Effect of transforming growth factor-alpha on enterocyte apoptosis is correlated with EGF receptor expression along the villus-crypt axis during methotrexate-induced intestinal mucositis in a rat

Apoptosis

Volumn 13, Issue 11, 2008, Pages 1344-1355

  Sukhotnik, Igor ^a,b   Shteinberg, Dan ^a   Ben Lulu, Shani ^a   Bashenko, Yulia ^a   Mogilner, Jorge G ^b   Ure, Benno M ^c   Shaoul, Ron ^b   Coran, Arnold G ^d  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b BNAI ZION MEDICAL CENTER   (Israel)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF MICHIGAN   (United States)

Author keywords

EGFr; Enterocyte apoptosis; Enterocyte proliferation; Intestine; Methotrexate; TGF

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; METHOTREXATE; PROTEIN BAX; PROTEIN BCL 2; TRANSFORMING GROWTH FACTOR ALPHA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; ENTEROPATHY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; INTESTINAL MUCOSITIS; INTESTINE CELL; INTESTINE VILLUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CACO-2 CELLS; ENTEROCYTES; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL MUCOSA; MALE; METHOTREXATE; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; TRANSFORMING GROWTH FACTOR ALPHA;

RATTUS;

EID: 53849101371     PISSN: 13608185     EISSN: 1573675X     Source Type: Journal    
DOI: 10.1007/s10495-008-0258-x     Document Type: Article

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