Improved synthesis of a new nonpeptidic inhibitor of human neutrophil elastase

Synlett

Volumn , Issue 2, 2001, Pages 299-301

  Ohmoto, K ^a   Yamamoto, T ^a   Horiuchi, T ^a   Kojima, T ^a   Hachiya, K ^a   Hashimoto, S ^a   Kawamura, M ^a   Nakai, H ^a   Toda, M ^a  

^a ONO PHARMACEUTICAL CO   (Japan)

Author keywords

Aminopyrimidinone; Anionic addition reaction; Enzyme inhibitor; Ketooxadiazole; Lossen rearrangement

Indexed keywords

2 (5 AMINO 6 OXO 2 PHENYLHYDROPYRIMIDINYL) N [2 (5 TERT BUTYL 1,3,4 OXADIAZOL 2 YL) 1 (METHYLETHYL) 2 OXOETHYL]ACETAMIDE; LEUKOCYTE ELASTASE INHIBITOR; ONO 6818; OXADIAZOLE DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL STRUCTURE; SYNTHESIS;

EID: 0035125164     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-10786     Document Type: Article

References (10)