Novel microtubule-interacting phenoxy pyridine and phenyl sulfanyl pyridine analogues for cancer therapy

Journal of Medicinal Chemistry

Volumn 51, Issue 19, 2008, Pages 5953-5957

  Anchoori, Ravi Kumar ^a   Kortenhorst, Madeleine Susanne Quirine ^a,b   Hidalgo, Manuel ^a   Sarkar, Taradas ^c   Hallur, Gurulingappa ^a   Bai, Ruoli ^c   Van Diest, Paul J ^b   Hamel, Ernest ^c   Khan, Saeed R ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEMECOLCINE; PACLITAXEL; PHENOXYPYRIDINE; PHENYLSULFANYLPYRIDINE DERIVATIVE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER THERAPY; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL PROLIFERATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MICROTUBULE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MICROTUBULES; MOLECULAR STRUCTURE; NEOPLASMS; PYRIDINES; SMALL MOLECULE LIBRARIES; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN;

EID: 53549122279     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm800203e     Document Type: Article

References (8)

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