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Volumn 57, Issue 11, 2008, Pages 1583-1591

Effectiveness of antiplatelet drugs against experimental non-alcoholic fatty liver disease

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CILOSTAZOL; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE B; RAF PROTEIN; TICLOPIDINE;

EID: 54049103536     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2007.144550     Document Type: Article
Times cited : (97)

References (36)
  • 1
    • 0026640577 scopus 로고
    • Fatty infiltration of the liver: Analysis of prevalence, radiological and clinical findings
    • el-Hassan AY, Ibrahim EM, Chammas MY, et al. Fatty infiltration of the liver: analysis of prevalence, radiological and clinical findings. Br J Radiol 1992;65:774-8.
    • (1992) Br J Radiol , vol.65 , pp. 774-778
    • el-Hassan, A.Y.1    Ibrahim, E.M.2    Chammas, M.Y.3
  • 2
    • 0037299949 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis: What is it, and why is it important in the Asia-Pacific region?
    • Farrell GC. Non-alcoholic steatohepatitis: what is it, and why is it important in the Asia-Pacific region? J Gastroenterol Hepatol 2003;18:124-38.
    • (2003) J Gastroenterol Hepatol , vol.18 , pp. 124-138
    • Farrell, G.C.1
  • 3
    • 0037129380 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease
    • Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002;346:1221-31.
    • (2002) N Engl J Med , vol.346 , pp. 1221-1231
    • Angulo, P.1
  • 4
    • 0032171686 scopus 로고    scopus 로고
    • Non-alcoholic steatohepatitis (NASH): A disease of emerging identity and importance
    • James FW, Day CP. Non-alcoholic steatohepatitis (NASH): a disease of emerging identity and importance. J Hepatol 1998;29:495-501.
    • (1998) J Hepatol , vol.29 , pp. 495-501
    • James, F.W.1    Day, C.P.2
  • 6
    • 34547101692 scopus 로고    scopus 로고
    • The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats
    • Deng XQ, Chen LL, Li NX. The expression of SIRT1 in nonalcoholic fatty liver disease induced by high-fat diet in rats. Liver Int 2007;27:708-15.
    • (2007) Liver Int , vol.27 , pp. 708-715
    • Deng, X.Q.1    Chen, L.L.2    Li, N.X.3
  • 7
    • 0842308111 scopus 로고    scopus 로고
    • Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet
    • Kawaguchi K, Sakaida I, Tsuchiya M, et al. Pioglitazone prevents hepatic steatosis, fibrosis, and enzyme-altered lesions in rat liver cirrhosis induced by a choline-deficient L-amino acid-defined diet. Biochem Biophys Res Commun 2004:27;315:187-95.
    • (2004) Biochem Biophys Res Commun , vol.27 , Issue.315 , pp. 187-195
    • Kawaguchi, K.1    Sakaida, I.2    Tsuchiya, M.3
  • 8
    • 0032943606 scopus 로고    scopus 로고
    • The effects of antiplatelet agents in the prevention of ventricular tachyarrhythmias during acute myocardial ischemia in rats
    • Ahn YK, Cho JG, Kang JC, et al. The effects of antiplatelet agents in the prevention of ventricular tachyarrhythmias during acute myocardial ischemia in rats. Jpn Heart J 1999;40:79-86.
    • (1999) Jpn Heart J , vol.40 , pp. 79-86
    • Ahn, Y.K.1    Cho, J.G.2    Kang, J.C.3
  • 9
    • 0021072144 scopus 로고
    • Hemorheological effect of ticlopidine in the rat
    • Ono S, Ashida S, Abiko Y. Hemorheological effect of ticlopidine in the rat. Thrombosis Res 1983;31:549-56.
    • (1983) Thrombosis Res , vol.31 , pp. 549-556
    • Ono, S.1    Ashida, S.2    Abiko, Y.3
  • 10
    • 0034883805 scopus 로고    scopus 로고
    • Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model
    • Aoki M, Morishita R, Ogihara T, et al. Inhibition of neointimal formation after balloon injury by cilostazol, accompanied by improvement of endothelial dysfunction and induction of hepatocyte growth factor in rat diabetes model. Diabetologia 2001;44:1034-42.
    • (2001) Diabetologia , vol.44 , pp. 1034-1042
    • Aoki, M.1    Morishita, R.2    Ogihara, T.3
  • 11
    • 7044241291 scopus 로고    scopus 로고
    • Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: Role of short-form leptin receptors and osteopontin
    • Sahai A, Malladi P, Pan X, et al. Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin. Am J Physiol Gastrointest Liver Physiol 2004;287:1035-43.
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.287 , pp. 1035-1043
    • Sahai, A.1    Malladi, P.2    Pan, X.3
  • 12
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of histological scoring system for nonalcoholic fatty liver disease
    • Kleiner DE, Brunt EM, Sanyal AJ, et al. Design and validation of histological scoring system for nonalcoholic fatty liver disease. Hepatology 2005;41:1313-21.
    • (2005) Hepatology , vol.41 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Sanyal, A.J.3
  • 13
    • 0032695030 scopus 로고    scopus 로고
    • Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
    • Angulo P, Keach JC, Batts KP, et al. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-62.
    • (1999) Hepatology , vol.30 , pp. 1356-1362
    • Angulo, P.1    Keach, J.C.2    Batts, K.P.3
  • 14
    • 26044476621 scopus 로고    scopus 로고
    • High glucose stimulates hepatic stellate cells to proliferate and to produce collagen through free radical production and activation of mitogen-activated protein kinase
    • Sugimoto R, Enjoji M, Kohjima M, et al. High glucose stimulates hepatic stellate cells to proliferate and to produce collagen through free radical production and activation of mitogen-activated protein kinase. Liver Int 2005;25:1018-26.
    • (2005) Liver Int , vol.25 , pp. 1018-1026
    • Sugimoto, R.1    Enjoji, M.2    Kohjima, M.3
  • 15
    • 0032253485 scopus 로고    scopus 로고
    • Simple assay for the level of total lipid peroxides in serum or plasma
    • Yagi K. Simple assay for the level of total lipid peroxides in serum or plasma. Methods Mol Biol 1998;108:101-6.
    • (1998) Methods Mol Biol , vol.108 , pp. 101-106
    • Yagi, K.1
  • 16
    • 54349123947 scopus 로고    scopus 로고
    • Applied Biosystems. User Bulletin 2 - ABI PRISM 7700 Sequence Detection System. Applied Biosystems, Foster City, California, USA; December 11, 1997 (updated Oct 2001).
    • Applied Biosystems. User Bulletin 2 - ABI PRISM 7700 Sequence Detection System. Applied Biosystems, Foster City, California, USA; December 11, 1997 (updated Oct 2001).
  • 17
    • 0034655375 scopus 로고    scopus 로고
    • Tumor necrosis factor polymorphisms and acute rejection: Proven link or provisional association?
    • Marshall SE, Welsh KI. Tumor necrosis factor polymorphisms and acute rejection: proven link or provisional association? Transplantation 2000;69:1237-9.
    • (2000) Transplantation , vol.69 , pp. 1237-1239
    • Marshall, S.E.1    Welsh, K.I.2
  • 18
    • 0036901705 scopus 로고    scopus 로고
    • Quantitative gene expression of TGF-β1, TNF-α, IL-1β and IL-6 in the renal artery wall of chronically rejected human renal allografts
    • Zegarska J, Paczek L, Mroz A, et al. Quantitative gene expression of TGF-β1, TNF-α, IL-1β and IL-6 in the renal artery wall of chronically rejected human renal allografts. Transplant Proc 2002;34:3176-9.
    • (2002) Transplant Proc , vol.34 , pp. 3176-3179
    • Zegarska, J.1    Paczek, L.2    Mroz, A.3
  • 19
    • 27544469776 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice
    • Li J, Grigoryev DN, Polotsky VY, et al. Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice. J Appl Physiol 2005;99:1643-8.
    • (2005) J Appl Physiol , vol.99 , pp. 1643-1648
    • Li, J.1    Grigoryev, D.N.2    Polotsky, V.Y.3
  • 20
    • 34247359442 scopus 로고    scopus 로고
    • Chronic intermittent hypoxia predisposes to liver injury
    • Savransky V, Vivero A, Polotsky VY, et al. Chronic intermittent hypoxia predisposes to liver injury. Hepatology 2007;45:1007-13.
    • (2007) Hepatology , vol.45 , pp. 1007-1013
    • Savransky, V.1    Vivero, A.2    Polotsky, V.Y.3
  • 21
    • 0000961362 scopus 로고    scopus 로고
    • Ticlopidine inhibits activation of mitogen-activated protein kinase by platelet-derived growth factor in cultured rat renal cells
    • Nomiyama M, Ohnishi N, Yokoyama T, et al. Ticlopidine inhibits activation of mitogen-activated protein kinase by platelet-derived growth factor in cultured rat renal cells. Clin Exp Nephrol 1998;2:117-23.
    • (1998) Clin Exp Nephrol , vol.2 , pp. 117-123
    • Nomiyama, M.1    Ohnishi, N.2    Yokoyama, T.3
  • 22
    • 0028936254 scopus 로고
    • Platelet-derived growth factor and angiotensin 2 stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: Comparison of hypertrophic and hyperplastic agonists
    • Huwiler A, Stabel S, Pfeilschifter J, et al. Platelet-derived growth factor and angiotensin 2 stimulate the mitogen-activated protein kinase cascade in renal mesangial cells: comparison of hypertrophic and hyperplastic agonists. Biochem J 1995;305:777-84.
    • (1995) Biochem J , vol.305 , pp. 777-784
    • Huwiler, A.1    Stabel, S.2    Pfeilschifter, J.3
  • 23
    • 33748205007 scopus 로고    scopus 로고
    • Therapy of NAFLD: Antioxidants and cytoprotective agents
    • Chang CY, Argo CK, Caldwell SH, et al. Therapy of NAFLD: antioxidants and cytoprotective agents. J Clin Gastroenterol 2006;40:51-60.
    • (2006) J Clin Gastroenterol , vol.40 , pp. 51-60
    • Chang, C.Y.1    Argo, C.K.2    Caldwell, S.H.3
  • 24
    • 33644900462 scopus 로고    scopus 로고
    • Review article: Drug therapy for non-alcoholic fatty liver disease
    • Comar KM, Sterling RK. Review article: drug therapy for non-alcoholic fatty liver disease. Aliment Pharmacol Ther 2006;23:207-15.
    • (2006) Aliment Pharmacol Ther , vol.23 , pp. 207-215
    • Comar, K.M.1    Sterling, R.K.2
  • 25
    • 0012785395 scopus 로고    scopus 로고
    • Metformin reverses fatty liver disease in obese, leptin-daficient mice
    • Lin HZ, Yang SQ, Diehl AM, et al. Metformin reverses fatty liver disease in obese, leptin-daficient mice. Nat Med 2000;6:998-1003.
    • (2000) Nat Med , vol.6 , pp. 998-1003
    • Lin, H.Z.1    Yang, S.Q.2    Diehl, A.M.3
  • 26
    • 1242340416 scopus 로고    scopus 로고
    • Acarbose attenuates experimental non-alcoholic steatohepatitis
    • Lieber CS, Leo MA, DeCarli LM, et al. Acarbose attenuates experimental non-alcoholic steatohepatitis. Biochem Biophys Res Commun 2004;12:699-703.
    • (2004) Biochem Biophys Res Commun , vol.12 , pp. 699-703
    • Lieber, C.S.1    Leo, M.A.2    DeCarli, L.M.3
  • 27
    • 33645891166 scopus 로고    scopus 로고
    • Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR delta agonist, on development of steatohepatitis in mice fed a methionine-and choline-deficient diet
    • Nagasawa T, Inada Y, Shibata N, et al. Effects of bezafibrate, PPAR pan-agonist, and GW501516, PPAR delta agonist, on development of steatohepatitis in mice fed a methionine-and choline-deficient diet. Eur J Pharmacol 2006;536:182-91.
    • (2006) Eur J Pharmacol , vol.536 , pp. 182-191
    • Nagasawa, T.1    Inada, Y.2    Shibata, N.3
  • 28
    • 0029829651 scopus 로고    scopus 로고
    • Hepatic sinusoidal fibrosis induced by cholesterol and stilbestrol in the rabbit: 1. Morphology and inhibition of fibrogenesis by dipyridamole
    • Wanless IR, Belgiomo J, Huet PM. Hepatic sinusoidal fibrosis induced by cholesterol and stilbestrol in the rabbit: 1. Morphology and inhibition of fibrogenesis by dipyridamole. Hepatology 1996;24:855-64.
    • (1996) Hepatology , vol.24 , pp. 855-864
    • Wanless, I.R.1    Belgiomo, J.2    Huet, P.M.3
  • 29
    • 0031974158 scopus 로고    scopus 로고
    • Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin
    • Murohara T, Horowitz JR, Isner JM, et al. Vascular endothelial growth factor/vascular permeability factor enhances vascular permeability via nitric oxide and prostacyclin. Circulation 1998;97:99-107.
    • (1998) Circulation , vol.97 , pp. 99-107
    • Murohara, T.1    Horowitz, J.R.2    Isner, J.M.3
  • 30
    • 0032993694 scopus 로고    scopus 로고
    • Aspirin inhibits inducible nitric oxide synthase expression and tumor necrosis factor-alpha release by cultured smooth muscle cells
    • Sánchez de Miguel L, de Frutos T, López-Farré A, et al. Aspirin inhibits inducible nitric oxide synthase expression and tumor necrosis factor-alpha release by cultured smooth muscle cells. Eur J Clin Invest 1999;29:93-9.
    • (1999) Eur J Clin Invest , vol.29 , pp. 93-99
    • Sánchez de Miguel, L.1    de Frutos, T.2    López-Farré, A.3
  • 31
    • 20044385758 scopus 로고    scopus 로고
    • Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma
    • Campbell JS, Hughes SD, Fausto N, et al. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc Natl Acad Sci USA 2005;102:3389-94.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 3389-3394
    • Campbell, J.S.1    Hughes, S.D.2    Fausto, N.3
  • 32
    • 20444376949 scopus 로고    scopus 로고
    • Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals
    • Prattali RR, Barreiro GC, Carvalheira JB, et al. Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals. FEBS Lett 2005;579:3152-8.
    • (2005) FEBS Lett , vol.579 , pp. 3152-3158
    • Prattali, R.R.1    Barreiro, G.C.2    Carvalheira, J.B.3
  • 33
    • 0029161583 scopus 로고
    • Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-3 and type-4 suppress mitogenesis of rat mesangial cells
    • Matousovic K, Grande JP, Dousa TP, et al. Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-3 and type-4 suppress mitogenesis of rat mesangial cells. J Clin Invest 1995;96:401-10.
    • (1995) J Clin Invest , vol.96 , pp. 401-410
    • Matousovic, K.1    Grande, J.P.2    Dousa, T.P.3
  • 34
    • 2342595896 scopus 로고    scopus 로고
    • The CREB family: Key regulators of hepatic metabolism
    • Montminy M, Koo SH, Zhang X, et al. The CREB family: key regulators of hepatic metabolism. Ann Endocrinol 2004;65:73-5.
    • (2004) Ann Endocrinol , vol.65 , pp. 73-75
    • Montminy, M.1    Koo, S.H.2    Zhang, X.3
  • 35
    • 0031965333 scopus 로고    scopus 로고
    • Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines
    • Klemm DJ, Roesler WJ, Reusch JE, et al. Insulin stimulates cAMP-response element binding protein activity in HepG2 and 3T3-L1 cell lines. J Biol Chem 1998;273:917-23.
    • (1998) J Biol Chem , vol.273 , pp. 917-923
    • Klemm, D.J.1    Roesler, W.J.2    Reusch, J.E.3
  • 36
    • 17544374598 scopus 로고    scopus 로고
    • Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors
    • Woo CW, Siow YL, O K, et al. Hyperhomocysteinemia induces hepatic cholesterol biosynthesis and lipid accumulation via activation of transcription factors. Am J Physiol Endocrinol Metab 2005;288: 1002-10.
    • (2005) Am J Physiol Endocrinol Metab , vol.288 , pp. 1002-1010
    • Woo, C.W.1    Siow2    YL, O.K.3


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