Increased duodenal expression of transforming growth factor-αand epidermal growth factor during experimental colitis in rats

European Journal of Gastroenterology and Hepatology

Volumn 20, Issue 10, 2008, Pages 989-994

  Bulut, Kerem ^a   Felderbauer, Peter ^a,b   Hoeck, Karoline ^b   Schmidt, Wolfgang E ^a   Hoffmann, Peter ^b  

^a ST JOSEF HOSPITAL   (Germany)

^b KLINIKEN ESSEN MITTE   (Germany)

Author keywords

Epidermal growth factor; Experimental model of colitis; Gastrointestinal nervous system; Transforming growth factor alpha

Indexed keywords

ALCOHOL; EPIDERMAL GROWTH FACTOR; MESSENGER RNA; TRANSFORMING GROWTH FACTOR ALPHA; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON; COLON MUCOSA; DUODENUM; DUODENUM MUCOSA; EXPERIMENTAL STUDY; GASTROINTESTINAL MUCOSA; GASTROINTESTINAL TRACT; ILEUM; JEJUNUM; MALE; MOLECULAR DYNAMICS; NONHUMAN; PRIORITY JOURNAL; PROTECTION; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STOMACH; SUBMANDIBULAR GLAND; UPREGULATION;

ANIMALS; COLITIS; COLON; DUODENUM; EPIDERMAL GROWTH FACTOR; ETHANOL; GENE EXPRESSION; INTESTINAL MUCOSA; MALE; MODELS, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR ALPHA; TRINITROBENZENESULFONIC ACID;

EID: 53549133359     PISSN: 0954691X     EISSN: None     Source Type: Journal    
DOI: 10.1097/MEG.0b013e3283036758     Document Type: Article

References (43)

1. Carpenter G, Cohen S. Epidermal growth factor. Annu Rev Biochem 1979; 48:193-216.
2. Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991; 251:936-939.
3. Shoyab M, Plowman GD, McDonald VL, Bradley JG, Todaro GJ. Structure and function of human amphiregulin: a member of the epidermal growth factor family. Science 1989; 243:1074-1076.
4. De Larco JE, Todaro GJ. Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci U S A 1978; 75:4001-4005.
5. Cartlidge SA, Elder JB. Transforming growth factor alpha and epidermal growth factor levels in normal human gastrointestinal mucosa. Br J Cancer 1989;60:657-660.
6. Miettinen PJ, Perheentupa J, Otonkoski T, Lahteenmaki A, Panula P. EGF- and TGF-alpha-like peptides in human fetal gut. Pediatr Res 1989; 26:25-30.
7. Schaudies RP, Grimes J, Davis D, Rao RK, Koldovsky O. EGF content in the gastrointestinal tract of rats: effect of age and fasting/feeding. Am J Physiol 1989; 256:G856-G861.
8. Perez-Tomas R, Cullere X, Diaz C. Immunohistochemical localization of transforming growth factor alpha in the developing rat colon. Gastroenterology 1993; 104:789-795.
9. Oka Y, Orth DN. Human plasma epidermal growth factor/beta-urogastrone is associated with blood platelets. J Clin Invest 1983; 72:249-259.
10. Sarosiek J, Bilski J, Murty VL, Slomiany A, Slomiany BL. Role of salivary epidermal growth factor in the maintenance of physicochemical characteristics of oral and gastric mucosal mucus coat. Biochem Biophys Res Commun 1988; 152:1421-1427.
11. Maiden LT, Novak U, Burgess AW. Expression of transforming growth factor alpha messenger RNA in the normal and neoplastic gastro-intestinal tract. Int J Cancer 1989; 43:380-384.
12. Madtes DK, Raines EW, Sakariassen KS, Assoian RK, Sporn MB, Bell Gl, Ross R. Induction of transforming growth factor-alpha in activated human alveolar macrophages. Cell 1988; 53:285-293.
13. Lazar LM, Blum M. Regional distribution and developmental expression of epidermal growth factor and transforming growth factor-alpha mRNA in mouse brain by a quantitative nuclease protection assay. J Neurosci 1992; 12:1688-1697.
14. Yasui W, Ji ZQ, Kuniyasu H, Ayhan A, Yokozaki H, Ito H, Tahara E. Expression of transforming growth factor alpha in human tissues: immunohistochemical study and northern blot analysis. Virchows Arch A Pathol Anat Histopathol 1992;421:513-519.
15. Polk WH Jr, Dempsey PJ, Russell WE, Brown PI, Beauchamp RD, Barnard JA, Coffey RJ Jr. Increased production of transforming growth factor alpha following acute gastric injury. Gastroenterology 1992; 102:1467-1474.
16. Hoffmann P, Zeeh JM, Lakshmanan J, Wu VS, Procacinno F, Reinshagen M, et al. Increased expression of transforming growth factor alpha precursors in acute experimental colitis in rats. Gut 1997; 41:195-202.
17. Wong ST, Winchell LF, McCunG BK, Earp HS, Teixido J, Massague J, et al. The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 1989; 56:495-506.
18. Procaccino F, Reinshagen M, Hoffmann P, Zeeh JM, Lakshmanan J, McRoberts JA, et al. Protective effect of epidermal growth factor in an experimental model of colitis in rats. Gastroenterology 1994; 107:12-17.
19. Amagase H, Murakami T, Misaki M, Higashi Y, Ushijima M, Fuwa T, Yata N. Protective effect of human epidermal growth factor against the experimental gastric mucosal lesions in rats. Life Sci 1990; 47:1031-1036.
20. Egger B, Procaccino F, Lakshmanan J, Reinshagen M, Hoffman P, Patel A, et al. Mice lacking transforming growth factor alpha have an increased susceptibility to dextran sulfate-induced colitis. Gastroenterology 1997; 113:825-832.
21. Egger B, Carey HV, Procaccino F, Chai NN, Sandgren EP, Lakshmanan J, et al. Reduced susceptibility of mice overexpressing transforming growth factor alpha to dextran sodium sulphate induced colitis. Gut 1998; 43: 64-70.
22. Sinha A, Nightingale J, West KP, Berlanga-Acosta J, Playford RJ. Epidermal growth factor enemas with oral mesalamine for mild-to-moderate left-sided ulcerative colitis or proctitis. N Engl J Med 2003; 349: 350-357.
23. Wu SQ, Zhu WY, Yu JR. [Submaxillary gland epidermal growth factor accelerated healing of chronic gastric mucosal lesions in rats]. Sheng Li Xue Bao 1993; 45:575-580.
24. Dignass AU, Podolsky DK. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. Gastroenterology 1993; 105:1323-1332.
25. Hui WM, Chen BW, Kung AW, Cho CH, Luk CT, Lam SK. Effect of epidermal growth factor on gastric blood flow in rats: possible role in mucosal protection. Gastroenterology 1993; 104:1605-1610.
26. McLeay LM, Comeskey MA, Waters MJ. Effects of epidermal growth factor on gastrointestinal electromyographic activity of conscious sheep. J Endocrinol 1990; 124:109-115.
27. Kelly SM, Hunter JO. Epidermal growth factor stimulates synthesis and secretion of mucus glycoproteins in human gastric mucosa. Clin Sci (Lond) 1990; 79:425-427.
28. Rhodes JA, Tarn JP, Finke U, Saunders M, Bernanke J, Silen W, Murphy RA. Transforming growth factor alpha inhibits secretion of gastric acid. Proc Natl Acad Sci U S A 1 986; 83:3844-3846.
29. Al-Nafussi AI, Wright NA. The effect of epidermal growth factor (EGF) on cell proliferation of the gastrointestinal mucosa in rodents. Virchows Arch B Cell Pathol Incl Mol Pathol 1982; 40:63-69.
30. Gabrilove J, Mendelsohn J. Growth factors in human cancer. Curr Opin Oncol 1990; 2:163-170.
31. Mendelsohn J. The epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies. Semin Cancer Biol 1990; 1 : 339-344.
32. Hoffmann P, Dignass AU, Zeeh JM, Mazurkiewicz J, Holtmann G, Gerken G. Epithelial cell-derived components induce transforming growth factor-alpha mRNA expression and epithelial cell proliferation in vitro. Eur J Gastroenterol Hepatol 2001; 13:1333-1340.
33. Hoffmann P, Mazurkiewicz J, Holtmann G, Gerken G, Eysselein VE, Goebell H. Capsaicin-sensitive nerve fibres induce epithelial cell proliferation, inflammatory cell immigration and transforming growth factor-alpha expression in the rat colonic mucosa in vivo. Scand J Gastroenterol 2002; 37:414-422.
34. Chomczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162:156-159.
35. Derynck R. Transforming growth factor-alpha: structure and biological activities. J Cell Biochem 1986; 32:293-304.
36. Bone H, Bone M, Lindstrom C, Ohlsson K. Pancreatic secretory trypsin inhibitor in human Brunner's glands. J Gastroenterol 1995; 30:90-95.
37. Yoshikawa I. Effects of epidermal growth factor on alkaline secretion and mucus formation in rat duodenum exposed to luminal acid. Gastroenterol Jpn 1993; 28:496-504.
38. Flemstrom G, Kivilaakso E. Demonstration of a pH gradient at the luminal surface of rat duodenum in vivo and its dependence on mucosal alkaline secretion. Gastroenterology 1983; 84:787-794.
39. Hoffmann P, Zeeh JM, Lakshmanan J, Liu L, Cooray D, Barajas L, Eysselein VE. Transforming growth factor alpha-immunoreactivity in neural tissues of the rat stomach. Regul Pept 1997; 69:121-125.
40. Moore BA, Kim D, Vanner S, Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro. Am J Physiol Gastrointest Liver Physiol 2000; 279:G910-G917.
41. Kirkegaard P, Olsen PS, Poulsen SS, Nexo E. Exocrine secretion of epidermal growth factor from Brunner's glands. Stimulation by VIP and acetylcholine. Regul Pept 1983; 7:367-372.
42. Olsen PS, Poulsen SS, Kirkegaard P. Adrenergic effects on secretion of epidermal growth factor from Brunner's glands. Gut 1985; 26:920-927.
43. Lang IM, Tansy MF. Neural and hormonal control of Brunner's gland secretion. Life Sci 1982; 30:409-417.