Effect of concentration and degree of saturation of topical fluocinonide formulations on in vitro membrane transport and in vivo availability on human skin

Pharmaceutical Research

Volumn 16, Issue 6, 1999, Pages 909-915

  Schwarb, Fabian P ^a   Imanidis, Georgios ^b   Smith, Eric W ^c   Haigh, John M ^d   Surber, Christian ^a  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b UNIVERSITY OF BASEL   (Switzerland)

^c OHIO NORTHERN UNIVERSITY   (United States)

^d RHODES UNIVERSITY   (South Africa)

Author keywords

Fluocinonide, in vivo in vitro correlation; Human skin blanching assay; Percutaneous penetration; Silicone membrane; Supersaturation; Topical availability

Indexed keywords

CORTICOSTEROID; FLUOCINONIDE; POVIDONE;

ARTICLE; DRUG BINDING; DRUG BIOAVAILABILITY; DRUG CONCENTRATION; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG FORMULATION; HUMAN; HUMAN EXPERIMENT; MEMBRANE TRANSPORT; NORMAL HUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; SKIN; STRATUM CORNEUM; THERMODYNAMICS; TOPICAL DRUG ADMINISTRATION;

ADMINISTRATION, TOPICAL; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL TRANSPORT; CELL MEMBRANE PERMEABILITY; CHEMISTRY, PHARMACEUTICAL; ETHANOL; FLUOCINONIDE; GLUCOCORTICOIDS; GLYCEROL; HUMANS; PROPYLENE GLYCOL; SKIN; SKIN ABSORPTION; SOLUTIONS; WATER;

EID: 0033021230     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1018890422825     Document Type: Article

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