Long-term resistance training improves force and unloaded shortening velocity of single muscle fibres of elderly women

European Journal of Applied Physiology

Volumn 104, Issue 5, 2008, Pages 885-893

  Parente, Valeria ^a,b   D'Antona, Giuseppe ^a   Adami, Raffaella ^a   Miotti, Danilo ^c   Capodaglio, Paolo ^d   de Vito, Giuseppe ^e   Bottinelli, Roberto ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b CENTRO CARDIOLOGICO MONZINO   (Italy)

^c IRCCS   (Italy)

^d ISTITUTO AUXOLOGICO ITALIANO   (Italy)

^e UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Ageing; Exercise training; Humans; Myosin isoforms; Skinned fibres

Indexed keywords

ISOPROTEIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2;

AGED; ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; ISOMETRIC EXERCISE; MUSCLE BIOPSY; MUSCLE EXERCISE; MUSCLE FORCE; MUSCLE FUNCTION; MUSCLE TRAINING; NORMAL HUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN LOCALIZATION; QUADRICEPS FEMORIS MUSCLE; SKELETAL MUSCLE; VASTUS LATERALIS MUSCLE; VELOCITY;

ADAPTATION, PHYSIOLOGICAL; AGED; AGED, 80 AND OVER; FEMALE; HUMANS; MUSCLE CONTRACTION; MUSCLE FIBERS, SKELETAL; MUSCLE STRENGTH; MYOSIN HEAVY CHAINS; PROTEIN ISOFORMS; QUADRICEPS MUSCLE; RESISTANCE TRAINING;

EID: 54049091893     PISSN: 14396319     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00421-008-0845-0     Document Type: Article

References (63)

1. Aagaard P, Andersen JL, Dyhre-Poulsen P, Leffers AM, Wagner A, Magnusson SP, Halkjaer-Kristensen J, Simonsen EB (2001) A mechanism for increased contractile strength of human pennate muscle in response to strength training: Changes in muscle architecture. J Physiol 534:613-623
2. Adams GR, Hather BM, Baldwin KM, Dudley GA (1993) Skeletal muscle myosin heavy chain composition and resistance training. J Appl Physiol 74:911-915
3. Alway SE, Grumbt WH, Gonyea WJ, Stray-Gundersen J (1989) Contrasts in muscle and myofibers of elite male and female bodybuilders. J Appl Physiol 67:24-31
4. Andersen JL, Klitgaard H, Bangsbo J, Saltin B (1994) Myosin heavy chain isoforms in single fibres from m. vastus lateralis of soccer players: effects of strength-training. Acta Physiol Scand 150:21-26
5. Atherton PJ, Babraj J, Smith K, Singh J, Rennie MJ, Wackerhage H (2005) Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. Faseb J 19:786-788
6. Balagopal P, Rooyackers OE, Adey DB, Ades PA, Nair KS (1997) Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol 273:E790-E800
7. Bergstrom J (1962) Muscle electrolytes in man. Scand J Clin Lab Invest Suppl 68:1-110
8. Bottinelli R (2001) Functional heterogeneity of mammalian single muscle fibres: Do myosin isoforms tell the whole story? Pflugers Arch 443:6-17
9. Bottinelli R, Reggiani C (2000) Human skeletal muscle fibres: Molecular and functional diversity. Prog Biophys Mol Biol 73:195-262
10. Bottinelli R, Schiaffino S, Reggiani C (1991) Force-velocity relations and myosin heavy chain isoform compositions of skinned fibres from rat skeletal muscle. J Physiol 437:655-672
11. Bottinelli R, Betto R, Schiaffino S, Reggiani C (1994) Unloaded shortening velocity and myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibres. J Physiol 478(Pt 2):341-349
12. Bottinelli R, Canepari M, Pellegrino MA, Reggiani C (1996) Force-velocity properties of human skeletal muscle fibres: Myosin heavy chain isoform and temperature dependence. J Physiol (Lond) 495:573-586
13. Brenner B (1983) Technique for stabilizing the striation pattern in maximally calcium-activated skinned rabbit psoas fibers. Biophys J 41:99-102
14. Canepari M, Rossi R, Pellegrino MA, Bottinelli R, Schiaffino S, Reggiani C (2000) Functional diversity between orthologous myosins with minimal sequence diversity. J Muscle Res Cell Motil 21:375-382
15. Canepari M, Rossi R, Pellegrino MA, Orrell RW, Cobbold M, Harridge S, Bottinelli R (2005) Effects of resistance training on myosin function studied by the in vitro motility assay in young and older men. J Appl Physiol 98:2390-2395
16. Capodaglio P, Capodaglio Edda M, Facioli M, Saibene F (2007) Long-term strength training for community-dwelling people over 75: Impact on muscle function, functional ability and life style. Eur J Appl Physiol 100:535-542
17. Colliander EB, Tesch PA (1990) Effects of eccentric and concentric muscle actions in resistance training. Acta Physiol Scand 140:31-39
18. D'Antona G, Pellegrino MA, Adami R, Rossi R, Carlizzi CN, Canepari M, Saltin B, Bottinelli R (2003) The effect of ageing and immobilization on structure and function of human skeletal muscle fibres. J Physiol 552:499-511
19. D'Antona G, Lanfranconi F, Pellegrino MA, Brocca L, Adami R, Rossi R, Moro G, Miotti D, Canepari M, Bottinelli R (2006) Skeletal muscle hypertrophy and structure and function of skeletal muscle fibres in male body builders. J Physiol 570:611-627
20. D'Antona G, Pellegrino MA, Carlizzi CN, Bottinelli R (2007) Deterioration of contractile properties of muscle fibres in elderly subjects is modulated by the level of physical activity. Eur J Appl Physiol 100:603-611
21. Feder G, Cryer C, Donovan S, Carter Y (2000) Guidelines for the prevention of falls in people over 65. The guidelines' development group. BMJ 321:1007-1011
22. Ferri A, Scaglioni G, Pousson M, Capodaglio P, Van Hoecke J, Narici MV (2003) Strength and power changes of the human plantar flexors and knee extensors in response to resistance training in old age. Acta Physiol Scand 177:69-78
23. Fluck M, Hoppeler H (2003) Molecular basis of skeletal muscle plasticity-from gene to form and function. Rev Physiol Biochem Pharmacol 146:159-216
24. Frontera WR, Meredith CN, O'Reilly KP, Knuttgen HG, Evans WJ (1988) Strength conditioning in older men: Skeletal muscle hypertrophy and improved function. J Appl Physiol 64:1038-1044
25. Fry AC (2004) The role of resistance exercise intensity on muscle fibre adaptations. Sports Med 34:663-679
26. Godt RE, Maughan DW (1977) Swelling of skinned muscle fibers of the frog. Experimental observations. Biophys J 19:103-116
27. Hakkinen K, Kallinen M, Izquierdo M, Jokelainen K, Lassila H, Malkia E, Kraemer WJ, Newton RU, Alen M (1998a) Changes in agonist-antagonist EMG, muscle CSA, and force during strength training in middle-aged and older people. J Appl Physiol 84:1341-1349
28. Hakkinen K, Newton RU, Gordon SE, McCormick M, Volek JS, Nindl BC, Gotshalk LA, Campbell WW, Evans WJ, Hakkinen A, Humphries BJ, Kraemer WJ (1998b) Changes in muscle morphology, electromyographic activity, and force production characteristics during progressive strength training in young and older men. J Gerontol A Biol Sci Med Sci 53:B415-B423
29. Hameed M, Orrell RW, Cobbold M, Goldspink G, Harridge SD (2003) Expression of IGF-I splice variants in young and old human skeletal muscle after high resistance exercise. J Physiol 547:247-254
30. Harridge SDR, Bottinelli R, Canepari M, Pellegrino MA, Reggiani C, Esbjornsson M, Saltin B (1996) Whole-muscle and single-fibre contractile properties and myosin heavy chain isoforms in humans. Pflugers Arch 432:913-920
31. Harridge SD, Kryger A, Stensgaard A (1999) Knee extensor strength, activation, and size in very elderly people following strength training. Muscle Nerve 22:831-839
32. Hartman JW, Moore DR, Phillips SM (2006) Resistance training reduces whole-body protein turnover and improves net protein retention in untrained young males. Appl Physiol Nutr Metabol 31:557-564
33. Hook P, Sriramoju V, Larsson L (2001) Effects of aging on actin sliding speed on myosin from single skeletal muscle cells of mice, rats, and humans. Am J Physiol Cell Physiol 280:C782-C788
34. Ingalls CP (2004) Nature vs. nurture: Can exercise really alter fiber type composition in human skeletal muscle? J Appl Physiol 97:1591-1592
35. Laemmli UK (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685
36. Larsson L, Moss RL (1993) Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. J Physiol 472:595-614
37. Larsson L, Grimby G, Karlsson J (1979) Muscle strength and speed of movement in relation to age and muscle morphology. J Appl Physiol 46:451-456
38. Larsson L, Li X, Frontera WR (1997) Effects of aging on shortening velocity and myosin isoform composition in single human skeletal muscle cells. Am J Physiol 272:C638-C649
39. Liu Y, Schlumberger A, Wirth K, Schmidtbleicher D, Steinacker JM (2003) Different effects on human skeletal myosin heavy chain isoform expression: Strength vs. combination training. J Appl Physiol 94:2282-2288
40. Macaluso A, De Vito G (2004) Muscle strength, power and adaptations to resistance training in older people. Eur J Appl Physiol 91:450-472
41. Martel GF, Roth SM, Ivey FM, Lemmer JT, Tracy BL, Hurlbut DE, Metter EJ, Hurley BF, Rogers MA (2006) Age and sex affect human muscle fibre adaptations to heavy-resistance strength training. Exp Physiol 91:457-464
42. Moore DR, Phillips SM, Babraj JA, Smith K, Rennie MJ (2005) Myofibrillar and collagen protein synthesis in human skeletal muscle in young men after maximal shortening and lengthening contractions. Am J Physiol Endocrinol Metab 288:E1153-E1159
43. Morganti CM, Nelson ME, Fiatarone MA, Dallal GE, Economos CD, Crawford BM, Evans WJ (1995) Strength improvements with 1 yr of progressive resistance training in older women. Med Sci Sports Exerc 27:906-912
44. Narici MV, Roi GS, Landoni L, Minetti AE, Cerretelli P (1989) Changes in force, cross-sectional area and neural activation during strength training and detraining of the human quadriceps. Eur J Appl Physiol Occup Physiol 59:310-319
45. Narici MV, Hoppeler H, Kayser B, Landoni L, Claassen H, Gavardi C, Conti M, Cerretelli P (1996) Human quadriceps cross-sectional area, torque and neural activation during 6 months strength training. Acta Physiol Scand 157:175-186
46. Narici MV, Reeves ND, Morse CI, Maganaris CN (2004) Muscular adaptations to resistance exercise in the elderly. J Musculoskelet Neuronal Interact 4:161-164
47. Pellegrino MA, Canepari M, Rossi R, D'Antona G, Reggiani C, Bottinelli R (2003) Orthologous myosin isoforms and scaling of shortening velocity with body size in mouse, rat, rabbit and human muscles. J Physiol 546:677-689
48. Reeves ND, Maganaris CN, Narici MV (2003) Effect of strength training on human patella tendon mechanical properties of older individuals. J Physiol 548:971-981
49. Reeves ND, Narici MV, Maganaris CN (2004) Effect of resistance training on skeletal muscle-specific force in elderly humans. J Appl Physiol 96:885-892
50. Reeves ND, Narici MV, Maganaris CN (2006) Myotendinous plasticity to ageing and resistance exercise in humans. Exp Physiol 91:483-498
51. Satta A, Migliori GB, Spanevello A, Neri M, Bottinelli R, Canepari M, Pellegrino MA, Reggiani C (1997) Fibre types in skeletal muscles of chronic obstructive pulmonary disease patients related to respiratory function and exercise tolerance. Eur Respir J 10:2853-2860
52. Scaglioni G, Ferri A, Minetti AE, Martin A, Van Hoecke J, Capodaglio P, Sartorio A, Narici MV (2002) Plantar flexor activation capacity and H reflex in older adults: Adaptations to strength training. J Appl Physiol 92:2292-2302
53. Skelton DA, Young A, Greig CA, Malbut KE (1995) Effects of resistance training on strength, power, and selected functional abilities of women aged 75 and older. J Am Geriatr Soc 43:1081-1087
54. Skelton DA, Kennedy J, Rutherford OM (2002) Explosive power and asymmetry in leg muscle function in frequent fallers and non-fallers aged over 65. Age Ageing 31:119-125
55. Trappe S, Williamson D, Godard M, Porter D, Rowden G, Costill D (2000) Effect of resistance training on single muscle fiber contractile function in older men. J Appl Physiol 89:143-152
56. Trappe S, Godard M, Gallagher P, Carroll C, Rowden G, Porter D (2001) Resistance training improves single muscle fiber contractile function in older women. Am J Physiol Cell Physiol 281:C398-C406
57. Trappe S, Gallagher P, Harber M, Carrithers J, Fluckey J, Trappe T (2003) Single muscle fibre contractile properties in young and old men and women. J Physiol 552:47-58
58. Wernbom M, Augustsson J, Thomee R (2007) The influence of frequency, intensity, volume and mode of strength training on whole muscle cross-sectional area in humans. Sports Med 37:225-264
59. Whipple RH, Wolfson LI, Amerman PM (1987) The relationship of knee and ankle weakness to falls in nursing home residents: An isokinetic study. J Am Geriatr Soc 35:13-20
60. Widrick JJ, Stelzer JE, Shoepe TC, Garner DP (2002) Functional properties of human muscle fibers after short-term resistance exercise training. Am J Physiol Regul Integr Comp Physiol 283:R408-R416
61. Yarasheski KE (2003) Exercise, aging, and muscle protein metabolism. J Gerontol A Biol Sci Med Sci 58:M918-M922
62. Young A, Stokes M, Crowe M (1985) The size and strength of the quadriceps muscles of old and young men. Clin Physiol 5:145-154
63. Yu F, Hedstrom M, Cristea A, Dalen N, Larsson L (2007) Effects of ageing and gender on contractile properties in human skeletal muscle and single fibres. Acta Physiol (Oxf) 190(3):229-241