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Volumn 19, Issue SUPPL. 7, 2008, Pages

Chronic lymphocytic leukaemia: A short overview

Author keywords

[No Author keywords available]

Indexed keywords

ALEMTUZUMAB; ALKYLATING AGENT; CHLORAMBUCIL; CORTICOSTEROID; CYCLOPHOSPHAMIDE; FLUDARABINE; MITOXANTRONE; RITUXIMAB;

EID: 53449089441     PISSN: 09237534     EISSN: 15698041     Source Type: Journal    
DOI: 10.1093/annonc/mdn460     Document Type: Conference Paper
Times cited : (31)

References (89)
  • 2
    • 0028822481 scopus 로고
    • Chronic lymphocytic leukemia
    • Rozman C, Montserrat E. Chronic lymphocytic leukemia. N Engl J Med 1995; 333: 1052-1057.
    • (1995) N Engl J Med , vol.333 , pp. 1052-1057
    • Rozman, C.1    Montserrat, E.2
  • 3
    • 2142650988 scopus 로고    scopus 로고
    • Biology and treatment of chronic lymphocytic leukemia
    • American Society of Hematology Education Program Book
    • Keating MJ, Chiorazzi N, Messmer B et al. Biology and treatment of chronic lymphocytic leukemia. Hematology 2003 (American Society of Hematology Education Program Book): 153-175.
    • (2003) Hematology , pp. 153-175
    • Keating, M.J.1    Chiorazzi, N.2    Messmer, B.3
  • 4
    • 0037616996 scopus 로고    scopus 로고
    • Ries LAG, Eismer MP, Kosary CL et al, eds, Bethesda, MD: National Cancer Institute
    • Ries LAG, Eismer MP, Kosary CL et al. (eds). SEER Cancer Statistics Review, 1993-1997. Bethesda, MD: National Cancer Institute 2000.
    • (2000) SEER Cancer Statistics Review, 1993-1997
  • 6
    • 36148946111 scopus 로고    scopus 로고
    • Acquired immune-related and inflammatory conditions and subsequent chronic lymphocytic leukaemia
    • Landgren O, Gridley G, Check D, Caporaso NE, Morris Brown L. Acquired immune-related and inflammatory conditions and subsequent chronic lymphocytic leukaemia. Br J Haematol 2007; 139: 791-798.
    • (2007) Br J Haematol , vol.139 , pp. 791-798
    • Landgren, O.1    Gridley, G.2    Check, D.3    Caporaso, N.E.4    Morris Brown, L.5
  • 7
    • 33847373538 scopus 로고    scopus 로고
    • Respiratory tract infections and subsequent risk of chronic lymphocytic leukemia
    • Landgren O, Rapkin JS, Caporaso NE et al. Respiratory tract infections and subsequent risk of chronic lymphocytic leukemia. Blood 2007; 109: 2198-2201.
    • (2007) Blood , vol.109 , pp. 2198-2201
    • Landgren, O.1    Rapkin, J.S.2    Caporaso, N.E.3
  • 8
    • 0026519320 scopus 로고
    • Increased incidence of hematologic malignancies in first-degree relatives of patients with chronic lymphocytic leukemia
    • Cuttner J. Increased incidence of hematologic malignancies in first-degree relatives of patients with chronic lymphocytic leukemia. Cancer Invest 1992; 10: 103-109.
    • (1992) Cancer Invest , vol.10 , pp. 103-109
    • Cuttner, J.1
  • 9
    • 0036785288 scopus 로고    scopus 로고
    • Inherited predisposition to CLL is detectable as sub-clinical monoclonal B-lymphocyte expansion
    • Rawstron C, Yuille R, Fuller R et al. Inherited predisposition to CLL is detectable as sub-clinical monoclonal B-lymphocyte expansion. Blood 2002; 100: 2289-2290.
    • (2002) Blood , vol.100 , pp. 2289-2290
    • Rawstron, C.1    Yuille, R.2    Fuller, R.3
  • 10
    • 0037100421 scopus 로고    scopus 로고
    • Monoclonal B lymphocytes with the characteristics of 'indolent' chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts
    • Rawstron AC, Green MJ, Kuzmicki A et al. Monoclonal B lymphocytes with the characteristics of 'indolent' chronic lymphocytic leukemia are present in 3.5% of adults with normal blood counts. Blood 2002; 100: 635-639.
    • (2002) Blood , vol.100 , pp. 635-639
    • Rawstron, A.C.1    Green, M.J.2    Kuzmicki, A.3
  • 11
    • 20044372326 scopus 로고    scopus 로고
    • In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukaemia B cells
    • Messmer BT, Messmer D, Allen SL et al. In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukaemia B cells. J Clin Invest 2005; 115: 755-764.
    • (2005) J Clin Invest , vol.115 , pp. 755-764
    • Messmer, B.T.1    Messmer, D.2    Allen, S.L.3
  • 13
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • Döhner H, Stilgenbauer S, Benner A et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med 2000; 343: 1910-1916.
    • (2000) N Engl J Med , vol.343 , pp. 1910-1916
    • Döhner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 14
    • 0033050007 scopus 로고    scopus 로고
    • Chromosome aberrations in B-cell chronic lymphocytic leukemia: Reassessment based on molecular cytogenetic analysis
    • Döhner H, Stilgenbauer S, Döhner K, Bentz M, Lichter P. Chromosome aberrations in B-cell chronic lymphocytic leukemia: Reassessment based on molecular cytogenetic analysis. J Mol Med 1999; 77: 266-281.
    • (1999) J Mol Med , vol.77 , pp. 266-281
    • Döhner, H.1    Stilgenbauer, S.2    Döhner, K.3    Bentz, M.4    Lichter, P.5
  • 15
    • 0030915891 scopus 로고    scopus 로고
    • Cytogenetic and molecular cytogenetic analysis of B cell chronic lymphocytic leukemia: Specific chromosome aberrations identify prognostic subgroups of patients and point to loci for candidate genes
    • Döhner H, Stilgenbauer S, Fischer K, Bentz M, Lichter P. Cytogenetic and molecular cytogenetic analysis of B cell chronic lymphocytic leukemia: Specific chromosome aberrations identify prognostic subgroups of patients and point to loci for candidate genes. Leukemia 1997; 11 (Suppl 2): S19-S24.
    • (1997) Leukemia , vol.11 , Issue.SUPPL. 2
    • Döhner, H.1    Stilgenbauer, S.2    Fischer, K.3    Bentz, M.4    Lichter, P.5
  • 16
    • 33750577939 scopus 로고    scopus 로고
    • Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia
    • Shanafelt TD, Witzig TE, Fink SR et al. Prospective evaluation of clonal evolution during long-term follow-up of patients with untreated early-stage chronic lymphocytic leukemia. J Clin Oncol 2006; 24: 4634-4641.
    • (2006) J Clin Oncol , vol.24 , pp. 4634-4641
    • Shanafelt, T.D.1    Witzig, T.E.2    Fink, S.R.3
  • 17
    • 36349025291 scopus 로고    scopus 로고
    • Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival
    • Stilgenbauer S, Sander S, Bullinger L et al. Clonal evolution in chronic lymphocytic leukemia: Acquisition of high-risk genomic aberrations associated with unmutated VH, resistance to therapy, and short survival. Haematologica 2007; 92: 1242-1245.
    • (2007) Haematologica , vol.92 , pp. 1242-1245
    • Stilgenbauer, S.1    Sander, S.2    Bullinger, L.3
  • 18
    • 0035312968 scopus 로고    scopus 로고
    • Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia
    • Migliazza A, Bosch F, Komatsu H et al. Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia. Blood 2001; 97: 2098-2104.
    • (2001) Blood , vol.97 , pp. 2098-2104
    • Migliazza, A.1    Bosch, F.2    Komatsu, H.3
  • 19
    • 0035884425 scopus 로고    scopus 로고
    • Characterization of the 13q14 tumor suppressor locus in CLL: Identification of ALT1, an alternative splice variant of the LEU2 gene
    • Bullrich F, Fujii H, Calin G et al. Characterization of the 13q14 tumor suppressor locus in CLL: Identification of ALT1, an alternative splice variant of the LEU2 gene. Cancer Res 2001; 61: 6640-6648.
    • (2001) Cancer Res , vol.61 , pp. 6640-6648
    • Bullrich, F.1    Fujii, H.2    Calin, G.3
  • 20
    • 27244434788 scopus 로고    scopus 로고
    • A micro RNA signature associated with prognosis and progression in chronic lymphocytic leukemia
    • Calin GA, Ferracin M, Cimmino A et al. A micro RNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med 2005; 353: 1793-1801.
    • (2005) N Engl J Med , vol.353 , pp. 1793-1801
    • Calin, G.A.1    Ferracin, M.2    Cimmino, A.3
  • 21
    • 34547854381 scopus 로고    scopus 로고
    • The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia
    • Calin GA, Pekarsky Y, Croce CM. The role of microRNA and other non-coding RNA in the pathogenesis of chronic lymphocytic leukemia. Best Pract Res Clin Haematol 2007; 20: 425-437.
    • (2007) Best Pract Res Clin Haematol , vol.20 , pp. 425-437
    • Calin, G.A.1    Pekarsky, Y.2    Croce, C.M.3
  • 22
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999; 94: 1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 23
    • 0033567968 scopus 로고    scopus 로고
    • Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood 1999; 94: 1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 24
    • 0023832314 scopus 로고
    • Serum immunoglobulins in B-chronic lymphocytic leukaemia. Natural history and prognostic significance
    • Rozman C, Montserrat E, Viñolas N et al. Serum immunoglobulins in B-chronic lymphocytic leukaemia. Natural history and prognostic significance. Cancer 1988; 61: 279-283.
    • (1988) Cancer , vol.61 , pp. 279-283
    • Rozman, C.1    Montserrat, E.2    Viñolas, N.3
  • 25
    • 0027316190 scopus 로고
    • Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases
    • Kipps TJ, Carson DA. Autoantibodies in chronic lymphocytic leukemia and related systemic autoimmune diseases. Blood 1993; 81: 2475-2487.
    • (1993) Blood , vol.81 , pp. 2475-2487
    • Kipps, T.J.1    Carson, D.A.2
  • 26
    • 0035382941 scopus 로고    scopus 로고
    • Autoimmunity in chronic lymphocytic leukemia
    • Ward JH. Autoimmunity in chronic lymphocytic leukemia. Curr Treat Options Oncol 2001; 2: 253-257.
    • (2001) Curr Treat Options Oncol , vol.2 , pp. 253-257
    • Ward, J.H.1
  • 27
    • 0028853728 scopus 로고
    • Fludarabine-related autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia
    • Myint H, Copplestone JA, Orchard J et al. Fludarabine-related autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia. Br J Haematol 1995; 91: 341-344.
    • (1995) Br J Haematol , vol.91 , pp. 341-344
    • Myint, H.1    Copplestone, J.A.2    Orchard, J.3
  • 28
    • 0031422845 scopus 로고    scopus 로고
    • Complications in the treatment of CLL with purine analogues
    • Juliusson G. Complications in the treatment of CLL with purine analogues. Hematol Cell Ther 1997; 39 (Suppl 1): S41-S44.
    • (1997) Hematol Cell Ther , vol.39 , Issue.SUPPL. 1
    • Juliusson, G.1
  • 29
    • 0000421361 scopus 로고
    • Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukaemia
    • Richter MN. Generalized reticular cell sarcoma of lymph nodes associated with lymphatic leukaemia. Am J Pathol 1928; 4: 285-292.
    • (1928) Am J Pathol , vol.4 , pp. 285-292
    • Richter, M.N.1
  • 30
    • 33744800308 scopus 로고    scopus 로고
    • Clinical outcomes and prognostic factors in patients with Richter's syndrome treated with chemotherapy or chemoimmunotherapy with or without stem-cell transplantation
    • Tsimberidou AM, O'Brien S, Khouri I et al. Clinical outcomes and prognostic factors in patients with Richter's syndrome treated with chemotherapy or chemoimmunotherapy with or without stem-cell transplantation. J Clin Oncol 2006; 24: 2343-2351.
    • (2006) J Clin Oncol , vol.24 , pp. 2343-2351
    • Tsimberidou, A.M.1    O'Brien, S.2    Khouri, I.3
  • 31
    • 0028031704 scopus 로고
    • Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequent large cell lymphoma)
    • Matolcsy A, Inghirami G, Knowles DM. Molecular genetic demonstration of the diverse evolution of Richter's syndrome (chronic lymphocytic leukemia and subsequent large cell lymphoma). Blood 1994; 83: 1363-1372.
    • (1994) Blood , vol.83 , pp. 1363-1372
    • Matolcsy, A.1    Inghirami, G.2    Knowles, D.M.3
  • 32
    • 33749054253 scopus 로고    scopus 로고
    • Detection of Richter's transformation of chronic lymphocytic leukemia by PET/CT
    • Bruzzi JF, Macapinlac H, Tsimberidou AM et al. Detection of Richter's transformation of chronic lymphocytic leukemia by PET/CT. J Nucl Med 2006; 47: 1267-1273.
    • (2006) J Nucl Med , vol.47 , pp. 1267-1273
    • Bruzzi, J.F.1    Macapinlac, H.2    Tsimberidou, A.M.3
  • 33
    • 34748861564 scopus 로고    scopus 로고
    • IgVH mutational status and clonality analysis of Richter's transformation: Diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution
    • Mao Z, Quintanilla-Martinez L, Raffeld M et al. IgVH mutational status and clonality analysis of Richter's transformation: Diffuse large B-cell lymphoma and Hodgkin lymphoma in association with B-cell chronic lymphocytic leukemia (B-CLL) represent 2 different pathways of disease evolution. Am J Surg Pathol 2007; 31: 1605-1614.
    • (2007) Am J Surg Pathol , vol.31 , pp. 1605-1614
    • Mao, Z.1    Quintanilla-Martinez, L.2    Raffeld, M.3
  • 34
    • 13844255162 scopus 로고    scopus 로고
    • Richter's transformation of chronic lymphocytic leukemia. The possible role of fludarabine and the Epstein-Barr virus in its pathogenesis
    • Thornton PD, Bellas C, Santon A et al. Richter's transformation of chronic lymphocytic leukemia. The possible role of fludarabine and the Epstein-Barr virus in its pathogenesis. Leuk Res 2005; 29: 389-395.
    • (2005) Leuk Res , vol.29 , pp. 389-395
    • Thornton, P.D.1    Bellas, C.2    Santon, A.3
  • 35
    • 0028345579 scopus 로고
    • Infections in chronic lymphocytic leukemia: Risk factors and impact on survival, and treatment
    • Molica S. Infections in chronic lymphocytic leukemia: Risk factors and impact on survival, and treatment. Leuk Lymphoma 1994; 13: 203-214.
    • (1994) Leuk Lymphoma , vol.13 , pp. 203-214
    • Molica, S.1
  • 36
    • 43449109584 scopus 로고    scopus 로고
    • Management of infectious complications in patients with chronic lymphocytic leukemia
    • Morrison VA. Management of infectious complications in patients with chronic lymphocytic leukemia. Hematology Am Soc Hematol Educ Program 2007: 332-338.
    • (2007) Hematology Am Soc Hematol Educ Program , pp. 332-338
    • Morrison, V.A.1
  • 37
    • 0018084656 scopus 로고
    • Subsequent cancer in patients with chronic lymphocytic leukemia. A possible immunologic mechanism
    • Greene MH, Hoover RN, Fraumeni JF. Subsequent cancer in patients with chronic lymphocytic leukemia. A possible immunologic mechanism. J Natl Cancer Inst 1978; 61: 337-340.
    • (1978) J Natl Cancer Inst , vol.61 , pp. 337-340
    • Greene, M.H.1    Hoover, R.N.2    Fraumeni, J.F.3
  • 38
    • 33846842385 scopus 로고    scopus 로고
    • Risk of second malignant neoplasms among lymphoma patients with a family history of cancer
    • Landgren O, Pfeiffer RM, Stewart L et al. Risk of second malignant neoplasms among lymphoma patients with a family history of cancer. Int J Cancer 2007; 120: 1099-1102.
    • (2007) Int J Cancer , vol.120 , pp. 1099-1102
    • Landgren, O.1    Pfeiffer, R.M.2    Stewart, L.3
  • 39
    • 0035885968 scopus 로고    scopus 로고
    • Solid tumors after chronic lymphocytic leukemia
    • Hisada M, Biggar RJ, Greene MH et al. Solid tumors after chronic lymphocytic leukemia. Blood 2001; 98: 1979-1981.
    • (2001) Blood , vol.98 , pp. 1979-1981
    • Hisada, M.1    Biggar, R.J.2    Greene, M.H.3
  • 40
    • 45149100665 scopus 로고    scopus 로고
    • Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) updating the National Cancer Institute- Working Group (NCI-WG) 1996 guidelines
    • In press
    • Hallek M, Cheson BD, Catovsky D. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: A report from the International Workshop on Chronic Lymphocytic Leukemia (IWCLL) updating the National Cancer Institute- Working Group (NCI-WG) 1996 guidelines. Blood 2008; In press.
    • (2008) Blood
    • Hallek, M.1    Cheson, B.D.2    Catovsky, D.3
  • 41
    • 0016740933 scopus 로고
    • Clinical staging of chronic lymphocytic leukemia
    • Rai KR, Sawitsky A, Cronkite EP et al. Clinical staging of chronic lymphocytic leukemia. Blood 1975; 46: 219-234.
    • (1975) Blood , vol.46 , pp. 219-234
    • Rai, K.R.1    Sawitsky, A.2    Cronkite, E.P.3
  • 42
    • 0019427092 scopus 로고
    • A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
    • Binet JL, Auquier A, Dighiero G et al. A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis. Cancer 1981; 48: 198-206.
    • (1981) Cancer , vol.48 , pp. 198-206
    • Binet, J.L.1    Auquier, A.2    Dighiero, G.3
  • 43
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated IgV(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood 1999; 94: 1848-1854.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 44
    • 0033567968 scopus 로고    scopus 로고
    • Ig VH gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle FIN, Wasil T, Fais F et al. Ig VH gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia, Blood 1999; 94: 1840-1847.
    • (1999) Blood , vol.94 , pp. 1840-1847
    • Damle, F.I.N.1    Wasil, T.2    Fais, F.3
  • 45
    • 0037103212 scopus 로고    scopus 로고
    • IgVH mutation status, CD38 expression level, genomic aberrations, and prognosis in chronic lymphocytic leukemia
    • Krober A, Seiler T, Benner A et al. IgVH mutation status, CD38 expression level, genomic aberrations, and prognosis in chronic lymphocytic leukemia. Blood 2002; 100: 1410-1416.
    • (2002) Blood , vol.100 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3
  • 46
    • 0642281445 scopus 로고    scopus 로고
    • Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia
    • Vasconcelos Y, Davi F, Levy V et al. Binet's staging system and VH genes are independent but complementary prognostic indicators in chronic lymphocytic leukemia. J Clin Oncol 2003; 21: 3928-3932.
    • (2003) J Clin Oncol , vol.21 , pp. 3928-3932
    • Vasconcelos, Y.1    Davi, F.2    Levy, V.3
  • 47
    • 23844444499 scopus 로고    scopus 로고
    • Prognostic usage of V(H) gene mutation status and its surrogates markers and the role of antigen selection in chronic lymphocytic leukemia
    • Tobin G, Rosenquist R. Prognostic usage of V(H) gene mutation status and its surrogates markers and the role of antigen selection in chronic lymphocytic leukemia. Med Oncol 2005; 22: 217-228.
    • (2005) Med Oncol , vol.22 , pp. 217-228
    • Tobin, G.1    Rosenquist, R.2
  • 48
    • 33645507226 scopus 로고    scopus 로고
    • Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
    • Thorsélius M, Knöber A, Murray F et al. Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. Blood 2006; 107: 2889-2894.
    • (2006) Blood , vol.107 , pp. 2889-2894
    • Thorsélius, M.1    Knöber, A.2    Murray, F.3
  • 49
    • 0036464608 scopus 로고    scopus 로고
    • CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease
    • Hamblin TJ, Orchad JA Ibbotson RE et al. CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukemia, but CD38 expression may vary during the course of the disease. Blood 2002; 99: 1023-1029.
    • (2002) Blood , vol.99 , pp. 1023-1029
    • Hamblin, T.J.1    Orchad, J.A.2    Ibbotson, R.E.3
  • 51
    • 26244458921 scopus 로고    scopus 로고
    • Surface-antigen expression profiling (SEP) in B-cell chronic lymphocytic leukaemia (B-CLL): Identification of markers with prognostic relevance
    • Zucchetto A, Sonego P, Degan M et al. Surface-antigen expression profiling (SEP) in B-cell chronic lymphocytic leukaemia (B-CLL): identification of markers with prognostic relevance. J Immunol Meth 2005; 305: 20-32.
    • (2005) J Immunol Meth , vol.305 , pp. 20-32
    • Zucchetto, A.1    Sonego, P.2    Degan, M.3
  • 52
    • 38349084386 scopus 로고    scopus 로고
    • Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia
    • Gattei V, Bulian P, Del Principe MI et al. Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia. Blood 2008; 111: 865-873.
    • (2008) Blood , vol.111 , pp. 865-873
    • Gattei, V.1    Bulian, P.2    Del Principe, M.I.3
  • 53
    • 0035803371 scopus 로고    scopus 로고
    • Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia
    • Rosenwald A, Alizadeh AA, Widhopf G et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001; 194: 1639-1647.
    • (2001) J Exp Med , vol.194 , pp. 1639-1647
    • Rosenwald, A.1    Alizadeh, A.A.2    Widhopf, G.3
  • 54
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia
    • Crespo M, Bosch F, Villamor N et al. ZAP-70 expression as a surrogate for immunoglobulin-variable-region mutations in chronic lymphocytic leukemia. N Engl J Med 2003; 348: 1764-1775.
    • (2003) N Engl J Med , vol.348 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3
  • 55
    • 0347318114 scopus 로고    scopus 로고
    • ZAP-70 expression and prognosis in chronic lymphocytic leukaemia
    • Orchard A Ibbotson RE, Davis Z et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004; 363: 105-111.
    • (2004) Lancet , vol.363 , pp. 105-111
    • Orchard, A.1    Ibbotson, R.E.2    Davis, Z.3
  • 56
    • 4143105617 scopus 로고    scopus 로고
    • ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia
    • Rassenti LZ, Huynh L, Toy TL et al. ZAP-70 compared with immunoglobulin heavy-chain gene mutation status as a predictor of disease progression in chronic lymphocytic leukemia. N Engl J Med 2004; 351: 893-901.
    • (2004) N Engl J Med , vol.351 , pp. 893-901
    • Rassenti, L.Z.1    Huynh, L.2    Toy, T.L.3
  • 57
    • 33746589459 scopus 로고    scopus 로고
    • Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia
    • Del Principe MI, Del Poeta G, Buccisano F et al. Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia. Blood 2006; 108: 853-861.
    • (2006) Blood , vol.108 , pp. 853-861
    • Del Principe, M.I.1    Del Poeta, G.2    Buccisano, F.3
  • 58
    • 33644881106 scopus 로고    scopus 로고
    • Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia
    • Krober A, Bloehdom J, Hafner S et al. Additional genetic high-risk features such as 11q deletion, 17p deletion, and V3-21 usage characterize discordance of ZAP-70 and VH mutation status in chronic lymphocytic leukemia. J Clin Oncol 2006; 24: 969-975.
    • (2006) J Clin Oncol , vol.24 , pp. 969-975
    • Krober, A.1    Bloehdom, J.2    Hafner, S.3
  • 59
    • 27644515517 scopus 로고    scopus 로고
    • Zeta-chain associated protein 70 and CD38 combined predict the time to first treatment in patients with chronic lymphocytic leukemia
    • Del Diudice I, Morilla A, Osuji N et al. Zeta-chain associated protein 70 and CD38 combined predict the time to first treatment in patients with chronic lymphocytic leukemia. Cancer 2005; 104: 2124-2132.
    • (2005) Cancer , vol.104 , pp. 2124-2132
    • Del Diudice, I.1    Morilla, A.2    Osuji, N.3
  • 60
    • 18644382787 scopus 로고    scopus 로고
    • Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia
    • Schroers R, Griesinger F, Trümper L et al. Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia. Leukemia 2005; 19: 750-758.
    • (2005) Leukemia , vol.19 , pp. 750-758
    • Schroers, R.1    Griesinger, F.2    Trümper, L.3
  • 61
    • 33645296285 scopus 로고    scopus 로고
    • The clinical significance of ZAP-70 and CD38 expression in B-cell chronic lymphocytic leukaemia
    • Hus I, Podhorecka M, Bojarska-Junak A et al. The clinical significance of ZAP-70 and CD38 expression in B-cell chronic lymphocytic leukaemia. Ann Oncol 2006; 17: 683-690.
    • (2006) Ann Oncol , vol.17 , pp. 683-690
    • Hus, I.1    Podhorecka, M.2    Bojarska-Junak, A.3
  • 62
    • 23044510136 scopus 로고    scopus 로고
    • Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukaemia
    • Keating MJ, O'Brien S, Albitar M et al. Early results of a chemoimmunotherapy regimen of fludarabine, cyclophosphamide, and rituximab as initial therapy for chronic lymphocytic leukaemia. J Clin Oncol 2005; 23: 1-8.
    • (2005) J Clin Oncol , vol.23 , pp. 1-8
    • Keating, M.J.1    O'Brien, S.2    Albitar, M.3
  • 63
    • 27744507174 scopus 로고    scopus 로고
    • Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia
    • Wierda W, O'Brien S, Wen S et al. Chemoimmunotherapy with fludarabine, cyclophosphamide, and rituximab for relapsed and refractory chronic lymphocytic leukemia. J Clin Oncol 2005; 223: 40-47.
    • (2005) J Clin Oncol , vol.223 , pp. 40-47
    • Wierda, W.1    O'Brien, S.2    Wen, S.3
  • 64
    • 33644847307 scopus 로고    scopus 로고
    • Selected high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: Justification for risk-adapted therapy
    • Byrd JC, Gribben JG, Peterson BL et al. Selected high-risk genetic features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukemia: Justification for risk-adapted therapy. J Clin Oncol 2006; 24: 437-443.
    • (2006) J Clin Oncol , vol.24 , pp. 437-443
    • Byrd, J.C.1    Gribben, J.G.2    Peterson, B.L.3
  • 65
    • 34447530283 scopus 로고    scopus 로고
    • Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomised controlled trial
    • Catovsky D, Richards S, Matutes E et al. Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 Trial): A randomised controlled trial. Lancet 2007; 370: 230-239.
    • (2007) Lancet , vol.370 , pp. 230-239
    • Catovsky, D.1    Richards, S.2    Matutes, E.3
  • 66
    • 33947544426 scopus 로고    scopus 로고
    • Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US Intergroup Phase III Trial E2997
    • Grever MR, Lucas DM, Dewald GW et al. Comprehensive assessment of genetic and molecular features predicting outcome in patients with chronic lymphocytic leukemia: Results from the US Intergroup Phase III Trial E2997. J Clin Oncol 2007; 25: 799-804.
    • (2007) J Clin Oncol , vol.25 , pp. 799-804
    • Grever, M.R.1    Lucas, D.M.2    Dewald, G.W.3
  • 67
    • 54349113284 scopus 로고    scopus 로고
    • Lin KI, Tam CS, Abruzzo LV et al. IgVH mutational status does not affect complete remission rate but is associated with reduced remission duration in CLL patients treated with fludarabine, cyclophosphamide and rituximab (FCR)-based therapy [abstract]. Blood 2007; 110: (abstract 753).
    • Lin KI, Tam CS, Abruzzo LV et al. IgVH mutational status does not affect complete remission rate but is associated with reduced remission duration in CLL patients treated with fludarabine, cyclophosphamide and rituximab (FCR)-based therapy [abstract]. Blood 2007; 110: (abstract 753).
  • 68
    • 0344729013 scopus 로고    scopus 로고
    • Chlorambucil in indolent chronic lymphocytic leukemia
    • Dighiero G, Maloum K, Desablens B et al. Chlorambucil in indolent chronic lymphocytic leukemia. N Engl J Med 1998; 338: 1506-1511.
    • (1998) N Engl J Med , vol.338 , pp. 1506-1511
    • Dighiero, G.1    Maloum, K.2    Desablens, B.3
  • 69
    • 0033583824 scopus 로고    scopus 로고
    • Chemotherapeutic options in chronic lymphocytic leukemia: A meta-analysis of the randomized trials. CLL Trialists' Collaborative Group
    • Chemotherapeutic options in chronic lymphocytic leukemia: A meta-analysis of the randomized trials. CLL Trialists' Collaborative Group. J Natl Cancer Inst 1999; 91: 861-868.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 861-868
  • 70
    • 15844368449 scopus 로고    scopus 로고
    • The French Cooperative Group on CLL. Multicentre prospective randomized trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukemia
    • Johnson S, Smith AG et al. The French Cooperative Group on CLL. Multicentre prospective randomized trial of fludarabine versus cyclophosphamide, doxorubicin, and prednisone (CAP) for treatment of advanced-stage chronic lymphocytic leukemia. Lancet 1996; 347: 1432-1438.
    • (1996) Lancet , vol.347 , pp. 1432-1438
    • Johnson, S.1    Smith, A.G.2
  • 71
    • 0034649696 scopus 로고    scopus 로고
    • Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia
    • Rai KR, Peterson BL, Appelbaum FR et al. Fludarabine compared with chlorambucil as primary therapy for chronic lymphocytic leukemia. N Engl J Med 2000; 343: 1750-1757.
    • (2000) N Engl J Med , vol.343 , pp. 1750-1757
    • Rai, K.R.1    Peterson, B.L.2    Appelbaum, F.R.3
  • 72
    • 0035889147 scopus 로고    scopus 로고
    • Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients
    • Leporrier M, Chevret S, Cazin B et al. Randomized comparison of fludarabine, CAP, and ChOP in 938 previously untreated stage B and C chronic lymphocytic leukemia patients. Blood 2001; 98: 2319-2325.
    • (2001) Blood , vol.98 , pp. 2319-2325
    • Leporrier, M.1    Chevret, S.2    Cazin, B.3
  • 73
    • 31544434508 scopus 로고    scopus 로고
    • German CLL Study Group. Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia
    • Eichhorst BF, Busch R, Hopfinger G et al. German CLL Study Group. Fludarabine plus cyclophosphamide versus fludarabine alone in first-line therapy of younger patients with chronic lymphocytic leukemia. Blood 2006; 107: 885-891.
    • (2006) Blood , vol.107 , pp. 885-891
    • Eichhorst, B.F.1    Busch, R.2    Hopfinger, G.3
  • 74
    • 40749128044 scopus 로고    scopus 로고
    • Fludarabine, cyclophosphamide and mitoxantrone as intial therapy of chronic lymphocytic leukemia: High response rate and disease eradication
    • Bosch F, Ferrer A, Villamor N et al. Fludarabine, cyclophosphamide and mitoxantrone as intial therapy of chronic lymphocytic leukemia: High response rate and disease eradication. Clin Cancer Res 2008; 14: 155-161.
    • (2008) Clin Cancer Res , vol.14 , pp. 155-161
    • Bosch, F.1    Ferrer, A.2    Villamor, N.3
  • 75
    • 0036683449 scopus 로고    scopus 로고
    • Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL)
    • Lundin J, Kimby E, Björkholm M et al. Phase II trial of subcutaneous anti-CD52 monoclonal antibody alemtuzumab (Campath-1H) as first-line treatment for patients with B-cell chronic lymphocytic leukemia (B-CLL). Blood 2002; 100: 768-773.
    • (2002) Blood , vol.100 , pp. 768-773
    • Lundin, J.1    Kimby, E.2    Björkholm, M.3
  • 76
    • 37649004407 scopus 로고    scopus 로고
    • Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia
    • Hillmen P, Skotnicki AB, Robak T et al. Alemtuzumab compared with chlorambucil as first-line therapy for chronic lymphocytic leukemia. J Clin Oncol 2007; 25: 5616-5623.
    • (2007) J Clin Oncol , vol.25 , pp. 5616-5623
    • Hillmen, P.1    Skotnicki, A.B.2    Robak, T.3
  • 77
    • 21144456107 scopus 로고    scopus 로고
    • Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after therapy with alemtuzumab is associated with prolonged survival
    • Moreton P, Kennedy B, Lucas G et al. Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after therapy with alemtuzumab is associated with prolonged survival. J Clin Oncol 2005; 23: 2971-2979.
    • (2005) J Clin Oncol , vol.23 , pp. 2971-2979
    • Moreton, P.1    Kennedy, B.2    Lucas, G.3
  • 78
    • 11144357657 scopus 로고    scopus 로고
    • Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions
    • Lozanski G, Heerema NA, Flinn IW et al. Alemtuzumab is an effective therapy for chronic lymphocytic leukemia with p53 mutations and deletions. Blood 2004; 103: 3278-3281.
    • (2004) Blood , vol.103 , pp. 3278-3281
    • Lozanski, G.1    Heerema, N.A.2    Flinn, I.W.3
  • 79
    • 0037085770 scopus 로고    scopus 로고
    • Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia
    • Kennedy B, Rawstron A, Carter C et al. Campath-1H and fludarabine in combination are highly active in refractory chronic lymphocytic leukemia. Blood 2002; 99: 2245-2257.
    • (2002) Blood , vol.99 , pp. 2245-2257
    • Kennedy, B.1    Rawstron, A.2    Carter, C.3
  • 80
    • 27244451794 scopus 로고    scopus 로고
    • Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: Results of a phase II trial
    • Elter T, Borchmann P, Schulz H et al. Fludarabine in combination with alemtuzumab is effective and feasible in patients with relapsed or refractory B-cell chronic lymphocytic leukemia: Results of a phase II trial. J Clin Oncol 2005; 23: 7024-7031.
    • (2005) J Clin Oncol , vol.23 , pp. 7024-7031
    • Elter, T.1    Borchmann, P.2    Schulz, H.3
  • 81
    • 85014257001 scopus 로고    scopus 로고
    • Autologous and allogeneic stem cell transplantation for chronic lymphocytic leukemia
    • Dreger P, Montserrat E. Autologous and allogeneic stem cell transplantation for chronic lymphocytic leukemia. Leukemia 2002; 16: 985-992.
    • (2002) Leukemia , vol.16 , pp. 985-992
    • Dreger, P.1    Montserrat, E.2
  • 82
    • 20644447584 scopus 로고    scopus 로고
    • Allogeneic stem-cell transplantation may overcome the adverse prognosis of unmutated VH gene in patients with chronic lymphocytic leukemia
    • Moreno C, Villamor N, Colomer D et al. Allogeneic stem-cell transplantation may overcome the adverse prognosis of unmutated VH gene in patients with chronic lymphocytic leukemia. J Clin Oncol 2005; 23: 3433-3438.
    • (2005) J Clin Oncol , vol.23 , pp. 3433-3438
    • Moreno, C.1    Villamor, N.2    Colomer, D.3
  • 83
    • 28844483804 scopus 로고    scopus 로고
    • Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia
    • Gribben JG, Zahrieh D, Stephans K et al. Autologous and allogeneic stem cell transplantations for poor-risk chronic lymphocytic leukemia. Blood 2005; 106: 4389-4396.
    • (2005) Blood , vol.106 , pp. 4389-4396
    • Gribben, J.G.1    Zahrieh, D.2    Stephans, K.3
  • 84
    • 38049141530 scopus 로고    scopus 로고
    • Outcomes after allogeneic hematopoietic cell transplantation with nonmyeloablative or myeloablative conditioning regimens for treatment of lymphoma and chronic lymphocytic leukemia
    • Sorror ML, Storer BE, Maloney DG et al. Outcomes after allogeneic hematopoietic cell transplantation with nonmyeloablative or myeloablative conditioning regimens for treatment of lymphoma and chronic lymphocytic leukemia. Blood 2008; 111: 446-452.
    • (2008) Blood , vol.111 , pp. 446-452
    • Sorror, M.L.1    Storer, B.E.2    Maloney, D.G.3
  • 85
    • 0037370910 scopus 로고    scopus 로고
    • Unmutated immunoglobulin variable heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia
    • Ritgen M, Lange A, Stilgenbauer S et al. Unmutated immunoglobulin variable heavy-chain gene status remains an adverse prognostic factor after autologous stem cell transplantation for chronic lymphocytic leukemia. Blood 2003; 101: 2049-2053.
    • (2003) Blood , vol.101 , pp. 2049-2053
    • Ritgen, M.1    Lange, A.2    Stilgenbauer, S.3
  • 86
    • 1642292996 scopus 로고    scopus 로고
    • The prognostic impact of autologous stem cell transplantation in patients with chronic lymphocytic leukemia: A risk-matched analysis based on the VH gene mutational status
    • Dreger P, Stilgenbauer S, Benner A et al. The prognostic impact of autologous stem cell transplantation in patients with chronic lymphocytic leukemia: A risk-matched analysis based on the VH gene mutational status. Blood 2004; 103: 2850-2858.
    • (2004) Blood , vol.103 , pp. 2850-2858
    • Dreger, P.1    Stilgenbauer, S.2    Benner, A.3
  • 87
    • 33845543049 scopus 로고    scopus 로고
    • Chronic Leukemia Working Party of the EBMT. Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: The EBMT transplant consensus
    • Dreger P, Corradini P, Kimby E et al. Chronic Leukemia Working Party of the EBMT. Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: The EBMT transplant consensus. Leukemia 2007; 21: 12-17.
    • (2007) Leukemia , vol.21 , pp. 12-17
    • Dreger, P.1    Corradini, P.2    Kimby, E.3
  • 88
    • 0038528397 scopus 로고    scopus 로고
    • Treatment-related mortality and graft-versus-leukemia activity after allogeneic stem cell transplantation for chronic lymphocytic leukemia using intensity-reduced conditioning
    • Dreger P, Brand R, Hansz J et al. Treatment-related mortality and graft-versus-leukemia activity after allogeneic stem cell transplantation for chronic lymphocytic leukemia using intensity-reduced conditioning. Leukemia 2003; 17: 841-848.
    • (2003) Leukemia , vol.17 , pp. 841-848
    • Dreger, P.1    Brand, R.2    Hansz, J.3
  • 89
    • 32644435470 scopus 로고    scopus 로고
    • How I treat refractory CLL
    • Montserrat E, Moreno C, Esteve J et al. How I treat refractory CLL. Blood 2006; 107: 1276-1283.
    • (2006) Blood , vol.107 , pp. 1276-1283
    • Montserrat, E.1    Moreno, C.2    Esteve, J.3


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