Characterisation of a pre-cell hit detector to be used in single cell irradiation experiments at the Lund Nuclear Microprobe

Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms

Volumn 266, Issue 21, 2008, Pages 4808-4815

  Nilsson, Charlotta ^a   Pallon, Jan ^a   Thungström, Göran ^b   Marrero, Natalia Arteaga ^a   Elfman, Mikael ^a   Kristiansson, Per ^a   Nilsson, Christer ^a   Wegdén, Marie ^a  

^a LUND UNIVERSITY   (Sweden)

^b MID SWEDEN UNIVERSITY   (Sweden)

Author keywords

E detector; Detector efficiency; Single ions; Thin silicon detector; Vacuum window

Indexed keywords

CELLS; CYTOLOGY; ELECTROLYSIS; ION BEAM LITHOGRAPHY; IONS; SEMICONDUCTING SILICON; SEMICONDUCTING SILICON COMPOUNDS; SILICON; SILICON WAFERS; VACUUM; VACUUM TECHNOLOGY; WINDOWS;

BEAM SIZES; BEAM SPREADING; CHARACTERISATION; DETECTION EFFICIENCIES; DETECTOR EFFICIENCY; IRRADIATION EXPERIMENTS; LIVING CELLS; MEV PROTONS; NUCLEAR MICROPROBE; SINGLE CELLS; SINGLE IONS; TARGETING ACCURACIES; THIN SILICON DETECTOR; VACUUM WINDOW; VACUUM WINDOWS;

DETECTORS;

EID: 54049101943     PISSN: 0168583X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nimb.2008.07.011     Document Type: Article

References (19)

1. Folkard M., Vojnovic B., Prise K.M., Bowey A.G., Locke R.J., Schettino G., and Michael B.D. A charged-particle microbeam: I. Development of an experimental system for targeting cells individually with counted particles. Int. J. Radiat. Biol. 72 (1997) 375
2. Folkard M., Vojnovic B., Hollis K.J., Bowey A.G., Watts S.J., Schettino G., Prise K.M., and Michael B.D. A charged-particle microbeam: II. A single-particle micro-collimation and detection system. Int. J. Radiat. Biol. 72 (1997) 387
3. Heiss M., Fischer B.E., Jakob B., Fournier C., Becker G., and Taucher-Scholz G. Targeted irradiation of mammalian cells using a heavy-ion microprobe. Radiat. Res. 165 (2006) 231
4. Bigelow A.W., Ross G.J., Randers-Pehrson G., and Brenner D.J. The Columbia University microbeam II endstation for cell imaging and irradiation. Nucl. Instr. and Meth. B 231 (2005) 202
5. Fischer B.E., Heiss M., and Cholewa M. About the art to shoot with single ions. Nucl. Instr. and Meth. B 210 (2003) 285
6. Barberet Ph., Balana A., Incerti S., Michelet-Habchi C., Moretto Ph., and Pouthier Th. Development of a focused charged particle microbeam for the irradiation of individual cells. Rev. Sci. Instr. 76 (2004) 015101
7. Folkard M., Vojnovic B., Gilchrist S., Prise K.M., and Michael B.D. The design and application of ion microbeams for irradiating living cells and tissues. Nucl. Instr. and Meth. B 210 (2003) 302
8. Greif K.D., Brede H.J., Frankenberg D., and Giesen U. The PTB single ion microbeam for irradiation of living cells. Nucl. Instr. and Meth. B 217 (2004) 505
9. Polak W., Veselov O., Lekki J., Stachura Z., Zazula M., Ugenskiene R., Polak M., and Styczen J. Irradiating single cells using Cracow microprobe facility. Nucl. Instr. and Meth. B 249 (2006) 743
10. Reinert T., Fiedler A., Skopek J., Tanner J., Vogt J., and Butz T. Single ion bombardment of living cells at LIPSION. Nucl. Instr. and Meth. B 219-220 (2004) 77
11. Hauptner A., Dietzel S., Drexler G.A., Reichart P., Krücken R., Cremer T., Friedl A.A., and Dollinger G. Microirradiation of cells with energetic heavy ions. Radiat. Environ. Biophys. 42 (2005) 237-245
12. Arteaga-Marrero N., Pallon J., Olsson M.G., Auzelyte V., Elfman M., Kristiansson P., Malmqvist K., Nilsson C., and Wegdén M. The new cell irradiation facility at the Lund Nuclear Probe. Nucl. Instr. and Meth. B 260 (2007) 91
13. Nilsson Ch., Pallon J., Thungström G., Arteaga N., Auzelyte V., Elfman M., Kristiansson P., Nilsson C., and Wegdén M. Evaluation of a pre-cell hit detector for the future single ion hit facility in Lund. Nucl. Instr. and Meth. B 249 (2006) 924
14. Thungström G., Westerberg L., Spohr R., and Petersson C.S. Fabrication and characterization of thin ΔE detectors for spectroscopic application. Nucl. Instr. and Meth. A 546 (2005) 312
15. J.F. Ziegler, SRIM 2006, Version SRIM-2006.01, .
16. Elfman M., Pallon J., Auzelyte V., Kristiansson P., Malmqvist K., Nilsson C., Shariff A., and Wegdén M. The Lund nuclear microprobe sub-micron set-up, part III: Sample stage, optical imaging and detector configuration in the experimental chamber. Nucl. Instr. and Meth. B 231 (2005) 14
17. Shariff A., Auzelyte V., Elfman M., Kristiansson P., Malmqvist K., Nilsson C., Pallon J., and Wegdén M. The Lund nuclear microprobe sub-micron set-up. Part I: Ion optics calculation. Nucl. Instr. and Meth. B 231 (2005) 1
18. Siegele R., Reinhard M., Prokopovich D., Ionescu M., Cohen D.D., Rosenfeld A.B., Cornelius I.M., Wroe A., Lerch M.L.F., Fazzi A., Pola A., and Agosteo S. Characterisation of a ΔE-E particle telescope using the ANSTO heavy ion microprobe. Nucl. Instr. and Meth. B 270 (2007) 270
19. GeoPIXE II, .