Synthesis and biological evaluation of the Zn (II)-IDB complexes appended with oligopolyamide as potent artificial nuclease

Bioorganic and Medicinal Chemistry Letters

Volumn 18, Issue 21, 2008, Pages 5766-5770

  Li, Chao ^a   Qiao, Ren Zhong ^a   Wang, Ya Qin ^a   Zhao, Yu Fen ^b   Zeng, Rong ^c  

^a BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY   (China)

^b TSINGHUA UNIVERSITY   (China)

^c JINAN UNIVERSITY   (China)

Author keywords

DNA cleavage; IDB; Polyamide; Synthesis; Zn (II) complex

Indexed keywords

ADENINE; AMINE; BENZIMIDAZOLE DERIVATIVE; BIS(2 BENZIMIDAZOLYLMETHYL)AMINE; NUCLEASE; OLIGOMER; PLASMID DNA; POLYAMIDE; THYMINE; UNCLASSIFIED DRUG; ZINC COMPLEX;

AGAR GEL ELECTROPHORESIS; ARTICLE; AT RICH SEQUENCE; CONJUGATION; DNA CLEAVAGE; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; ELECTROSPRAY MASS SPECTROMETRY; INFRARED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; BENZIMIDAZOLES; CATTLE; DEOXYRIBONUCLEASE I; DNA; ELECTROPHORESIS, AGAR GEL; NYLONS; ORGANOMETALLIC COMPOUNDS; SPECTROPHOTOMETRY, ULTRAVIOLET; ZINC;

EID: 53949107174     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2008.09.074     Document Type: Article

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