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32
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53749083107
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A study to determine whether the higher yield of the Heck product in the case of 7-benzyl-6-iodopurine is a result of the steric hindrance of the benzyl group or due to the different electronic distribution in 7-benzyl-6-iodopurine is now being undertaken in our laboratory
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A study to determine whether the higher yield of the Heck product in the case of 7-benzyl-6-iodopurine is a result of the steric hindrance of the benzyl group or due to the different electronic distribution in 7-benzyl-6-iodopurine is now being undertaken in our laboratory.
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33
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53749085794
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Interestingly, only traces of the corresponding Heck product were detected if the used reaction conditions were applied in the reactions between 6-chloro-8-iodo-9-isopropylpurine and butyl acrylate or styrene. Optimization of the reaction conditions to achieve Heck reactions of 8-halopurines will thus require further study.
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Interestingly, only traces of the corresponding Heck product were detected if the used reaction conditions were applied in the reactions between 6-chloro-8-iodo-9-isopropylpurine and butyl acrylate or styrene. Optimization of the reaction conditions to achieve Heck reactions of 8-halopurines will thus require further study.
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35
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0033041709
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M. Legraverend, O. Ludwig, E. Bisagni, S. Leclerc, L. Meijer, N. Giocanti, R. Sadri, V. Favaudon, Bioorg. Med. Chem. 1999, 7, 1281-1293.
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Legraverend, M.1
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Sadri, R.7
Favaudon, V.8
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37
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19544377674
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[2] does not mention compound 5d.
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[2] does not mention compound 5d.
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