Characterisation of chitosan-coated vesicles encapsulating DNA suitable for gene delivery

Journal of Pharmaceutical Sciences

Volumn 97, Issue 9, 2008, Pages 3981-3997

  Kudsiova, L ^a   Arafiena, C ^a   Lawrence, M J ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Chitosan coated vesicles; Gene delivery

Indexed keywords

CHITOSAN; DIMYRISTOYLPHOSPHATIDYLCHOLINE; DIPALMITOYLPHOSPHATIDYLCHOLINE; DISTEAROYLPHOSPHATIDYLCHOLINE; DNA; LIPID; WATER;

ARTICLE; CIRCULAR DICHROISM; CONCENTRATION (PARAMETERS); CONFORMATION; ENCAPSULATION; GENE TARGETING; LIPID BILAYER; MOLECULAR WEIGHT; NEUTRON SCATTERING; THICKNESS; ULTRAVIOLET SPECTROSCOPY; ZETA POTENTIAL;

EID: 53549123567     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.21355     Document Type: Article

References (59)

1. Foster K, Foster H, Dickson JG. 2006. Gene therapy progress and prospects: Duchenne muscular dystrophy. Gene Ther 13:1677-1685.
2. Flotte TR. 1993. Prospects for virus-based gene-therapy for cystic-fibrosis. J Bioenerg Biomembr 25:37-42.
3. Salmons B, GunzburgWH. 1993. Targeting of retroviral vectors for gene-therapy. Hum Gene Ther 4: 129-141.
4. Morgan JR, Tompkins RG, Yarmush ML. 1993. Advances in recombinant retroviruses for gene delivery. Adv Drug Deliv Rev 12:143-158.
5. Behr JP. 1993. Synthetic gene-transfer vectors. Acc Chem Res 26:274-278.
6. Rolland AP. 1998. From genes to gene medicines: Recent advances in nonviral gene delivery. Crit Rev Ther Drug Carrier Syst 15:143-198.
7. Rao NM, Gopal V. 2006. Cell biological and biophysical aspects of lipid-mediated gene delivery. Biosci Rep 26:301-324.
8. Lv HT, Zhang SB, Wang B, Cui SH, Yan J. 2006. Toxicity of cationic lipids and cationic polymers in gene delivery. J Control Release 114:100-109.
9. Torchilin VP. 2005. Recent advances with liposomes as pharmaceutical carriers. Nat Rev Drug Discov 4:145-160.
10. Maruyama K, Okuizumi S, Ishida H, Yamauchi H, Kikuchi H, Iwatsuru M. 1994. Phosphatidyl poly-glycerols prolong liposome circulation in vivo. Int J Pharm 111:103-107.
11. Sammour OA. 2000. Encapsulation of plasmid DNA into dehydrated-rehydrated liposomes and its delivery to cells. Pharm Ind 62:56-59.
12. Jeffs LB, Palmer LR, Ambegiam EG, Giesbrecht C, Ewanick SMaclachlan I. 2005. A scalable, extrusion-free method for efficient liposomal encapsulation of plasmid DN. Pharm Res 22:362-372.
13. Park HM, Chung SY, Go EJ, Lee HJ. 2004. Immunoliposomes carrying plasmid DNA: Preparation and characterization. Arch Pharm Res 27:1263-1269.
14. Sandei G, Poggi P, Bonferoni MC, Rossi S, Ferrari F, Caramella C. 2006. Histological evaluation of buccal penetration enhancement properties of chitosan and trimethyl chitosan. J Pharm Pharmacol 58:1327-1336.
15. Smith J, Wood E, Dornish M. 2004. Effect of chitosan on epithelial cell tight junctions. Pharm Res 21:43-49.
16. Ranaldi G, Marigliano I, Vespignani I, Giuditta P, Sambuy Y. 2002. The effect of chitosan and other polycations on tight junction permeability in the human intestinal Caco-2 cell line. J Nutr Biochem 13:157-167.
17. Dodane V, Khan MA, Merwin JR. 1999. Effect of chitosan on epithelial permeability and structure. Int J Pharm 182:21-32.
18. Kotze AF, Lußen HL, de Boer AG, Verhoef JC, Junginger HE. 1998. Chitosan for enhanced intestinal permeability: Prospects for derivatives soluble in neutral and basic environments. Eur J Pharm Sci 7:145-151.
19. Kotze AF, de Leeuw BJ, Lußen HL, de Boer AG, Verhoef JC, Junginger HE. 1997. Chitosan for enhanced delivery of therapeutic peptides across intestinal epithelia: In vitro evaluation in Caco-2 cell monolayers. Int J Pharm 159:243-253.
20. Griesenbach U, Chonn A, Cassady R, Hannam V, Ackerley C, Post M, Transwell AK, Olek K, O'Brodovich H, Tsui LC. 1998. Comparison between intratracheal and intravenous administration of liposome-DNA complexes for cystic fibrosis lung gene therapy. Gene Ther 5:181-188.
21. Chu Q, Tousignant JD, Fang S, Jiang C, Eastman SJ, Chen LH, Cheng SH, Scheule RK. 1999. Binding and uptake of cationic lipid: pDNA Complexes by polarized airway epithelial cells. Gene Ther 10:25-36.
22. Henriksen I, Vagen SR, Sande SA, Smistad G, Karlsen J. 1997. Interaction between liposomes and chitosan II: Effect of selected parameters on aggregation and leakage. Int J Pharm 146:193-204.
23. Shi XY, Sun CM, Wu SK. 1999. Evaluation of in vitro stability of small unilamellar vesicles coated with collagen and chitosan. Polym Int 48: 212-216.
24. Filipovic-Grcic J, Skalko-Basnet N, Jalsenjak I. 2001. MucoaDResive chitosan-coated liposomes: Characteristics and stability. J Microencapsul 18: 3-12.
25. Bangham AD, Standish MM, Watkins JC. 1965. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 13:238-252.
26. Marsh D. 1990. Handbook of lipid bilayers. Boca Raton, FL, USA: CRC Press.
27. Kirby CJ, Gregoriadis G. 1984. Dehydration-rehydration vesicles - A simple method for high yield drug entrapment in liposomes. Biotechnology 2: 979-984.
28. Gregoriadis G, Saffie R, Hart SL. 1996. High yield incorporation of plasmid DNA within liposomes: Effect on DNA integrity and transfection efficiency. J Drug Target 3:469-475.
29. Henriksen I, Smistad G, Karlsen J. 1994. Interaction between liposomes and chitosan. Int J Pharm 101:227-236.
30. Muzzarelli RAA. 1998. Colorimetric determination of chitosan. Anal Biochem 260:255-257.
31. Kudsiova L. 2004. Novel gene delivery vectors produced from neutral lipids and chitosan. PhD Thesis, University of London.
32. Harvey RD, Heenan RK, Barlow DJ, Lawrence MJ. 2005. The effect of electrolyte on the morphology of vesicles composed of the dialkyl polyoxyethylene ether surfactant 2C(18)E(12). Chem Phys Lipids 133:27-36.
33. Heenan RK. 1989. RAL report 89-129, as subsequently revised. Didcot, UK: Rutherford Appleton Laboratory.
34. Arvinte T, Bui TTT, Dahab AA, Demeule B, Drake AF, Elhag D, King P. 2004. The multi-mode polarization modulation spectrometer: Part 1: simultaneous detection of absorption, turbidity, and optical activity. Anal Biochem 332:46-57.
35. Rand RP, Parsegian VA. 1985. Hydration forces between phospholipid-bilayers. Biochim Biophys Acta 988:351-376.
36. Wu C-M, Chen H-L, Liou W, Lin T-L, Jengi U-S. 2004. DNA-Induced aggregation of zwitterionic oligolamellar liposome. Biomacromolecules 5:2324-2328.
37. Deamer DW, Barchfled GL. 1982. Encapsulation of macromolecules by lipid vesicles under simulated prebiotic conditions. J Mol Evol 18:203-206.
38. Pupo E, Padrón A, Santana E, Sotolongo J, Quintana D, Duenas S, Duarte C, de la Rosa MC, Hardy E. 2005. Preparation of plasmid DNA-containing liposomes using a high-pressure homogenization-extrusion technique. J Control Release 104:379-396.
39. McManus JJ, Radicr JO, Dawson KA. 2003. Does calcium turn a zwitterionic lipid cationic? J Phys Chem B 107:9869-9875.
40. Callow P. 2000. Cationic lipid:DNA complexes - Their structure and interactions with model cell membranes. PhD Thesis, University of London.
41. Bokma JT, Johnson WC, Blok J. 1987. CD of the Lisalt of DNA in ethanol/water mixtures: Evidence for the B- to C-form transition in solution. Biopolymers 26:893-909.
42. Johnson WC. 1996. Determination of the conformation of nucleic acids by electronic CD. In: Fasman GD, editor. Circular dichroism and the conformational analysis of biomolecules. New York: Plenum Press.
43. Kikuchi H, Suzuki N, Ebihara K, Morita H, Ishii Y, Kikuchi A, Sugaya S, Serikawa T, Tanaka K. 1999. Gene delivery using liposome technology. J Control Release 62:269-277.
44. Bailey AL, Sullivan SM. 2000. Efficient encapsulation of DNA plasmids in small neutral liposomes induced by ethanol and calcium. Biochim Biophys Acta 1468:239-252.
45. Monnard PA, Oberholzer T, Luisi P. 1997. Entrapment of nucleic acids in liposomes. Biochim Biophys Acta 1329:39-50.
46. Perrie Y, Gregoriadis G. 2000. Liposome-entrapped plasmid DNA: Characterisation studies. Biochim Biophys Acta 1475:125-132.
47. Fillion P, Desjardins A, Sayasith K, Lagace J. 2001. Encapsulation of DNA in negatively charged liposomes and inhibition of bacterial gene expression with fluid liposome-encapsulated antisense oligonucleotide. Biochim Biophys Acta 1515:44-54.
48. Choon A, Cullis PR. 1998. Recent advances in liposome technologies and their applications for systemic gene delivery. Adv Drug Deliv Rev 30:73-83.
49. Radicr J, Koltover I, Salditt T, Safinya C. 1997. Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes. Science 275:810-814.
50. Budker VG, Slattum PM, Monahan SD, Wolff JA. 2002. Entrapment and condensation of DNA in neutral reverse micelles. Biophys J 82:1570-1579.
51. Rengel RG, Barisic K, Pavelic Z, Grubisic TZ, Cepelak I, Filipovic-Grcic J. 2002. High efficiency entrapment of superoxide dismutase into mucoa-DResive chitosan-coated liposomes. Eur J Pharm Sci 15:441-448.
52. Fang N, Chan V, Mao H, Leong K. 2001. Interactions of phospholipid bilayer with chitosan: Effect of molecular weight and pH. Biomacromolecules 2: 1161-1168.
53. Baumgart T, Offenhäusser A. 2003. Polysaccharide-supported planar bilayer lipid model membranes. Langmuir 19:1730-1737.
54. Bhutawala S, Drake AF. 2003. Mechanism of carbohydrate-dye interactions: Chitosan quantification in solution, MSc. Thesis, Pharmacy Department, King's College London.
55. Radeva T. 2002. Adsorption of polymer at colloid surfaces. In: Hubbard A, editor. Encyclopedia of surface and colloid science. New York: Marcel Dekker. pp 547-557.
56. Sepassi S, Goodwin DJ, Drake AF, Holland S, Leonard G, Martini L, Lawrence MJ. 2007. Effect of polymer molecular weight on the production of drug nanoparticles. J Pharm Sci 96:2655-2666.
57. Takeuchi H, Yamamoto H, Niwa T, Hino T, Kawashima Y. 1996. Eternal absorption of insulin in rats from mucoaDResive chitosan-coated liposomes. Pharm Res 13:896-901.
58. Geir J. 1993. Osmotic behaviour and permeability properties of liposomes. Chem Phys Lipids 64:187-196.
59. Kashchiev D, Exerowa D. 1984. Bilayer lipid membrane permeation and rupture due to hole formation. Biochim Biophys Acta 732:133-145.