Putative role of endothelial lipase in dialysis patients with hypoalbuminemia and inflammation

American Journal of Nephrology

Volumn 28, Issue 6, 2008, Pages 974-981

  Fujii, Hideki ^a   Fukuda, Akira ^a   Tanaka, Motoko ^b   Kojima, Yoko ^a   Ishida, Tatsuro ^a   Hirata, Ken Ichi ^a   Fukagawa, Masafumi ^a  

^a KOBE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Akebono Clinic   (Japan)

Author keywords

Cardiovascular events; Dialysis patients; Endothelial lipase; High density lipoprotein cholesterol; Hypoalbuminemia; Inflammation

Indexed keywords

BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLINESTERASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; SERUM ALBUMIN; TRIACYLGLYCEROL LIPASE; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AGED; ARTICLE; ATHEROGENESIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CORRELATION ANALYSIS; ENZYME ACTIVITY; FEMALE; FOLLOW UP; HEMODIALYSIS PATIENT; HUMAN; HYPOALBUMINEMIA; INFLAMMATION; KIDNEY FAILURE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; PATIENT CODING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; TRIACYLGLYCEROL LIPASE BLOOD LEVEL;

AGED; ATHEROSCLEROSIS; CHOLESTEROL, HDL; DISEASE PROGRESSION; FEMALE; HUMANS; HYPOALBUMINEMIA; INFLAMMATION; LIPASE; LIPIDS; MALE; MIDDLE AGED; RENAL DIALYSIS;

EID: 53549113307     PISSN: 02508095     EISSN: None     Source Type: Journal    
DOI: 10.1159/000144025     Document Type: Article

References (31)

1. Qureshi AR, Alvestrand A, Danielsson A, Divino-Filho JC, Gutierrez A, Lindholm B, Bergström J: Factors predicting malnutrition in hemodialysis patients: a cross-sectional study. Kidney Int 1998;53:773-782.
2. Cianciaruso B, Brunori G, Kopple JD, Traverso G, Panarello G, Enia G, Strippoli P, De Vecchi A, Querques M, Viglino G, et al: Cross-sectional comparison of malnutrition in continuous ambulatory peritoneal dialysis and hemodialysis patients. Am J Kidney Dis 1995;26:475-486.
3. Stenvinkel P, Heimburger O, Lindholm B, Kaysen GA, Bergstrom J: Are there two types of malnutrition in chronic renal failure? Evidence for relationships between malnutrition, inflammation and atherosclerosis (MIA syndrome). Nephrol Dial Transplant 2000;15:953-960.
4. Stenvinkel P, Lindholm B, Heimbürger M, Heimbürger O: Elevated serum levels of soluble adhesion molecules predict death in pre-dialysis patients: association with malnutrition, inflammation, and cardiovascular disease. Nephrol Dial Transplant 2000;15:1624-1630.
5. Wang AY, Wang M, Woo J, Lam CW, Lui SF, Li PK, Sanderson JE: Inflammation, residual kidney function, and cardiac hypertrophy are interrelated and combine adversely to enhance mortality and cardiovascular death risk of peritoneal dialysis patients. J Am Soc Nephrol 2004;15:2186-2194.
6. Panichi V, Migliori M, De Pietro S, Taccola D, Bianchi AM, Giovannini L, Norpoth M, Metelli MR, Cristofani R, Bertelli AA, Sbragia G, Tetta C, Palla R, Colombo R: C-reactive protein and interleukin-6 levels are related to renal function in predialytic chronic renal failure. Nephron 2002;91:594-600.
7. Zimmermann J, Herrlinger S, Pruy A, Metzger T, Wanner C: Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int 1999;55:648-658.
8. Qureshi AR, Alvestrand A, Divino-Filho JC, Gutierrez A, Heimbürger O, Lindholm B, Bergström J: Inflammation, malnutrition, and cardiac disease as predictors of mortality in hemodialysis patients. J Am Soc Nephrol 2002;13(suppl 1):S28-S36.
9. Nascimento MM, Pecoits-Filho R, Lindholm B, Riella MC, Stenvinkel P: Inflammation, malnutrition and atherosclerosis in end-stage renal disease: a global perspective. Blood Purif 2002;20:454-458.
10. Hirata K, Dichek HL, Cioffi JA, Choi SY, Leeper NJ, Quintana L, Kronmal GS, Cooper AD, Quertermous T: Cloning of a unique lipase from endothelial cells extends the lipase gene family. J Biol Chem 1999;274:14170-14175.
11. Jaye M, Lynch KJ, Krawiec J, Marchadier D, Maugeais C, Doan K, South V, Amin D, Perrone M, Rader DJ: A novel endothelial-derived lipase that modulates HDL metabolism. Nat Genet 1999;21:424-428.
12. Ishida T, Choi S, Kundu RK, Hirata K, Rubin EM, Cooper AD, Quertermous T: Endothelial lipase is a major determinant of HDL level. J Clin Invest 2003;111:347-355.
13. Hirata K, Ishida T, Matsushita H, Tsao PS, Quertermous T: Regulated expression of endothelial cell-derived lipase. Biochem Biophys Res Commun 2000;272:90-93.
14. Jin W, Sun GS, Marchadier D, Octtaviani E, Glick JM, Rader DJ: Endothelial cells secrete triglyceride lipase and phospholipase activities in response to cytokines as a result of endothelial lipase. Circ Res 2003;92:644-650.
15. Bradbury BD, Fissell RB, Albert JM, Anthony MS, Critchlow CW, Pisoni RL, et al: Predictors of early mortality among incident US hemodialysis patients in the Dialysis Outcomes and Practice Patterns Study (DOPPS). Clin J Am Soc Nephrol 2007;2:89-99.
16. Fliser D, Buchholz K, Haller H; EUropean Trial on Olmesartan and Pravastatin in Inflammation and Atherosclerosis (EUTOPIA) Investigators: Anti-inflammatory effects of angiotensin II subtype 1 receptor blockade in hypertensive patients with microinflammation. Circulation 2004;110:1103-1107.
17. Paradis ME, Badellino KO, Rader DJ, Deshaies Y, Couture P, Archer WR, Bergeron N, Lamarche B: Endothelial lipase is associated with inflammation in humans. J Lipid Res 2006;47:2808-2813.
18. Stenvinkel P, Heimbürger O, Paultre F, Diczfalusy U, Wang T, Berglund L, Jogestrand T: Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int 1999;55:1899-1911.
19. Pecoits-Filho R, Lindholm B, Stenvinkel P: The malnutrition, inflammation, and atherosclerosis (MIA) syndrome - the heart of the matter. Nephrol Dial Transplant 2002;17(suppl 11):28-31.
20. Barter P, Gotto AM, LaRosa JC, Maroni J, Szarek M, Grundy SM, Kastelein JJ, Bittner V, Fruchart JC; Treating to New Targets Investigators: HDL cholesterol, very low levels of LDL cholesterol, and cardiovascular events. N Engl J Med 2007;357:1301-1310.
21. Jin W, Millar JS, Broedl U, Glick JM, Rader DJ: Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo. J Clin Invest 2003;111:357-362.
22. Badellino KO, Wolfe ML, Reilly MP, Rader DJ: Endothelial lipase is increased in vivo by inflammation in humans. Circulation 2008;117:678-685.
23. Badellino KO, Wolfe ML, Reilly MP, Rader DJ: Endothelial lipase concentrations are increased in metabolic syndrome and associated with coronary atherosclerosis. PLoS Med 2006;3:245-252.
24. Menon V, Greene T, Wang X, Pereira AA, Marcovina SM, Beck GJ, Kusek JW, Collins AJ, Levey AS, Sarnak MJ: C-reactive protein and albumin as predictors of all-cause and cardiovascular mortality in chronic kidney disease. Kidney Int 2005;68:766-772.
25. Soriano S, González L, Martín-Malo A, Rodríguez M, Aljama P: C-reactive protein and low albumin are predictors of morbidity and cardiovascular events in chronic kidney disease 3-5 patients. Clin Nephrol 2007;67:352-357.
26. Hasham SN, Pillarisetti S: Vascular lipases, inflammation and atherosclerosis. Clin Chim Acta 2006;372:179-183.
27. Ishida T, Choi SY, Kundu RK, Spin J, Yamashita T, Hirata K, Kojima Y, Yokoyama M, Cooper AD, Quertermous T: Endothelial lipase modulates susceptibility to atherosclerosis in apolipoprotein-E-deficient mice. J Biol Chem 2004;279:45085-45092.
28. Azumi H, Hirata K, Ishida T, Kojima Y, Rikitake Y, Takeuchi S, Yokoyama M: Immunohistochemical localization of endothelial cell-derived lipase in atherosclerotic human coronary arteries. Cardiovasc Res 2003;58:647-654.
29. Bartels ED, Nielsen JE, Lindegaard ML, Hulten LM, Schroeder TV, Nielsen LB: Endothelial lipase is highly expressed in macrophages in advanced human atherosclerotic lesions. Atherosclerosis 2007;195:e42-e49.
30. Kojma Y, Hirata K, Ishida T, Shimokawa Y, Inoue N, Kawashima S, Quertermous T, Yokoyama M: Endothelial lipase modulates monocyte adhesion to the vessel wall. A potential role in inflammation. J Biol Chem 2004;279:54032- 54038.
31. Qiu G, Hill JS: Endothelial lipase enhances low density lipoprotein binding and cell association in THP-1 macrophages. Cardiovasc Res 2007;76:528-538.