Effects of ageing and gender on contractile properties in human skeletal muscle and single fibres

Acta Physiologica

Volumn 190, Issue 3, 2007, Pages 229-241

  Yu, F ^a   Hedstrom M ^b   Cristea, A ^c   Dalen N ^d   Larsson, L ^a,c  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

^d DANDERYD HOSPITAL   (Sweden)

Author keywords

Maximum velocity of unloaded shortening; Muscle mass; Skinned fibres; Slack test; Specific tension; Torque velocity

Indexed keywords

PROTEIN; PROTEIN MYHC I; PROTEIN MYHC II; UNCLASSIFIED DRUG;

ADULT; AGED; AGING; ARTICLE; EXTENSOR MUSCLE; FEMALE; HUMAN; HUMAN TISSUE; IN VIVO STUDY; KNEE; MALE; MUSCLE CELL; MUSCLE CONTRACTION; MUSCLE FUNCTION; MUSCLE WEAKNESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SEX DIFFERENCE; SKELETAL MUSCLE; STATISTICAL SIGNIFICANCE; TORQUE;

ADULT; AGED; AGING; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE PROTEINS; MUSCLE, SKELETAL; SEX CHARACTERISTICS;

EID: 34250626145     PISSN: 17481708     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1748-1716.2007.01699.x     Document Type: Article

References (61)

1. Balagopal, P. 1997. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol 273, E790 E800.
2. Blake, A.J., Morgan, K., Bendall, M.J., Dallosso, H., Ebrahim, S.B., Arie, T.H., Fentem, P.H. Bassey, E.J. 1988. Falls by elderly people at home: prevalence and associated factors. Age Ageing 17, 365 372.
3. D'Antona, G., Pellegrino, M.A., Adami, R., Rossi, R., Carlizzi, C.N., Canepari, M., Saltin, B. Bottinelli, R. 2003. The effect of ageing and immobilization on structure and function of human skeletal muscle fibres. J Physiol 552, 499 511.
4. Degens, H., Yu, F., Li, X. Larsson, L. 1998. Effects of age and gender on shortening velocity and myosin isoforms in single rat muscle fibres. Acta Physiol Scand 163, 33 40.
5. Degens, H., Soop, M., Hook, P., Ljungqvist, O. Larsson, L. 1999. Post-operative effects on insulin resistance and specific tension of single human skeletal muscle fibres. Clin Sci (Colch) 97, 449 455.
6. Delbono, O., Renganathan, M. Messi, M.L. 1997. Excitation-Ca2+ release-contraction coupling in single aged human skeletal muscle fiber. Muscle Nerve Suppl 5, S88 S92.
7. Dubowitz, V. 1985. Muscle Biopsy: A Practical Approach. Tindal & Cox, London, Bailliere.
8. Edman, K.A. 1979. The velocity of unloaded shortening and its relation to sarcomere length and isometric force in vertebrate muscle fibres. J Physiol (Lond) 291, 143 159.
9. Fabiato, A. 1988. Computer programs for calculating total from specified free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol 157, 378 417.
10. Fitts, R.H., Costill, D.L. Gardetto, P.R. 1989. Effect of swim exercise training on human muscle fiber function. J Appl Physiol 66, 465 475.
11. Frontera, W.R. Larsson, L. 1997. Contractile studies of single human skeletal muscle fibers: a comparison of different muscles, permeabilization procedures, and storage techniques. Muscle Nerve 20, 948 952.
12. Gransberg, L. Knutsson, E. 1983. Determination of dynamic muscle strength in man with acceleration controlled isokinetic movements. Acta Physiol Scand 119, 317 320.
13. Greaser, M.L., Moss, R.L. Reiser, P.J. 1988. Variations in contractile properties of rabbit single muscle fibres in relation to troponin T isoforms and myosin light chains. J Physiol (Lond) 406, 85 98.
14. Gur, H., Gransberg, L., van Dyke, D., Knutsson, E. Larsson, L. 2003. Relationship between in vivo muscle force at different speeds of isokinetic movements and myosin isoform expression in men and women. Eur J Appl Physiol 88, 487 496.
15. Harper, M.E., Bevilacqua, L., Hagopian, K., Weindruch, R. Ramsey, J.J. 2004. Ageing, oxidative stress, and mitochondrial uncoupling. Acta Physiol Scand 182, 321 331.
16. Hemenway, D., Solnick, S.J., Koeck, C. Kytir, J. 1994. The incidence of stairway injuries in Austria. Accid Anal Prev 26, 675 679.
17. Hill, A.V. 1950. The dimensions of animals and their muscular dynamics. Sci Prog 38, 209 230.
18. Hofmann, P.A., Greaser, M.L. Moss, R.L. 1991a. C-protein limits shortening velocity of rabbit skeletal muscle fibres at low levels of Ca2+ activation. J Physiol (Lond) 439, 701 715.
19. Hofmann, P.A., Hartzell, H.C. Moss, R.L. 1991b. Alterations in Ca2+ sensitive tension due to partial extraction of C- protein from rat skinned cardiac myocytes and rabbit skeletal muscle fibers. J Gen Physiol 97, 1141 1163.
20. Hook, P., Li, X., Sleep, J., Hughes, S. Larsson, L. 1999. In vitro motility speed of slow myosin extracted from single soleus fibres from young and old rats. J Physiol (Lond) 520 (Pt 2 463 471.
21. Hook, P., Sriramoju, V. Larsson, L. 2001. Effects of aging on actin sliding speed on myosin from single skeletal muscle cells of mice, rats, and humans. Am J Physiol Cell Physiol 280, C782 C788.
22. Jakubiec-Puka, A. 1992. Changes in myosin and actin filaments in fast skeletal muscle after denervation and self-reinnervation. Comp Biochem Physiol Comp Physiol 102, 93 98.
23. Korhonen, M.T., Cristea, A., Alen, M., Hakkinen, K., Sipila, S., Mero, A., Viitasalo, J.T., Larsson, L. Suominen, H. 2006. Aging, muscle fiber type and contractile function in sprint-trained athletes. J Appl Physiol 101, 906 917.
24. Krivickas, L.S., Suh, D., Wilkins, J., Hughes, V.A., Roubenoff, R. Frontera, W.R. 2001. Age- and gender-related differences in maximum shortening velocity of skeletal muscle fibers. Am J Phys Med Rehabil 80, 447 455 quiz 456-7.
25. Larsson, L. 1982a. Ageing in Mammalian Skeletal Muscles. Praeger, New York.
26. Larsson, L. 1982b. Physical training effects on muscle morphology in sedentary males at different ages. Med Sci Sports Exerc 14, 203 206.
27. Larsson, L. 1990. A technique for measuring contractile properties in single chemically skinned human fibres obtained from percutaneous biopsies. J Neurol Sci 98, 430.
28. Larsson, L. Ansved, T. 1995. Effects of ageing on the motor unit. Prog Neurobiol 45, 397 458.
29. Larsson, L. Moss, R.L. 1993. Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. J Physiol (Lond) 472, 595 614.
30. Larsson, L. Salviati, G. 1992. A technique for studies of the contractile apparatus in single human muscle fibre segments obtained by percutaneous biopsy. Acta Physiol Scand 146, 485 495.
31. Larsson, L. Skogsberg, C. 1988. Effects of the interval between removal and freezing of muscle biopsies on muscle fibre size. J Neurol Sci 85, 27 38.
32. Larsson, L., Sjodin, B. Karlsson, J. 1978. Histochemical and biochemical changes in human skeletal muscle with age in sedentary males, age 22-65 years. Acta Physiol Scand 103, 31 39.
33. Larsson, L., Skogsberg, C. Gur, H. 1990. Influence of the interval between removal and freezing of muscle samples on muscle fibre size with special reference to sample size and fibre type. Acta Physiol Scand 139, 451 458.
34. Larsson, L., Biral, D., Campione, M. Schiaffino, S. 1993. An age-related type IIB to IIX myosin heavy chain switching in rat skeletal muscle. Acta Physiol Scand 147, 227 234.
35. Larsson, L., Li, X., Berg, H.E. Frontera, W.R. 1996. Effects of removal of weight-bearing function on contractility and myosin isoform composition in single human skeletal muscle cells. Pflugers Arch 432, 320 328.
36. Larsson, L., Li, X. Frontera, W.R. 1997a. Effects of aging on shortening velocity and myosin isoform composition in single human skeletal muscle cells. Am J Physiol 272, C638 C649.
37. Larsson, L., Li, X., Yu, F. Degens, H. 1997b. Age-related changes in contractile properties and expression of myosin isoforms in single skeletal muscle cells. Muscle Nerve Suppl 5, S74 S78.
38. Larsson, L., Li, X., Edstrom, L., Eriksson, L.I., Zackrisson, H., Argentini, C. Schiaffino, S. 2000. Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: mechanisms at the cellular and molecular levels [see comments]. Crit Care Med 28, 34 45.
39. Lexell, J. 1995. Human aging, muscle mass, and fiber type composition. J Gerontol A Biol Sci Med Sci 50 (Spec No 11 16.
40. Li, X. Larsson, L. 1996. Maximum shortening velocity and myosin isoforms in single muscle fibers from young and old rats. Am J Physiol 270, C352 C360.
41. Lowe, D.A., Surek, J.T., Thomas, D.D. Thompson, L.V. 2001. Electron paramagnetic resonance reveals age-related myosin structural changes in rat skeletal muscle fibers. Am J Physiol Cell Physiol 280, C540 C547.
42. Mahoney, J., Sager, M., Dunham, N.C. Johnson, J. 1994. Risk of falls after hospital discharge. J Am Geriatr Soc 42, 269 274.
43. Mahoney, J.E., Sager, M.A. Jalaluddin, M. 1999. Use of an ambulation assistive device predicts functional decline associated with hospitalization. J Gerontol A Biol Sci Med Sci 54, M83 M88.
44. Marx, J.O., Kraemer, W.J., Nindl, B.C. Larsson, L. 2002. Effects of aging on human skeletal muscle myosin heavy-chain mRNA content and protein isoform expression. J Gerontol A Biol Sci Med Sci 57, B232 B238.
45. Moisescu, D.G. Thieleczek, R. 1978. Calcium and strontium concentration changes within skinned muscle preparations following a change in the external bathing solution. J Physiol (Lond) 275, 241 262.
46. Mooradian, A.D. Wong, N.C. 1991. Molecular biology of aging. Part II: A synopsis of current research. J Am Geriatr Soc 39, 717 723.
47. Moss, R.L. 1979. Sarcomere length-tension relations in frog skinned muscle fibres during calcium activation at short lengths. J Physiol 292, 177 192.
48. Nevitt, M.C., Cummings, S.R. Hudes, E.S. 1991. Risk factors for injurious falls: a prospective study. J Gerontol 46, M164 M170.
49. Ochala, J., Li, M., Tajsharghi, H., Kimber, E., Oldfors, A. Larsson, L. 2007. Effects of a beta-tropomyosin mutation on regulation of contraction in single human skeletal muscle fibres (in press).
50. Phillips, S.K., Wiseman, R.W., Woledge, R.C. Kushmerick, M.J. 1993. Neither changes in phosphorus metabolite levels nor myosin isoforms can explain the weakness in aged mouse muscle. J Physiol 463, 157 167.
51. Rantanen, T., Era, P. Heikkinen, E. 1994. Maximal isometric strength and mobility among 75-year-old men and women. Age Ageing 23, 132 137.
52. Robbins, A.S., Rubenstein, L.Z., Josephson, K.R., Schulman, B.L., Osterweil, D. Fine, G. 1989. Predictors of falls among elderly people. Results of two population-based studies. Arch Intern Med 149, 1628 1633.
53. Sarwar, R., Niclos, B.B. Rutherford, O.M. 1996. Changes in muscle strength, relaxation rate and fatiguability during the human menstrual cycle. J Physiol 493 (Pt 1 267 272.
54. Schultz, A.B., Ashton-Miller, J.A. Alexander, N.B. 1997. What leads to age and gender differences in balance maintenance and recovery? Muscle Nerve Suppl 5, S60 S64.
55. Seligman, A.M., Karnovsky, M.J., Wasserkrug, H.L. Hanker, J.S. 1968. Nondroplet ultrastructural demonstration of cytochrome oxidase activity with a polymerizing osmiophilic reagent, diaminobenzidine (DAB). J Cell Biol 38, 1 14.
56. Thompson, L.V. Brown, M. 1999. Age-related changes in contractile properties of single skeletal fibers from the soleus muscle. J Appl Physiol 86, 881 886.
57. Tomonaga, M. 1977. Histochemical and ultrastructural changes in senile human skeletal muscle. J Am Geriatr Soc 25, 125 131.
58. Trappe, S., Gallagher, P., Harber, M., Carrithers, J., Fluckey, J. Trappe, T. 2003. Single muscle fibre contractile properties in young and old men and women. J Physiol 552, 47 58.
59. Wattanapermpool, J. Reiser, P.J. 1999. Differential effects of ovariectomy on calcium activation of cardiac and soleus myofilaments. Am J Physiol 277, H467 H473.
60. Whipple, R.H., Wolfson, L.I. Amerman, P.M. 1987. The relationship of knee and ankle weakness to falls in nursing home residents: an isokinetic study. J Am Geriatr Soc 35, 13 20.
61. Yu, F., Degens, H., Li, X. Larsson, L. 1998. Gender- and age-related differences in the regulatory influence of thyroid hormone on the contractility and myosin composition of single rat soleus muscle fibres. Pflugers Arch 437, 21 30.