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Volumn 9, Issue 9, 2008, Pages 747-756

Switching from suppressive protease inhibitor-based regimens to nevirapine-based regimens: A meta-analysis of randomized controlled trials

Author keywords

Antiretroviral therapy highly active; Meta analysis; Nevirapine; Protease inhibitors

Indexed keywords

AMPRENAVIR PLUS RITONAVIR; ANTIRETROVIRUS AGENT; EFAVIRENZ; INDINAVIR; INDINAVIR PLUS RITONAVIR; LOPINAVIR PLUS RITONAVIR; NELFINAVIR; NEVIRAPINE; PROTEINASE INHIBITOR; RITONAVIR; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; SAQUINAVIR PLUS RITONAVIR; UNCLASSIFIED DRUG;

EID: 54049090424     PISSN: 14642662     EISSN: 14681293     Source Type: Journal    
DOI: 10.1111/j.1468-1293.2008.00627.x     Document Type: Article
Times cited : (19)

References (40)
  • 1
    • 0037006623 scopus 로고    scopus 로고
    • Association between the presence of HLA-B*5701, HLA-DR7 and HLA-DQ3 and hypersensitivity to HIV-1 reverse transcriptase inhibitor abacavir
    • Mallal S, Nolan E, Witt C et al. Association between the presence of HLA-B*5701, HLA-DR7 and HLA-DQ3 and hypersensitivity to HIV-1 reverse transcriptase inhibitor abacavir. Lancet 2002; 359: 727-732.
    • (2002) Lancet , vol.359 , pp. 727-732
    • Mallal, S.1    Nolan, E.2    Witt, C.3
  • 2
    • 33745295856 scopus 로고    scopus 로고
    • Prospective genetic screening decreases the incidence of abacavir hypersensitivity in the Western Australian HIV Cohort Study
    • Rauch A, Nolan D, Martin A et al. Prospective genetic screening decreases the incidence of abacavir hypersensitivity in the Western Australian HIV Cohort Study. Clin Infect Dis 2006; 43: 99-102.
    • (2006) Clin Infect Dis , vol.43 , pp. 99-102
    • Rauch, A.1    Nolan, D.2    Martin, A.3
  • 3
    • 0036569234 scopus 로고    scopus 로고
    • A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection
    • Opravil M, Hirschel B, Lazzarin A et al. A randomized trial of simplified maintenance therapy with abacavir, lamivudine, and zidovudine in human immunodeficiency virus infection. J Infect Dis 2002; 185: 1251-1260.
    • (2002) J Infect Dis , vol.185 , pp. 1251-1260
    • Opravil, M.1    Hirschel, B.2    Lazzarin, A.3
  • 4
    • 0042387870 scopus 로고    scopus 로고
    • Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection
    • Martinez E, Arnaiz JA, Podzamczer D et al. Substitution of nevirapine, efavirenz, or abacavir for protease inhibitors in patients with human immunodeficiency virus infection. N Engl J Med 2003; 349: 1036-1046.
    • (2003) N Engl J Med , vol.349 , pp. 1036-1046
    • Martinez, E.1    Arnaiz, J.A.2    Podzamczer, D.3
  • 5
    • 33846587991 scopus 로고    scopus 로고
    • Three-year follow-up of protease inhibitor-based regimen simplification in HIV-infected patients
    • Martinez E, Arnaiz JA, Podzamczer D et al. Three-year follow-up of protease inhibitor-based regimen simplification in HIV-infected patients. AIDS 2007; 21: 367-369.
    • (2007) AIDS , vol.21 , pp. 367-369
    • Martinez, E.1    Arnaiz, J.A.2    Podzamczer, D.3
  • 6
    • 33750999952 scopus 로고    scopus 로고
    • Efavirenz and chronic neuropsychiatric symptoms: A cross-sectional case control study
    • Rihs TA, Begley K, Smith DE et al. Efavirenz and chronic neuropsychiatric symptoms: A cross-sectional case control study. HIV Med 2006; 7: 544-548.
    • (2006) HIV Med , vol.7 , pp. 544-548
    • Rihs, T.A.1    Begley, K.2    Smith, D.E.3
  • 7
    • 33745902228 scopus 로고    scopus 로고
    • Depressive symptoms predict increased incidence of neuropsychiatric side effects in patients treated with efavirenz
    • Boly L, Cafaro V, Dyner T. Depressive symptoms predict increased incidence of neuropsychiatric side effects in patients treated with efavirenz. J Acquir Immune Defic Syndr 2006; 42: 514-515.
    • (2006) J Acquir Immune Defic Syndr , vol.42 , pp. 514-515
    • Boly, L.1    Cafaro, V.2    Dyner, T.3
  • 8
    • 2642534354 scopus 로고    scopus 로고
    • Efavirenz-associated gynecomastia: Report of five cases and review of the literature
    • Jover F, Cuadrado JM, Roig P, Rodriguez M, Andreu L, Merino J. Efavirenz-associated gynecomastia: Report of five cases and review of the literature. Breast J 2004; 10: 244-246.
    • (2004) Breast J , vol.10 , pp. 244-246
    • Jover, F.1    Cuadrado, J.M.2    Roig, P.3    Rodriguez, M.4    Andreu, L.5    Merino, J.6
  • 9
    • 15744367156 scopus 로고    scopus 로고
    • Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naïve patients infected with HIV-1
    • van Leth F, Phanuphak P, Stroes E et al. Nevirapine and efavirenz elicit different changes in lipid profiles in antiretroviral-therapy-naïve patients infected with HIV-1. PLoS Med 2004; 1: E19.
    • (2004) PLoS Med , vol.1
    • van Leth, F.1    Phanuphak, P.2    Stroes, E.3
  • 10
    • 11144357656 scopus 로고    scopus 로고
    • Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: A randomised open-label trial, the 2NN Study
    • van Leth F, Phanuphak P, Ruxrungtham K et al. Comparison of first-line antiretroviral therapy with regimens including nevirapine, efavirenz, or both drugs, plus stavudine and lamivudine: A randomised open-label trial, the 2NN Study. Lancet 2004; 363: 1253-1263.
    • (2004) Lancet , vol.363 , pp. 1253-1263
    • van Leth, F.1    Phanuphak, P.2    Ruxrungtham, K.3
  • 11
    • 4744353225 scopus 로고    scopus 로고
    • Long-term efficacy and safety of protease inhibitor switching to nevirapine in HIV-infected patients with undetectable virus load
    • Gil P, de Gorgolas M, Estrada V et al. Long-term efficacy and safety of protease inhibitor switching to nevirapine in HIV-infected patients with undetectable virus load. Clin Infect Dis 2004; 39: 1024-1029.
    • (2004) Clin Infect Dis , vol.39 , pp. 1024-1029
    • Gil, P.1    de Gorgolas, M.2    Estrada, V.3
  • 12
    • 0032903844 scopus 로고    scopus 로고
    • Reversion of metabolic abnormalities after switching from HIV-1 protease inhibitors to nevirapine
    • Martinez E, Conget I, Lozano L, Casamitjana R, Gatell JM. Reversion of metabolic abnormalities after switching from HIV-1 protease inhibitors to nevirapine. AIDS 1999; 13: 805-810.
    • (1999) AIDS , vol.13 , pp. 805-810
    • Martinez, E.1    Conget, I.2    Lozano, L.3    Casamitjana, R.4    Gatell, J.M.5
  • 13
    • 20644467776 scopus 로고    scopus 로고
    • Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine
    • Fisac C, Fumero E, Crespo M et al. Metabolic benefits 24 months after replacing a protease inhibitor with abacavir, efavirenz or nevirapine. AIDS 2005; 19: 917-925.
    • (2005) AIDS , vol.19 , pp. 917-925
    • Fisac, C.1    Fumero, E.2    Crespo, M.3
  • 14
    • 3042592251 scopus 로고    scopus 로고
    • Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection
    • Tebas P, Yarasheski K, Henry K et al. Evaluation of the virological and metabolic effects of switching protease inhibitor combination antiretroviral therapy to nevirapine-based therapy for the treatment of HIV infection. AIDS Res Hum Retroviruses 2004; 20: 589-594.
    • (2004) AIDS Res Hum Retroviruses , vol.20 , pp. 589-594
    • Tebas, P.1    Yarasheski, K.2    Henry, K.3
  • 15
    • 0242690222 scopus 로고    scopus 로고
    • Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patients
    • Ena J, Amador C, Benito C, Fenoll V, Pasquau F. Risk and determinants of developing severe liver toxicity during therapy with nevirapine-and efavirenz-containing regimens in HIV-infected patients. Int J STD AIDS 2003; 14: 776-781.
    • (2003) Int J STD AIDS , vol.14 , pp. 776-781
    • Ena, J.1    Amador, C.2    Benito, C.3    Fenoll, V.4    Pasquau, F.5
  • 16
    • 0242364714 scopus 로고    scopus 로고
    • Risk of severe hepatotoxicity associated with antiretroviral therapy in the HIV-NAT Cohort, Thailand, 1996-2001
    • Law WP, Dore GJ, Duncombe CJ et al. Risk of severe hepatotoxicity associated with antiretroviral therapy in the HIV-NAT Cohort, Thailand, 1996-2001. AIDS 2003; 17: 2191-2199.
    • (2003) AIDS , vol.17 , pp. 2191-2199
    • Law, W.P.1    Dore, G.J.2    Duncombe, C.J.3
  • 17
    • 0036139688 scopus 로고    scopus 로고
    • Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: Role of hepatitis C and B infections
    • Sulkowski MS, Thomas DL, Mehta SH, Chaisson RE, Moore RD. Hepatotoxicity associated with nevirapine or efavirenz-containing antiretroviral therapy: Role of hepatitis C and B infections. Hepatology 2002; 35: 182-189.
    • (2002) Hepatology , vol.35 , pp. 182-189
    • Sulkowski, M.S.1    Thomas, D.L.2    Mehta, S.H.3    Chaisson, R.E.4    Moore, R.D.5
  • 19
    • 0032450165 scopus 로고    scopus 로고
    • DRESS (Drug rash with eosinophilia and systemic symptoms) syndrome associated with nevirapine therapy
    • Bourezanne Y, Salard D, Hoen B, Vandel S, Drobasheff C, Laurent R. DRESS (Drug rash with eosinophilia and systemic symptoms) syndrome associated with nevirapine therapy. Clin Infect Dis 1998; 27: 1321-1322.
    • (1998) Clin Infect Dis , vol.27 , pp. 1321-1322
    • Bourezanne, Y.1    Salard, D.2    Hoen, B.3    Vandel, S.4    Drobasheff, C.5    Laurent, R.6
  • 20
    • 54049092103 scopus 로고    scopus 로고
    • Accessed 20 July
    • Boehringer-Ingelheim: http://www.Boehringer-ingelheim.com/hiv/prod/ login.htm. Accessed 20 July, 2007.
    • (2007) Boehringer-Ingelheim
  • 21
    • 0033610734 scopus 로고    scopus 로고
    • Improving the quality of reports of meta-analyses of randomised controlled trials: The QUOROM Statement
    • Moher D, Cook DJ for the QUOROM Group et al. Improving the quality of reports of meta-analyses of randomised controlled trials: The QUOROM Statement. Lancet 1999; 354: 1896-1900.
    • (1999) Lancet , vol.354 , pp. 1896-1900
    • Moher, D.1    Cook, D.J.2
  • 22
    • 0029914622 scopus 로고    scopus 로고
    • Assessing the quality of reports of randomized clinical trials: Is blinding necessary?
    • Jadad AR, Moore RA, Carroll D et al. Assessing the quality of reports of randomized clinical trials: Is blinding necessary? Control Clin Trials 1996; 17: 1-12.
    • (1996) Control Clin Trials , vol.17 , pp. 1-12
    • Jadad, A.R.1    Moore, R.A.2    Carroll, D.3
  • 23
    • 0030693603 scopus 로고    scopus 로고
    • Quantitative synthesis in systematic reviews
    • Lau J, Ioannidis JP, Schmid CH. Quantitative synthesis in systematic reviews. Ann Intern Med 1997; 127: 820-826.
    • (1997) Ann Intern Med , vol.127 , pp. 820-826
    • Lau, J.1    Ioannidis, J.P.2    Schmid, C.H.3
  • 24
    • 0028659004 scopus 로고
    • Operating characteristics of a rank correlation test for publication bias
    • Begg CB, Mazumdar M. Operating characteristics of a rank correlation test for publication bias. Biometrics 1994; 50: 1088-1101.
    • (1994) Biometrics , vol.50 , pp. 1088-1101
    • Begg, C.B.1    Mazumdar, M.2
  • 25
    • 25144477970 scopus 로고    scopus 로고
    • A randomized controlled trial investigating the efficacy and safety of switching from a protease inhibitor to nevirapine in patients with undetectable viral load
    • Arranz Caso JA, Lopez JC, Santos I et al. A randomized controlled trial investigating the efficacy and safety of switching from a protease inhibitor to nevirapine in patients with undetectable viral load. HIV Med 2005; 6: 353-359.
    • (2005) HIV Med , vol.6 , pp. 353-359
    • Arranz Caso, J.A.1    Lopez, J.C.2    Santos, I.3
  • 26
    • 0034106517 scopus 로고    scopus 로고
    • Risks and benefits of replacing protease inhibitors by nevirapine in HIV-infected subjects under long-term successful triple combination therapy
    • Barreiro P, Soriano V, Blanco F, Casimiro C, de la Cruz JJ, Gonzalez-Lahoz J. Risks and benefits of replacing protease inhibitors by nevirapine in HIV-infected subjects under long-term successful triple combination therapy. AIDS 2000; 14: 807-812.
    • (2000) AIDS , vol.14 , pp. 807-812
    • Barreiro, P.1    Soriano, V.2    Blanco, F.3    Casimiro, C.4    de la Cruz, J.J.5    Gonzalez-Lahoz, J.6
  • 27
    • 21844480420 scopus 로고    scopus 로고
    • Substitution of nevirapine or efavirenz for protease inhibitor vs. lipid-lowering therapy for the management of dyslipidaemia
    • Calza L, Manfredi R, Colangeli V et al. Substitution of nevirapine or efavirenz for protease inhibitor vs. lipid-lowering therapy for the management of dyslipidaemia. AIDS 2005; 19: 1051-1058.
    • (2005) AIDS , vol.19 , pp. 1051-1058
    • Calza, L.1    Manfredi, R.2    Colangeli, V.3
  • 28
    • 0037024758 scopus 로고    scopus 로고
    • Reversal of atherogenic lipoprotein profile in HIV-1-infected patients with lipodystrophy after replacing protease inhibitors by nevirapine
    • Negredo E, Ribalta J, Paredes R et al. Reversal of atherogenic lipoprotein profile in HIV-1-infected patients with lipodystrophy after replacing protease inhibitors by nevirapine. AIDS 2002; 16: 1383-1389.
    • (2002) AIDS , vol.16 , pp. 1383-1389
    • Negredo, E.1    Ribalta, J.2    Paredes, R.3
  • 29
    • 0037082965 scopus 로고    scopus 로고
    • Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression
    • Negredo E, Cruz L, Paredes R et al. Virological, immunological, and clinical impact of switching from protease inhibitors to nevirapine or to efavirenz in patients with human immunodeficiency virus infection and long-lasting viral suppression. Clin Infect Dis 2002; 34: 504-510.
    • (2002) Clin Infect Dis , vol.34 , pp. 504-510
    • Negredo, E.1    Cruz, L.2    Paredes, R.3
  • 30
    • 0035393524 scopus 로고    scopus 로고
    • Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with HIV-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled study
    • Ruiz L, Negredo E, Domingo P et al. Antiretroviral treatment simplification with nevirapine in protease inhibitor-experienced patients with HIV-associated lipodystrophy: 1-year prospective follow-up of a multicenter, randomized, controlled study. J Acquir Immune Defic Syndr 2001; 27: 229-236.
    • (2001) J Acquir Immune Defic Syndr , vol.27 , pp. 229-236
    • Ruiz, L.1    Negredo, E.2    Domingo, P.3
  • 31
    • 1642294551 scopus 로고    scopus 로고
    • Meta-analysis of randomized controlled trials of simplified vs. continued protease-inhibitor-based antiretroviral therapy in HIV-1-infected patients
    • Bucher HC, Kofler A, Nüesch R, Young J, Battegay M, Opravil M. Meta-analysis of randomized controlled trials of simplified vs. continued protease-inhibitor-based antiretroviral therapy in HIV-1-infected patients. AIDS 2003; 17: 2451-2459.
    • (2003) AIDS , vol.17 , pp. 2451-2459
    • Bucher, H.C.1    Kofler, A.2    Nüesch, R.3    Young, J.4    Battegay, M.5    Opravil, M.6
  • 32
    • 0035816360 scopus 로고    scopus 로고
    • Hepatotoxicity in HIV-1-infected patients receiving nevirapine-containing antiretroviral therapy
    • Martínez E, Blanco JL, Arnaiz JA et al. Hepatotoxicity in HIV-1-infected patients receiving nevirapine-containing antiretroviral therapy. AIDS 2001; 15: 1261-1268.
    • (2001) AIDS , vol.15 , pp. 1261-1268
    • Martínez, E.1    Blanco, J.L.2    Arnaiz, J.A.3
  • 33
    • 0037111556 scopus 로고    scopus 로고
    • A cohort study of nevirapine tolerance in clinical practice: French Aquitaine Cohort, 1997-1999
    • Bonnet F, Lawson-Ayayi S, Thiébaut R et al. A cohort study of nevirapine tolerance in clinical practice: French Aquitaine Cohort, 1997-1999. Clin Infect Dis 2002; 35: 1231-1237.
    • (2002) Clin Infect Dis , vol.35 , pp. 1231-1237
    • Bonnet, F.1    Lawson-Ayayi, S.2    Thiébaut, R.3
  • 34
    • 34248219982 scopus 로고    scopus 로고
    • Reasons for discontinuation of nevirapine-containing HAART: Results from an unselected population of a large clinical cohort
    • Maggiolo F, Arici C, Airoldi M et al. Reasons for discontinuation of nevirapine-containing HAART: Results from an unselected population of a large clinical cohort. J Antimicrob Chemother 2007; 59: 569-572.
    • (2007) J Antimicrob Chemother , vol.59 , pp. 569-572
    • Maggiolo, F.1    Arici, C.2    Airoldi, M.3
  • 35
    • 34249054728 scopus 로고    scopus 로고
    • Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naïve and -experienced HIV-infected patients with high and low CD4 T-cell counts
    • Mocroft A, Staszewski S, Weber R et al. Risk of discontinuation of nevirapine due to toxicities in antiretroviral-naïve and -experienced HIV-infected patients with high and low CD4 T-cell counts. Antivir Ther 2007; 12: 325-333.
    • (2007) Antivir Ther , vol.12 , pp. 325-333
    • Mocroft, A.1    Staszewski, S.2    Weber, R.3
  • 36
    • 34548056370 scopus 로고    scopus 로고
    • Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting
    • Kumarasamy N, Venkatesh KK, Devaleenal B et al. Safety of switching to nevirapine-based highly active antiretroviral therapy at elevated CD4 cell counts in a resource-constrained setting. J Acquir Immune Defic Syndr 2007; 45: 598-600.
    • (2007) J Acquir Immune Defic Syndr , vol.45 , pp. 598-600
    • Kumarasamy, N.1    Venkatesh, K.K.2    Devaleenal, B.3
  • 37
    • 33846442010 scopus 로고    scopus 로고
    • Switching strategies to improve lipid profile and morphologic changes
    • Barragan P, Fisac C, Podzamczer D. Switching strategies to improve lipid profile and morphologic changes. AIDS Rev 2006; 8: 191-203.
    • (2006) AIDS Rev , vol.8 , pp. 191-203
    • Barragan, P.1    Fisac, C.2    Podzamczer, D.3
  • 38
    • 4344683480 scopus 로고    scopus 로고
    • Health-related quality of life in HIV-infected naïve patients treated with nelfinavir or nevirapine associated with ZDV/3TC (the COMBINE-QoL substudy)
    • Casado A, Badia X, Consiglio E et al. Health-related quality of life in HIV-infected naïve patients treated with nelfinavir or nevirapine associated with ZDV/3TC (the COMBINE-QoL substudy). HIV Clin Trials 2004; 5: 132-139.
    • (2004) HIV Clin Trials , vol.5 , pp. 132-139
    • Casado, A.1    Badia, X.2    Consiglio, E.3
  • 39
    • 0035958773 scopus 로고    scopus 로고
    • Overview of the effectiveness of triple combination therapy in antiretroviral-naïve HIV-1-infected adults
    • Bartlett JA, DeMasi R, Quinn J, Moxham C, Rousseau F. Overview of the effectiveness of triple combination therapy in antiretroviral-naïve HIV-1-infected adults. AIDS 2001; 15: 1369-1377.
    • (2001) AIDS , vol.15 , pp. 1369-1377
    • Bartlett, J.A.1    DeMasi, R.2    Quinn, J.3    Moxham, C.4    Rousseau, F.5


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