Intraventricular pre-treatment with rAAV-VEGF induces intracranial hypertension and aggravates ischemic injury at the early stage of transient focal cerebral ischemia in rats

Neurological Research

Volumn 30, Issue 8, 2008, Pages 868-875

  Li, Zhaojian ^a   Wang, Renzhi ^a   Li, Shifang ^b   Wei, Junji ^a   Zhang, Ziheng ^a   Li, Guilin ^a   Dou, Wanchen ^a   Wei, Yukui ^a   Feng, Ming ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b QINGDAO UNIVERSITY   (China)

Author keywords

Gene therapy; Intracranial pressure; Intraventricular approach; Stroke; Vascular endothelial growth factor

Indexed keywords

PARVOVIRUS VECTOR; RECOMBINANT VASCULOTROPIN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN EDEMA; BRAIN INFARCTION SIZE; BRAIN WATER; CONTROLLED STUDY; DISEASE EXACERBATION; DRUG EFFICACY; GENE OVEREXPRESSION; HEMISPHERE; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; LATERAL BRAIN VENTRICLE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROTOXICITY; NONHUMAN; PERFUSION WEIGHTED IMAGING; RAT; REPERFUSION INJURY; SCORING SYSTEM; TRANSIENT ISCHEMIC ATTACK; TREATMENT OUTCOME; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; WATER CONTENT;

ANIMALS; BODY WATER; BRAIN; BRAIN EDEMA; CEREBRAL INFARCTION; DEPENDOVIRUS; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNOHISTOCHEMISTRY; INFARCTION, MIDDLE CEREBRAL ARTERY; INJECTIONS, INTRAVENTRICULAR; INTRACRANIAL HYPERTENSION; INTRACRANIAL PRESSURE; ISCHEMIC ATTACK, TRANSIENT; MAGNETIC RESONANCE IMAGING; MALE; RATS; RATS, WISTAR; REPERFUSION INJURY; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTORS;

EID: 53549112176     PISSN: 01616412     EISSN: None     Source Type: Journal    
DOI: 10.1179/174313208X309720     Document Type: Article

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