ApoA-I facilitates ABCA1 recycle/accumulation to cell surface by inhibiting its intracellular degradation and increases HDL generation

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 28, Issue 10, 2008, Pages 1820-1824

  Lu, Rui ^a   Arakawa, Reijiro ^a   Ito Osumi, Chisato ^a   Iwamoto, Noriyuki ^a   Yokoyama, Shinji ^a  

^a NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

ABCA1; ApoA I; Calpain; Cholesterol; Endocytosis; HDL

Indexed keywords

ABC TRANSPORTER A1; APOLIPOPROTEIN A1; BIOTIN; HIGH DENSITY LIPOPROTEIN; ABC TRANSPORTER; APOA1 PROTEIN, HUMAN; CALPAIN;

ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; ANIMAL; BIOTINYLATION; CELL MEMBRANE; CELL STRAIN 3T3; FIBROBLAST; HUMAN; MACROPHAGE; METABOLISM; PROTEIN TRANSPORT; TIME;

ANIMALS; APOLIPOPROTEIN A-I; ATP-BINDING CASSETTE TRANSPORTERS; BALB 3T3 CELLS; BIOTINYLATION; CALPAIN; CELL MEMBRANE; ENDOCYTOSIS; FIBROBLASTS; HUMANS; LIPOPROTEINS, HDL; MACROPHAGES; MICE; PROTEIN TRANSPORT; TIME FACTORS;

EID: 53449094470     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.108.169482     Document Type: Article

References (32)

1. Yokoyama S. Assembly of high-density lipoprotein. Arterioscler Thromb Vasc Biol. 2006;26:20-27.
2. Okuhira K, Tsujita M, Yamauchi Y, Abe-Dohmae S, Kato K, Handa T, Yokoyama S. Potential involvement of dissociated apoA-I in the ABCA1-dependent cellular lipid release by HDL. J Lipid Res. 2004;45:645-652.
3. Tsujita M, Wu CA, Abe-Dohmae S, Usui S, Okazaki M, Yokoyama S. On the hepatic mechanism of HDL assembly by the ABCA1/apoA-I pathway. J Lipid Res. 2005;46:154-162.
4. Yamauchi Y, Abe-Dohmae S, Yokoyama S. Differential regulation of apolipoprotein A-I/ATP binding cassette transporter A1-mediated cholesterol and phospholipid release. Biochim Biophys Acta. 2002; 1585:1-10.
5. Hayashi M, Abe-Dohmae S, Okazaki M, Ueda K, Yokoyama S. Heterogeneity of high density lipoprotein generated by ABCA1 and ABCA7. J Lipid Res. 2005;46:1703-1711.
6. Venkateswaran A, Laffitte BA, Joseph SB, Mak PA, Wilpitz DC, Edwards PA, Tontonoz P. Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha. Proc Natl Acad Sci U S A. 2000; 97:12097-12102.
7. Tamehiro N, Shigemoto-Mogami Y, Kakeya T, Okuhira K, Suzuki K, Sato R, Nagao T, Nishimaki-Mogami T. Sterol regulatory element-binding protein-2- and liver X receptor-driven dual promoter regulation of hepatic ABC transporter A1 gene expression: mechanism underlying the unique response to cellular cholesterol status. J Biol Chem. 2007;282: 21090-21099.
8. Iwamoto N, Abe-Dohmae S, Ayaori M, Tanaka N, Kusuhara M, Ohsuzu F, Yokoyama S. ATP-binding cassette transporter A1 gene transcription is downregulated by activator protein 2alpha. Doxazosin inhibits activator protein 2alpha and increases high-density lipoprotein biogenesis independent of alpha1-adrenoceptor blockade. Circ Res. 2007;101:156-165.
9. Arakawa R, Yokoyama S. Helical apolipoproteins stabilize ATP-binding cassette transporter A1 by protecting it from thiol protease-mediated degradation. J Biol Chem. 2002;277:22426-22429.
10. Arakawa R, Hayashi M, Remaley AT, Brewer BH Jr, Yamauchi Y, Yokoyama S. Phosphorylation and stabilization of ATP binding cassette transporter A1 by synthetic amphiphilic helical peptides. J Biol Chem. 2004;279:6217-6220.
11. Neufeld EB, Remaley AT, Demosky SJ, Stonik JA, Cooney AM, Comly M. Dwyer NK, Zhang M, Blanchette-Mackie J, Santamarina-Fojo S, Brewer HB Jr. Cellular localization and trafficking of the human ABCA1 transporter. J Biol Chem. 2001;276:27584-27590.
12. Neufeld EB, Stonik JA, Demosky SJ Jr, Knapper CL, Combs CA, Cooney A, Comly M, Dwyer N, Blanchette-Mackie J, Remaley AT, Santamarina-Fojo S, Brewer HB Jr. The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease. J Biol Chem. 2004;279:15571-15578.
13. Takahashi Y, Smith JD. Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway. Proc Natl Acad Sci U S A. 1999;96:11358-11363.
14. Chen W, Sun Y, Welch C, Gorelik A, Leventhal AR, Tabas I, Tall AR. Preferential ATP-binding cassette transporter A1-mediated cholesterol efflux from late endosomes/lysosomes. J Biol Chem. 2001;276:43564-43569.
15. Smith JD, Waelde C, Horwitz A, Zheng P. Evaluation of the role of phosphatidylserine translocase activity in ABCA1-mediated lipid efflux. J Biol Chem. 2002;277:17797-17803.
16. Hassan HH, Bailey D, Lee DY, Iatan I, Hafiane A, Ruel I, Krimbou L, Genest J. Quantitative analysis of ABCA1-dependent compartmentalization and trafficking of apolipoprotein A-I: Implications for determining cellular kinetics of nascent HDL biogenesis. J Biol Chem. 2008; 283:11164-11175.
17. Munehira Y, Ohnishi T, Kawamoto S, Furuya A, Shitara K, Imamura M, Yokota T, Takeda S, Amachi T, Matsuo M, Kioka N, Ueda K. a1-syntrophin modulates turnover of ABCA1. J Biol Chem. 2004;279: 15091-15095.
18. Okuhira K, Fitzgerald ML, Sarracino DA, Manning JJ, Bell SA, Goss JL, Freeman MW. Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux. J Biol Chem. 2005;280:39653-39664.
19. Chen W, Wang N, Tall AR. A PEST deletion mutant of ABCA1 shows impaired identification and defective cholesterol efflux from late endosomes. J Biol Chem. 2005;280:29277-29281.
20. Witting SR, Maiorano JN, Davidson WS. Ceramide enhances cholesterol efflux to apolipoprotein A-I by increasing the cell surface presence of ATP-binding cassette transporter A1. J Biol Chem. 2003;278:40121-40127.
21. Faulkner LE, Panagotopulos SE, Johnson JD, Woollett LA, Hui DY, Witting SR, Maiorano JN, Davidson WS. An analysis of the role of a retroendocytosis pathway in ATP-binding cassette transporter (ABCAI)-mediated cholesterol efflux from macrophages. J Lipid Res. 2008;49: 1322-1332.
22. Denis M, Landry YD, Aha X. ATP-binding cassette A1-mediated lipidation of apolipoprotein A-I occurs at the plasma membrane and not in the endocytotic compartment. J Biol Chem. 2008;283:16178-16186.
23. Arakawa R, Tamehiro N, Nishimaki-Mogami T, Ueda K, Yokoyama S Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter AI gene in a liver X receptor-dependent manner. Arterioscler Thromb Vasc Biol. 2005;25: 1193-1197.
24. Yokoyama S, Tajima S, Yamamoto A. The process of dissolving apolipoprotein A-I in an aqueous buffer. J Biochem (Tokyo). 1982;91: 1267-1272.
25. von Boxberg Y, Wütz R, Schwarz U. Use of the biotin-avidin system for labelling, isolation and characterization of neural cell-surface proteins. Eur J Biochem. 1990;190:249-256.
26. Vagin O, Turdikulova S, Yakubov I, Sachs G. Use of the H.K-ATPase beta subunit to identify multiple sorting pathways for plasma membrane delivery in polarized cells. J Biol Chem. 2005;280:14741-14754.
27. Abe-Dohmae S, Suzuki S, Wada Y, Aburatani H, Vance DE, Yokoyama S. Characterization of apolipoprotein-mediated HDL generation induced by cAMP in a murine macrophage cell line. Biochemistry. 2000;39: 11092-11099.
28. Jackman MR, Shurety W, Ellis JA, Luzio JP. Inhibition of apical but not basolateral endocytosis of ricin and folate in Caco-2 cells by cytochalasin D. J Cell Sci. 1994;107: 2547-2556.
29. Szaszi K, Paulsen A, Szabo EZ, Numata M, Grinstein S, Orlowski J. Clathrin-mediated endocytosis and recycling of the neuron-specific Na+/H+ exchanger NHE5 isoform. Regulation by phosphatidylinositol 3′-kinase and the actin cytoskeleton. J Biol Chem. 2002;277: 42623-42632.
30. Hara H, Yokoyama S. Interaction of free apolipoproteins with macrophages. Formation of high density lipoprotein-like lipoproteins and reduction of cellular cholesterol. J Biol Chem. 1991;266:3080-3086.
31. Timmins JM, Lee JY, Boudyguina E, Kluckman KD, Brunham LR, Mulya A, Gebre AK, Coutinho JM, Colvin PL, Smith TL, Hayden MR, Maeda N, Parks JS. Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I. J Clin Invest. 2005;115:1333-1342.
32. Nanjee MN, Cooke CJ, Olszewski WL, Miller NE. Lipid and apolipoprotein concentrations in prenodal leg lymph of fasted humans. Associations with plasma concentrations in normal subjects, lipoprotein lipase deficiency, and LCAT deficiency. J Lipid Res. 2000;41:1317-1327.