-
1
-
-
0026537051
-
The origin of pattern and polarity in the Drosophila embryo
-
St Johnston D., and Nusslein-Volhard C. The origin of pattern and polarity in the Drosophila embryo. Cell 68 (1992) 201-219
-
(1992)
Cell
, vol.68
, pp. 201-219
-
-
St Johnston, D.1
Nusslein-Volhard, C.2
-
2
-
-
0842303319
-
Seeing is believing: the bicoid morphogen gradient matures
-
Ephrussi A., and St Johnston D. Seeing is believing: the bicoid morphogen gradient matures. Cell 116 (2004) 143-152
-
(2004)
Cell
, vol.116
, pp. 143-152
-
-
Ephrussi, A.1
St Johnston, D.2
-
3
-
-
0023679744
-
The Bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner
-
Driever W., and Nusslein-Volhard C. The Bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner. Cell 54 (1988) 95-104
-
(1988)
Cell
, vol.54
, pp. 95-104
-
-
Driever, W.1
Nusslein-Volhard, C.2
-
4
-
-
0024380401
-
The gradient morphogen Bicoid is a concentration-dependent transcriptional activator
-
Struhl G., Struhl K., and Macdonald P.M. The gradient morphogen Bicoid is a concentration-dependent transcriptional activator. Cell 57 (1989) 1259-2127
-
(1989)
Cell
, vol.57
, pp. 1259-2127
-
-
Struhl, G.1
Struhl, K.2
Macdonald, P.M.3
-
5
-
-
0023677769
-
A gradient of Bicoid protein in Drosophila embryos
-
Driever W., and Nusslein-Volhard C. A gradient of Bicoid protein in Drosophila embryos. Cell 54 (1988) 83-93
-
(1988)
Cell
, vol.54
, pp. 83-93
-
-
Driever, W.1
Nusslein-Volhard, C.2
-
6
-
-
29444460232
-
Diffusion and scaling during early embryonic pattern formation
-
The first direct experimental analysis of morphogen scaling across species.
-
Gregor T., Bialek W., de Ruyter van Steveninck R.R., Tank D.W., and Wieschaus E.F. Diffusion and scaling during early embryonic pattern formation. Proc Natl Acad Sci U S A 102 (2005) 18403-18407. The first direct experimental analysis of morphogen scaling across species.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 18403-18407
-
-
Gregor, T.1
Bialek, W.2
de Ruyter van Steveninck, R.R.3
Tank, D.W.4
Wieschaus, E.F.5
-
7
-
-
0014593403
-
Positional information and spatial pattern of cellular differentiation
-
Wolpert L. Positional information and spatial pattern of cellular differentiation. J Theor Biol 25 (1969) 1-47
-
(1969)
J Theor Biol
, vol.25
, pp. 1-47
-
-
Wolpert, L.1
-
8
-
-
0014968933
-
Diffusion in embryogenesis
-
Crick F.H. Diffusion in embryogenesis. Nature 225 (1972) 420-422
-
(1972)
Nature
, vol.225
, pp. 420-422
-
-
Crick, F.H.1
-
9
-
-
34447104600
-
Stability and nuclear dynamics of the Bicoid morphogen gradient
-
Direct analysis of the dynamics of the Bicoid morphogen and demonstration of the fact that this gradient is dissolved and reformed with every nuclear division.
-
Gregor T., Wieschaus E., McGregor A.P., Bialek W., and Tank D.W. Stability and nuclear dynamics of the Bicoid morphogen gradient. Cell 130 (2007) 141-153. Direct analysis of the dynamics of the Bicoid morphogen and demonstration of the fact that this gradient is dissolved and reformed with every nuclear division.
-
(2007)
Cell
, vol.130
, pp. 141-153
-
-
Gregor, T.1
Wieschaus, E.2
McGregor, A.P.3
Bialek, W.4
Tank, D.W.5
-
10
-
-
36549006909
-
Modeling the Bicoid gradient: diffusion and reversible nuclear trapping of a stable protein
-
Biophysical model that suggests that most of the properties of the Bicoid gradient, which has been traditionally thought to be formed by diffusion and degradation, can be explained using a model where Bicoid is a stable protein that is reversibly trapped by syncytial nuclei.
-
Coppey M., Berezhkovskii A.M., Kim Y., Boettiger A.N., and Shvartsman S.Y. Modeling the Bicoid gradient: diffusion and reversible nuclear trapping of a stable protein. Dev Biol 312 (2007) 623-630. Biophysical model that suggests that most of the properties of the Bicoid gradient, which has been traditionally thought to be formed by diffusion and degradation, can be explained using a model where Bicoid is a stable protein that is reversibly trapped by syncytial nuclei.
-
(2007)
Dev Biol
, vol.312
, pp. 623-630
-
-
Coppey, M.1
Berezhkovskii, A.M.2
Kim, Y.3
Boettiger, A.N.4
Shvartsman, S.Y.5
-
11
-
-
0020531221
-
Studies of nuclear and cytoplasmic behavior during the 5 mitotic-cycles that precede gastrulation in Drosophila embryogenesis
-
Foe V.E., and Alberts B.M. Studies of nuclear and cytoplasmic behavior during the 5 mitotic-cycles that precede gastrulation in Drosophila embryogenesis. J Cell Sci 61 (1983) 31-70
-
(1983)
J Cell Sci
, vol.61
, pp. 31-70
-
-
Foe, V.E.1
Alberts, B.M.2
-
12
-
-
0027850403
-
The torso pathway in Drosophila - a model system to study receptor tyrosine kinase signal-transduction
-
Lu X.Y., Perkins L.A., and Perrimon N. The torso pathway in Drosophila - a model system to study receptor tyrosine kinase signal-transduction. Development (1993) 47-56
-
(1993)
Development
, pp. 47-56
-
-
Lu, X.Y.1
Perkins, L.A.2
Perrimon, N.3
-
13
-
-
14644388169
-
Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development
-
Li W.X. Functions and mechanisms of receptor tyrosine kinase Torso signaling: lessons from Drosophila embryonic terminal development. Dev Dyn 232 (2005) 656-672
-
(2005)
Dev Dyn
, vol.232
, pp. 656-672
-
-
Li, W.X.1
-
14
-
-
0024848240
-
Localized surface-activity of Torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila
-
Casanova J., and Struhl G. Localized surface-activity of Torso, a receptor tyrosine kinase, specifies terminal body pattern in Drosophila. Genes Dev 3 (1989) 2025-2038
-
(1989)
Genes Dev
, vol.3
, pp. 2025-2038
-
-
Casanova, J.1
Struhl, G.2
-
15
-
-
0030062199
-
Variation in the number of activated torso receptors correlates with differential gene expression
-
Furriols M., Sprenger F., and Casanova J. Variation in the number of activated torso receptors correlates with differential gene expression. Development 122 (1996) 2313-2317
-
(1996)
Development
, vol.122
, pp. 2313-2317
-
-
Furriols, M.1
Sprenger, F.2
Casanova, J.3
-
16
-
-
0031455262
-
Different levels of Ras activity can specify distinct transcriptional and morphological consequences in early Drosophila embryos
-
Greenwood S., and Struhl G. Different levels of Ras activity can specify distinct transcriptional and morphological consequences in early Drosophila embryos. Development 124 (1997) 4879-4886
-
(1997)
Development
, vol.124
, pp. 4879-4886
-
-
Greenwood, S.1
Struhl, G.2
-
17
-
-
0343986271
-
Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning
-
Jimenez G., Guichet A., Ephrussi A., and Casanova J. Relief of gene repression by Torso RTK signaling: role of capicua in Drosophila terminal and dorsoventral patterning. Genes Dev 14 (2000) 224-231
-
(2000)
Genes Dev
, vol.14
, pp. 224-231
-
-
Jimenez, G.1
Guichet, A.2
Ephrussi, A.3
Casanova, J.4
-
18
-
-
33846946102
-
A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling
-
Astigarraga S., Grossman R., Diaz-Delfin J., Caelles C., Paroush Z., and Jimenez G. A MAPK docking site is critical for downregulation of Capicua by Torso and EGFR RTK signaling. EMBO J 26 (2007) 668-677
-
(2007)
EMBO J
, vol.26
, pp. 668-677
-
-
Astigarraga, S.1
Grossman, R.2
Diaz-Delfin, J.3
Caelles, C.4
Paroush, Z.5
Jimenez, G.6
-
19
-
-
42149130936
-
Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis
-
Cinnamon E., Helman A., Ben-Haroush S.R., Orian A., Jiménez G., and Paroush Z. Multiple RTK pathways downregulate Groucho-mediated repression in Drosophila embryogenesis. Development 135 (2008) 829-837
-
(2008)
Development
, vol.135
, pp. 829-837
-
-
Cinnamon, E.1
Helman, A.2
Ben-Haroush, S.R.3
Orian, A.4
Jiménez, G.5
Paroush, Z.6
-
20
-
-
0026649985
-
Bicoid and the terminal system activate tailless expression in the early Drosophila embryo
-
Pignoni F., Steingrimsson E., and Lengyel J.A. Bicoid and the terminal system activate tailless expression in the early Drosophila embryo. Development 115 (1992) 239-251
-
(1992)
Development
, vol.115
, pp. 239-251
-
-
Pignoni, F.1
Steingrimsson, E.2
Lengyel, J.A.3
-
21
-
-
0025999610
-
Control and function of terminal gap gene activity in the posterior pole region of the Drosophila embryo
-
Bronner G., and Jackle H. Control and function of terminal gap gene activity in the posterior pole region of the Drosophila embryo. Mech Dev 35 (1991) 205-211
-
(1991)
Mech Dev
, vol.35
, pp. 205-211
-
-
Bronner, G.1
Jackle, H.2
-
22
-
-
0025281842
-
The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid-receptor superfamily
-
Pignoni F., Baldarelli R.M., Steingrimsson E., Diaz R.J., Patapoutian A., Merriam J.R., and Lengyel J.A. The Drosophila gene tailless is expressed at the embryonic termini and is a member of the steroid-receptor superfamily. Cell 62 (1990) 151-163
-
(1990)
Cell
, vol.62
, pp. 151-163
-
-
Pignoni, F.1
Baldarelli, R.M.2
Steingrimsson, E.3
Diaz, R.J.4
Patapoutian, A.5
Merriam, J.R.6
Lengyel, J.A.7
-
23
-
-
0025361358
-
2 gap genes mediate maternal terminal pattern information in Drosophila
-
Weigel D., Jurgens G., Klingler M., and Jackle H. 2 gap genes mediate maternal terminal pattern information in Drosophila. Science 248 (1990) 495-498
-
(1990)
Science
, vol.248
, pp. 495-498
-
-
Weigel, D.1
Jurgens, G.2
Klingler, M.3
Jackle, H.4
-
24
-
-
0037881950
-
In and out of Torso RTK signalling
-
Furriols M., and Casanova J. In and out of Torso RTK signalling. EMBO J 22 (2003) 1947-1952
-
(2003)
EMBO J
, vol.22
, pp. 1947-1952
-
-
Furriols, M.1
Casanova, J.2
-
25
-
-
0026458721
-
Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg
-
Sprenger F., and Nüsslein-Volhard C. Torso receptor activity is regulated by a diffusible ligand produced at the extracellular terminal regions of the Drosophila egg. Cell 71 (1992) 987-1001
-
(1992)
Cell
, vol.71
, pp. 987-1001
-
-
Sprenger, F.1
Nüsslein-Volhard, C.2
-
26
-
-
45449115714
-
Nuclear trapping shapes the terminal patterning gradient in the Drosophila embryo
-
First quantitative analysis of the terminal patterning system and demonstration that the spatial gradient of MAPK activation is dynamic and controlled by the number of syncytial nuclei.
-
Coppey M., Boettiger A.N., Berezhkovskii A.M., and Shvartsman SY:. Nuclear trapping shapes the terminal patterning gradient in the Drosophila embryo. Current Biology 18 12 (2008) 915-919. First quantitative analysis of the terminal patterning system and demonstration that the spatial gradient of MAPK activation is dynamic and controlled by the number of syncytial nuclei.
-
(2008)
Current Biology
, vol.18
, Issue.12
, pp. 915-919
-
-
Coppey, M.1
Boettiger, A.N.2
Berezhkovskii, A.M.3
Shvartsman, S.Y.4
-
28
-
-
33646852421
-
Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes
-
Direct analysis of dynamics of multiple components of the MAPK pathway in cultured cells.
-
Fujioka A., Terai K., Itoh R.E., Aoki K., Nakamura T., Kuroda S., Nishida E., and Matsuda M. Dynamics of the Ras/ERK MAPK cascade as monitored by fluorescent probes. J Biol Chem 281 (2006) 8917-8926. Direct analysis of dynamics of multiple components of the MAPK pathway in cultured cells.
-
(2006)
J Biol Chem
, vol.281
, pp. 8917-8926
-
-
Fujioka, A.1
Terai, K.2
Itoh, R.E.3
Aoki, K.4
Nakamura, T.5
Kuroda, S.6
Nishida, E.7
Matsuda, M.8
-
29
-
-
33845886924
-
Dynamic regulation of ERK2 nuclear translocation and mobility in living cells
-
Costa M., Marchi M., Cardarelli F., Roy A., Beltram F., Maffei L., and Ratto G.M. Dynamic regulation of ERK2 nuclear translocation and mobility in living cells. J Cell Sci 119 (2006) 4952-4963
-
(2006)
J Cell Sci
, vol.119
, pp. 4952-4963
-
-
Costa, M.1
Marchi, M.2
Cardarelli, F.3
Roy, A.4
Beltram, F.5
Maffei, L.6
Ratto, G.M.7
-
30
-
-
33751290690
-
Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases
-
Karlsson M., Mandl M., and Keyse S.M. Spatio-temporal regulation of mitogen-activated protein kinase (MAPK) signalling by protein phosphatases. Biochem Soc Trans 34 (2006) 842-845
-
(2006)
Biochem Soc Trans
, vol.34
, pp. 842-845
-
-
Karlsson, M.1
Mandl, M.2
Keyse, S.M.3
-
31
-
-
0027477909
-
The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila
-
Casanova J., and Struhl G. The torso receptor localizes as well as transduces the spatial signal specifying terminal body pattern in Drosophila. Nature 362 (1993) 152-155
-
(1993)
Nature
, vol.362
, pp. 152-155
-
-
Casanova, J.1
Struhl, G.2
-
32
-
-
0024464666
-
Mitotic domains reveal early commitment of cells in Drosophila embryos
-
Foe V.E. Mitotic domains reveal early commitment of cells in Drosophila embryos. Development 107 (1989) 1-22
-
(1989)
Development
, vol.107
, pp. 1-22
-
-
Foe, V.E.1
-
33
-
-
0344884994
-
Mitotic domains partition fly embryos, reflecting early cell biological consequences of determination in progress
-
Foe V.E., and Odell G.M. Mitotic domains partition fly embryos, reflecting early cell biological consequences of determination in progress. Am Zool 29 (1989) 617-652
-
(1989)
Am Zool
, vol.29
, pp. 617-652
-
-
Foe, V.E.1
Odell, G.M.2
-
34
-
-
27644547453
-
Bicoid determines sharp and precise target gene expression in the Drosophila embryo
-
Based on experiments with transcriptional reporters of Bicoid activity, it is shown that the Bicoid gradient must be precise.
-
Crauk O., and Dostatni N. Bicoid determines sharp and precise target gene expression in the Drosophila embryo. Curr Biol 15 (2005) 1888-1898. Based on experiments with transcriptional reporters of Bicoid activity, it is shown that the Bicoid gradient must be precise.
-
(2005)
Curr Biol
, vol.15
, pp. 1888-1898
-
-
Crauk, O.1
Dostatni, N.2
-
35
-
-
33846359035
-
Known maternal gradients are not sufficient for the establishment of gap domains in Drosophila melanogaster
-
Jaeger J., Sharp D.H., and Reinitz J. Known maternal gradients are not sufficient for the establishment of gap domains in Drosophila melanogaster. Mech Dev 124 (2007) 108-128
-
(2007)
Mech Dev
, vol.124
, pp. 108-128
-
-
Jaeger, J.1
Sharp, D.H.2
Reinitz, J.3
-
36
-
-
33846958053
-
Pre-steady-state decoding of the bicoid morphogen gradient
-
Experimental and computational study that analyzes the nonsteady readout of the Bicoid morphogen.
-
Bergmann S., Sandler O., Sberro H., Shnider S., Schejter E., Shilo B.Z., and Barkai N. Pre-steady-state decoding of the bicoid morphogen gradient. PLoS Biol 5 (2007) 232-242. Experimental and computational study that analyzes the nonsteady readout of the Bicoid morphogen.
-
(2007)
PLoS Biol
, vol.5
, pp. 232-242
-
-
Bergmann, S.1
Sandler, O.2
Sberro, H.3
Shnider, S.4
Schejter, E.5
Shilo, B.Z.6
Barkai, N.7
-
37
-
-
38349000721
-
Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis
-
Direct analysis of the dynamics of Dorsal levels in syncytial nuclei shows that the gradient of nuclear Dorsal is strongly affected by the dynamics of nuclear divisions.
-
DeLotto R., DeLotto Y., Steward R., and Lippincott-Schwartz J. Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis. Development 134 (2007) 4233-4241. Direct analysis of the dynamics of Dorsal levels in syncytial nuclei shows that the gradient of nuclear Dorsal is strongly affected by the dynamics of nuclear divisions.
-
(2007)
Development
, vol.134
, pp. 4233-4241
-
-
DeLotto, R.1
DeLotto, Y.2
Steward, R.3
Lippincott-Schwartz, J.4
-
38
-
-
33750470416
-
Nuclear factor-kappa B pathways in Drosophila
-
Minakhina S., and Steward R. Nuclear factor-kappa B pathways in Drosophila. Oncogene 25 (2006) 6749-6757
-
(2006)
Oncogene
, vol.25
, pp. 6749-6757
-
-
Minakhina, S.1
Steward, R.2
-
39
-
-
0037044575
-
The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation
-
Mechanistic modeling of the NF-κB pathway.
-
Hoffmann A., Levchenko A., Scott M.L., and Baltimore D. The IkappaB-NF-kappaB signaling module: temporal control and selective gene activation. Science 298 (2002) 1241-1245. Mechanistic modeling of the NF-κB pathway.
-
(2002)
Science
, vol.298
, pp. 1241-1245
-
-
Hoffmann, A.1
Levchenko, A.2
Scott, M.L.3
Baltimore, D.4
|