Increased expression of transforming growth factor precursors in acute experimental colitis in rats

Gut

Volumn 41, Issue 2, 1997, Pages 195-202

  Hoffmann, P ^a,c   Zeeh, J M ^a   Lakshmanan, J ^a   Wu, V S ^b   Procaccino, F ^a   Reinshagen, M ^a   McRoberts, J A ^a   Eysselein, V E ^a  

^a HARBOR UCLA MEDICAL CENTER   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

Colitis; Epidermal growth factor (EGF); Precursor molecules; Rat; Transforming growth factor alpha (TGF )

Indexed keywords

ALCOHOL; EPIDERMAL GROWTH FACTOR; LIGAND; MESSENGER RNA; PROTEIN PRECURSOR; RIBONUCLEASE; TRANSFORMING GROWTH FACTOR ALPHA; TRINITROBENZENESULFONIC ACID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COLITIS; COLON MUCOSA; GENE EXPRESSION; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; PROTEIN PROCESSING; RAT;

EID: 0030869614     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.41.2.195     Document Type: Article

References (38)

1. Carpenter G, Cohen S. Epidermal growth factor. Ann Rev Biochem 1979; 48: 193-216.
2. Higashiyama S, Abraham JA, Miller J, Fiddes JC, Klagsbrun M. A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 1991; 251: 936-9.
3. Shoyab M, Plowman GD, McDonald VL, Bradley JG, Todaro GJ. Structure and function of human amphiregulin: a member of the epidermal growth factor family. Science 1989; 243: 1074-6.
4. DeLarco JE, Todaro GJ. Growth factors from murine sarcoma virus-transformed cells. Proc Natl Acad Sci USA 1978; 75: 4001-5.
5. Cartlidge SA, Elder JB. Transforming growth factor alpha and epidermal growth factor levels in normal human gastrointestinal mucosa. Br J Cancer 1989; 60: 657 60.
6. Miettinen PJ, Perheentupa J, Otonkoski T, Lahteenmaki A, Panula P. EGF- and TGF-alpha-like peptides in human fetal gut. Pediatr Res 1989; 26: 25-30.
7. Schaudies RP, Grimes J, Davis D, Rao RK, Koldovsky O. EGF content in the gastrointestinal tract of rats: effect of age and fasting feeding. Am J Physiol 1989; 256: G856-61.
8. Perez-Tomas R, Cullere X, Diaz C. Immunohistochemical localization of transforming growth factor alpha in the developing rat colon. Gastroenterology 1993; 104: 789-95.
9. Marquardt H, Hunkapiller MW, Hood LE, Todaro GJ. Rat transforming growth factor type I : structure and relation to epidermal growth factor. Science 1984; 223: 1079 82.
10. Mroczkowski B, Reich M, Chen K, Bell GI, Cohen S. Recombinant human epidermal growth factor precursor is a glycosilated membrane protein with biological activity. Mol Cell Biol 1989; 9: 2771-8.
11. Bringman TS, Lindquist PB, Derynck R. Different transforming growth factor alpha species are derived from a glycosylated and palmoylated transmembrane precursor. Cell 1987; 48: 429-40.
12. Linsley PS, Hargraves WR, Twardzik DR, Todaro GJ. Detection of larger polypeptides structurally and functionally related to type I transforming growth factor. Proc Natl Acad Sci USA 1985; 82: 356-60.
13. Teixido J, Gilmore R, Lee DC, Massague J. Integral membrane glycoprotein properties of prohormone pro-transforming growth factor alpha. Nature 1987; 326: 883-5.
14. Bosenberg MW, Pandiella A, Massaguë J. The cytoplasmic carboxy-terminal amino acid specifies cleavage of membrane TGF alpha into soluble growth factor. Cell 1992; 71: 1157-65.
15. Wong ST, Winchell LF, McCune BK, Earp HS, Teixido J, Massague J, et al. The TGF-alpha precursor expressed on the cell surface binds to the EGF receptor on adjacent cells, leading to signal transduction. Cell 1989; 56: 495-506.
16. Al-Nafussi AI, Wright NA. The effect of epidermal growth factor (EGF) on cell proliferation of the gastrointestinal mucosa in rodents. Virchows Arch B Cell Pathol 1982; 40: 63-9.
17. Dignass AU, Podolsky DK. Cytokine modulation of intestinal epithelial cell restitution: central role of transforming growth factor beta. Gastroenterology 1993; 105: 1323-32.
18. Hui WM, Chen BW, Kung ACX, Cho CH, Luk CT, Lam SK. Effect of epidermal growth factor on gastric blood flow in rats: possible role in mucosal protection. Gastroenterology 1993; 104: 1605-10.
19. McLeay LM, Comeskey MA, Waters MJ. Effects of epidermal growth factor on gastrointestinal electromyographic activity of conscious sheep. J Endocrinol 1990; 124: 109-15.
20. Kelly SM, Hunter O. Epidermal growth factor stimulates synthesis and secretion of mucus glycoproteins in human gastric mucosa. Clin Sci 1990; 79: 425-7.
21. Rhodes JA, Tam JP, Finke M, Saunders J, Bernanke J, Silen W, et al. Transforming growth factor alpha inhibits secretion of gastric acid. Proc Natl Acad Sci USA 1986; 83: 3844-6.
22. Wright NA, Pike C, Elia G. Induction of a novel epidermal growth factor-secreting cell lineage by mucosal ulceration in human gastrointestinal stem cells. Nature 1990; 343: 82-5.
23. Procaccino F, Reinshagen M, Hoffmann P, Zeeh JM, Lakshmanan J, McRoberts JA, et al. Protective effect of epidermal growth factor in an experimental model of colitis in rats. Gastroenterology 1994; 107: 12-17.
24. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidse activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344-50.
25. Lee DC, Rose TM, Webb NR, Todaro GJ. Cloning and sequencing of a cDNA tor rat transforming growth factor alpha. Nature 1985; 313: 489 91.
26. Saggi SJ, Safirstein R, Price PM. Cloning and sequencing of the rat preproepidermal growth factor cDNA: comparison with mouse and human sequences. DNA Cell Biol 1992; 11: 481 7.
27. Chromczynski P, Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal Biochem 1987; 162: 156 9.
28. Zanconato S, Moromisato DY, Moromisato MY, Woods J, Brasel JA, Leroith D, et al. Effect of training and growth hormone suppression on insulin-like growth factor I mRNA in young rats. J Appl Physiol 1944; 76: 2204 9.
29. Zamboni L, DeMartino C. Buffered picric-acid formaldehyde: a new rapid fixative for electron microscopy [abstract]. J Cell Biol 1967; 35: 148A.
30. Liu L, Barajas L. The rat renal nerves during development. Anat Embryol 1993; 188: 345 61.
31. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680 5.
32. Campbell ZX, Yamada T. Effect of omeprazole on gene expression in gastric parietal cells. Am J Physiol 1991; 260: G434 9.
33. Eysselein VE, Procaccino F, Reinshagen M, Hoffmann P, Patel A, Reuben W, et al. Mice deficient in transforming growth factor-alpha (WA-I) are highly susceptible to dextran sulfate colitis [abstract], Gastroenterology 1996; 108: A906.
34. Polk WH Jr, Dempsey PJ, Russell WE, Brown PI, Beauchamp RD, Barnard JA, Coffey RJ Jr. Increased production of transforming growth factor alpha following acute gastric injury. Gastroenterology 1992; 102: 1467 74.
35. Alison MR, Chinery R, Poulsom R, Ashwood P, Longcroft JM, Wright NA. Experimental ulceration leads to sequential expression of spasmolytic polypeptide, intestinal trefoil factor, epidermal growth factor and transforming growth factor alpha mRNAs in rat stomach. J Pathol 1995; 175: 405 14.
36. Mitchell MD. Epidermal growth factor actions on arachidonic acid metabolism in human amnion cells. Biochim Biophys Acta 1987; 928: 240 2.
37. Heck DE, Laskin DL, Gardner CR, Laskin JD. Epidermal growth factor suppresses nitric oxide and hydrogen peroxide production by keratinocytes. J Biol Chem 1992; 267: 21277 80.
38. Miettinen PJ. Transforming growth factor-alpha and epidermal growth factor expression in human fetal gastrointestinal tract. Pediatr Res 1993; 33: 481 6.