Antagonistic interactions between the flavonoids hesperetin and naringenin and β-lactam antibiotics against Staphylococcus aureus

British Journal of Biomedical Science

Volumn 65, Issue 3, 2008, Pages 145-147

  Denny, Brian J ^a   West, P W J ^a   Mathew, T C ^a  

^a KUWAIT UNIVERSITY   (Kuwait)

Author keywords

Electron microscopy; Methicillin resistance; Microbial sensitivity tests; Staphylococcus aureus

Indexed keywords

BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; CEFOXITIN; HESPERETIN; METICILLIN; NARINGENIN; OXACILLIN; PENICILLIN BINDING PROTEIN; PENICILLIN G;

ANTIBACTERIAL ACTIVITY; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIUM ISOLATE; CONTROLLED STUDY; DRUG ANTAGONISM; ELECTRON MICROSCOPY; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 53849142541     PISSN: 09674845     EISSN: None     Source Type: Journal    
DOI: 10.1080/09674845.2008.11732819     Document Type: Article

References (19)

1. Herrmann K. Flavonols and flavones in plants: a review. J Food Technol 1976; 11: 433-48.
2. Qin GW, Xu RS. Recent advances on bioactive natural products from Chinese medicinal plants. Med Res Rev 1998; 18: 37542.
3. Cushnie TPT, Lamb AJ. Antimicrobial activity of flavonoids. Int J Antimicrob Agents 2005; 26: 343-56.
4. Rice-Evans CA, Miller NJ. Antioxidant activities of flavonoids as bioactive components of food. Biochem Soc Trans 1996; 24: 790-5.
5. Choi SU, Ryu SY, Yoon SK et al. Effects of flavonoids on the growth and cell cycle of cancer cells. Anticancer Res 1999; 19 (6B): 5229-33.
6. Berger-Bachi B, Rohrer S. Factors influencing methicillin resistance in staphylococci. Arch Microbiol 2002; 178: 165-71.
7. Fluit AC, Visser MR, Schmitz F-J. Molecular detection of antimicrobial resistance. Clin Microbiol Rev 2001; 14: 836-71.
8. West PWJ, Mathew TC, Miller NJ, Electricwala Q. The effect of green tea on the growth and morphology of methicillin-resistant and methicillin-susceptible Staphylococcus aureus. J Nutr Environ Med 2001; 11: 263-69.
9. Stapleton PD, Shah S, Ehlert K, Hara Y, Taylor PW. The β-lactam-resistance modifier (-)-epicatechin gallate alters the architecture of the cell wall of Staphylococcus aureus. Microbiology 2007; 153: 2093-103.
10. Erlund I, Silaste ML, Alfthan G, Rantala M, Kesantemi YA, Aro A. Plasma concentrations of the flavonoids hesperetin, naringenin and quercetin in human subjects following their habitual diets and diets high or low in fruit and vegetables. Eur J Clin Nutr 2002; 56: 891-8.
11. Fujita M, Shiota S, Kuroda T et al. Remarkable synergies between baicalein and tetracycline, and baicalein and beta-lactams against methicillin-resistant Staphylococcus aureus. Microbiol Immunol 2005; 49: 391-6.
12. Cauwelier B, Gordts B, Descheemaecker P, Van Landuyt H. Evaluation of a disk diffusion method with cefoxitin (30 microg) for detection of methicillin-resistant Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 2004; 23: 389-92.
13. National Committee for Clinical Laboratory Standards. Methods for determining bactericidal activity of antimicrobial agents; Approved guideline (M26-A). Wayne PA: NCCLS, 2000; Vol. 19.
14. Park KM, You JS, Lee M Baek NI, Hwang JK. Kuwanon G: an antimicrobial agent from the root bark of Morus alba against oral pathogens. J Ethnopharmacol 2003; 84: 181-5.
15. Hamilton-Miller JMT, Shah S. Disorganization of cell division of methicillin-resistant Staphylococcus aureus by a component of tea (Camellia sinensis): a study by electron microscopy. FEMS Microbiol Lett 1999; 176: 463-9.
16. Zhao WH, Hu ZQ, Hara Y, Shimamura T. Inhibition of penicillinase by epicatechin gallate resulting in restoration of antibacterial activity of penicillin against penicillinase-producing Staphylococcus aureus. Antimicrob Agents Chemother 2002; b 46: 2266-8.
17. Yam TS, Hamilton-Miller JM, Shah S. The effect of a component of tea ( Camellia sinensis) on methicillin resistance, PBP2′ synthesis and β-lactamase production in Staphylococcus aureus. J Antimicrob Chemother 1998; 42: 211-6.
18. Zhao WH, Hu ZQ, Okubo, Hara SY, Shimamura T. Mechanism of synergy between epicatechin gallate and β-lactams against methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2001; 45: 1737-42.
19. National Committee for Clinical Laboratory Standards. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; Approved guideline (M7-A5) Wayne PA: NCCLS, 2000: Vol. 20.