Brain function in physiologically, pharmacologically, and pathologically altered states of consciousness

International Anesthesiology Clinics

Volumn 46, Issue 3, 2008, Pages 131-146

  Boveroux, Pierre ^a   Bonhomme, Vincent ^a   Boly, Mélanie ^a   Vanhaudenhuyse, Audrey ^a   Maquet, Pierre ^a   Laureys, Steven ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; AWARENESS; BRAIN FUNCTION; BRAIN METABOLISM; BRAIN REGION; COMA; CONSCIOUSNESS; GENERAL ANESTHESIA; HUMAN; NERVE CELL NETWORK; NEUROIMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; UNCONSCIOUSNESS; BRAIN; CONSCIOUSNESS DISORDER; MENTAL FUNCTION; METABOLISM; PATHOPHYSIOLOGY; PERSISTENT VEGETATIVE STATE; PHYSIOLOGY; REVIEW; SLEEP;

ANESTHESIA, GENERAL; BRAIN; COMA; CONSCIOUSNESS; CONSCIOUSNESS DISORDERS; HUMANS; MENTAL PROCESSES; PERSISTENT VEGETATIVE STATE; SLEEP;

EID: 53449102259     PISSN: 00205907     EISSN: None     Source Type: Journal    
DOI: 10.1097/AIA.0b013e318181a8b3     Document Type: Article

References (78)

1. Laureys S. The neural correlate of (un) awareness: lessons from the vegetative state. Trends Cogn Sci. 2005;9:556-559.
2. Zeman A. Consciousness. Brain. 2001;124:1263-1289.
3. Steriade M. Sleep, epilepsy and thalamic reticular inhibitory neurons. Trends Neurosci. 2005;28:317-324.
4. Baars BJ, Ramsoy TZ, Laureys S. Brain, conscious experience and the observing self. Trends Neurosci. 2003;26:671-675.
5. Dehaene S, Changeux JP, Naccache L, et al. Conscious, preconscious, and subliminal processing: a testable taxonomy. Trends Cogn Sci. 2006;10:204-211.
6. Gusnard DA, Akbudak E, Shulman GL, et al. Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci USA. 2001;98:4259-4264.
7. Fox MD, Snyder AZ, Vincent JL, et al. The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA. 2005;102: 9673-9678.
8. Greicius MD, Krasnow B, Reiss AL, et al. Functional connectivity in the resting brain: a network analysis of the default mode hypothesis. Proc Natl Acad Sci USA. 2003;100: 253-258.
9. Cavanna AE, Trimble MR. The precuneus: a review of its functional anatomy and behavioural correlates. Brain. 2006;129:564-583.
10. Boly M, Phillips C, Balteau E, et al. Consciousness and cerebral baseline activity fluctuations. Hum Brain Mapp. 2008;29:868-874.
11. Boly M, Balteau E, Schnakers C, et al. Baseline brain activity fluctuations predict somatosensory perception in humans. Proc Natl Acad Sci USA. 2007;104: 12187-12192.
12. Bonhomme V, Maquet P, Phillips C, et al. The effect of clonidine infusion on distribution of regional cerebral blood flow in volunteers. Anesth Analg. 2008;106: 899-909.
13. Laureys S. Eyes open, brain shut. Sci Am. 2007;296:84-89.
14. Majerus S, Gill-Thwaites H, Andrews K, et al. Behavioral evaluation of consciousness in severe brain damage. Prog Brain Res. 2005;150:397-413.
15. Maquet P, Degueldre C, Delfiore G, et al. Functional neuroanatomy of human slow wave sleep. J Neurosci. 1997;17:2807-2812.
16. Buchsbaum MS, Gillin JC, Wu J, et al. Regional cerebral glucose metabolic rate in human sleep assessed by positron emission tomography. Life Sci. 1989;45:1349-1356.
17. Maquet P. Functional neuroimaging of normal human sleep by positron emission tomography. J Sleep Res. 2000;9:207-231.
18. Alkire MT, Haier RJ, Barker SJ, et al. Cerebral metabolism during propofol anesthesia in humans studied with positron emission tomography. Anesthesiology. 1995;82:393-403.
19. Alkire MT, et al. Functional brain imaging during anesthesia in humans: effects of halothane on global and regional cerebral glucose metabolism. Anesthesiology. 1999; 90:701-709.
20. Alkire MT, Haier RJ, Shah NK, et al. Positron emission tomography study of regional cerebral metabolism in humans during isoflurane anesthesia. Anesthesiology. 1997; 86:549-557.
21. Schaafsma A, de Jong BM, Bams JL, et al. Cerebral perfusion and metabolism in resuscitated patients with severe post-hypoxic encephalopathy. J Neurol Sci. 2003; 210:23-30.
22. Tommasino C, Grana C, Lucignani G, et al. Regional cerebral metabolism of glucose in comatose and vegetative state patients. J Neurosurg Anesthesiol. 1995;7:109-116.
23. Hattori N, Huang SC, Wu HM, et al. Correlation of regional metabolic rates of glucose with glasgow coma scale after traumatic brain injury. J Nucl Med. 2003; 44:1709-1716.
24. Bergsneider M, Hovda DA, McArthur DL, et al. Metabolic recovery following human traumatic brain injury based on FDG-PET: time course and relationship to neurological disability. J Head Trauma Rehabil. 2001;16:135-148.
25. Levy DE, Sidtis JJ, Rottenberg DA, et al. Differences in cerebral blood flow and glucose utilization in vegetative versus locked-in patients. Ann Neurol. 1987;22: 673-682.
26. De Volder AG, Goffinet AM, Bol A, et al. Brain glucose metabolism in postanoxic syndrome. Positron emission tomographic study. Arch Neurol. 1990;47:197-204.
27. Rudolf J, Ghaemi M, Haupt WF, et al. Cerebral glucose metabolism in acute and persistent vegetative state. J Neurosurg Anesthesiol. 1999;11:17-24.
28. Laureys S, Goldman S, Phillips C, et al. Impaired effective cortical connectivity in vegetative state. Neuroimage. 1999;9:377-382.
29. Laureys S, Lemaire C, Maquet P, et al. Cerebral metabolism during vegetative state and after recovery to consciousness. J Neurol Neurosurg Psychiatry. 1999; 67:121.
30. Schiff ND, Ribary U, Moreno DR, et al. Residual cerebral activity and behavioural fragments can remain in the persistently vegetative brain. Brain. 2002;125: 1210-1234.
31. Braun AR, Balkin TJ, Wesenten NJ, et al. Regional cerebral blood flow throughout the sleep-wake cycle. An H2(15)O PET study. Brain. 1997;120:1173-1197.
32. Maquet P, Peters J, Aerts J, et al. Functional neuroanatomy of human rapid-eye-movement sleep and dreaming. Nature. 1996;383:163-166.
33. Nofzinger EA, Buysse DJ, Miewald JM, et al. Human regional cerebral glucose metabolism during non-rapid eye movement sleep in relation to waking. Brain. 2002;125:1105-1115.
34. Raichle ME, Mintun MA. Brain work and brain imaging. Annu Rev Neurosci. 2006; 29:449-476.
35. Fiset P, Paus T, Daloze T, et al. Brain mechanisms of propofol-induced loss of consciousness in humans: a positron emission tomographic study. J Neurosci. 1999; 19:5506-5513.
36. Kaisti KK, Langsjo JW, Aalto S, et al. Effects of sevoflurane, propofol, and adjunct nitrous oxide on regional cerebral blood flow, oxygen consumption, and blood volume in humans. Anesthesiology. 2003;99:603-613.
37. Laureys S, Owen AM, Schiff ND. Brain function in coma, vegetative state, and related disorders. Lancet Neurol. 2004;3:537-546.
38. Salek-Haddadi A, Lemieux L, Merschhemke M, et al. Functional magnetic resonance imaging of human absence seizures. Ann Neurol. 2003;53:663-667.
39. Aghakhani Y, Bagshaw AP, Benar CG, et al. fMRI activation during spike and wave discharges in idiopathic generalized epilepsy. Brain. 2004;127:1127-1144.
40. Laufs H, Lengler U, Hamandi K, et al. Linking generalized spike-and-wave discharges and resting state brain activity by using EEG/fMRI in a patient with absence seizures. Epilepsia. 2006;47:444-448.
41. Blumenfeld H, McNally KA, Vanderhill SD, et al. Positive and negative network correlations in temporal lobe epilepsy. Cereb Cortex. 2004;14:892-902.
42. Bassetti C, Vella S, Donati F, et al. SPECT during sleepwalking. Lancet. 2000;356: 484-485.
43. Tononi G, Laureys S. The neurology of consciousness. In: Laureys S, Tononi G, eds. Oxford: Academic Press; 2008. In press.
44. Laureys S, Faymonville ME, Moonen G, et al. PET scanning and neuronal loss in acute vegetative state. Lancet. 2000;355:1825-1826.
45. Vogt BA, Laureys S. Posterior cingulate, precuneal and retrosplenial cortices: cytology and components of the neural network correlates of consciousness. Prog Brain Res. 2005;150:205-217.
46. Kaisti KK, Metsahonkala L, Teras M, et al. Effects of surgical levels of propofol and sevoflurane anesthesia on cerebral blood flow in healthy subjects studied with positron emission tomography. Anesthesiology. 2002;96:1358-1370.
47. Bonhomme V, Fiset P, Meuret P, et al. Propofol anesthesia and cerebral blood flow changes elicited by vibrotactile stimulation: a positron emission tomography study. J Neurophysiol. 2001;85:1299-1308.
48. Laureys S, Boly M, Maquet P. Tracking the recovery of consciousness from coma. J Clin Invest. 2006;116:1823-1825.
49. Maquet P, Ruby P, Maudoux A, et al. Human cognition during REM sleep and the activity profile within frontal and parietal cortices: a reappraisal of functional neuroimaging data. Prog Brain Res. 2005;150:219-227.
50. Rex S, Meyer PT, Baumert JH, et al. Positron emission tomography study of regional cerebral blood flow and flow-metabolism coupling during general anaesthesia with xenon in humans. Br J Anaesth. 2008;100:667-675.
51. Alkire MT, Haier RJ, Fallon JH. Toward a unified theory of narcosis: brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness. Conscious Cogn. 2000;9:370-386.
52. White NS, Alkire MT. Impaired thalamocortical connectivity in humans during general-anesthetic-induced unconsciousness. Neuroimage. 2003;19:402-411.
53. Velly LJ, Rey MF, Bruder NJ, et al. Differential dynamic of action on cortical and subcortical structures of anesthetic agents during induction of anesthesia. Anesthe-siology. 2007;107:202-212.
54. Maquet P, Faymonville ME, Degueldre C, et al. Functional neuroanatomy of hypnotic state. Biol Psychiatry. 1999;45:327-333.
55. Rainville P, Hofbauer RK, Paus T, et al. Cerebral mechanisms of hypnotic induction and suggestion. J Cogn Neurosci. 1999;11:110-125.
56. Minoshima S, Giordani B, Berent S, et al. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer's disease. Ann Neurol. 1997;42:85-94.
57. Salmon E, Collette F, Degueldre C, et al. Voxel-based analysis of confounding effects of age and dementia severity on cerebral metabolism in Alzheimer's disease. Hum Brain Mapp. 2000;10:39-48.
58. Aupee AM, Desgranges B, Eustache F, et al. Voxel-based mapping of brain hypometabolism in permanent amnesia with PET. Neuroimage. 2001;13: 1164-1173.
59. Vogt BA, Finch DM, Olson CR. Functional heterogeneity in cingulate cortex: the anterior executive and posterior evaluative regions. Cereb Cortex. 1992;2: 435-443.
60. Friston K. Beyond phrenology: what can neuroimaging tell us about distributed circuitry? Annu Rev Neurosci. 2002;25:221-250.
61. Laureys S, Peigneux P, Goldman S. Biological psychiatry. In: D'haenen H, den Boer JA, Willner P, eds. Biological Psychiatry. New York: John Wiley & Sons Ltd; 2002: 155-166.
62. Laureys S, Faymonville ME, Goldman S, et al. Physiological imaging of the brain with PET. In: Gjedde A, Hansen SB, Knudsen GM, et al, eds. Physiological Imaging of the Brain With PET. San Diego: Academic Press; 2000:329-334.
63. Laureys S, Faymonville ME, Luxen A, et al. Restoration of thalamocortical connectivity after recovery from persistent vegetative state. Lancet. 2000;355: 1790-1791.
64. Schiff ND, Giacino JT, Kalmar K, et al. Behavioural improvements with thalamic stimulation after severe traumatic brain injury. Nature. 2007;448:600-603.
65. Alkire MT, Miller J. General anesthesia and the neural correlates of consciousness. Prog Brain Res. 2005;150:229-244.
66. Portas CM, Krakow K, Allen P, et al. Auditory processing across the sleep-wake cycle: simultaneous EEG and fMRI monitoring in humans. Neuron. 2000;28:991-999.
67. Plourde G, Belin P, Chartrand D, et al. Cortical processing of complex auditory stimuli during alterations of consciousness with the general anesthetic propofol. Anesthesiology. 2006;104:448-457.
68. Heinke W, Fiebach CJ, Schwarzbauer C, et al. Sequential effects of propofol on functional brain activation induced by auditory language processing: an event-related functional magnetic resonance imaging study. Br J Anaesth. 2004;92:641-650.
69. Veselis RA, Feshchenko VA, Reinsel RA, et al. Propofol and thiopental do not interfere with regional cerebral blood flow response at sedative concentrations. Anesthesiology. 2005;102:26-34.
70. Kerssens C, Hamann S, Peltier S, et al. Attenuated brain response to auditory word stimulation with sevoflurane: a functional magnetic resonance imaging study in humans. Anesthesiology. 2005;103:11-19.
71. Davis MH, Coleman MR, Absalom AR, et al. Dissociating speech perception and comprehension at reduced levels of awareness. Proc Natl Acad Sci USA. 2007;104: 16032-16037.
72. Antognini JF, Buonocore MH, Disbrow EA, et al. Isoflurane anesthesia blunts cerebral responses to noxious and innocuous stimuli: a fMRI study. Life Sci. 1997;61:349-354.
73. Hofbauer RK, Fiset P, Plourde G, et al. Dose-dependent effects of propofol on the central processing of thermal pain. Anesthesiology. 2004;100:386-394.
74. Di HB, Yu SM, Weng XC, et al. Cerebral response to patient's own name in the vegetative and minimally conscious states. Neurology. 2007;68:895-899.
75. Laureys S, Faymonville ME, Degueldre C, et al. Auditory processing in the vegetative state. Brain. 2000;123:1589-1601.
76. Laureys S, Faymonville ME, Peigneux P, et al. Cortical processing of noxious somatosensory stimuli in the persistent vegetative state. Neuroimage. 2002;17: 732-741.
77. Boly M, Faymonville ME, Peigneux P, et al. Auditory processing in severely brain injured patients: differences between the minimally conscious state and the persistent vegetative state. Arch Neurol. 2004;61:233-238.
78. Crick F, Koch C. Are we aware of neural activity in primary visual cortex? Nature. 1995;375:121-123.