Manipulation of corticosteroid release from a transiently supersaturated topical metered dose aerosol using a residual miscible co-solvent

Pharmaceutical Research

Volumn 25, Issue 11, 2008, Pages 2573-2580

  Reid, Monica L ^a   Brown, Marc B ^b,c   Jones, Stuart A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

^c MEDPHARM LTD   (United Kingdom)

Author keywords

Aerosol; Beclomethasone dipropionate; Corticosteroids; Diffusion; In vitro models; Percutaneous drug delivery; Solubility; Supersaturation

Indexed keywords

ALCOHOL; BECLOMETASONE DIPROPIONATE; CORTICOSTEROID; MACROGOL; MACROGOL 400; NORFLURANE; POVIDONE; SOLVENT;

ADHESION; AEROSOL; ARTICLE; CRYSTALLIZATION; DRUG FORMULATION; DRUG RELEASE; EVAPORATION; KINETICS; METERED DOSE AEROSOL; MISCIBILITY; PRIORITY JOURNAL;

AEROSOLS; BECLOMETHASONE; ETHANOL; HYDROCARBONS, FLUORINATED; METERED DOSE INHALERS; POLYETHYLENE GLYCOLS; POVIDONE; SOLUBILITY;

EID: 53849104256     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9675-3     Document Type: Article

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