotics

Volumn 53, Issue 7, 2000, Pages 724-727

  Nishio, M ^a   Kohno, J ^a   Sakurai, M ^a   Suzuki, S I ^a   Okada, N ^a   Kawano, K ^a   Komatsubara, S ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANSAMYCIN DERIVATIVE; ANTIBIOTIC AGENT; TMC 135A; TMC 135B; UNCLASSIFIED DRUG;

CARBON NUCLEAR MAGNETIC RESONANCE; DRUG ACTIVITY; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SCREENING; DRUG STRUCTURE; HUMAN; HUMAN CELL; IC 50; MYCELIUM; NONHUMAN; NOTE; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SPECTROSCOPY; STREPTOMYCES; TAXONOMY; TUMOR CELL LINE;

STREPTOMYCES;

EID: 0033855677     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.53.724     Document Type: Note

References (6)

1. Thiazinotrienomycins, new ansamycin group antibiotics
2. Novel trieneansamycins, cytotrienins A and B, inducing apoptosis on human leukemia HL-60 cells
3. Cytotrienin A, a novel apoptosis inducer in human leukemia HL-60 cells
4. TMC-1 A, B, C and D, new antibiotics of the manumycin group produced by Streptomyces sp. Taxonomy, production, isolation, physico-chemical properties, structure elucidation and biological properties
5. Caspase-mediated activation of a 36-kDa myelin basic protein kinase during anticancer drug-induced apoptosis
6. Effect of thiazinotrienomycin B, an ansamycin antibiotic, on the function of epidermal growth factor receptor in human stomach tumor cells