Effects of resistance training on myosin function studied by the in vitro motility assay in young and older men

Journal of Applied Physiology

Volumn 98, Issue 6, 2005, Pages 2390-2395

  Canepari, M ^a,c   Rossi, R ^a   Pellegrino, M A ^a,c   Orrell, R W ^b   Cobbold, M ^b   Harridge, S ^b   Bottinelli, R ^a,c  

^a UNIVERSITY OF PAVIA   (Italy)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c Interuniversity Institute of Myology   (Italy)

Author keywords

Myosin isoforms; Velocity of shortening

Indexed keywords

ISOPROTEIN; MYOSIN; MYOSIN HEAVY CHAIN; MYOSIN HEAVY CHAIN 2A; MYOSIN HEAVY CHAIN 2X; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; EXTENSOR MUSCLE; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; IN VITRO STUDY; KNEE FUNCTION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN ISOLATION; SKELETAL MUSCLE; TRAINING; VASTUS LATERALIS MUSCLE; VELOCITY;

ADAPTATION, PHYSIOLOGICAL; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; EXERCISE; EXERTION; HUMANS; MALE; MECHANOTRANSDUCTION, CELLULAR; MUSCLE CONTRACTION; MUSCLE FIBERS; MUSCLE, SKELETAL; MYOSIN HEAVY CHAINS; PROTEIN ISOFORMS;

EID: 19444365072     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.01103.2004     Document Type: Article

References (44)

1. Aagaard P, Andersen JL, Dyhre-Poulsen P, Leffers AM, Wagner A, Magnusson SP, Halkjaer-Kristensen J, and Simonsen EB. A mechanism for increased contractile strength of human pennate muscle in response to strength training: changes in muscle architecture. J Physiol 534: 613-623, 2001.
2. Andersen JL, Klitgaard H, and Saltin B. Myosin heavy chain isoforms in single fibres from m. vastus lateralis of sprinters: influence of training. Acta Physiol Scand 151: 135-142, 1994.
3. Anson M, Drummond DR, Geeves MA, Hennessey ES, Ritchie MD, and Sparrow JC. Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene. Biophys J 68: 1991-2003, 1995.
4. Aoyagi Y and Shephard RJ. Aging and muscle function. Sports Med 14: 376-396, 1992.
5. Avigad G, Kniep A, and Bailin G. Reaction of rabbit skeletal myosin with D-glucose 6-phosphate. Biochem Mol Biol Int 40: 273-284, 1996.
6. Balagopal P, Rooyackers OE, Adey DB, Ades PA, and Nair KS. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol Endocrinol Metab 273: E790-E800, 1997.
7. Bergstrom J. Muscle electrolytes in man. Scand J Clin Lab Invest Suppl 68: 1-110, 1962.
8. Bottinelli R. Functional heterogeneity of mammalian single muscle fibres: do myosin isoforms tell the whole story? Pflügers Arch 443: 6-17, 2001.
9. Bottinelli R, Betto R, Schiaffino S, and Reggiani C. Unloaded shortening velocity and myosin heavy chain and alkali light chain isoform composition in rat skeletal muscle fibres. J Physiol 478: 341-349, 1994.
10. Bottinelli R and Reggiani C. Human skeletal muscle fibres: molecular and functional diversity. Prog Biophys Mol Biol 73: 195-262, 2000.
11. Campbell MJ, McComas AJ, and Petito F. Physiological changes in ageing muscles. J Neurol Neurosurg Psychiatry 36: 174-182, 1973.
12. Canepari M, Rossi R, Pellegrino MA, Bottinelli R, Schiaffino S, and Reggiani C. Functional diversity between orthologous myosins with minimal sequence diversity. J Muscle. Res Cell Motil 21: 375-382, 2000.
13. Canepari M, Rossi R, Pellegrino MA, Reggiani C, and Bottinelli R. Speeds of actin translocation in vitro by myosins extracted from single rat muscle fibres of different types. Exp Physiol 84: 803-806, 1999.
14. D'Antona G, Pellegrino MA, Adami R, Rossi R, Carlizzi CN, Canepari M, Saltin B, and Bottinelli R. The effect of ageing and immobilization on structure and function of human skeletal muscle fibres. J Physiol 552: 499-511, 2003.
15. Fauteck SP and Kandarian SC. Sensitive detection of myosin heavy chain composition in skeletal muscle under different loading conditions. Am J Physiol Cell Physiol 268: C419-C424, 1995.
16. Fiatarone MA, Marks EC, Ryan ND, Meredith CN, Lipsitz LA, and Evans WJ. High-intensity strength training in nonagenarians. Effects on skeletal muscle. JAMA 263: 3029-3034, 1990.
17. Fluck M and Hoppeler H. Molecular basis of skeletal muscle plasticity - from gene to form and function. Rev Physiol Biochem Pharmacol 146: 159-216, 2003.
18. Frontera WR, Hughes VA, Fielding RA, Fiatarone MA, Evans WJ, and Roubenoff R. Aging of skeletal muscle: a 12-yr longitudinal study. J Appl Physiol 88: 1321-1326, 2000.
19. Frontera WR, Meredith CN, O'Reilly KP, Knuttgen HG, and Evans WJ. Strength conditioning in older men: skeletal muscle hypertrophy and improved function. J Appl Physiol 64: 1038-1044, 1988.
20. Galler S, Hilber K, Gohlsch B, and Pette D. Two functionally distinct myosin heavy chain isoforms in slow skeletal muscle fibres. FEBS Lett 410: 150-152, 1997.
21. Greig CA, Young A, Skelton DA, Pippet E, Butler FM, and Mahmud SM. Exercise studies with elderly volunteers. Age Ageing 23: 185-189, 1994.
22. Harridge SD, Bottinelli R, Canepari M, Pellegrino M, Reggiani C, Esbjornsson M, Balsom PD, and Saltin B. Sprint training, in vitro and in vivo muscle function, and myosin heavy chain expression. J Appl Physiol 84: 442-449, 1998.
23. Harridge SDR, Bottinelli R, Canepari M, Pellegrino MA, Reggiani C, Esbjornsson M, and Saltin B. Whole-muscle and single-fibre contractile properties and myosin heavy chain isoforms in humans. Pflügers Arch 432: 913-920, 1996.
24. Hook P, Li X, Sleep J, Hughes S, and Larsson L. In vitro motility speed of slow myosin extracted from single soleus fibres from young and old rats. J Physiol 520: 463-471, 1999.
25. Hook P, Sriramoju V, and Larsson L. Effects of aging on actin sliding speed on myosin from single skeletal muscle cells of mice, rats, and humans. Am J Physiol Cell Physiol 280: C782-C788, 2001.
26. Hughes SM, Cho M, Karsch-Mizrachi I, Travis M, Silberstein L, Leinwand LA, and Blau HM. Three slow myosin heavy chains sequentially expressed in developing mammalian skeletal muscle. Dev Biol 158: 183-199, 1993.
27. Klitgaard H, Zhou M, Schiaffino S, Betto R, Salviati G, and Saltin B. Ageing alters the myosin heavy chain composition of single fibres from human skeletal muscle. Acta Physiol Scand 140: 55-62, 1990.
28. Larsson L, Li X, and Frontera WR. Effects of aging on shortening velocity and myosin isoform composition in single human skeletal muscle cells. Am J Physiol Cell Physiol 272: C638-C649, 1997.
29. Larsson L and Moss RL. Maximum velocity of shortening in relation to myosin isoform composition in single fibres from human skeletal muscles. J Physiol 472: 595-614, 1993.
30. Lexell J. Human aging, muscle mass, and fiber type composition. J Gerontol A Biol Sci Med Sci 50 Spec No: 11-16, 1995.
31. Lexell J, Taylor CC, and Sjostrom M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15- to 83-year-old men. J Neurol Sci 84: 275-294, 1988.
32. Liu Y, Lormes W, Reissnecker S, and Steinacker JM. Effects of high intensity resistance and low intensity endurance training on myosin heavy chain isoform expression in highly trained rowers. Int J Sports Med 24: 264-270, 2003.
33. Ramamurthy B, Hook P, Jones AD, and Larsson L. Changes in myosin structure and function in response to glycation. FASEB J 15: 2415-2422, 2001.
34. Ramamurthy B, Jones AD, and Larsson L. Glutathione reverses early effects of glycation on myosin function. Am J Physiol Cell Physiol 285: C419-C424, 2003.
35. Sweeney HL, Bowman BF, and Stull JT. Myosin light chain phosphorylation in vertebrate striated muscle: regulation and function. Am J Physiol Cell Physiol 264: C1085-C1095, 1993.
36. Sweeney HL, Kushmerick MJ, Mabuchi K, Sreter FA, and Gergely J. Myosin alkali light chain and heavy chain variations correlate with altered shortening velocity of isolated skeletal muscle fibers. J Biol Chem 263: 9034-9039, 1988.
37. Trappe S, Costill D, and Thomas R. Effect of swim taper on whole muscle and single muscle fiber contractile properties. Med Sci Sports Exerc 32: 48-56, 2000.
38. Trappe S, Gallagher P, Harber M, Carrithers J, Fluckey J, and Trappe T. Single muscle fibre contractile properties in young and old men and women. J Physiol 552: 47-58, 2003.
39. Trappe S, Godard M, Gallagher P, Carroll C, Rowden G, and Porter D. Resistance training improves single muscle fiber contractile function in older women. Am J Physiol Cell Physiol 281: C398-C406, 2001.
40. Trappe S, Williamson D, Godard M, Porter D, Rowden G, and Costill D. Effect of resistance training on single muscle fiber contractile function in older men. J Appl Physiol 89: 143-152, 2000.
41. Widrick JJ, Knuth ST, Norenberg KM, Romatowski JG, Bain JL, Riley DA, Karhanek M, Trappe SW, Trappe TA, Costill DL, and Fitts RH. Effect of a 17 day spaceflight on contractile properties of human soleus muscle fibres. J Physiol 516: 915-930, 1999.
42. Widrick JJ, Stelzer JE, Shoepe TC, and Garner DP. Functional properties of human muscle fibers after short-term resistance exercise training. Am J Physiol Regul Integr Comp Physiol 283: R408-R416, 2002.
43. Widrick JJ, Trappe SW, Blaser CA, Costill DL, and Fitts RH. Isometric force and maximal shortening velocity of single muscle fibers from elite master runners. Am J Physiol Cell Physiol 271: C666-C675, 1996.
44. Williamson DL, Godard MP, Porter DA, Costill DL, and Trappe SW. Progressive resistance training reduces myosin heavy chain coexpression in single muscle fibers from older men. J Appl Physiol 88: 627-633, 2000.