Altered frontostriatal coupling in pre-manifest Huntington's disease: Effects of increasing cognitive load

European Journal of Neurology

Volumn 15, Issue 11, 2008, Pages 1180-1190

  Wolf, R C ^a   Sambataro, F ^b   Vasic, N ^a   Schonfeldt Lecuona C ^a   Ecker, D ^a   Landwehrmeyer, B ^a  

^a UNIVERSITY OF ULM   (Germany)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Cognition; Huntington's disease; Pre symptomatic; Prefrontal cortex; Psychophysiological interactions

Indexed keywords

ADULT; ARTICLE; CINGULATE GYRUS; CLINICAL ARTICLE; COGNITION; CONTROL GROUP; CONTROLLED STUDY; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HUNTINGTON CHOREA; MALE; PREFRONTAL CORTEX; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; PUTAMEN; RATING SCALE; STRIATE CORTEX; TASK PERFORMANCE; VERBAL MEMORY; WORKING MEMORY;

ADULT; AGE OF ONSET; BRAIN MAPPING; COGNITION; COGNITION DISORDERS; CORPUS STRIATUM; DISABILITY EVALUATION; DISEASE PROGRESSION; DNA MUTATIONAL ANALYSIS; EARLY DIAGNOSIS; FEMALE; GYRUS CINGULI; HUMANS; HUNTINGTON DISEASE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NERVE TISSUE PROTEINS; NEURAL PATHWAYS; NEUROPSYCHOLOGICAL TESTS; NUCLEAR PROTEINS; PREFRONTAL CORTEX; PUTAMEN;

EID: 53549112178     PISSN: 13515101     EISSN: 14681331     Source Type: Journal    
DOI: 10.1111/j.1468-1331.2008.02253.x     Document Type: Article

References (52)

1. Vonsattel JP, Myers RH, Stevens TJ. Neuropathological classification of Huntington's disease. Journal of Neuropathology and Experimental Neurology 1985 44 : 559 577.
2. Nopoulos P, Magnotta V, Mikos A, Paulson H, Andreasen NC, Paulsen JS. Morphology of the cerebral cortex in preclinical Huntington's disease. American Journal of Psychiatry 2007 164 : 1428 1429.
3. Rosas HD, Hevelone ND, Zaleta AK, Greve DN, Salat DH, Fischl B. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Neurology 2005 65 : 745 747.
4. Rosas HD, Feigin AS, Hersch SM. Using advances in neuroimaging to detect, understand, and monitor disease progression in Huntington's disease. NeuroRx 2004 1 : 263 272.
5. Lange KW, Sahakian BJ, Quinn NP, Marsden CD, Robbins TW. Comparison of executive and visuospatial memory function in Huntington's disease and dementia of Alzheimer type matched for degree of dementia. Journal of Neurology, Neurosurgery, and Psychiatry 1995 58 : 598 606.
6. Butters N, Sax D, Montgomery K, Tarlow S. Comparison of the neuropsychological deficits associated with early and advanced Huntington's disease. Archives of Neurology 1978 35 : 585 589.
7. Paulsen JS, Salmon DP, Monsch AU, Butters N, Swenson MR, Bondi MW. Discrimination of cortical from subcortical dementias on the basis of memory and problem-solving tests. Journal of Clinical Psychology 1995 51 : 48 58.
8. Snowden JS, Craufurd D, Thompson J, Neary D. Psychomotor, executive, and memory function in preclinical Huntington's disease. Journal of Clinical and Experimental Neuropsychology 2002 24 : 133 145.
9. Lemiere J, Decruyenaere M, Evers-Kiebooms G, Vandenbussche E, Dom R. Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation - a longitudinal follow-up study. Journal of Neurology 2004 251 : 935 942.
10. Hahn-Barma V, Deweer B, Durr A, et al. Are cognitive changes the first symptoms of Huntington's disease? A study of gene carriers. Journal of Neurology, Neurosurgery, and Psychiatry 1998 64 : 172 177.
11. Montoya A, Pelletier M, Menear M, Duplessis E, Richer F, Lepage M. Episodic memory impairment in Huntington's disease: a meta-analysis. Neuropsychologia 2006 44 : 1984 1994.
12. Solomon AC, Stout JC, Johnson SA, et al. Verbal episodic memory declines prior to diagnosis in Huntington's disease. Neuropsychologia 2007 45 : 1767 1776.
13. Nehl C, Ready RE, Hamilton J, Paulsen JS. Effects of depression on working memory in presymptomatic Huntington's disease. The Journal of Neuropsychiatry and Clinical Neurosciences 2001 13 : 342 346.
14. Lawrence AD, Weeks RA, Brooks DJ, et al. The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease. Brain 1998 121 : 1343 1355.
15. Feigin AS, Ghilardi MF, Huang C, et al. Preclinical Huntington's disease: compensatory brain responses during learning. Annals of Neurology 2006 59 : 53 59.
16. Reading SA, Dziorny AC, Peroutka LA, et al. Functional brain changes in presymptomatic Huntington's disease. Annals of Neurology 2004 55 : 879 883.
17. Zimbelman JL, Paulsen JS, Mikos AE, Reynolds NC, Hoffman RG, Rao SM. fMRI detection of early neural dysfunction in preclinical Huntington's disease. Journal of the International Neuropsychological Society 2007 13 : 758 769.
18. Paulsen JS, Zimbelman JL, Hinton SC, et al. fMRI biomarker of early neuronal dysfunction in presymptomatic Huntington's disease. American Journal of Neuroradiology 2004 25 : 1715 1721.
19. Paulsen JS, Magnotta VA, Mikos AE, et al. Brain structure in preclinical Huntington's disease. Biological Psychiatry 2006 59 : 57 63.
20. Wolf RC, Vasic N, Schönfeldt-Lecuona CL, Landwehrmeyer GB, Ecker D. Dorsolateral prefrontal cortex dysfunction in presymptomatic Huntington's disease: evidence from event-related fMRI. Brain 2007 130 : 2845 2857.
21. Alexander G, Delong M, Strick P. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Ann Rev Neurosci 1986 9 : 357 381.
22. Middleton FA, Strick PL. Basal ganglia and cerebellar loops: motor and cognitive circuits. Brain Research Reviews 2000 31 : 236 250.
23. Josephs O, Henson RN. Event-related functional magnetic resonance imaging: modelling, inference and optimization. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences 1999 354 : 1215 1228.
24. Wolf RC, Walter H. Evaluation of a novel event-related parametric fMRI paradigm investigating prefrontal function. Psychiatry Res Neuroimaging 2005 140 : 73 83.
25. Lewis SJ, Dove A, Robbins TW, Barker RA, Owen AM. Striatal contributions to working memory: a functional magnetic resonance imaging study in humans. European Journal of Neuroscience 2004 19 : 755 760.
26. Rypma B, Prabhakaran V, Desmond JE, Glover GH, Gabrieli JD. Load-dependent roles of frontal brain regions in the maintenance of working memory. NeuroImage 1999 9 : 216 226.
27. Friston KJ, Buechel C, Fink GR, Morris J, Rolls E, Dolan R. Psychophysiological and modulatory interactions in neuroimaging. NeuroImage 1997 6 : 218 229.
28. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia 1971 9 : 97 113.
29. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Archives of General Psychiatry 1961 4 : 561 571.
30. Langbehn DR, Brinkman RR, Falush D, Paulsen JS, Hayden MR, Group IHsDC. A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length. Clinical Genetics 2004 65 : 267 277.
31. Sternberg S. High-speed scanning in human memory. Science 1966 153 : 652 654.
32. Friston KJ, Holmes A, Worsley KJ, Poline JB, Frith CD, Frackowiak RSJ. Statistical parametric maps in functional imaging: a general linear approach. Human Brain Mapping 1995 2 : 189 210.
33. Friston KJ, Holmes AP, Poline JB, et al. Analysis of fMRI time-series revisited. Neuroimage 1995 2 : 45 53.
34. Brett M, Anton J-L, Valabregue R, Poline JB. Region of interest analysis using an SPM toolbox [abstract]. 8th International Conference on Functional Mapping of the Human Brain, June 2-6, 2002, Sendai, Japan. Available on CD-ROM in NeuroImage 2002 16.
35. Genovese CR, Lazar NA, Nichols T. Thresholding of statistical maps in functional neuroimaging using the false discovery rate. NeuroImage 2002 15 : 870 878.
36. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proceedings of the National Academy of Sciences USA 2003 100 : 9440 9445.
37. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. New York, NY : Thieme Medical Publishers, 1988.
38. Duvernoy HM. The Human Brain. Wien, NY : Springer, 1999.
39. Kuwert T, Lange HW, Boecker H, et al. Striatal glucose consumption in chorea-free subjects at risk of Huntington's disease. Journal of Neurology 1993 241 : 31 36.
40. Backman L, Robins-Wahlin TB, Lundin A, Ginovart N, Farde L. Cognitive deficits in Huntington's disease are predicted by dopaminergic PET markers and brain volumes. Brain 1997 120 : 2207 2217.
41. Kuwert T, Lange HW, Langen KJ, Herzog H, Aulich A, Feinendegen LE. Cortical and subcortical glucose consumption measured by PET in patients with Huntington's disease. Brain 1990 113 : 1405 1423.
42. Hasselbalch SG, Oberg G, Sorensen SA, et al. Reduced regional cerebral blood flow in Huntington's disease studied by SPECT. Journal of Neurology, Neurosurgery, and Psychiatry 1992 55 : 1018 1023.
43. Pavese N, Andrews TC, Brooks DJ, et al. Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. Brain 2003 126 : 1127 1135.
44. Feigin A, Tang C, Ma Y, et al. Thalamic metabolism and symptom onset in preclinical Huntington's disease. Brain 2007 130 : 2858 2867.
45. Harris GJ, Aylward E, Peyser CE, Pearlson GD, Brandt J, Roberts-Twillie JV. Single photon emission computed tomographic blood flow and magnetic resonance volume imaging of basal ganglia in Huntington's disease. Archives of Neurology 1996 53 : 316 324.
46. Wolf RC, Vasic N, Schönfeldt-Lecuona C, Ecker D, Landwehrmeyer GB. Cortical dysfunction in patients with Huntington's disease during working memory performance. Human Brain Mapping 2008 published in online January 2). doi :.
47. Pavese N, Gerhard A, Tai YF, Ho AK, Turkheimer F, Barker RA. Microglial activation correlates with severity in Huntington disease: a clinical and PET study. Neurology 2006 66 : 1638 1643.
48. Thiruvady DR, Georgiou-Karistianis N, Egan GF, et al. Functional connectivity of the prefrontal cortex in Huntington's disease. Journal of Neurology, Neurosurgery, and Psychiatry 2007 78 : 127 133.
49. Nopoulos P, Magnotta VA, Mikos A, Paulson H, Andreasen NC, Paulsen JS. Morphology of the cerebral cortex in preclinical Huntington's disease. American Journal of Psychiatry 2007 164 : 1428 1434.
50. Kipps CM, Duggins AJ, Mahant N, Gomes L, Ashburner J, McCusker EA. Progression of structural neuropathology in preclinical Huntington's disease: a tensor-based morphometry study. Journal of Neurology, Neurosurgery, and Psychiatry 2005 76 : 650 655.
51. Ashburner J, Friston KJ. Voxel-based morphometry - the methods. NeuroImage 2000 11 : 805 821.
52. Good CD, Johnsrude IS, Ashburner J, Henson RN, Friston KJ, Frackowiak RS. A voxel-based morphometric study of ageing in 465 normal adult human brains. NeuroImage 2001 14 : 21 36.