Long-term administration of antisense oligonucleotides into the paraspinal muscles of mdx mice reduces kyphosis

Journal of Applied Physiology

Volumn 105, Issue 2, 2008, Pages 662-668

  Laws, Nicola ^a   Cornford Nairn, Renée A ^a   Irwin, Nicole ^a   Johnsen, Russell ^b   Fletcher, Susan ^b   Wilton, Stephen D ^b   Hoey, Andrew J ^a  

^a UNIVERSITY OF SOUTHERN QUEENSLAND   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Duchenne muscular dystrophy; Exon skipping; mdx mouse

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; DYSTROPHIN; MUSCLE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INTERCOSTAL MUSCLE; KYPHOSIS; LATISSIMUS DORSI FLAP; MALE; MICROPHOTOGRAPHY; MOUSE; MUSCLE CONTRACTILITY; MUSCULAR DYSTROPHY; MYOFIBROSIS; NONHUMAN; PRIORITY JOURNAL; SKELETAL MUSCLE; AGING; ANIMAL; BIOSYNTHESIS; BREATHING MUSCLE; C57BL MOUSE; CYTOCHEMISTRY; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; INTRAMUSCULAR DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; MUSCLE CONTRACTION; PATHOLOGY; PHYSIOLOGY; SPINE; WESTERN BLOTTING; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

AGING; ANIMALS; BLOTTING, WESTERN; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; HISTOCYTOCHEMISTRY; INJECTIONS, INTRAMUSCULAR; KYPHOSIS; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED MDX; MUSCLE CONTRACTION; MUSCLE PROTEINS; MUSCLE, SKELETAL; OLIGONUCLEOTIDES, ANTISENSE; RESPIRATORY MUSCLES; SPINE;

EID: 53449086510     PISSN: 87507587     EISSN: 15221601     Source Type: Journal    
DOI: 10.1152/japplphysiol.00068.2008     Document Type: Article

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